JP6616407B2 - フォーカシング方法 - Google Patents

フォーカシング方法 Download PDF

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Publication number
JP6616407B2
JP6616407B2 JP2017517035A JP2017517035A JP6616407B2 JP 6616407 B2 JP6616407 B2 JP 6616407B2 JP 2017517035 A JP2017517035 A JP 2017517035A JP 2017517035 A JP2017517035 A JP 2017517035A JP 6616407 B2 JP6616407 B2 JP 6616407B2
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focus
value
values
imaging device
measure
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Japanese (ja)
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JP2017537337A5 (enExample
JP2017537337A (ja
Inventor
サントス マンソ コルテ−レアル、ホセ ペドロ
デ マトス ノラスコ ラマス、フランシスコ コレイア
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バイオサーフィット、 ソシエダッド アノニマ
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Priority claimed from GB201417170A external-priority patent/GB201417170D0/en
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    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/60—Control of cameras or camera modules
    • H04N23/67—Focus control based on electronic image sensor signals
    • H04N23/676—Bracketing for image capture at varying focusing conditions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/244—Devices for focusing using image analysis techniques
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/0075—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00 with means for altering, e.g. increasing, the depth of field or depth of focus
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/40—Optical focusing aids
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/28—Systems for automatic generation of focusing signals
    • G02B7/36—Systems for automatic generation of focusing signals using image sharpness techniques, e.g. image processing techniques for generating autofocus signals
    • G02B7/38—Systems for automatic generation of focusing signals using image sharpness techniques, e.g. image processing techniques for generating autofocus signals measured at different points on the optical axis, e.g. focussing on two or more planes and comparing image data
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N5/00—Details of television systems
    • H04N5/14—Picture signal circuitry for video frequency region
    • H04N5/144—Movement detection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1452—Adjustment of focus; Alignment
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/28—Systems for automatic generation of focusing signals

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Analytical Chemistry (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Signal Processing (AREA)
  • Multimedia (AREA)
  • Studio Devices (AREA)
  • Microscoopes, Condenser (AREA)
  • Automatic Focus Adjustment (AREA)
  • Focusing (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2017517035A 2014-09-29 2015-09-29 フォーカシング方法 Active JP6616407B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB201417170A GB201417170D0 (en) 2014-09-29 2014-09-29 Focusing method
PT10793214 2014-09-29
GB1417170.6 2014-09-29
PT107932 2014-09-29
PCT/EP2015/072416 WO2016050767A1 (en) 2014-09-29 2015-09-29 Focusing method

Publications (3)

Publication Number Publication Date
JP2017537337A JP2017537337A (ja) 2017-12-14
JP2017537337A5 JP2017537337A5 (enExample) 2018-11-08
JP6616407B2 true JP6616407B2 (ja) 2019-12-04

Family

ID=55629458

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017517035A Active JP6616407B2 (ja) 2014-09-29 2015-09-29 フォーカシング方法

Country Status (4)

Country Link
US (2) US9832366B2 (enExample)
EP (1) EP3202133B1 (enExample)
JP (1) JP6616407B2 (enExample)
WO (1) WO2016050767A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017174652A1 (en) 2016-04-06 2017-10-12 Biosurfit, S.A. Method and system for capturing images of a liquid sample
JP6997549B2 (ja) * 2017-07-11 2022-01-17 アークレイ株式会社 分析装置及び焦点合わせ方法
CN109782414B (zh) * 2019-03-01 2021-05-18 广州医软智能科技有限公司 一种基于无参考结构清晰度的自动调焦方法
CN118648020A (zh) * 2022-02-02 2024-09-13 贝克曼库尔特有限公司 测量血细胞图像的图像质量
CN117452619B (zh) * 2023-12-26 2024-03-05 西华大学 一种稀疏目标显微成像自动对焦方法、系统及存储介质

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JPH02257931A (ja) * 1988-12-24 1990-10-18 Hamamatsu Photonics Kk 血管内血流計測装置及び計測方法
JP2939647B2 (ja) * 1990-07-24 1999-08-25 シスメックス株式会社 フローイメージングサイトメータにおける自動焦点調整方法
US5889881A (en) * 1992-10-14 1999-03-30 Oncometrics Imaging Corp. Method and apparatus for automatically detecting malignancy-associated changes
US5932872A (en) * 1994-07-01 1999-08-03 Jeffrey H. Price Autofocus system for scanning microscopy having a volume image formation
US5619032A (en) 1995-01-18 1997-04-08 International Remote Imaging Systems, Inc. Method and apparatus for automatically selecting the best focal position from a plurality of focal positions for a focusing apparatus
JP4398020B2 (ja) * 1999-11-02 2010-01-13 オリンパス株式会社 多点自動焦点カメラ
JP4085297B2 (ja) * 2000-03-07 2008-05-14 東洋紡績株式会社 尿中有形成分分類装置
DE60117977D1 (de) * 2000-06-05 2006-05-11 Boston Scient Ltd Vorrichtungen zur behandlung von harninkontinenz
US6875973B2 (en) 2000-08-25 2005-04-05 Amnis Corporation Auto focus for a flow imaging system
US7538815B1 (en) * 2002-01-23 2009-05-26 Marena Systems Corporation Autofocus system and method using focus measure gradient
WO2004092781A2 (en) 2003-04-11 2004-10-28 Amnis Corporation Auto focus for a flow imaging system
JP5289768B2 (ja) * 2005-09-29 2013-09-11 オリンパス株式会社 焦点位置決定方法、焦点位置決定装置、微弱光検出装置及び微弱光検出方法
JP2007304059A (ja) * 2006-05-15 2007-11-22 Sysmex Corp 粒子画像分析装置
ES2599028T3 (es) 2008-03-21 2017-01-31 Abbott Point Of Care, Inc. Método y aparato para determinar una posición de enfoque de un dispositivo de representación de imágenes adaptado para representar por imágenes una muestra biológica
WO2010038230A1 (en) * 2008-10-02 2010-04-08 Focucell Ltd. Optical imaging based on viscoelastic focusing
WO2010129787A2 (en) * 2009-05-08 2010-11-11 The Johns Hopkins University Single molecule spectroscopy for analysis of cell-free nucleic acid biomarkers
US8831306B2 (en) * 2009-06-03 2014-09-09 Hitachi High-Technologies Corporation Flow type particle image analysis method and device
TWI413799B (zh) * 2009-06-05 2013-11-01 中原大學 The method of automatically looking for the focus position of the optical microscope
CN102782559B (zh) * 2009-12-31 2015-11-25 雅培照护点公司 用于快速聚焦形成生物样本的图像的方法及装置
US9001200B2 (en) * 2010-01-12 2015-04-07 Bio-Rad Laboratories, Inc. Cell characterization using multiple focus planes
KR20130131408A (ko) * 2010-12-21 2013-12-03 더 리전트 오브 더 유니버시티 오브 캘리포니아 모바일 장치 상의 콤팩트한 와이드­필드 형광 이미징
US10001622B2 (en) 2011-10-25 2018-06-19 Sanford Burnham Medical Research Institute Multifunction autofocus system and method for automated microscopy
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Also Published As

Publication number Publication date
US20170295314A1 (en) 2017-10-12
WO2016050767A1 (en) 2016-04-07
EP3202133B1 (en) 2018-11-21
US20170223262A1 (en) 2017-08-03
US9832366B2 (en) 2017-11-28
JP2017537337A (ja) 2017-12-14
EP3202133A1 (en) 2017-08-09

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