JP6605245B2 - Automatic analyzer - Google Patents

Description

  Embodiments described herein relate generally to an automatic analyzer.

  BACKGROUND ART An automatic analyzer for medical diagnosis is an apparatus for automatically and quantitatively measuring multiple items of serum components contained in a biological sample such as blood, and is widely used in clinical examinations.

  In an automatic analyzer equipped with a reagent storage, the reagent container is periodically replaced when the remaining amount of reagent in the reagent container stored in the reagent storage is low or when the reagent in the reagent container expires. Need to be done. In general, the reagent container is manually replaced by the user of the apparatus. When replacing the reagent container, the apparatus user recognizes the reagent container in which the reagent container to be replaced is stored and the position in the reagent container, and replaces the reagent container by itself.

  Therefore, the apparatus user may forget to replace the reagent container to be replaced. Moreover, even if the user of the apparatus misunderstands and intends to replace the reagent container to be replaced, there may be a situation in which the reagent container is not actually replaced.

JP 2008-32688 A JP 2000-321283 A

  An object of the embodiment is to provide an automatic analyzer capable of preventing omission of replacement such as failure to replace a reagent container to be replaced by a user or failure of replacement due to misunderstanding.

  According to the embodiment, the automatic analyzer includes a reagent storage and a first detection unit. The reagent store stores a plurality of reagent containers, and can move a reagent container to be replaced among the reagent containers to an exchange position. The first detection unit detects the presence or absence of the reagent container at the replacement position, and determines whether or not the reagent container to be replaced at the replacement position has been replaced with a new reagent container based on the detection result. .

FIG. 1 is a diagram illustrating a configuration of an automatic analyzer according to the first embodiment. FIG. 2 is an example of a cross-sectional view illustrating the configuration of the first reagent storage 15 in FIG. FIG. 3 is an example of a perspective view showing the configuration of the first reagent storage 15 in FIG. FIG. 4 is a flowchart showing the flow of the replacement work support according to the first embodiment. FIG. 5 is a diagram illustrating a configuration of an automatic analyzer according to a modification. FIG. 6 is an example of a perspective view illustrating the configuration of the first reagent storage 15 according to the modification. FIG. 7 is a flowchart showing a flow of replacement work support according to the modification. FIG. 8 is a diagram illustrating an example of the structure of a reagent storage according to another embodiment. FIG. 9 is a diagram illustrating an example of a configuration of an automatic analyzer according to another embodiment.

[First Embodiment]
Hereinafter, an automatic analyzer according to the present embodiment will be described with reference to the drawings.

  FIG. 1 is a diagram illustrating a configuration of an automatic analyzer according to the present embodiment. The automatic analyzer 1 includes an analysis mechanism 2, a drive unit 3, an analysis unit 4, a first notification unit 51, a second notification unit 52-1, a second notification unit 52-2, a display unit 6, and an input unit 7. , Storage unit 8, first detection units 90-1 and 90-2, second detection units 91-1 and 91-2, and system control unit 10.

  The analysis mechanism 2 is provided in the housing of the automatic analyzer 1. For example, as shown in FIG. 1, the analysis mechanism 2 includes a reaction disk 11, a sample disk 13, a first reagent container 15, a second reagent container 17, a sample arm 19-1, a sample probe 21-1, and a first reagent arm. 19-2, a first reagent probe 21-2, a second reagent arm 19-3, a second reagent probe 21-3, a stirring arm 23, a stirring bar 25, a photometric mechanism, and a cleaning mechanism 29 are mounted.

  The reaction disk 11 holds a plurality of reaction tubes 31 arranged in an annular shape. The reaction disk 11 is alternately rotated and stopped at predetermined time intervals. The reaction tube 31 is made of, for example, glass.

  The sample disk 13 is disposed in the vicinity of the reaction disk 11. The sample disk 13 holds a sample container 33 in which a specimen is accommodated. The sample disk 13 rotates so that the sample container 33 containing the sample to be dispensed is disposed at the sample inhaling position.

  The first reagent storage 15 is disposed inside the reaction disk 11. For example, as shown in FIG. 2, the first reagent storage 15 includes a cylindrical reagent storage main body 151 and a reagent container rack 152.

  The reagent storage body 151 covers the reagent container rack 152 with the side surface and the bottom surface as shown in FIG. For example, as shown in FIG. 3, the reagent storage main body 151 has a transparent first portion that is large enough to allow a first detection unit 90-1 to be described later to see through the first reagent container 35 at a predetermined portion. 1 detection window 153 is provided.

  For example, as shown in FIG. 3, the reagent storage body 151 has a second transparent portion having a size that allows a second detection unit 91-1 to be described later to see through the first reagent container 35 at a predetermined site. A detection window 154 is provided. As shown in FIG. 3, the predetermined portion indicates a portion located downstream in the direction (clockwise) in which a reagent container rack 152 described later is rotated as viewed from the position of the first detection window 153.

  The reagent container rack 152 accommodates a plurality of first reagent containers 35 arranged in a row in a circumferential shape. The reagent container rack 152 is rotated clockwise around the vertical line passing through the center of the first reagent storage 15 by the drive unit 3 under the control of the system control unit 10.

  As shown in FIG. 3, the first reagent container 35 has, for example, a barcode 351 indicating attribute information of the reagent container that the first reagent container 35 has on its back surface. The bar code 351 includes reagent attribute information such as a reagent name, lot number, reagent container type, and reagent expiration date. The first reagent container 35 is moved to a desired position by the rotation of the reagent container rack 152.

As shown in FIG. 3, the position 155 set inside the reagent storage body 151 and in the vicinity of the first detection window 153 is treated as an exchange position (hereinafter referred to as an exchange position 155). ). At the exchange position 155, the first reagent container 35 containing the first reagent that selectively reacts with the test item of the sample is exchanged. Further, at the replacement position 155, the replacement operation of the first reagent container 35 is detected by a first detection unit 90-1 described later.
Also, as shown in FIG. 3, a position 156 set inside the reagent storage body 151 and in the vicinity of the second detection window 154 is treated as a detection position (hereinafter referred to as a detection position 156). ). As shown in FIG. 1, the detection position 156 is set between the replacement position 155 and the first reagent suction position 157 where the first reagent probe 21-2 sucks the reagent from the first reagent container 35. The At the detection position 156, the barcode 351 attached to the first reagent container 35 is detected by a second detection unit 91-1, which will be described later.

  The second reagent storage 17 is disposed in the vicinity of the reaction disk 11. The second reagent storage 17 has the same structure as the first reagent storage 15 and includes a cylindrical reagent storage main body 171 and a reagent container rack 172.

  The reagent storage body 171 covers the reagent container rack 172 with the side surface and the bottom surface in the same manner as the reagent storage body 151. The reagent storage body 171 is a transparent first having a size that allows a first detection unit 90-2 (to be described later) to see through the second reagent container 37 in a predetermined portion like the reagent storage body 151. 1 detection window.

  The reagent storage body 171 has a transparent second detection that is large enough to allow a second detection unit 91-2, which will be described later, to see through the second reagent container 37 at a predetermined site in the same manner as the reagent storage body 151. Has a window. The predetermined portion indicates a portion located downstream in the direction (clockwise) in which a reagent container rack 172 described later rotates as seen from the position of the first detection window, as in the case of the reagent storage body 151.

  The reagent container rack 172 accommodates a plurality of second reagent containers 37 arranged in a row in a circumferential shape. The reagent container rack 172 is rotated clockwise around the vertical line passing through the center of the second reagent storage 17 by the drive unit 3 under the control of the system control unit 10.

  Similar to the first reagent container 35, the second reagent container 37 has, for example, a barcode indicating the attribute information of the reagent container that the second reagent container 37 has on its back surface. The second reagent container 37 moves to a desired position by the rotation of the reagent container rack 172.

Similarly to the reagent storage body 151, the position 175 set inside the reagent storage body 171 and in the vicinity of the first detection window is treated as an exchange position (hereinafter referred to as an exchange position 175). .)
At the exchange position 175, the second reagent container 37 that accommodates the second reagent paired with the first reagent is exchanged. Further, at the replacement position 175, the replacement operation of the second reagent container 37 is detected by a first detection unit 90-2 described later.

Similarly to the reagent storage body 151, the position 176 set inside the reagent storage body 171 and in the vicinity of the second detection window is treated as a detection position (hereinafter referred to as a detection position 176). ). As shown in FIG. 1, the detection position 176 is set between the replacement position 175 and the second reagent suction position 177 where the second reagent probe 21-3 sucks the reagent from the second reagent container 37. The
At the detection position 176, the barcode attached to the second reagent container 37 is detected by a second detection unit 91-2 described later.

  A sample arm 19-1 is disposed between the reaction disk 11 and the sample disk 13. A sample probe 21-1 is attached to the tip of the sample arm 19-1. The sample arm 19-1 supports the sample probe 21-1 so as to be movable up and down. The sample arm 19-1 supports the sample probe 21-1 so as to be rotatable along an arcuate rotation locus. The rotation trajectory of the sample probe 21-1 passes through the sample suction position on the sample disk 13 and the sample discharge position on the reaction disk 11.

  The sample probe 21-1 dispenses a sample every analysis cycle. The sample dispensing means that the specimen is sucked from the sample container 33 arranged at the sample suction position on the sample disk 13 and the specimen is put into the reaction tube 31 arranged at the specimen discharge position on the reaction disk 11. It is to discharge.

  A first reagent arm 19-2 is arranged in the vicinity of the outer periphery of the reaction disk 11. A first reagent probe 21-2 is attached to the tip of the first reagent arm 19-2. The first reagent arm 19-2 supports the first reagent probe 21-2 so as to be movable up and down. The first reagent arm 19-2 supports the first reagent probe 21-2 so as to be rotatable along an arcuate rotation locus. The rotation locus of the first reagent probe 21-2 passes through the first reagent suction position on the first reagent storage 15 and the first reagent discharge position on the reaction disk 11.

  The first reagent probe 21-2 dispenses the first reagent every analysis cycle. The dispensing of the first reagent means that the first reagent is sucked from the first reagent container 35 arranged at the first reagent suction position on the first reagent storage 15 and the first reagent is discharged on the reaction disk 11. The first reagent is discharged into the reaction tube 31 arranged at the position.

  Between the reaction disk 11 and the second reagent storage 17, a second reagent arm 19-3 is arranged. A second reagent probe 21-3 is attached to the tip of the second reagent arm 19-3. The second reagent arm 19-3 supports the second reagent probe 21-3 so as to be movable up and down. The second reagent arm 19-3 supports the second reagent probe 21-3 so as to be rotatable along an arcuate rotation locus. The turning locus of the second reagent probe 21-3 passes through the second reagent suction position on the second reagent storage 17 and the second reagent discharge position on the reaction disk 11.

  The second reagent probe 21-3 dispenses the second reagent every analysis cycle. The dispensing of the second reagent means that the second reagent is sucked from the second reagent container 37 arranged at the second reagent suction position on the second reagent storage 17 and the second reagent is discharged on the reaction disk 11. The second reagent is discharged into the reaction tube 31 arranged at the position.

  A stirring arm 23 is disposed near the outer periphery of the reaction disk 11. A stirring bar 25 is attached to the tip of the stirring arm 23. The stirring arm 23 supports the stirring bar 25 so as to be movable up and down. Further, the stirring arm 23 supports the stirring bar 25 so as to be rotatable along an arcuate rotation locus. The stirrer 25 stirs the mixed solution of the specimen and the first reagent in the reaction tube 31 disposed at the stirring position on the reaction disk 11 or the mixed liquid of the specimen, the first reagent, and the second reagent. Hereinafter, these mixed solutions are referred to as reaction solutions.

  As shown in FIG. 1, a photometric mechanism (not shown) is provided in the vicinity of the reaction disk 11. The photometric mechanism operates according to control by the system control unit 10. Specifically, the photometric mechanism has a light source (not shown) and a photodetector. The light emitted from the light source passes through the reaction solution in the reaction tube 31 and is detected by a photodetector. The photodetector generates data having a measurement value corresponding to the detected light intensity (hereinafter referred to as photometry data). The generated photometric data is supplied to the analysis unit 4.

  A cleaning mechanism 29 is provided on the outer periphery of the reaction disk 11. The cleaning mechanism 29 operates according to control by the drive unit 3. Specifically, the cleaning mechanism 29 is provided with a cleaning nozzle and a drying nozzle. The cleaning mechanism 29 cleans the reaction tube 31 at the cleaning position of the reaction disk 11 with a cleaning nozzle and dries it with a drying nozzle.

  The drive unit 3 has a gear, a motor, and the like (not shown). The drive unit 3 rotates, for example, the reagent container rack 152 according to the control of the system control unit 10 and moves the first reagent container 35 to the replacement position 155 or the like. The drive unit 3 rotates, for example, the reagent container rack 172 according to the control of the system control unit 10 and moves the second reagent container 37 to the replacement position 175 or the like.

  The analysis unit 4 is realized as a processor having a memory, for example. The analysis unit 4 reads out the operation program from the storage unit 8 and calculates measurement item values according to the operation program. The analysis unit 4 calculates a measurement item value related to the colorimetric measurement for the reaction solution based on the photometric data. Specifically, the analysis unit 4 calculates the absorbance of the reaction solution based on the photometric data, and calculates the measurement item value based on the calculated absorbance. The analysis unit 4 links information such as the calculated measurement item value to the system control unit 10.

  The 1st alerting | reporting part 51 is provided in the side surface of the automatic analyzer 1 as shown, for example in FIG. 1, and has LED and a speaker, or any one. The 1st alerting | reporting part 51 lights LED, for example under control of the system control part 10. FIG. The first notification unit 51 emits a warning sound from, for example, a speaker under the control of the system control unit 10. For example, when the automatic analyzer 1 has a reagent container to be exchanged instructed by the apparatus user, the first notification unit 51 notifies the apparatus user by turning on the LED. For example, if the reagent container exchanged by the device user is incorrect, the first notification unit 51 notifies the device user by issuing a warning sound.

  The 2nd alerting | reporting part 52-1 is installed in the vicinity of the exchange position 155, for example, has LED. The 2nd alerting | reporting part 52-1 shows the status of replacement | exchange work by taking any state of a lighting state, a blinking state, or a light extinction state under control of the system control part 10, for example. The second notification unit 52-1 is turned on when, for example, the reagent container to be replaced in the first reagent storage 15 reaches the replacement position 155. The second notification unit 52-1 blinks, for example, during replacement work. The second notification unit 52-1 is turned off after the replacement, for example.

  The 2nd alerting | reporting part 52-2 is installed in the vicinity of the exchange position 175, for example, has LED. The 2nd alerting | reporting part 52-2 shows the status of exchange work by taking any state of a lighting state, a blinking state, or a light extinction state under control of the system control part 10, for example. The second notification unit 52-2 is turned on when, for example, the reagent container to be replaced in the second reagent storage 17 reaches the replacement position 175. The second notification unit 52-2 blinks, for example, during replacement work. For example, the second notification unit 52-2 is turned off after the replacement.

  The display unit 6 includes display devices such as a CRT display, a liquid crystal display, an organic EL display, and a plasma display. The display unit 6 is controlled by the system control unit 10, for example, through the display device, information indicating the position of the reagent container to be replaced, the measurement item value calculated by the analysis unit 4, and a first detection unit 90 described later. Information indicating that the replacement operation detected by -1 or 90-2 has been performed, and whether or not the replaced reagent container detected by the second detection unit 91-1 or 91-2 described later is correct The information etc. which show are displayed.

  The input unit 7 accepts various commands or / and information input via an input device from an operator. As the input device, a pointing device such as a mouse or a trackball, a selection device such as a switch button, or an input device such as a keyboard or a touch screen can be used as appropriate. The input unit 7 links the received various commands and information input to the system control unit 10.

  The storage unit 8 stores the operation program of the automatic analyzer 1 and the analysis unit 4, the replacement list information of reagent containers to be exchanged given in advance, the measurement item value calculated by the analysis unit 4, and a first to be described later. Detection information detected by the detection units 90-1 and 90-2, detection information detected by second detection units 91-1 and 91-2, which will be described later, and the like are stored. The replacement list information includes reagent attribute information for each reagent container to be replaced.

  The first detection unit 90-1 includes, for example, an optical sensor and an exchange determination unit. An optical sensor has, for example, a light projecting unit and a light receiving unit. The light projecting unit projects light onto a detection target, the reflected light with respect to the input light is detected by the light receiving unit, and the intensity of the detected reflected light is determined. This is a reflection type photosensor that outputs an electrical signal. The first detection unit 90-1 is provided outside the first reagent storage 15 so that light can be projected to the first reagent container 35 located at the replacement position 155 with an optical sensor through the first detection window 153, for example. .

  The optical sensor of the first detection unit 90-1 starts light projection when receiving an instruction to start replacement work supplied from the system control unit 10. Hereinafter, an electrical signal output from the optical sensor is referred to as a light detection signal. The light detection signal is supplied to the replacement determination unit of the first detection unit 90-1. The instruction to start the replacement work supplied from the system control unit 10 may be given to the optical sensor of the first detection unit 90-1 via the replacement determination unit of the first detection unit 90-1.

  The replacement determination unit of the first detection unit 90-1 is realized as a processor having a memory and a storage unit, for example. The replacement determination unit of the first detection unit 90-1 stores an operation program related to the replacement determination function in the storage unit in advance. The replacement determination unit of the first detection unit 90-1 recognizes the presence or absence of the reagent container at the replacement position based on the change in the intensity of the light detection signal supplied from the optical sensor, and determines whether the reagent container has been replaced. judge. The replacement determination unit of the first detection unit 90-1 notifies the system control unit 10 that the replacement operation of the reagent container to be replaced has been performed at the replacement position 155.

  In the replacement determination unit of the first detection unit 90-1, for example, a threshold value I is set in advance for the intensity of the light detection signal. The replacement determination unit of the first detection unit 90-1 recognizes that the reagent container to be replaced has been removed when the intensity of the supplied light detection signal changes from a state of I or higher to a state lower than I. . The replacement determination unit of the first detection unit 90-1 recognizes that a new reagent container has been attached when the intensity of the supplied light detection signal changes from a state smaller than I to a state higher than I. The replacement determination unit of the first detection unit 90-1 continuously recognizes the removal operation of the reagent container to be replaced and the attachment operation of a new reagent container within a preset time in the order of removal and attachment. If it is, it is determined that one replacement operation has been performed. If the replacement determination unit of the first detection unit 90-1 does not detect the attachment / detachment operation within a preset time, it notifies the system control unit 10 that a timeout has occurred.

  The replacement determination unit of the first detection unit 90-1 receives a notification from the system control unit 10 that all replacement of reagent containers to be replaced included in the replacement list information has been completed. Upon receiving this notification, the replacement determination unit of the first detection unit 90-1 ends the replacement determination operation.

  The first detection unit 90-2 includes, for example, an optical sensor and an exchange determination unit. The first detection unit 90-2 is provided outside the second reagent container 17 so that light can be projected to the second reagent container 37 located at the replacement position 175 with a photosensor, for example, through the first detection window. In addition, the structure and operation | movement of the 1st detection part 90-2 are the same as that of the 1st detection part 90-1.

  The second detection unit 91-1 includes, for example, a barcode reader and an erroneous replacement determination unit. For example, as shown in FIG. 3, the second detection unit 91-1 is a barcode attached to the back surface of the first reagent container 35 located at the detection position 156 by a barcode reader through the second detection window 154. Is provided outside the first reagent storage 15.

  The barcode reader of the second detection unit 91-1 starts reading with an instruction from the system control unit 10 to start an erroneous replacement detection process. The barcode reader of the second detection unit 91-1 reads the barcode attached to the first reagent container 35. The barcode reader of the second detection unit 91-1 supplies the read reagent attribute information to the erroneous replacement determination unit of the second detection unit 91-1. Note that the instruction to start the erroneous replacement detection process supplied from the system control unit 10 may be given to the barcode reader of the second detection unit 91-1 via the erroneous replacement determination unit of the second detection unit 91-1. Good.

  The erroneous replacement determination unit of the second detection unit 91-1 is realized as a processor having a memory and a storage unit, for example. The erroneous replacement determination unit of the second detection unit 91-1 stores an operation program related to the erroneous replacement determination function in the storage unit in advance. The erroneous replacement determination unit of the second detection unit 91-1 receives from the system control unit 10 the replacement list information of the reagent container to be replaced that is stored in the storage unit 8. The erroneous replacement determination unit of the second detection unit 91-1 includes the reagent attribute information supplied from the barcode reader of the second detection unit 91-1 and the reagent container to be replaced received from the system control unit 10. The attribute information included in the replacement list information is compared to determine whether or not the replaced reagent container is correct. The erroneous replacement determination unit of the second detection unit 91-1 notifies the system control unit 10 of the determination result as to whether or not the replaced reagent container is correct.

  The erroneous replacement determination unit of the second detection unit 91-1 receives a notification from the system control unit 10 that all replacement of reagent containers to be replaced included in the replacement list information has been completed. The erroneous replacement determination unit of the second detection unit 91-1 receives this notification and ends the erroneous replacement determination operation.

  The second detection unit 91-2 includes, for example, a barcode reader and an erroneous replacement determination unit. Similar to the second detection unit 91-1 in the first reagent storage 15, the second detection unit 91-2 is, for example, a second reagent container located at the detection position 176 with a barcode reader over the second detection window. It is provided outside the second reagent storage 17 so that the barcode attached to the rear surface portion of 37 can be read. In addition, the structure and operation | movement of the 2nd detection part 91-2 are the same as that of the 2nd detection part 91-1.

  The system control unit 10 functions as the center of the automatic analyzer 1. The system control unit 10 is realized as a processor having a memory, for example.

  The system control unit 10 reads the operation program from the storage unit 8, and according to the operation program, the drive unit 3, the first notification unit 51, the second notification unit 52-1, the second notification unit 52-2, the first The detection units 90-1 and 90-2 and the second detection units 91-1 and 91-2 are controlled. The system control unit 10 calculates various information related to automatic analysis based on various information acquired from the analysis mechanism 2.

  The system control unit 10 includes a drive unit 3, a first notification unit 51, a second notification unit 52-1, and a second notification unit 52 based on various commands or / and information input linked from the input unit 7. -2, controls the first detection units 90-1 and 90-2, and the second detection units 91-1 and 91-2.

  Specifically, when the replacement operation start instruction is input to the input unit 7, the system control unit 10 controls the driving unit 3 to rotate the reagent container rack 152 to change the reagent container to be replaced. Move to exchange position 155. When the replacement work start instruction is input to the input unit 7, the system control unit 10 controls the drive unit 3 to rotate the reagent container rack 172 and move the reagent container to be replaced to the replacement position 175. Let

  When the movement of the reagent container to be replaced is completed, the system control unit 10 starts detecting the replacement operation for the replacement determination unit of the first detection unit 90-1 or the replacement determination unit of the first detection unit 90-2. Instruct. The system control unit 10 receives a notification that the replacement operation has been performed from the replacement determination unit of the first detection unit 90-1 or the replacement determination unit of the first detection unit 90-2.

  When the system control unit 10 receives a notification that the replacement operation has been performed from the first detection unit 90-1, the system control unit 10 controls, for example, the drive unit 3 to rotate the reagent container rack 152 and replace it. A new reagent container is moved from the replacement position 155 to the detection position 156. When the system control unit 10 receives a notification that the replacement operation has been performed from the first detection unit 90-2, for example, the system control unit 10 controls the drive unit 3 to rotate the reagent container rack 172 and replace it. A new reagent container is moved from the replacement position 175 to the detection position 176.

  When the movement of the replaced new reagent container is completed, the system control unit 10 instructs the second detection unit 91-1 or the second detection unit 91-2 to start the erroneous replacement operation detection. The system control unit 10 receives notification of a determination result as to whether or not the replaced reagent container is correct from the second detection unit 91-1 or the second detection unit 91-2.

  When the system control unit 10 receives a timeout notification from the first detection unit 90-1 or the first detection unit 90-2, for example, the system control unit 10 controls the first notification unit 51 to urge the user to replace the device. Give a warning to that effect.

  When the system control unit 10 receives a notification that an incorrect replacement has been performed from the second detection unit 91-1 or the second detection unit 91-2, for example, the system control unit 10 controls the display unit 6 to display a warning screen. Etc. are displayed. Further, the system control unit 10 controls the first notification unit 51, for example, and notifies the user of the device that there has been an erroneous replacement by making a sound or the like.

  When the system control unit 10 receives a notification from the second detection unit 91-1 that the correct replacement has been performed, the system control unit 10 increases the value of the count variable n by 1, and aims the reagent container to be replaced next. shift.

  If the system control unit 10 determines that all replacement processing has been completed, the system control unit 10 controls, for example, the display unit 6 and displays a replacement end screen. If the system control unit 10 determines that all the replacement processes have been completed, the system control unit 10 controls the first notification unit 51 to notify the apparatus user that the replacement has been completed by, for example, generating a sound. If the system control unit 10 determines that all the replacement processes have been completed, the system control unit 10 controls the second notification unit, for example, and notifies the apparatus user that the replacement has been completed by turning off the LED. If the system control unit 10 determines that all the replacement processes have been completed, the system controller 10 determines that the replacement has been completed, the replacement determination unit of the first detection units 90-1 and 90-2, and the second detection units 91-1 and 91-2. Are instructed to the erroneous replacement determination unit.

  Next, the operation of the first embodiment will be described. FIG. 4 is an example of a flowchart of processing performed by the system control unit 10. Hereinafter, the flow of replacement work in the first reagent storage 15 will be described using the example of the flowchart shown in FIG.

  First, the system control unit 10 receives an instruction to start the exchange operation detection together with information such as the number of reagent containers to be exchanged (for example, N) designated by the apparatus user via the input unit 7. At the same time, the system control unit 10 saves the received information as exchange list information in the storage unit 8 (step SA1).

  The system control unit 10 reads the exchange list information stored in step SA1 from the storage unit 8, and delivers it to the erroneous replacement determination unit of the second detection unit 91-1. At the same time, based on this exchange list information, the system control unit 10 sets initial parameters, for example, by setting the initial value of the count variable n to 1, and the number of reagent containers to be processed as N (step SA2). The system control unit 10 controls the drive unit 3 to rotate the reagent container rack 152 and move the reagent container to be replaced to the replacement position 155 (step SA3).

  Thereafter, the system control unit 10 instructs the optical sensor of the first detection unit 90-1 to start the replacement operation detection (step SA4). The system control unit 10 waits until a notification indicating that the replacement operation has been performed or a timeout has been received from the replacement determination unit of the first detection unit 90-1 (step SA5).

  When the system control unit 10 receives a notification that the replacement operation has been performed from the replacement determination unit of the first detection unit 90-1 (Yes in step SA5), the system control unit 10 controls the driving unit 3 to thereby change the reagent container rack. 152 is rotated to move the replaced new reagent container from the replacement position 155 to the detection position 156 (step SA6).

  When the system control unit 10 receives a notification of timeout from the replacement determination unit of the first detection unit 90-1 (No in step SA5), for example, the system control unit 10 controls the first notification unit 51 to notify the user of the apparatus. Give a warning to encourage replacement. At the same time as the warning, the system control unit 10 sends a temporary suspension to the replacement determination unit of the first detection units 90-1 and 90-2 and the erroneous replacement determination unit of the second detection units 91-1 and 91-2. An instruction is given (step SA7). After step SA7, the system control unit 10 ends the process. Note that the system control unit 10 may restart the process from step SA4 when receiving an instruction to restart replacement from the apparatus user via the input unit 7.

  In step SA6, when the movement of the replaced new reagent container from the replacement position 155 to the detection position 156 is completed, the system control unit 10 performs an erroneous replacement detection process on the barcode reader of the second detection unit 91-1. The start is instructed (step SA8).

  The system control unit 10 waits until receiving a determination result notification indicating whether or not the reagent container replaced by the second detection unit 91-1 is correct (step SA9).

  When the determination result notified from the erroneous replacement determination unit of the second detection unit 91-1 indicates that the exchanged reagent container is not correct (No in step SA9), the system control unit 10 displays, for example, The unit 6 is controlled and a warning screen is displayed. In addition, the system control unit 10 controls the first notification unit 51 to notify the user of the device that there has been an erroneous replacement by making a sound or the like. Thereafter, the system control unit 10 starts the control in step SA3 again with the count variable n remaining the same (step SA11).

  When the determination result notified from the erroneous replacement determination unit of the second detection unit 91-1 indicates that the exchanged reagent container is correct (Yes in step SA9), the system control unit 10 counts the variable n. Is increased by 1 and the aim is shifted to the reagent container to be replaced next (step SA10).

  After step SA10, the system control unit 10 determines whether or not the current value of the count variable n is larger than the number N of reagent containers to be processed (step SA12). The system control unit 10 performs the control of step SA3 again when n ≦ N. If n> N (Yes in step SA12), the system control unit 10 determines that all replacement processes have been completed. In this case, for example, the system control unit 10 controls the display unit 6 to display an exchange end screen. In addition, the system control unit 10 controls the first notification unit 51 to notify the apparatus user that the replacement has been completed by making a sound or the like. Further, the system control unit 10 controls the second notification unit to notify the apparatus user or the like that the replacement has been completed by turning off the LED. In addition, the system control unit 10 notifies the end of replacement to the replacement determination unit of the first detection units 90-1 and 90-2 and the erroneous replacement determination unit of the second detection units 91-1 and 91-2, respectively ( Step SA13).

  The flow of replacement work in the second reagent storage 17 is the same as the flow of replacement work in the first reagent storage 15.

  According to the first embodiment, the first detection unit 90-1 detects whether or not the reagent container to be replaced has been replaced at the replacement position 155 provided in the reagent storage body 151. . In addition, the first detection unit 90-2 detects whether or not the reagent container to be replaced has been replaced at the replacement position 175 provided in the reagent storage body 171. Thereby, the detection of the exchange operation can be performed without the intervention of the user of the apparatus.

  Therefore, according to the automatic analyzer according to the present embodiment, it is possible to prevent replacement leakage such as failure to replace the reagent container to be replaced by the user or failure of replacement due to misunderstanding.

  Further, according to the first embodiment, the system control unit 10 indicates that the replacement of the reagent container to be replaced has been performed, the first notification unit 51, the second notification units 52-1 and 52-. 2 is notified to the outside. As a result, the device user or the like can recognize that the replacement has been performed reliably.

  Further, according to the first embodiment, the first detection units 90-1 and 90-2 notify the system control unit 10 that the reagent container to be replaced has been replaced. As a result, the system control unit 10 that has received the notification can grasp the status of the replacement work by the device user and manage the replacement omission.

  Further, according to the first embodiment, the system control unit 10 receives the notification that the replacement of the reagent container to be replaced has been performed from the first detection unit 90-1 or 90-2, and is driven. The unit 3 is controlled to move the reagent container to be replaced next to the replacement position 155 or 175 among the reagent containers included in the replacement list information related to the reagent container to be replaced specified in advance. Thereby, it becomes possible to carry out the replacement work of the reagent container reliably and efficiently by the user of the apparatus.

  Further, according to the first embodiment, the second detection units 91-1 and 91-2 are exchanged by comparing the detected new reagent container information with the exchange list information given in advance. It is determined whether or not the new reagent container is correct. As a result, the user of the apparatus can perform the reagent container replacement operation without error.

  According to the first embodiment, the detection position between the second detection unit 91-1 and the position at which the second detection unit 91-1 reaches the first reagent suction position 157 from the replacement position 155 in the rotation direction (clockwise). 156 is installed in the vicinity. Further, according to the first embodiment, the detection position between the second detection unit 91-2 and the position where the second detection unit 91-2 reaches the second reagent suction position 177 in the rotation direction (clockwise) from the replacement position 175. 176. As a result, it is possible to detect erroneous replacement of the reagent container at the timing before the reagent inhalation.

  Further, according to the first embodiment, the first notification unit 51 and the second notification units 52-1 and 52-2 are controlled to determine whether or not the replaced new reagent container is correct. To inform the outside. As a result, it is possible to discover during the replacement work that the user of the apparatus has replaced the wrong reagent container.

  Further, according to the first embodiment, the first detection units 90-1 and 90-2 notify the system control unit 10 that the reagent container to be replaced has been replaced. In addition, the second detection units 91-1 and 91-2 notify the system control unit 10 whether or not the new reagent container to be replaced is correct. As a result, the system control unit 10 that has received the notification can grasp the status of the replacement operation by the user of the apparatus, and manage the replacement leakage and replacement error of the reagent container.

  Further, according to the first embodiment, the system control unit 10 manages the replacement list information regarding the reagent container to be replaced specified in advance, and is replaced by the first detection unit 90-1 or 90-2. When it is notified that the reagent container to be replaced has been notified, the drive unit 3 is controlled so that the reagent container that is included in the replacement list information and that is to be replaced next moves to the replacement position 155 or 175. In addition, when the system control unit 10 is notified by the second detection unit 91-1 or 91-2 that the new reagent container replaced is incorrect, the reagent container installed in error is replaced again. The drive unit 3 is controlled to move to the position 155 or 175. As a result, when the user of the apparatus replaces the reagent container to be replaced with an incorrect reagent container, the replacement work can be performed again reliably and quickly.

[Modification]
In the first embodiment, the case where the reagent container replacement positions 155 and 175 and the detection positions 156 and 176 are different from each other has been described. In the modified example, a case where the reagent container replacement position 155 and the detection position 156 and the replacement position 175 and the detection position 176 are the same will be described.

  FIG. 5 is a diagram illustrating a configuration of an automatic analyzer according to a modification. The automatic analyzer 1A includes an analysis mechanism 2A, a drive unit 3, an analysis unit 4, a first notification unit 51, a second notification unit 52-1, a second notification unit 52-2, a display unit 6, and an input unit 7. , Storage unit 8, first detection units 90-1, 90-2, second detection units 91-1, 91-2, and system control unit 10A.

  The analysis mechanism 2A is provided in the housing of the automatic analyzer 1A. For example, as shown in FIG. 5, the analysis mechanism 2A includes a reaction disk 11, a sample disk 13, a first reagent container 15A, a second reagent container 17A, a sample arm 19-1, a sample probe 21-1, and a first reagent arm. 19-2, a first reagent probe 21-2, a second reagent arm 19-3, a second reagent probe 21-3, a stirring arm 23, a stirring bar 25, a photometric mechanism, and a cleaning mechanism 29 are mounted.

  Reaction disk 11, sample disk 13, sample arm 19-1, sample probe 21-1, first reagent arm 19-2, first reagent probe 21-2, second reagent arm 19-3, second reagent probe 21- 3. The configuration and functions of the stirring arm 23, the stirring bar 25, the photometry mechanism, and the cleaning mechanism 29 are the same as those in the first embodiment.

  The first reagent storage 15 </ b> A is disposed inside the reaction disk 11. The first reagent storage 15 </ b> A includes a cylindrical reagent storage main body 151 </ b> A and a reagent container rack 152, similarly to the first reagent storage 15 of the first embodiment.

  The reagent storage body 151A covers the reagent container rack 152 with the side surface and the bottom surface in the same manner as the first reagent storage 15 of the first embodiment. For example, as shown in FIG. 6, the reagent storage body 151 </ b> A can be seen through the first reagent container 35 by a first detection unit 90-1 </ b> A and a second detection unit 91-1, which will be described later, at a predetermined part. A transparent first detection window 153 having a certain size is provided.

  The configurations and functions of the reagent container rack 152 and the first reagent container 35 are the same as those in the first embodiment.

  Also, as shown in FIG. 6, a position 155A set inside the reagent storage body 151 and in the vicinity of the first detection window 153 is treated as an exchange position (hereinafter referred to as an exchange position 155A). ).

At the replacement position 155A, the first reagent container 35 is replaced. Further, at the replacement position 155A, the replacement operation of the first reagent container 35 is detected by a first detection unit 90-1 described later.
Further, at the replacement position 155A, the barcode 351 attached to the first reagent container 35 is detected by a second detection unit 91-1, which will be described later. That is, the position corresponding to the detection position 156 in the first embodiment is the same as the replacement position 155A.

  The second reagent storage 17 </ b> A is disposed in the vicinity of the reaction disk 11. The second reagent store 17 has the same structure as the first reagent store 15A, and includes a cylindrical reagent store main body 171A and a reagent container rack 172.

The configuration and functions of the reagent storage body 171A are the same as those of the reagent storage body 151A.
The configurations and functions of the reagent container rack 172 and the second reagent container 37 are the same as those in the first embodiment.

  Drive unit 3, analysis unit 4, first notification unit 51, second notification unit 52-1, second notification unit 52-2, display unit 6, input unit 7, storage unit 8, first detection unit The configurations and functions of 90-1 and 90-2 and the second detection units 91-1 and 91-2 are the same as those in the first embodiment.

The system control unit 10 according to the first embodiment controls the driving unit 3 when receiving a notification that the replacement operation has been performed from the first detection unit 90-1 or the first detection unit 90-2. Then, the reagent container rack 152 is rotated, and the replaced new reagent container is moved from the replacement position 155 to the detection position 156, and then the second detection unit 91-1 or the second detection unit 91-2. Is instructed to start erroneous replacement operation detection. The system control unit 10A is different from the system control unit 10 in this respect.
That is, when the system control unit 10A receives a notification that the replacement operation has been performed from the first detection unit 90-1 or the first detection unit 90-2, the replaced new reagent container is moved. First, the second detection unit 91-1 or the second detection unit 91-2 is instructed to start detection of an erroneous replacement operation. Other functions of the system control unit 10A are the same as those of the system control unit 10 according to the first embodiment.

  Next, the operation of the modification will be described. FIG. 7 is an example of a flowchart of processing performed by the system control unit 10A. Hereinafter, the flow of replacement work in the first reagent storage 15 will be described using the example of the flowchart shown in FIG.

  Steps SA1 to SA5 are the same as those in the first embodiment.

When the system control unit 10A receives a notification that the replacement operation has been performed from the replacement determination unit of the first detection unit 90-1 (Yes in step SA5), the barcode of the second detection unit 91-1 The reader is instructed to start erroneous exchange detection processing (step SB1).
Steps SA7 and SA9 are the same as in the first embodiment.

  When the determination result notified from the erroneous replacement determination unit of the second detection unit 91-1 indicates that the exchanged reagent container is not correct (No in step SA9), the system control unit 10A displays, for example, a display The unit 6 is controlled and a warning screen is displayed. Further, the system control unit 10A controls the first notification unit 51 to notify the device user and the like that there has been an erroneous replacement by making a sound or the like. Thereafter, the system control unit 10A starts the control in step SA4 again (step SB2).

Step SA10, step SA12, and step SA13 are the same as in the first embodiment.
The flow of replacement work in the second reagent storage 17A is the same as the flow of replacement work in the first reagent storage 15A.

  According to the modification, unlike the first embodiment, the detection by the first detection unit 90-1 and the detection by the second detection unit 91-1 at the same replacement position 155A in the first reagent storage 15A. Is performed continuously. In addition, at the same replacement position 175A in the second reagent storage 17A, detection by the first detection unit 90-2 and detection by the second detection unit 91-2 are continuously performed. Thereby, it is possible to reduce the number of times of rotation control in the system control unit 10A. At the same time, it is possible to shorten the time for replacement work.

[Other Embodiments]
The present invention is not limited to the above embodiment. For example, in the first embodiment, one automatic analyzer is assumed, but a plurality of automatic analyzers may be assumed. In this case, for example, the first notification unit 51 is installed for each automatic analyzer. Thus, the device user can recognize which automatic analyzer has the reagent container to be replaced. Therefore, the apparatus user can efficiently replace the reagent container to be replaced across a plurality of automatic analyzers.

  In the first embodiment, it is assumed that two reagent containers are mounted on one automatic analyzer, but one reagent container may be mounted on one automatic analyzer. Two or more reagent storages may be mounted. In this case, for example, when there are three or more reagent storages to be replaced, the second notification unit 52-1 or 52-2 is installed for each reagent storage. Thereby, the apparatus user can recognize which reagent container has the reagent container to be replaced. Therefore, the apparatus user can efficiently exchange the reagent container to be exchanged across a plurality of reagent containers.

  Further, the first reagent storage 15 and the second reagent storage 17 of the first embodiment are provided with the reagent container installation place only on one circumference in one reagent storage, but the present invention is not limited to this. For example, as shown in FIG. 8, one reagent store may have a double region of an outer peripheral region 18-1 and an inner peripheral region 18-2, and a plurality of reagent container installation locations may be provided. That is, for example, an exchange position 158-1 is provided in the outer peripheral region 18-1. At the replacement position 158-1, for example, the first detector 90-3 detects the reagent container replacement operation. Further, at the replacement position 158-1, for example, the second detection unit 91-3 detects the barcode attached to the reagent container. In addition, a second notification unit 52-3 is installed in the vicinity of the exchange position 158-1a. Further, in the inner peripheral region 18-2, for example, an exchange position 158-2 is provided. At the replacement position 158-2, for example, the first container 90-4 detects the reagent container replacement operation. Further, at the replacement position 158-2, for example, the second detection unit 91-4 detects the barcode attached to the reagent container. In addition, a second notification unit 52-4 is installed in the vicinity of the exchange position 158-2. In addition, the 1st detection part 90-3 and the 2nd detection part 91-3, the 1st detection part 90-4, and the 2nd detection part 91-4 may be provided in the same position. Moreover, the position of the 1st detection part 90-3 and the 2nd detection part 91-3 or the 1st detection part 90-4 and the 2nd detection part 91-4 may be provided in a separate position. Moreover, you may provide an installation area | region 3 or more times.

  In the first embodiment, as shown in FIGS. 1 and 5, the first detection unit 90-1 and the second detection unit 91-1 are provided outside the reagent storage main unit 151 and the first detection unit 90-1 is provided. The method for detecting the reagent container 35 or the method for detecting the second reagent container 37 by providing the first detection unit 90-2 and the second detection unit 91-2 outside the reagent storage body 171 has been described. The method is not limited to this.

  For example, a first detector 90-1 may be provided on the inner peripheral surface of the reagent storage body 151 to detect the presence or absence of a reagent container and determine whether or not an exchange operation has been performed. Also, the second detector 91-1 is provided on the inner peripheral surface of the reagent storage body 151, reads the barcode of the replaced reagent container, and determines whether or not the replaced reagent container is correct. You may make it determine. Alternatively, the first detector 90-2 may be provided on the inner peripheral surface of the reagent storage body 171 to detect the presence or absence of a reagent container and determine whether or not an exchange operation has been performed. In addition, a second detector 91-2 is provided on the inner peripheral surface of the reagent storage body 171 to read the barcode of the replaced reagent container, and to check whether or not the replaced reagent container is correct. You may make it determine.

  Further, after Yes in step SA12 in the flowchart of FIG. 4 according to the first embodiment or the flowchart of FIG. 7 according to the modification, the system control unit 10 or 10A determines that all the replacement processes have been completed, and detects them. The process is terminated, but is not limited to this.

  Specifically, after Yes in step SA12 and before step SA13 in the flowchart of FIG. 4 according to the first embodiment, or after Yes in step SA12 and before step SA13 in the flowchart of FIG. 7 according to the modification. In addition, a detection process for performing a simultaneous check on whether or not the replaced reagent container is correct may be added. In other words, the recheck is performed after all the replacement of the reagent containers to be exchanged included in the exchange list information is completed. This makes it possible to perform a more reliable replacement operation.

In the first embodiment, whether or not a new reagent container after replacement has been replaced is determined only by detection by the first detection unit. However, the present invention is not limited to this.
For example, you may add the detection result of the reagent container used as the exchange object after exchange to the determination conditions that one exchange operation was performed. Specifically, in the automatic analyzer 1 of FIG. 1, a third detection unit is installed at a predetermined position near the reaction disk 11. The third detection unit includes, for example, a barcode reader and an exchange determination unit. When the reagent container removed at the time of replacement is placed at a predetermined position, the barcode reader reads the attribute information of the reagent included in the barcode attached to the back surface of the reagent container. The barcode reader supplies the read reagent attribute information to the exchange determination unit. The exchange determination unit compares the attribute information of the reagent supplied from the barcode reader with the attribute information included in the exchange list information given in advance. The replacement determination unit determines whether or not the read reagent attribute information matches the reagent attribute information of the reagent container to be replaced included in the replacement list information. The replacement determination unit notifies the determination result to the system control unit.
The system control unit, for example, after Yes in step SA5 in FIG. 4 and before step SA6, when the read reagent attribute information matches the reagent attribute information of the reagent container to be exchanged included in the exchange list information Then, the processes after step SA6 are performed.

  In addition, the detection means used in the first detection units 90-1 and 90-2 and the second detection units 91-1 and 91-2 in the first embodiment may be of any method as long as the same purpose can be achieved. Absent. For example, an RFID (Radio frequency IDentification), a weight sensor, and other sensors using image recognition technology may be substituted.

  Further, the display unit 6 may be combined with a function for displaying a list of reagent containers that need to be replaced so that the user of the apparatus can easily instruct replacement of a plurality of reagent containers. For example, the system control unit 10 sets threshold values for the number of remaining uses, the remaining amount, and the like for each reagent container, and displays a list of comparison determination results with the threshold values on the display unit 6.

  In the first embodiment, the case where the first detection unit includes the replacement determination unit and the second detection unit includes the erroneous replacement determination unit has been described. For example, as illustrated in FIG. The determination unit and the erroneous replacement determination unit may be mounted in the system control unit 10B. At this time, the first detection units 90-1B and 90-2B have only optical sensors. The second detection units 91-1B and 91-2B have only a barcode reader. On the other hand, the system control unit 10 </ b> B includes a replacement determination unit 101 and an erroneous replacement determination unit 102.

  In this case, the replacement determination unit 101 recognizes the presence or absence of the reagent container at the replacement position based on the change in the intensity of the light detection signal supplied from the optical sensor of the first detection unit 90-1B or 90-2B, It is determined whether or not the reagent container has been replaced. The erroneous replacement determination unit 102 includes the attribute information of the reagent supplied from the barcode reader of the second detection unit 91-1B or 91-2B and the attribute information included in the replacement list information of the reagent container to be replaced. A comparison is made to determine whether the exchanged reagent container is correct.

  The term “processor” used in the above description is, for example, a CPU (central processing unit), a GPU (Graphics Processing Unit), or an application specific integrated circuit (ASIC)), a programmable logic device (for example, It means a circuit such as a simple programmable logic device (SPLD), a complex programmable logic device (CPLD), and a field programmable gate array (FPGA). The processor implements a function by reading and executing a program stored in the storage unit 8. Instead of storing the operation program of the analysis unit 4, the system control unit 10, 10A, or 10B in the storage circuit, each operation program may be directly incorporated in the circuit of each processor. In this case, the processor realizes the function by reading and executing the program incorporated in the circuit. Each processor of the present embodiment is not limited to being configured as a single circuit for each processor, but is configured as a single processor by combining a plurality of independent circuits, and includes a system control function, a replacement determination function, an error You may make it implement | achieve an exchange determination function, an analysis function, etc. Furthermore, a plurality of components shown in FIG. 1, FIG. 5, or FIG. 9 may be integrated into one processor to realize a system control function, replacement determination function, erroneous replacement determination function, analysis function, and the like.

  Although several embodiments of the present invention have been described, these embodiments are presented by way of example and are not intended to limit the scope of the invention. These novel embodiments can be implemented in various other forms, and various omissions, replacements, and changes can be made without departing from the scope of the invention. These embodiments and modifications thereof are included in the scope and gist of the invention, and are included in the invention described in the claims and the equivalents thereof.

  DESCRIPTION OF SYMBOLS 1, 1A, 1B ... automatic analyzer, 2, 2A, 2B ... analysis mechanism, 3 ... drive part, 4 ... analysis part, 6 ... display part, 7 ... input part, 8 ... storage part 10, 10A, 10B ... System control unit, 11 ... reaction disk, 13 ... sample disk, 15 ... first reagent storage, 17 ... second reagent storage, 151, 171 ... reagent storage main body, 152, 172 ... reagent container rack, 19-1 ... sample Arm, 19-2 ... first reagent arm, 19-3 ... second reagent arm, 21-1 ... sample probe, 21-2 ... first reagent probe, 21-3 ... second reagent probe, 23 ... stirring arm, 25 ... Stirrer, 29 ... Cleaning mechanism, 31 ... Reaction tube, 33 ... Sample container, 35 ... First reagent container, 37 ... Second reagent container, 51 ... First notification section, 52-1, 52-2, 52a ... 2nd alerting | reporting part, 90-1, 90-1B, 9 -2,90-2B ... first detecting portion, 91-1,91-1B, 91-2,91-2B ... second detecting portion.

Claims (9)

A plurality of reagent containers, a reagent container capable of moving a reagent container to be replaced among the reagent containers to an exchange position; and
A drive unit for moving the reagent container;
A first detector that detects the presence or absence of the reagent container at the replacement position and determines whether or not the reagent container to be replaced at the replacement position has been replaced with a new reagent container based on the detection result ;
A control unit for controlling the movement of the reagent container to be exchanged ,
The first detection unit notifies the control unit that the exchange has been performed,
The control unit manages replacement list information related to a reagent container to be replaced specified in advance, receives the notification by the first detection unit, and among the reagent containers included in the replacement list information, An automatic analyzer that controls the drive unit to move a reagent container to be exchanged to the exchange position .   The automatic analyzer according to claim 1, further comprising a notification unit that notifies the outside of the replacement.   2. The automatic analysis according to claim 1, further comprising: a second detection unit that reads reagent information of the new reagent container and determines whether the new reagent container is correct based on the reagent information. apparatus. The automatic analyzer according to claim 3 , wherein the second detection unit is installed at the same location as the replacement position. 4. The automatic analyzer according to claim 3 , wherein the second detection unit is installed before reaching the reagent suction position where the reagent suction is performed downstream in the rotation direction as viewed from the replacement position. The automatic analyzer according to claim 3 , further comprising a notifying unit for notifying the outside of the result of the determination whether the replacement and the new reagent container are correct. The automatic analyzer according to claim 3 , wherein the second detection unit notifies the control unit of the determination result. When the control unit is notified of the determination result from the second detection unit and the content of the determination result indicates that the new reagent container is correct, the erroneously installed reagent container is in the replacement position. The automatic analyzer according to claim 7 , wherein the drive unit is controlled so as to move to a position. When the replacement of all the reagent containers included in the replacement list information is completed, the control unit moves the drive unit to move the replaced reagent container to a position where the second detection unit can detect the replacement. Controlling, reading the reagent information of the new reagent container, and controlling the second detection unit to determine whether or not the new reagent container is correct based on the reagent information. Item 9. The automatic analyzer according to Item 8 .