JP6585737B2 - セレブロン関連タンパク質の比を使用してがんの治療のための薬物の有効性を決定するための方法 - Google Patents

セレブロン関連タンパク質の比を使用してがんの治療のための薬物の有効性を決定するための方法 Download PDF

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JP6585737B2
JP6585737B2 JP2017563088A JP2017563088A JP6585737B2 JP 6585737 B2 JP6585737 B2 JP 6585737B2 JP 2017563088 A JP2017563088 A JP 2017563088A JP 2017563088 A JP2017563088 A JP 2017563088A JP 6585737 B2 JP6585737 B2 JP 6585737B2
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JP2018523105A5 (cg-RX-API-DMAC7.html
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英克 伊波
英克 伊波
詠美 池辺
詠美 池辺
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NATIONAL UNIVERSITY CORPORATION OITA UNIVERSITY
Celgene Corp
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JP2017563088A 2015-06-02 2016-06-01 セレブロン関連タンパク質の比を使用してがんの治療のための薬物の有効性を決定するための方法 Active JP6585737B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562170099P 2015-06-02 2015-06-02
US62/170,099 2015-06-02
US201562237905P 2015-10-06 2015-10-06
US62/237,905 2015-10-06
PCT/US2016/035198 WO2016196580A1 (en) 2015-06-02 2016-06-01 Methods for determining drug efficacy for treatment of cancer using ratios of cereblon associated proteins

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JP2018523105A JP2018523105A (ja) 2018-08-16
JP2018523105A5 JP2018523105A5 (cg-RX-API-DMAC7.html) 2019-05-16
JP6585737B2 true JP6585737B2 (ja) 2019-10-02

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US (1) US10338077B2 (cg-RX-API-DMAC7.html)
EP (1) EP3304076A4 (cg-RX-API-DMAC7.html)
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WO (1) WO2016196580A1 (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015085172A2 (en) 2013-12-06 2015-06-11 Celgene Corporation Methods for determining drug efficacy for the treatment of diffuse large b-cell lymphoma, multiple myeloma, and myeloid cancers
AU2016326499A1 (en) 2015-09-25 2018-04-12 Celgene Corporation Methods for treating diffuse large B-cell lymphoma and the use of biomarkers as a predictor of responsiveness to drugs
ES3042541T3 (en) 2016-01-08 2025-11-21 Celgene Corp Methods for treating cancer and the use of biomarkers as a predictor of clinical sensitivity to therapies
EP3422002B1 (de) 2017-06-26 2020-04-08 Bioscientia Institut für Medizinische Diagnostik GmbH Screeningverfahren zur diagnose einer hämatologischen neoplasie
TWI793151B (zh) 2017-08-23 2023-02-21 瑞士商諾華公司 3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途
AR116109A1 (es) 2018-07-10 2021-03-31 Novartis Ag Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
CR20210001A (es) 2018-07-10 2021-04-19 Novartis Ag Derivados de 3-(5-hidroxi-1-oxoisoindolin-2-il)piperidina-2,6-diona y su uso en el tratamiento de trastornos dependientes de la proteina con dedos de zinc 2 de la familia ikaros (1kzf2)
CA3114942A1 (en) * 2018-10-04 2020-04-09 Alfred Health Methods for monitoring response to treatment
CA3119526A1 (en) * 2018-12-03 2020-06-11 Dana-Farber Cancer Institute, Inc. Small molecule degraders of helios and methods of use
WO2020128972A1 (en) * 2018-12-20 2020-06-25 Novartis Ag Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
AU2021413227A1 (en) 2020-12-31 2023-07-13 Elephas Biosciences Corporation Ex vivo systems and methods for determining the effect of a drug or other agent on a tissue

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012125405A2 (en) * 2011-03-11 2012-09-20 Mayo Foundation For Medical Education And Research Methods and materials for assessing responsiveness to lenalidomide, thalidomide, and/or other thalidomide analogs
WO2012149299A2 (en) 2011-04-29 2012-11-01 Celgene Corporaiton Methods for the treatment of cancer and inflammatory diseases using cereblon as a predictor
EP3904875B1 (en) * 2012-06-29 2024-11-20 Celgene Corporation Methods for determining drug efficacy using ikzf3 (aiolos)
WO2014039960A1 (en) * 2012-09-10 2014-03-13 Celgene Corporation Methods for the treatment of locally advanced breast cancer
JP2016521280A (ja) * 2013-05-03 2016-07-21 セルジーン コーポレイション 併用療法を用いて癌を治療する方法
WO2015085172A2 (en) 2013-12-06 2015-06-11 Celgene Corporation Methods for determining drug efficacy for the treatment of diffuse large b-cell lymphoma, multiple myeloma, and myeloid cancers
KR20160090390A (ko) 2013-12-06 2016-07-29 셀진 코포레이션 혈액암의 치료방법 및 바이오마커를 사용한 레날리도마이드에 대한 임상적 민감도의 예측방법
JP2017533727A (ja) 2014-10-13 2017-11-16 セルジーン コーポレイション 固形腫瘍の治療方法及び免疫調節療法への臨床的感度の予測因子としてのバイオマーカーの使用
JP2018523823A (ja) 2015-08-04 2018-08-23 セルジーン コーポレイション 慢性リンパ球性白血病の治療方法及び免疫調節療法に対する臨床的感度の予測因子としてのバイオマーカーの利用
EP3334844A4 (en) 2015-08-12 2019-11-06 Celgene Corporation METHOD FOR THE TREATMENT OF SOLID TUMORS AND USE OF BIOMARKERS AS PREDICTORS OF CLINICAL SENSITIVITY TO IMMUNOMODULATORY THERAPIES
AU2016326499A1 (en) 2015-09-25 2018-04-12 Celgene Corporation Methods for treating diffuse large B-cell lymphoma and the use of biomarkers as a predictor of responsiveness to drugs
ES3042541T3 (en) 2016-01-08 2025-11-21 Celgene Corp Methods for treating cancer and the use of biomarkers as a predictor of clinical sensitivity to therapies

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WO2016196580A1 (en) 2016-12-08
US20160356778A1 (en) 2016-12-08
EP3304076A4 (en) 2018-12-19
US10338077B2 (en) 2019-07-02
EP3304076A1 (en) 2018-04-11
JP2018523105A (ja) 2018-08-16

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