JP6580883B2 - Pinch valve - Google Patents

Description

  The present invention relates to a pinch valve suitable for opening and closing a liquid flow path of a tube used in a liquid pharmaceutical or liquid drug substance production line.

In various production lines and various apparatuses, a flexible tube made of plastic, rubber, or the like is widely used for flowing liquid or gas.
Such a tube is often used in combination with a means for blocking a liquid or gas flow path as necessary.

Patent Document 1 discloses an apparatus for blocking the flow of liquid or gas flowing in a flexible tube.
In the apparatus of FIG. 1, the base 10 and the block 4 are fixed with four screws 4a. The block 4 has a lateral hole 5 through which a sleeve 7 made of porous rubber or porous plastic is passed. The sleeve 7 is fixed to the block 4 with two screws 7a. The tube 6 is passed through the sleeve 7.

At the time of operation, the plunger 8 is raised by the air pressure, and the tube 6 is crushed together with the sleeve 7 as shown in FIG. 1 so that the flow of liquid or gas passing through the tube 6 can be blocked.
It is described that the apparatus of FIG. 1 is used for dental treatment or the like in which an air flow containing abrasive particles is flowed (left column, lines 15 to 22 on page 1).

When attaching the tube 6 in the apparatus of FIG. 1, it is essential to pass it through the sleeve 7.
For this reason, it can be applied to a short tube such as a dental treatment application, but it is difficult to use a very long tube such as a tube used in a production line. When the shape is such that the tube is used or the tube is used via a plurality of devices, it cannot be applied.
Further, since the tube 6 is passed through the sleeve 7, it is difficult to precisely position the portion blocked by the plunger 8.

British Patent Application No. 2147394

  An object of the present invention is to provide a pinch valve capable of opening and closing a liquid flow at one place or a plurality of places regardless of the length or shape of a tube to be used.

The present invention is a pinch valve used for opening and closing a liquid flow path in a tube, having a tube cover, a tube holder and an actuator,
The tube cover has a first surface and a second surface on both sides in the thickness direction, and has a peripheral surface composed of two flat portions formed at positions facing each other in the radial direction and the remaining two curved portions. It has a substantially disc shape, and has, on the first surface side, a plate-like convex portion that passes through the center of the first surface and is formed between the two flat portions. Yes,
The tube holder has a first surface and a second surface on both sides in the thickness direction, and has a peripheral surface composed of two flat portions formed at positions opposed to each other in the radial direction and two remaining curved portions. It has a substantially disk shape,
The second surface includes a hole penetrating in the thickness direction including a central portion, and a first groove portion having a circular cross-sectional shape in the width direction formed between the two curved surface portions through the through hole. , Having a second groove formed in a direction passing through the through hole and orthogonal to the first groove,
The actuator includes a valve body moving space for moving a valve body penetrating in an axial direction from the first end surface to the second end surface, a valve body disposed in the valve body moving space, and the valve body by air pressure. Air supply means and air discharge means for moving in the axial direction,
The tube cover and the tube holder are detachably attached. When the tube cover is attached to the tube holder, the plate-like convex portion of the tube cover is fitted into the second groove portion of the tube holder. ,
The tube holder and the actuator are detachably attached,
The means for detachably attaching the tube cover and the tube holder is a combination of an elastic protrusion formed on the peripheral surface of the tube cover and a recess formed in the tube holder, and the elastic protrusion and the recess are fitted. By being combined, the tube cover and the tube holder are fixed, and a pinch valve is provided.

In the pinch valve of the present invention, a tube cover, a tube holder, and an actuator are detachably combined, and a desired position of the tube can be supported by the tube cover and the tube holder.
For this reason, regardless of the length or shape of the tube, the liquid flow path can be blocked or opened at a desired position of the tube.
Furthermore, in the pinch valve of the present invention, the tube cover and the tube holder are simply fixed by a combination of fixing means possessed by the tube cover and the tube holder, so that the tube is not displaced during fixation and use.

  The pinch valve of the present invention reliably opens and closes the liquid flow path at a desired location of the tube even when the tube is branched or when the tube is used in combination with a plurality of devices. Can do.

The perspective view of the state which attached the tube to the pinch valve of this invention. However, it is shown in a state where a part is cut out and the inner tube is visible. The exploded view of the pinch valve of the present invention. (A) is a front view of the tube cover used with the pinch valve of this invention, (b) is one side view, (c) is a top view. FIG. 3 is a longitudinal sectional view of a position including a center of a through hole when the tube holder and the actuator of FIG. 2 are combined. In FIG. 4, sectional drawing which removed the valve body and the piston. (A) is a front view of the valve body which can be used with the pinch valve of this invention, (b) is a front view of the valve body of different embodiment. 6A is a longitudinal sectional view of another embodiment of the valve body of FIG. 6A, and FIG. 6B is a longitudinal sectional view of another embodiment of the valve body of FIG. The perspective view of the valve body front-end | tip part used in FIG.7 (b). FIG. 6 is a longitudinal sectional view of a position including a center of a through hole when a tube is attached to the pinch valve of the present invention. (A) is explanatory drawing of the fixing method of the tube cover and tube holder in the pinch valve of this invention, (b) is a longitudinal cross-sectional view which shows the state after fixing. (A) is the elements on larger scale of the pinch valve shown in FIG. 9, (b) is a figure which shows the state after the action | operation of (a). (A) is the elements on larger scale when it sees from 90 degrees in FIG. 9, and (b) is a figure which shows the state after the action | operation of (a). (A) is a plan view of a tube holder used in a pinch valve of a different embodiment, (b) is a plan view of a tube cover combined with the tube holder of (a), and (c) is a tube holder of (b). The top view which shows the state which has arrange | positioned the tube to.

A pinch valve 1 shown in FIG. 1 has a tube cover 10, a tube holder 20, and an actuator 30, and shows a state in which a tube 70 is fixed.
In the pinch valve 1, the tube cover 10 and the tube holder 20 are detachably combined, and the tube holder 20 and the actuator 30 are detachably combined.

As shown in FIGS. 2 and 3A to 3C, the tube cover 10 has a substantially disc shape.
The tube cover 10 has a first surface 11a and a second surface 11b on both sides in the thickness direction.
The tube cover 10 has a circumferential surface composed of two flat surface portions 12a and 12b formed at positions facing each other in the radial direction and two curved surface portions 13a and 13b formed at positions facing the remaining radial direction. Have.
The tube cover 10 is preferably made of a synthetic resin, and is preferably transparent so that the open / closed state of the liquid flow path of the tube 70 can be confirmed with the naked eye.

The tube cover 10 has a plate-like convex portion 15 passing through the center (area center) of the first surface 11a in the first surface 11a.
The plate-like convex portion 15 extends from the flat surface 12a to the flat surface 12b side.
The plate-like convex portion 15 preferably has a cross-sectional shape in the width direction made of a square such as a square, a rectangle or a trapezoid.
The tube cover 10 has elastic protrusions 16a and 16b on two plane portions 12a and 12b, respectively. The elastic protrusions 16a and 16b are fixed from the inside by an elastic protrusion holder 17 (FIGS. 1 and 10B). The elastic protrusions 16a and 16 are for making the tube cover 10 and the tube holder 20 detachable.

As shown in FIG. 2, the tube holder 20 has a substantially disc shape and is made of metal or synthetic resin.
The tube holder 20 has a first surface 21a and a second surface 21b on both sides in the thickness direction.
The tube holder 20 has a peripheral surface composed of two plane portions 22a and 22b formed at positions facing each other in the radial direction and two curved surface portions 23a and 23b formed at positions facing the remaining radial direction. Have.

The tube holder 20 has a hole (through hole) 24 penetrating from the second surface 21b to the first surface 21a including the center (area center) of the second surface 21b in the second surface 21b.
The tube holder 20 has a first groove portion 25 that passes through the through-hole 24 and is formed between the two curved surface portions 23a and 23b and has a circular cross-sectional shape in the width direction. Since the first groove 25 is for fitting and holding the tube 70, the first groove 25 is adjusted to a size that allows the tube 70 to be used to be fitted.
The tube holder 20 has a second groove portion 26 that is formed in a direction that passes through the through hole 24 and is orthogonal to the length direction of the first groove portion 25. The second groove part 26 is divided into two at the first groove part 25.
The second groove portion 26 is to be fitted with the plate-like convex portion 15 of the tube cover 10.
As shown in FIGS. 4, 5, 9, and 12 (a) and 12 (b), the tube 70 is used at the portion where the first groove portion 25 and the second groove portion 26 intersect (the portion where the through hole 24 is present). In order to be expanded and crushed, an extended portion 25a in which the width of the first groove portion 25 is partially expanded is formed.
The expanded portion 25a is dimensioned in consideration of the width of the first groove portion 25 and the outer diameter of the tube 70, and the tube 70 is smaller than the width of the first groove portion 25. Thus, when a gap substantially corresponding to the extended portion 25a is formed from the difference in the outer diameters, the extended portion 25a may not be formed.

A first fixing plate 27 and a second fixing plate 28 are rotatably attached to the two flat portions 22a and 22b of the tube holder 20, respectively.
The first fixing plate 27 and the second fixing plate 28 have a recess 36 on each inner surface. The two recesses 36 have shapes and sizes that can be fitted into the two elastic protrusions 16 a and 16 b of the tube cover 10.
The tube cover 10 and the tube holder 20 can be attached or detached by a combination of the two elastic projections 16a and 16b and the two recesses 36.
The peripheral surface on the first surface 21 a side of the tube holder 20 has a threaded portion 29 for making the tube holder 20 and the actuator 30 detachable.

As shown in FIG. 2, the actuator 30 has a cylindrical shape and is made of synthetic resin or metal.
The actuator 30 includes a columnar first main body 31 and a columnar second main body 32.
The outer diameters of the first main body 31 and the second main body 32 are larger in the first main body 31, but the whole may have a uniform outer diameter or may have a different outer diameter. Good.
A screw portion 39 corresponding to the screw portion 29 of the tube holder 20 is formed on the first end face 30 a of the actuator 30.
In addition, since the 1st main-body part 31 and the 2nd main-body part 32 are fixed to a stand etc. at the time of use, you may have a hole for fixing with a volt | bolt etc., and also the flange part in which the said fixing hole was formed, etc. It may have.

As shown in FIGS. 4 and 5, the actuator 30 has a valve body moving space 40 for moving a valve body penetrating in the axial direction from the first end face 30 a to the second end face 30 b.
The valve body movement space 40 includes a first small-diameter space portion 41 on the first end surface 30a side, a second small-diameter space portion 43 on the second end surface 30b side, and between the first small-diameter space portion 41 and the second small-diameter space portion 43. The large-diameter space portion 42 is provided.
The first small-diameter space portion 41 on the first end face 30a side forms a space continuous with the through hole 24 of the tube holder 20 when assembled.
4 and 5, the inner diameters of the first small diameter space portion 41 and the second small diameter space portion 43 are the same, and the inner diameter of the large diameter space portion 42 is the inner diameter of the first small diameter space portion 41 and the second small diameter space portion 43. Is bigger than.
The inner diameter of the first small-diameter space portion 41 can be made larger than the inner diameter of the second small-diameter space portion 43 according to the shape of the distal end portion 51 of the valve body 50 to be used.

In the large-diameter space portion 42, a metal cylinder portion 45 is fixed to the inner peripheral surface 42a.
An annular piston portion 46 is disposed in the cylinder portion 45 so as to be in contact with the inner peripheral surface 45a and move in the cylinder portion 45 in the axial direction.
A cylindrical valve body 50 is fixed to the hole 46a of the annular piston 46 (FIG. 4), and the valve body 50 also moves in the axial direction when the annular piston 46 moves in the cylinder portion 45 in the axial direction. It is supposed to be.
The bottom surface (the bottom surface on the second end portion 30 b side) of the large-diameter space portion 42 and the annular piston 46 are not in contact with each other, and a first air introduction space 48 a is formed between the bottom surface and the annular piston 46. .
A first air introduction space 48 b is formed between the annular piston 46 in the large-diameter space portion 42 and the first surface 21 a of the tube holder 20.

The valve body 50 is disposed over a range from the first small diameter space 41 to the second small diameter space 43.
The valve body 50 is slidably brought into contact with the inner wall surface 41a of the first small diameter space portion 41 and the inner wall surface 43a of the second small diameter space portion 43, and the large diameter space 42, the first small diameter space 41, and Between the 2nd small diameter space 43, the entrance / exit of the air is substantially maintained in the blocked state.

The valve body 50 shown in FIG. 4 has a cylindrical shape as shown in FIG. 6A, and the tip 51 has a curved surface.
As shown in FIG. 7A, a valve body 50 having a tip 51 fixed to a main body 52 with a screw 53 can be used.
As the valve body 50 in FIG. 7A, a valve body 50 having an outer diameter larger than or smaller than the outer diameter of the main body 52 can be used depending on the outer diameter of the tube 70 to be used.
When the outer diameter of the tip 51 is made larger than the outer diameter of the main body 52, the inner diameter of the first small-diameter space 41 and the size of the through hole 24 of the tube holder 20 are adjusted.

As shown in FIG. 6B, the valve body 50 shown in FIG. 4 can use a valve body 55 having a tip 56 shaped as shown in FIG.
The tip 56 shown in FIG. 8 has a trapezoidal cross-sectional shape in the width direction, but may be square or rectangular.
The tip surface 56a of the tip portion 56 shown in FIG. 8 is a flat surface, but may be a curved surface.
The valve body 55 shown in FIG. 6B may be integrated as a whole, but as shown in FIG. 7B, the tip portion 56 may be fixed to the main body portion 57 with a screw 58. . The main body 57 and the main body 52 can be the same.
When the valve body 55 shown in FIG. 6B can be used, the inner diameter of the first small-diameter space 41 and the size of the through hole 24 of the tube holder 20 are adjusted.

The valve body 50 (valve body 55) is made of metal or synthetic resin. As shown in FIG. 7, when the main body 52 (main body 57) and the tip 51 (tip 56) are detachable, the main body 52 (main body 57) is made of metal so that the tube can be used during use. The tip 51 (tip 56) that contacts the 70 can be made of synthetic resin.
Use of the valve body 50 or 55 shown in FIG. 7 is preferable because only the tip 51 or 56 can be replaced according to the outer diameter of the tube.
In addition, when exchanging the front-end | tip part of the valve body 50 (valve body 55), the tube holder 20 can also be replaced as needed.

The actuator 30 has a first air supply port 60 for connection to the first external supply line 61 for air and a second connection for connection to the second external supply line 66 for air on the outer peripheral surface of the second main body portion 32. An air supply port 65 is provided.
The first air supply port 60 and the first air introduction space 48 a (inside the cylinder 45) are connected by a first internal supply line 62.
The second air supply port 65 and the second air introduction space 48 b are connected by a second internal supply line 67.

The tube cover 10 and the tube holder 20 are fixed to each other after the tube 70 is attached.
The two flat surfaces 12a and 12b opposed to the tube cover 10 in the radial direction have elastic protrusions 16a and 16b (FIG. 3) serving as fixing means for fixing to the tube holder 20.
As shown in FIG. 10, the first fixing plate 27 and the second fixing plate 28 are rotatable at the fulcrum 37 on one end side of the two planes 22 a and 22 b facing the radial direction of the tube holder 20. It is attached.
On the inner surfaces of the first fixing plate 27 and the second fixing plate 28, recesses 36 having a shape and a size that can be fitted to the elastic protrusions 16a and 16b are formed.
When the first fixing plate 27 and the second fixing plate 28 rotate at the fulcrum 37, the elastic protrusions 16a and 16b are fitted into the recesses 36, whereby the tube cover 10 and the tube holder 20 are tightened from both sides in the axial direction. Fixed.

Next, a method of using the pinch valve 1 of the present invention will be described with reference to FIGS. 2 and 9 to 11.
After the screw portion 29 of the tube holder 20 is screwed and attached to the screw portion 39 of the actuator 30 shown in FIG. 2, the tube 70 is disposed along the first groove portion 25.
The tube 70 is flexible and made of a synthetic resin (such as silicone) or rubber.
The inner diameter and the outer diameter of the tube 70 are different depending on the application of the pinch valve 1. For example, the inner diameter is 3.175 to 25.4 mm (1/8 to 1 inch), and the outer diameter is 6.35 to 38. It can be selected from the range of 1 mm (1/4 to 1.5 inches).
As an example, a tube made of silicone having an inner diameter of 12.7 mm, an outer diameter of 19.05 mm, and a thickness of 3.175 mm can be used as the tube 70.

When the tube 70 is disposed in the first groove portion 25, the position where the tube 70 is to be opened and closed coincides with the center of the through hole 24 (the center of the tip portion 51 of the valve body 50) and the extended portion 25a. Arrange so that.
In the pinch valve 1 of the present invention, the tube 70 can be fitted into the first groove portion 25 from above the tube holder 20 in a state where the tube cover 10 is not covered with the tube holder 20. Therefore, regardless of whether the tube 70 is branched or connected to other devices, the expanded portion 25a and the through hole 24 (the through hole 24 when there is no expanded portion 25a) of the first groove portion 25 and the tube 70. Therefore, the liquid flow path at the desired position can be fitted so that it can be opened and closed.

Next, the tube cover 10 is placed over the tube 70 disposed in the first groove portion 25 of the tube holder 20.
At this time, since the plate-like convex portion 15 of the tube cover 10 is fitted and covered in the second groove portion 26 of the tube holder 20, positioning is easy.

Next, as shown in FIG. 10, the first fixing plate 27 and the second fixing plate 28 that are rotatably attached to the two flat surfaces 22 a and 22 b of the tube holder 20 are rotated at the fulcrum, and the elastic protrusions 16 a and 16 b are rotated. Is fitted in the recess 36 to fix the tube cover 10 and the tube holder 20.
In FIGS. 10A and 10B, the first fixing plate 27 will be described. However, even when the second fixing plate 28 is used, it can be fixed in the same procedure.
In FIG. 10A, the first fixing plate 27 is indicated by a solid line, with the state before fixing being the first fixing plate 27a and the state after fixing being the first fixing plate 27b.

The first fixing plate 27 whose planar shape is substantially rectangular is in the position of the first fixing plate 27a before the tube cover 10 and the tube holder 20 are fixed (state of FIG. 4).
When the tube cover 10 and the tube holder 20 are fixed, the tube cover 10 and the tube holder 20 are rotated by 90 degrees at the fulcrum 37 and moved to the position of the second fixing plate 27b.
At this time, the tube cover 10 and the tube holder 20 are fixed to each other by fitting the recess 36 formed in the first fixing plate 27 into the elastic protrusion 16a formed on the flat surface 12a of the tube cover 10 ( The state of FIG.
Since the tube cover 10 and the tube holder 20 are not fixed at the time of fixing, the tube 70 is sandwiched and fixed by the tube cover 10 and the tube holder 20 from the upper and lower sides. There is nothing.

Next, an operation method of the pinch valve 1 will be described with reference to FIGS. 1, 9, 11, and 12.
The first air supply port 60 of the pinch valve 1 is connected to a compressed air source through a first external supply line 61 of air and a solenoid valve, and the second air supply port 65 is connected to a second external supply line 66 of air. And is opened through a solenoid valve.

When blocking the liquid flow path at a predetermined position of the tube 70 attached to the pinch valve 1, the electromagnetic valve of the first external supply line 61 for air is opened and the electromagnetic valve of the second external supply line 66 for air is closed. After that, high-pressure air is supplied from the compressed air source to the first air supply port 60 through the first external supply line 61 of air.
The high-pressure air supplied from the first air supply port 60 is introduced into the first air introduction space 48a from the first internal supply line 62 and pushes the annular piston 46 upward, so that the valve body 50 also moves upward. At this time, the annular piston 46 and the valve body 50 are raised until they collide with the first surface 21a of the tube holder 20, the first air introduction space 48a is enlarged by the same distance, and the second air introduction space 48b is the same distance. Can only be shrunk.
The plate shape of the tube cover 10 in the extended portion 25a of the first groove portion 25 by the movement of the valve body 50 as shown in FIGS. 11 (a) to 11 (b) and FIGS. 12 (a) to 12 (b). Since the tube 70 is crushed between the convex part 15 and the front-end | tip part 51 of the valve body 50, a liquid flow path is interrupted | blocked.

When opening the blocking portion of the tube 70 in the state shown in FIG. 11B and FIG. 12B, the electromagnetic valve of the second external supply line 66 of air is opened, and the first external supply line 61 of air is opened. After closing the solenoid valve, high pressure air is supplied from the compressed air source to the second air supply port 65 through the second external supply line 66 of air.
The high-pressure air supplied from the second air supply port 65 is introduced into the second air introduction space 48b from the second internal supply line 67 and pushes down the annular piston 46, so that the valve body 50 also moves downward. 11A and 12A, the liquid flow path of the tube 70 is opened.

In the pinch valve 1 of the present invention, a tube cover 10 and a tube holder 20, and a tube holder 20 and an actuator 30 are detachably combined.
Therefore, the tube cover 10 and the actuator 30 are left as they are, and only the tube holder 20 is replaced according to the outer diameter of the tube 70, or the actuator 30 is left as it is depending on the outer diameter of the tube 70. The tube cover 10 and the tube holder 20 can be exchanged.
The pinch valve 1 of the present invention can be configured so that the open / close state of the tube 70 can be confirmed by electrically connecting the actuator 30 and the sensor as necessary.
Further, when the pinch valve 1 of the present invention is used in a production line or the like, the pinch valve 1 can be used while being fixed to a stand or the like. For that purpose, a fixing bolt is inserted into the tube holder 20 and the actuator 30. A hole etc. can be formed suitably.

Next, an embodiment (three-way valve) that uses a plurality of pinch valves 1 of the present invention to open and close three liquid flow paths of a three-pronged tube will be described with reference to FIG.
In FIG. 13, an embodiment in which three actuators 130a, 130b, 130c share one tube cover 110 and one tube holder 120 is shown.
Each of the tube cover 110 and the tube holder 120 has three flat surfaces, and the same fixing means as shown in FIG. 10 is disposed on the three flat portions (not shown). It can be fixed with.

FIG. 13A is a plan view of the tube holder 120.
The tube holder 120 has a first a groove portion 125a, a first b groove portion 125b, and a first c groove portion 125c arranged in a trifurcated state.
The 1a groove part 125a has a 1a through hole 124a in the thickness direction, the 1b groove part 125b has a 1b through hole 124b in the thickness direction, and the 1c groove part 125c in the thickness direction. The first c through hole 124c is provided.
The tube holder 120 has a second a groove portion 126a, a second b groove portion 126b, and a second c groove portion 126c, which are formed in directions orthogonal to the length directions of the first a groove portion 125a, the first b groove portion 125b, and the first c groove portion 125c. is doing.
The tube holder 120 has the same actuators 130a and 130b as the actuator 30 shown in FIG. 2 so that the centers of the first a through hole 124a, the first b through hole 124b and the first c through hole 124c coincide with the center of the valve body 50. And 130c are connected.

FIG. 13B is a plan view of the tube cover 110.
The tube cover 110 has plate-like protrusions 115a, 115b, and 115c at three locations on the first surface 111a, respectively.

In the embodiment of FIG. 13, the assembly is performed as follows.
The three-pronged tube 170 (tubes 170a, 170b, 170c) is fitted along the 1a groove part 125a, the 1b groove part 125b, and the 1c groove part 125c of the tube holder 120 in FIG.

The plate-like protrusions 115a, 115b, 115c of the tube cover 110 shown in FIG. 13B are respectively provided to the 2a groove portion 126a, the 2b groove portion 126b, and the 2c groove portion 126c of the tube holder 120 of FIG. Fit.
Thereafter, the tube cover 110 and one tube holder 120 are fixed.

In the embodiment of FIG. 13, by opening and closing any one of the tubes 170a, 170b, and 170c, the liquid flow paths from the tubes 170a to 170b, the liquid flow paths from the tubes 170a to 170c, and the tubes 170b Any one of the liquid channels of the tube 170c can be maintained in an open / closed state.
In the embodiment of FIG. 13, the three actuators 120a, 120b, 120c share one tube cover 110 and one tube holder 120. As shown in FIG. 9, three pinch valves 1 are combined. Can also be used.

  The pinch valve of the present invention can be used to block or open a liquid passage in a plastic tube or rubber tube in a liquid pharmaceutical or liquid drug substance production line.

DESCRIPTION OF SYMBOLS 1 Pinch valve 10 Tube cover 15 Plate-shaped protrusion 20 Tube holder 24 Through-hole 25 1st groove part 25a Expansion part 26 2nd groove part 30 Actuator

Claims (5)

A pinch valve (1) having a tube cover (10), a tube holder (20), and an actuator (30) for use in opening and closing a liquid flow path in the tube,
The tube cover (10) has a first surface (11a) and a second surface (11b) on both sides in the thickness direction, and two flat portions (12a, 12b) formed at positions facing each other in the radial direction. ) And the remaining two curved surface portions (13a, 13b) having a substantially disk shape, the center of the first surface (11a) on the first surface (11a) side And having a plate-like convex part (15) formed between the two flat parts (12a, 12b),
The tube holder (20) has a first surface (21a) and a second surface (21b) on both sides in the thickness direction, and two plane portions (22a, 22b) formed at positions facing each other in the radial direction. ) And the remaining two curved surface portions (23a, 23b), and has a substantially disk shape.
The second surface (21b) is formed between the two curved surfaces (23a, 23b) passing through the through hole (24) and the hole (24) penetrating in the thickness direction including the center portion. In addition, the first groove portion (25) having a circular cross-sectional shape in the width direction and the second groove portion (26) formed in a direction perpendicular to the first groove portion (25) through the through hole (24) are provided. And
A valve body moving space (40) for moving the valve body (50) through which the actuator (30) passes in the axial direction from the first end face (30a) to the second end face (30b), and the valve body moving space (40) having a valve body (50) disposed in the interior, an air supply means and an air discharge means for moving the valve body (50) in the axial direction by air pressure,
The tube cover (10) and the tube holder (20) are detachably attached. When the tube cover (10) is attached to the tube holder (20), the plate-like protrusion of the tube cover (10) is provided. The portion (15) is fitted into the second groove (26) of the tube holder (20),
The tube holder (20) and the actuator (30) are detachably attached,
Removable attachment means for the tube cover (10) and the tube holder (20),
Elastic projections (16a, 16b) formed on the outer surface of the two flat portions of the tube cover (10), and a first rotatably attached to the two flat portions of the tube holder (20) A combination of a fixing plate (27) and a recess (36) formed on each inner surface of the second fixing plate (28) ;
A pinch valve in which the tube cover (10) and the tube holder (20) are fixed by fitting the elastic protrusions (16a, 16b) and the recess (36) .
The actuator has a valve body moving space for moving the valve body, which penetrates in an axial direction from the first end surface to the second end surface;
The valve body movement space (40) includes a first small-diameter space portion (41) on the first end portion (30a) side, a second small-diameter space portion (43) on the second end portion (30b) side, and the first Having a large diameter space portion (42) between one small diameter space portion (41) and the second small diameter space portion (43);
An inner diameter of the large diameter space portion (42) is larger than an inner diameter of the first small diameter space portion (41) and the second small diameter space portion (43);
The large-diameter space portion (42) is in contact with a cylinder portion (45) fixed to an inner wall surface (42a) and an inner wall surface (45a) of the cylinder portion (45), and the cylinder portion (45) An annular piston portion (46) arranged to be movable in the axial direction inside, and a valve fixed in the hole (46a) of the annular piston portion (46) and moved in the axial direction by the movement of the piston portion (46) Has a body (50),
In the range from the first small diameter space portion (41) to the second small diameter space portion (43), the valve body (50) and the inner wall surface (41a) of the first small diameter space portion (41) and the first 2 is slidably disposed on the inner wall surface (43a) of the small-diameter space portion (43),
The actuator (30) is connected to the first air supply port (60) for connecting to the first external supply line (61) for air and the second external supply line (66) for air on the peripheral wall surface. Second air supply port (65)
Further, a first air introduction space (48a) between the first air supply port (60), the annular piston (46) in the large diameter space portion (42) and the second small diameter space portion (43) is a first one. 1 connected by an internal supply line (62), between the second air supply port (65), the annular piston (46) in the large-diameter space portion (42), and the first small-diameter space portion (41). The pinch valve according to claim 1, wherein the second air introduction space (48b) is connected by a second internal supply line (67).   The pinch valve according to claim 1 or 2, wherein the valve body has a cylindrical shape or a prismatic shape, and includes a main body portion and a tip portion that is detachable from the main body portion. A detachable attachment means for attaching the tube cover and the tube holder,
Elastic protrusions on the outer surfaces of the two flat portions of the tube cover;
It consists of a combination of a first fixed plate and a second fixed plate, which are rotatably attached to two flat portions of the tube holder, each having a concave portion on its inner surface,
When the first fixing plate and the second fixing plate are rotated, the concave portions and the elastic protrusions of the tube cover are fitted to fix the tube cover and the tube holder. The pinch valve according to any one of claims 1 to 3, wherein   The pinch valve of any one of Claims 1-4 used for the tube of the manufacturing line of a liquid pharmaceutical or a liquid drug substance.

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