CN109414631B - Filter device - Google Patents
Filter device Download PDFInfo
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- CN109414631B CN109414631B CN201780041259.2A CN201780041259A CN109414631B CN 109414631 B CN109414631 B CN 109414631B CN 201780041259 A CN201780041259 A CN 201780041259A CN 109414631 B CN109414631 B CN 109414631B
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- Prior art keywords
- filter
- flow path
- screw portion
- forming member
- flow passage
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Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
- B01D29/01—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements
- B01D29/05—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements supported
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
- B01D46/0002—Casings; Housings; Frame constructions
- B01D46/0005—Mounting of filtering elements within casings, housings or frames
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
- B01D46/0002—Casings; Housings; Frame constructions
- B01D46/0012—In-line filters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
- B01D46/10—Particle separators, e.g. dust precipitators, using filter plates, sheets or pads having plane surfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/08—Flat membrane modules
- B01D63/087—Single membrane modules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2201/00—Details relating to filtering apparatus
- B01D2201/40—Special measures for connecting different parts of the filter
- B01D2201/4092—Threaded sections, e.g. screw
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2265/00—Casings, housings or mounting for filters specially adapted for separating dispersed particles from gases or vapours
- B01D2265/02—Non-permanent measures for connecting different parts of the filter
- B01D2265/028—Snap, latch or clip connecting means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2265/00—Casings, housings or mounting for filters specially adapted for separating dispersed particles from gases or vapours
- B01D2265/06—Details of supporting structures for filtering material, e.g. cores
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Filtration Of Liquid (AREA)
- Filtering Of Dispersed Particles In Gases (AREA)
Abstract
The invention provides a filter device capable of improving the sealing performance of a fluid flow path. The filter device according to the present invention includes: a first flow passage forming member in which a first flow passage through which a fluid flows is formed; a second flow passage forming member in which a second flow passage through which a fluid flows is formed; and a filter that is disposed so as to cross the first flow path or the second flow path and filters a filtering object included in the fluid, wherein the first flow path forming member is provided with a male screw portion, the second flow path forming member is provided with a female screw portion, and the first flow path forming member and the second flow path forming member are configured to have inclined surfaces inclined with respect to a screwing direction of the male screw portion and the female screw portion, respectively, on a side closer to the first flow path or the second flow path than the male screw portion and the female screw portion and to contact each other by the inclined surfaces in a state where the male screw portion and the female screw portion are screwed and the first flow path and the second flow path are communicated with each other.
Description
Technical Field
The present invention relates to a filter device for filtering a filtering object contained in a fluid.
Background
Conventionally, as such a filter facility, for example, a facility described in patent document 1 (for example, refer to japanese patent laid-open No. 2007-304016) is known.
The filter device of patent document 1 includes: a filter for filtering a filtering object included in a fluid; and a housing member having an internal space in which the filter is disposed and which serves as a fluid flow path. The housing member has: a disc-shaped base member; and a housing member having a recess on a lower surface thereof for forming an internal space, and a lower end portion fitted to an outer peripheral portion of the base member.
Prior art documents
Patent document
Patent document 1: japanese laid-open patent publication No. 2007-304016
Disclosure of Invention
Problems to be solved by the invention
However, in the conventional filter device as in patent document 1, it is difficult to process the fitting portion between the base member and the housing member with high accuracy. Therefore, there is a possibility that liquid leaks from the fluid flow path to the outside through the fitting portion, or that external air enters the fluid flow path from the outside through the fitting portion. Depending on the type of the outside air, there is a possibility that the object to be filtered is adversely affected.
To prevent the liquid leakage, it is conceivable to provide a rubber seal at the fitting portion to close the gap. However, in this case, the number of parts inevitably increases. Further, for example, in the case where the object to be filtered is a substance derived from a living organism, the rubber seal may adversely affect the substance derived from the living organism.
Therefore, in the conventional filter device, there is still room for improvement from the viewpoint of improving the sealing property of the flow path of the fluid.
An object of the present invention is to solve the above problems and to provide a filter device capable of improving the sealing property of a fluid flow path.
Means for solving the problems
In order to achieve the above object, a filter device according to an aspect of the present invention includes:
a first flow passage forming member in which a first flow passage through which a fluid flows is formed;
a second flow passage forming member in which a second flow passage through which a fluid flows is formed; and
a filter configured to filter an object to be filtered contained in the fluid by crossing the first flow path or the second flow path,
the first flow path forming member is provided with an externally threaded portion,
the second flow passage forming member is provided with an internal threaded portion,
in a state where the male thread portion and the female thread portion are screwed so that the first flow path and the second flow path communicate with each other, the first flow path forming member and the second flow path forming member are configured to have inclined surfaces inclined with respect to a screwing direction of the male thread portion and the female thread portion, respectively, on a side closer to the first flow path or the second flow path than the male thread portion and the female thread portion, and to contact each other by the inclined surfaces.
Effects of the invention
According to the filter device of the present invention, the sealing property of the fluid flow path can be improved.
Drawings
Fig. 1 is a perspective view showing a schematic configuration of a filter device according to embodiment 1 of the present invention.
Fig. 2 is an exploded perspective view of the filter apparatus of fig. 1.
Fig. 3 is an exploded perspective view showing a portion of the filter apparatus of fig. 1 in partial section.
Fig. 4 is an assembled cross-sectional view of the filter apparatus of fig. 1.
Fig. 5 is a partially enlarged sectional view of fig. 4.
Fig. 6 is a partially enlarged perspective view showing a schematic structure of the filter.
Fig. 7 is a side view schematically showing how the filter is held by the holding member on the fluid supply side and the filter filters a filtering object included in the fluid.
Fig. 8 is a side view schematically showing a state in which the filter object filtered by the filter shown in fig. 7 is subjected to back-flow washing by passing a liquid in a reverse direction.
Fig. 9 is a side view schematically showing how the filter is held by the holding member on the fluid discharge side and the filter filters a filtering object included in the fluid.
Fig. 10 is a side view schematically showing a state in which liquid is put in the space surrounded by the filter and the holding member shown in fig. 9 and the object to be filtered is floated in the liquid.
Fig. 11 is a plan view schematically showing a modification of the filter.
Fig. 12 is a perspective view showing a schematic configuration of a filter device according to embodiment 2 of the present invention.
Fig. 13 is an exploded perspective view of the filter apparatus of fig. 12.
Fig. 14 is a perspective view showing a schematic configuration of a filter device according to embodiment 3 of the present invention.
Fig. 15 is a partially exploded perspective view of the filter apparatus of fig. 14.
Fig. 16 is a cross-sectional view of the filter apparatus of fig. 14.
Detailed Description
A filter device according to an aspect of the present invention includes:
a first flow passage forming member in which a first flow passage through which a fluid flows is formed;
a second flow passage forming member in which a second flow passage through which a fluid flows is formed; and
a filter configured to filter an object to be filtered contained in the fluid by crossing the first flow path or the second flow path,
the first flow path forming member is provided with an externally threaded portion,
the second flow passage forming member is provided with an internal threaded portion,
in a state where the male thread portion and the female thread portion are screwed so that the first flow path and the second flow path communicate with each other, the first flow path forming member and the second flow path forming member are configured to have inclined surfaces inclined with respect to a screwing direction of the male thread portion and the female thread portion, respectively, on a side closer to the first flow path or the second flow path than the male thread portion and the female thread portion, and to contact each other by the inclined surfaces.
According to this configuration, the first flow passage forming member and the second flow passage forming member can be attached and detached freely and more reliably by screwing the external thread portion and the internal thread portion. Further, since the first flow passage forming member and the second flow passage forming member are made to contact each other by the inclined surface, the contact area can be increased as compared with the case where the contact is made by a surface orthogonal to the screwing direction. According to this configuration, even if the machining accuracy is about the same as that of the configuration in which the contact is made by the orthogonal surfaces, the number of portions where the first channel-forming member and the second channel-forming member are in close contact with each other can be substantially increased, and the sealing property of the channel of the fluid can be further improved.
Further, it is preferable that a gap is provided between the male screw portion and the second flow passage forming member in the screwing direction in a state where the male screw portion and the female screw portion are screwed. According to this configuration, since the clearance is provided, the amount of screwing of the male screw portion and the female screw portion can be further increased in a state where the inclined surfaces are in contact with each other. As a result, the contact pressure between the inclined surfaces can be increased, the portion where the first channel-forming member and the second channel-forming member are in close contact can be further increased, and the fluid channel can be further sealed.
Further, it is preferable that a gap is provided between the internal thread portion and the first flow passage forming member in the screwing direction in a state where the external thread portion and the internal thread portion are screwed. According to this configuration, the gap prevents the female screw portion from coming into contact with the first flow passage forming member and the amount of screwing between the female screw portion and the male screw portion from increasing. Further, by checking the size of the gap, it is possible to estimate whether or not the inclined surfaces are firmly in close contact with each other, whether or not foreign matter or the like exists between the male screw portion and the second flow passage forming member.
Further, according to the above configuration, since the sealing property of the flow path of the fluid can be further improved, the filter may include a metal porous membrane capable of filtering the substance derived from the living organism as the object to be filtered.
Further, at least one of the first flow passage forming member and the second flow passage forming member may be a holding member that holds an outer peripheral portion of the filter.
Hereinafter, embodiments of the present invention will be described with reference to the drawings.
(embodiment mode 1)
Fig. 1 is a perspective view showing a schematic configuration of a filter device according to embodiment 1 of the present invention. Fig. 2 is an exploded perspective view of the filter apparatus of fig. 1. Fig. 3 is an exploded perspective view showing a portion of the filter apparatus of fig. 1 in partial section. Fig. 4 is an assembled cross-sectional view of the filter apparatus of fig. 1. Fig. 5 is a partially enlarged sectional view of fig. 4.
As shown in fig. 1 and 2, a filter device according to embodiment 1 of the present invention includes a holding member 1, a cylindrical member 2 detachably attached to one main surface 1a side of the holding member 1, and a cylindrical member 3 detachably attached to the other main surface 1b side of the holding member 1.
As shown in fig. 3 and 4, the holding member 1 is configured to hold the outer peripheral portion 4A of the filter 4, and the filter 4 filters a filtering object included in the fluid. In embodiment 1, the holding member 1 includes a first frame member 11 and a second frame member 12. The first frame member 11 and the second frame member 12 are configured to be able to sandwich the outer peripheral portion 4A of the filter 4 therebetween.
More specifically, the first frame member 11 includes an annular flat plate portion 11a and an annular convex portion 11c in which a portion around the central through hole 11b protrudes toward the cylindrical member 2 in the thickness direction of the holding member 1. The diameter of the flat plate portion 11a is, for example, 18 mm. The thickness of the flat plate portion 11a is, for example, 0.9 mm. The diameter of the through hole 11b is, for example, 8 mm. The height of the projection 11c is, for example, 4.1 mm. As will be described later in detail, the inclined surface 11i is formed on the projection 11 c.
An annular flange 11d protruding toward the center of the through hole 11b is formed on the inner surface of the annular convex portion 11 c. The flange portion 11d is provided at a position spaced apart from the top of the convex portion 11c toward the flat plate portion 11a by 0.2mm in the thickness direction of the holding member 1, for example. The central front end 11f of the through hole 11b of the flange 11d is formed to be thin so that an inclined surface 11e is formed on the cylindrical member 3 side. The flange 11d has a thickness of 0.5mm on the side of the convex portion 11c, for example. The thickness of the tip portion 11f of the flange portion 11d is, for example, 0.2 mm. The inclination angle of the inclined surface 11e is, for example, 60 degrees.
The second frame member 12 includes: an annular flat plate portion 12 a; an annular convex portion 12c protruding toward the cylindrical member 2 in the thickness direction of the holding member 1 at a portion around the central through hole 12 b; and a recess 12d in which a portion around the central through hole 12b is recessed toward the cylindrical member 2 in the thickness direction of the holding member 1. The diameter of the flat plate portion 12a is 18mm, for example. The thickness of the flat plate portion 12a is, for example, 4.9 mm. The diameter of the through hole 12b is, for example, 6 mm. The height of the projection 12c is, for example, 4.65 mm.
The convex portion 12c has an outer diameter slightly smaller than the diameter of the through hole 11b of the first frame member 11 so as to be insertable into the through hole 11 b. The tip end 12f of the convex portion 12c is formed to correspond to the shape of the flange portion 11d on the cylindrical member 3 side. That is, the inclined surface 12e corresponding to the inclined surface 11e is formed at the tip end portion 12 f.
As shown in fig. 5, the filter 4 is held in a state of having tension in the plane direction by sandwiching the outer peripheral portion 4A between the flange portion 11d of the first frame member 11 and the tip end portion 12f of the projection portion 12c of the second frame member 12 so as to follow the inclined surface 11e and the inclined surface 12 e. Further, the filter 4 is held between the outer peripheral portion 4A and the holding member 1 at a position offset in the thickness direction from the center plane S1 in the thickness direction. In embodiment 1, the filter 4 is disposed inside the annular projection 11 c. The filter 4 is disposed substantially flush with an opening surface S2 defined by the distal end of the annular projection 11 c.
As shown in fig. 3 and 4, the flat plate portion 11a of the first frame member 11 is provided with a plurality of through holes 11g penetrating in the thickness direction. The plurality of through holes 11g are provided at regular intervals in the circumferential direction of the flat plate portion 11 a. Similarly, a plurality of pins 12g protruding in the thickness direction are provided on the flat plate portion 12a of the second frame member 12. The plurality of pins 12g are provided at regular intervals in the circumferential direction of the flat plate portion 12a so as to correspond to the plurality of through holes 11 g. The first frame member 11 and the second frame member 12 are fixed to each other by inserting the convex portion 12c of the second frame member 12 into the through hole 11b of the first frame member 11 and inserting the pin 12g into each through hole 11 g.
The cylindrical member 2 includes a concave portion 2a detachably attached to the convex portion 11c of the first frame member 11. The concave portion 2a has an inner diameter larger than that of the convex portion 11 c. The cylindrical member 2 is formed with a hollow portion 2b serving as a flow path of the fluid. The cylindrical member 2 is attached to the first frame member 11 such that the hollow portion 2b faces at least a part of the main surface of the filter 4. This enables the fluid to be supplied to the filter 4 using the hollow portion 2b as a fluid supply passage. Alternatively, the hollow portion 2b may be used as a fluid discharge passage to discharge the fluid that has passed through the filter 4.
As shown in fig. 5, a female screw portion 2d is formed on the inner peripheral surface of the recess 2a of the tubular member 2. The recess 2a of the tubular member 2 has an inclined surface (hereinafter, referred to as an inclined inner peripheral surface) 2e on the side closer to the flow path (hollow portion 2b) than the female screw portion 2 d. An external thread portion 11h corresponding to the internal thread portion 2d is provided on the outer peripheral surface of the convex portion 11c of the first frame member 11. The convex portion 11c of the first frame member 11 has an inclined surface (hereinafter, an inclined outer peripheral surface) 11i on the side closer to the flow path (through hole 12b) than the male screw portion 11 h. The inclined inner circumferential surface 2e and the inclined outer circumferential surface 11i are formed to be inclined with respect to the screwing direction (axial direction) of the male screw portion 11h and the female screw portion 2 d.
The inclined inner circumferential surface 2e and the inclined outer circumferential surface 11i are formed in a tapered shape. The inclined inner circumferential surface 2e has an outer diameter smaller than the female screw portion 2d as viewed in the axial direction so as to be included in the female screw portion 2 d. The inclined outer peripheral surface 11i has a smaller outer diameter than the male threaded portion 11h as viewed in the axial direction so as to be included in the male threaded portion 11 h. As shown in fig. 5, in a state where the female screw portion 2d and the male screw portion 11h are screwed, the convex portion 11c of the first frame member 11 and the concave portion 2a of the tubular member 2 are configured to contact each other via the inclined inner peripheral surface 2e and the inclined outer peripheral surface 11 i. The inclination angles of the inclined inner circumferential surface 2e and the inclined outer circumferential surface 11i are, for example, 60 degrees.
Further, in a state where the female screw portion 2d and the male screw portion 11h are screwed, gaps C1, C2 are formed between the female screw portion 2d and the cylindrical member 2 in the screwing direction (the up-down direction in fig. 5) and between the male screw portion 11h and the first frame member 11 in the screwing direction.
The cylindrical member 2 is provided with a Luer lock connector (Luer lock connector)2 c. The luer lock type connector 2c has a form conforming to the standard of ISO594-2 or the like, for example. In embodiment 1, the connector 2c is formed of an annular projection provided to project outward from the distal end of the tubular member 2. The cylindrical member 2 is fitted to a Luer lock type syringe (Luer lock syringe) by screwing a connector 2c along a spiral groove (not shown) formed on the inner peripheral surface of the hollow distal end of the syringe.
The cylindrical member 3 includes a convex portion 3a detachably attached to a concave portion 12d of the second frame member 12. The concave portion 12d has an inner diameter larger than that of the convex portion 3 a. The cylindrical member 3 is formed with a hollow portion 3b serving as a flow path for the fluid. The cylindrical member 3 is fitted to the second frame member 12 such that the hollow portion 3b faces at least a part of the main surface of the filter 4. This enables the fluid to be supplied to the filter 4 using the hollow portion 3b as a fluid supply passage. Alternatively, the hollow portion 3b may be used as a fluid discharge passage to discharge the fluid that has passed through the filter 4.
Further, the cylindrical member 3 is provided with a luer lock type connector 3 c. The luer lock type connector 3c has a form conforming to the standard of ISO594-2 or the like, for example. In embodiment 1, the connector 3c is formed of an annular projection provided to project outward from the distal end of the tubular member 3. The cylindrical member 3 is fitted to a luer lock type syringe by screwing a connector 3c along a spiral groove (not shown) formed on the inner peripheral surface of the hollow distal end portion of the syringe.
Examples of the material of the first frame member 11, the second frame member 12, and the tubular members 2 and 3 include metals such as duralumin and aluminum, and resins such as polyethylene, polystyrene, polypropylene, polycarbonate, polyacetal, and polyetherimide.
In embodiment 1, the object to be filtered is a substance derived from a living organism contained in a liquid. In the present specification, the term "biologically derived substance" refers to a substance derived from a living organism, such as a cell (eukaryote), a bacterium (eubacterium), or a virus. Examples of the cells (eukaryotes) include eggs, sperm, artificial pluripotent stem cells (iPS cells), ES cells, stem cells, mesenchymal stem cells, monocyte cells, unicellular cells, cell masses, planktonic cells, adhesive cells, nerve cells, leukocytes, lymphocytes, regenerative medicine cells, autologous cells, cancer cells, circulating blood cancer cells (CTCs), HL-60, HELA, and fungi. Examples of the bacteria (eubacteria) include Escherichia coli and tubercle bacillus.
Fig. 6 is a partially enlarged perspective view showing a schematic configuration of the filter 4. As shown in fig. 6, the filter 4 includes a metal porous membrane 41 for filtering a filtering object included in the fluid.
As shown in fig. 6, the metal porous film 41 has a pair of main surfaces 41a and 41b facing each other. The metal porous membrane 41 is provided with a plurality of through holes 41c penetrating through both the main surfaces 41a and 41 b. The through-hole 41c is a through-hole for separating a substance derived from a living organism from a liquid. The shape and size of the through-hole 41c are appropriately set according to the shape and size of the substance derived from a living organism. The through holes 41c are arranged at equal intervals or periodically, for example. The shape of the through-hole 41c is, for example, any one of a square, a regular hexagon, a circle, and an ellipse when viewed from the main surface 41a side of the metal porous membrane 41. In embodiment 1, the through holes 41c are arranged in a square lattice shape. The size of the through-hole 41c is, for example, 0.1 μm to 500 μm in the vertical direction and 0.1 μm to 500 μm in the horizontal direction when the through-hole 41c is square. The interval between the through holes 41c is, for example, one time to ten times or less, and more preferably three times or less, larger than the opening diameter of the through holes 41 c. The aperture ratio of the through-holes 41c in the metal porous film 41 is, for example, 10% or more.
Examples of the material of the metal porous film 41 include gold, silver, copper, platinum, nickel, stainless steel, palladium, titanium, cobalt, alloys thereof, and oxides thereof. The size of the metal porous film 41 is, for example, 6mm in diameter. The thickness of the metal porous film 41 is, for example, 0.1 μm or more and 100 μm or less, and preferably 0.1 μm or more and 50 μm or less. The outer shape of the metal porous membrane 41 is, for example, any one of a circular shape, an oval shape, and a polygonal shape. In embodiment 1, the outer shape of the metal porous membrane 41 is circular. The through-hole 41c may be provided or not provided in the outer peripheral portion of the metal porous membrane 41.
According to embodiment 1, as shown in fig. 5, the male screw portion 11h is provided on the outer peripheral surface of the convex portion 11c of the holding member 1, and the female screw portion 2d is provided on the inner peripheral surface of the concave portion 2a of the cylindrical member 2. In a state where the male screw portion 11h and the female screw portion 2d are screwed, the convex portion 11c of the holding member 1 and the concave portion 2a of the cylindrical member 2 are configured to contact each other via the inclined outer circumferential surface 11i and the inclined inner circumferential surface 2 e. According to this configuration, the holding member 1 and the tubular member 2 can be attached and detached freely and more reliably by screwing the male screw portion 11h and the female screw portion 2 d. Further, since the convex portion 11c of the holding member 1 and the concave portion 2a of the cylindrical member 2 are brought into contact with each other through the inclined outer peripheral surface 11i and the inclined inner peripheral surface 2e, the contact area can be increased as compared with the case where the contact is made through a surface orthogonal to the screwing direction. According to this configuration, even if the processing accuracy is about the same as that of the configuration in which the contact is made by the orthogonal surfaces, the portion where the convex portion 11c of the holding member 1 and the concave portion 2a of the cylindrical member 2 are in close contact can be substantially increased, and the sealing property of the flow path of the fluid can be further improved. In this configuration, the holding member 1 corresponds to the first channel forming member, and the through hole 12b of the holding member 1 corresponds to the first channel. The filter 4 is arranged to cross the first flow path. Further, the cylindrical member 2 corresponds to a second flow passage forming member, and the hollow portion 2b of the cylindrical member 2 corresponds to a second flow passage.
Further, according to embodiment 1, in a state where the female screw portion 2d and the male screw portion 11h are screwed, a gap C1 is formed between the male screw portion 11h and the cylindrical member 2 in the screwing direction. The clearance C1 allows the female screw portion 2d and the male screw portion 11h to be screwed in a further increased amount while the inclined outer circumferential surface 11i is in contact with the inclined inner circumferential surface 2 e. As a result, the contact pressure between the inclined outer circumferential surface 11i and the inclined inner circumferential surface 2e can be increased, the portion where the cylindrical member 2 and the holding member 1 are in close contact can be further increased, and the sealing property of the fluid flow path can be further improved.
Further, as shown in fig. 5, gaps C2, C3 are preferably formed between the female screw portion 2d and the holding member 1 in the screwing direction. The clearances C2 and C3 prevent the amount of screwing of the female screw portion 2d into the male screw portion 11h from increasing due to contact between the female screw portion 2d and the holding member 1 or contact between the flange portion 11d and the cylindrical member 2. When the female screw portion 2d and the male screw portion 11h are screwed together, it is confirmed that the amount of screwing cannot be increased in a state where the clearance C2 is present, and it can be estimated that the inclined inner circumferential surface 2e and the inclined outer circumferential surface 11i are firmly in close contact with each other. In addition, when the gap C2 or the gap C3 is larger than the predetermined gap in the state where the amount of screwing cannot be increased, it is possible to estimate that foreign matter is present in the gap C1 or that the multi-piece filter 4 is sandwiched between the first frame member 11 and the second frame member 12. In contrast, when the gap C2 or the gap C3 is not provided in a state where the screwing amount cannot be increased, it is possible to estimate that there is a space between the inclined inner peripheral surface 2e and the inclined outer peripheral surface 11i, or the filter 4 or the like is not sandwiched between the first frame member 11 and the second frame member 12. Further, by providing the step 11da in the flange portion 11d, the contact area between the inclined outer circumferential surface 11i and the inclined inner circumferential surface 2e can be increased, the sealing performance can be improved, and the gap C3 can be formed.
Further, as described with reference to fig. 5, a female screw portion may be provided on the inner peripheral surface of the concave portion 12d of the holding member 1, and a male screw portion may be provided on the outer peripheral surface of the convex portion 3a of the cylindrical member 3. The concave portion 12d of the holding member 1 and the convex portion 3a of the cylindrical member 3 may be configured to have an inclined surface inclined with respect to the screwing direction of the female screw portion and the male screw portion on the side closer to the flow path than the female screw portion and the male screw portion, and to be in contact with each other by the inclined surface. According to this configuration, the holding member 1 and the cylindrical member 3 can be attached to and detached from each other more reliably by screwing the internal thread portion and the external thread portion. Further, since the concave portion 12d of the holding member 1 and the convex portion 3a of the cylindrical member 3 are brought into contact with each other by the inclined surfaces, the contact area can be increased as compared with the case where the contact is made by the surfaces orthogonal to the screwing direction. According to this configuration, even if the machining accuracy is about the same as that of the configuration in which the contact is made by the orthogonal surfaces, the portion where the concave portion 12d of the holding member 1 and the convex portion 3a of the cylindrical member 3 are in close contact with each other can be substantially increased, and the sealing property of the flow path of the fluid can be further improved. In this configuration, the holding member 1 corresponds to the second channel forming member, and the through hole 12b of the holding member 1 corresponds to the second channel. The filter 4 is arranged to cross the second flow path. Further, the cylindrical member 3 corresponds to a first flow path forming member, and the hollow portion 3b of the cylindrical member 3 corresponds to a first flow path.
Further, as described with reference to fig. 5, in a state where the male screw portion and the female screw portion are screwed, a gap may be formed between the male screw portion and the holding member 1 in the screwing direction. With these clearances, the amount of screwing of the female screw portion and the male screw portion can be increased in a state where the inclined surfaces are in contact with each other. As a result, the contact pressure between the inclined surfaces can be increased, the portion where the cylindrical member 3 and the holding member 1 are in close contact can be further increased, and the fluid passage can be further sealed. Further, a gap may be formed between the female screw portion and the cylindrical member 3 in the screwing direction. This gap can avoid the situation in which the female screw portion comes into contact with the cylindrical member 3 and the screwing amount cannot be increased. By checking the size of the gap, it is possible to estimate whether or not the inclined surfaces are firmly in close contact with each other, whether or not foreign matter is present between the external thread portion and the holding member 1, and the like.
Further, according to embodiment 1, the sealing property of the flow path of the fluid can be further improved, and therefore the filter 4 can be provided with the metal porous membrane 41 that can filter the substance derived from the living organism as the object to be filtered. By providing the metal porous membrane 41, it is possible to suppress or eliminate the occurrence of irregularities on both main surfaces, and it becomes easier to focus when the object to be filtered remaining on the filter 4 is observed with an electron microscope or the like.
Further, according to embodiment 1, as shown in fig. 4, since the filter 4 is disposed inside the convex portions 11c and 12c of the holding member 1, the filter 4 is disposed on the fluid supply side or the fluid discharge side with being offset in the thickness direction of the holding member 1 with respect to the center plane S1. That is, when the fluid passage formed by the convex portions 11c and 12c of the holding member 1 is used as the fluid supply passage, the filter 4 is disposed on the fluid supply side. With this configuration, as shown in fig. 7, focusing is facilitated when the object x to be filtered remaining on the filter 4 is observed with an electron microscope or the like. As shown in fig. 8, it is advantageous to perform so-called back flushing in which the filter object x remaining on the filter 4 is separated from the filter 4 by passing the fluid in the reverse direction. On the other hand, when the fluid passage formed by the convex portions 11c and 12c of the holding member 1 is used as the fluid discharge passage, the filter 4 is disposed on the fluid discharge side. Further, as shown in fig. 9, the space surrounded by the holding member 1 and the filter 4 can be enlarged. With this configuration, as shown in fig. 10, the volume of the liquid L can be increased, and the object x to be filtered can be observed in a state of being immersed in the liquid more reliably. Therefore, the filtering object x remaining on the filter 4 can be observed more favorably by preventing drying, activating, or the like. Further, when the cylindrical member 2 is removed, the fluid can be prevented from overflowing from the space and leaking, and the filter 4 can be more reliably caused to filter the object to be filtered.
Further, according to embodiment 1, the filter 4 is disposed substantially flush with the opening surface S2 defined by the distal end portion of the annular convex portion 11 c. With this configuration, focusing becomes easier when the object to be filtered remaining on the filter 4 is observed with an electron microscope or the like. Further, the volume of the space surrounded by the holding member 1 and the filter 4 can be further increased, and the filter 4 can be more reliably caused to filter the object to be filtered. In addition, the filter 4 may be configured to be flush with respect to the opening face S2. In this case, the same effect can be obtained.
Further, according to embodiment 1, the holding member 1 includes the first frame member 11 and the second frame member 12, and the outer peripheral portion 4A of the filter 4 can be sandwiched therebetween. According to this configuration, the filter 4 can be easily replaced by releasing the clamping between the first frame member 11 and the second frame member 12.
Further, according to embodiment 1, it is preferable that the thickness of the flat plate portion 11a that becomes the outer peripheral portion of the first frame member 11 is different from the thickness of the flat plate portion 12a that becomes the outer peripheral portion of the second frame member 12. Thus, even when the holding member 1 is mounted on the tubular members 2 and 3 and the convex portions 11c and 12c and the concave portion 12d cannot be visually recognized in appearance, the positions of the convex portions 11c and 12c and the concave portion 12d can be confirmed based on the difference in thickness of the flat plate portions 11a and 12 a.
Further, according to embodiment 1, the cylindrical members 2, 3 are provided with luer lock type connectors 2c, 3 c. With this configuration, for example, the syringe can be directly attached to a luer lock type syringe, and usability can be improved.
In embodiment 1, as shown in fig. 5, the outer peripheral portion 4A of the filter 4 is sandwiched between the inclined surface 11e of the first frame member 11 and the inclined surface 12e of the second frame member 12, so that the outer peripheral portion 4A of the filter 4 has the first bent portion 4A and the second bent portion 4 b. At this time, as shown in fig. 11, the outer peripheral portion 4A of the filter 4 is preferably sandwiched between the first bent portion 4A and the second bent portion 4b so as to have a rib-like convex portion 4 c. According to this configuration, the rib-like protrusions 4c can increase the frictional force between the first frame member 11 and the second frame member 12 and the outer peripheral portion 4A of the filter 4. This can improve the holding force of the first frame member 11 and the second frame member 12 with respect to the filter 4 without increasing the number of components. The rib-like projection 4c is a portion where one main surface of the filter 4 projects at a height of about 0.1 to twice as large as the thickness of the filter 4.
As shown in fig. 11, a plurality of rib-shaped protrusions 4c are preferably provided between the first bent portion 4a and the second bent portion 4b, and the plurality of rib-shaped protrusions 4c are preferably arranged in an irregular orientation. According to this configuration, the frictional force between the first frame member 11 and the second frame member 12 and the outer peripheral portion 4A of the filter 4 can be increased, and the holding force of the first frame member 11 and the second frame member 12 on the filter 4 can be further improved.
The rib-like protrusions 4c may be formed by the folds of the metal porous membrane 41. Here, the term "wrinkle" refers to a fine texture formed by loosening or shrinking the metal porous film 41. In this case, the rib-like convex portions 4c can be formed by the metal porous film 41 itself, and the need to provide a separate member as the rib-like convex portions 4c can be eliminated.
The present invention is not limited to the above embodiments, and can be implemented in various other embodiments. For example, although the filtering object is made of a biologically-derived material contained in a liquid in the foregoing description, the present invention is not limited to this. The object to be filtered may be a substance contained in a gas. That is, the object to be filtered may be any object contained in the fluid, and may be, for example, PM2.5 contained in the air.
In the foregoing, the filter 4 is used to filter a substance derived from a living organism from a liquid, but the present invention is not limited thereto. For example, the filter 4 may also be used for concentrating liquids.
In the above description, the cylindrical member 2 is detachably attached to the one main surface 1a side of the holding member 1, but the present invention is not limited to this. For example, the cylindrical member 2 may be detachably attached to the side surface of the holding member 1.
(embodiment mode 2)
Fig. 12 is a perspective view showing a schematic configuration of a filter device according to embodiment 2 of the present invention. Fig. 13 is an exploded perspective view of the filter apparatus of fig. 12.
The filter device according to embodiment 2 is different from the filter device according to embodiment 1 in that it is configured to include two holding members 1 and 1. Note that the same or similar members as those described in embodiment 1 are denoted by the same reference numerals, and redundant description thereof is omitted.
The two holding members 1, 1 are detachably assembled to each other. In embodiment 2, the convex portion 11c of the first frame member 11 has a shape that can be fitted into the concave portion 12d (see fig. 3 and 4) of the second frame member 12. That is, the convex portion 11c of the first frame member 11 has the same shape as the convex portion 3a of the cylindrical member 3. The recess 12d of the second frame member 12 has the same shape as the recess 2a (see fig. 3 and 4) of the cylindrical member 2.
According to embodiment 2, since the two holding members 1 and 1 are detachably provided, the two filters 4 can be easily attached to and detached from one filter device, and usability can be improved. For example, since the filtering object can be filtered by the two filters 4, it is possible to reduce variation in the size of the filtering object filtered by the filter located on the downstream side in the flow direction of the fluid among the two filters 4. Further, by making the pore diameters of the filters 4 held by the holding members 1 different, it is possible to classify the filtering objects having different sizes.
In embodiment 2, the convex portion 11c of the first frame member 11 has a shape that can be fitted into the concave portion 12d of the second frame member 12, and therefore, for example, three or more holding members 1 are stacked, and the convex portion 11c of one holding member 1 of a pair of mutually adjacent holding members 1, 1 is fitted into the concave portion 12d of the other holding member 1, whereby three or more holding members 1 can be coupled in series. That is, depending on the application, it is possible to select whether to use one holding member 1 or to use a plurality of holding members 1 connected to each other. The number and order of the holding members 1 and the type (pore diameter, aperture ratio, material, etc.) of the filter 4 can be arbitrarily changed according to the object to be filtered, and the usability can be greatly improved.
In addition, in embodiment 2, as shown in fig. 4, since the filter 4 is disposed inside the convex portions 11c and 12c of the holding member 1, when a plurality of holding members 1 are connected in series, the filter 4 held by one holding member 1 can be prevented from being damaged by contact with the convex portions 11c and 12c of the other holding member 1.
In addition, as described with reference to fig. 5, an external thread portion may be provided on the outer peripheral surface of the convex portion 11c of one holding member 1, and an internal thread portion may be provided on the inner peripheral surface of the concave portion 12d of the other holding member 1. The convex portion 11c of the one holding member 1 and the concave portion 12d of the other holding member 1 may be configured to have inclined surfaces inclined with respect to the screwing direction of the male screw portion and the female screw portion on the side closer to the flow path than the male screw portion and the female screw portion, and to be in contact with each other by the inclined surfaces. According to this configuration, the external thread portion and the internal thread portion are screwed together, so that the one holding member 1 and the other holding member 1 can be detachably and more reliably assembled. Further, since the convex portion 11c of the one holding member 1 and the concave portion 12d of the other holding member 1 are made to contact each other by the inclined surfaces, the contact area can be increased as compared with the case where the contact is made by the surfaces orthogonal to the screwing direction. According to this configuration, even if the machining accuracy is about the same as that of the configuration in which the contact is made by the orthogonal surfaces, the portion where the convex portion 11c of one holding member 1 and the concave portion 12d of the other holding member 1 are in close contact with each other can be substantially increased, and the sealing property of the flow path of the fluid can be further improved. In this configuration, one holding member 1 corresponds to the first flow path forming member, and the through hole 12b of the one holding member 1 corresponds to the first flow path. Further, the other holding member 1 corresponds to the second flow path forming member, and the through hole 12b of the other holding member 1 corresponds to the second flow path. The filter 4 is disposed so as to cross the first flow path and the second flow path.
Further, as described with reference to fig. 5, in a state where the male screw portion and the female screw portion are screwed, a gap may be formed between the male screw portion and the other holding member 1 in the screwing direction. With these clearances, the amount of screwing of the female screw portion and the male screw portion can be further increased in a state where the inclined surfaces are in contact with each other. As a result, the contact pressure between the inclined surfaces can be increased, the portion where one holding member 1 and the other holding member 1 are in close contact can be further increased, and the sealing property of the fluid flow path can be further improved. Further, a gap may be formed between the female screw portion and one holding member 1 in the screwing direction. With this clearance, it is possible to avoid a situation in which the female screw portion comes into contact with one holding member 1 and the screwing amount cannot be increased. By checking the size of the gap, it is possible to estimate whether or not the inclined surfaces are firmly in close contact with each other, whether or not foreign matter is present between the external thread portion and the other holding member 1, or the like.
(embodiment mode 3)
Fig. 14 is a perspective view showing a schematic configuration of a filter device according to embodiment 3 of the present invention. Fig. 15 is a partially exploded perspective view of the filter apparatus of fig. 14. Fig. 16 is a cross-sectional view of the filter apparatus of fig. 14.
The filter device according to embodiment 3 is different from the filter device according to embodiment 2 in that a spacer member 5 is provided between the two holding members 1, and a cover member 6 is detachably attached to the connectors 2c, 3c of the cylindrical members 2, 3. Note that the same or similar members as those described in embodiment 1 are denoted by the same reference numerals, and redundant description thereof is omitted.
As shown in fig. 14 to 16, the spacer member 5 includes: a cylindrical portion 5 a; an annular convex portion 5c protruding toward the one holding member 1 side at a portion around the hollow portion 5 b; and a recess 5d in which a portion around the hollow portion 5b is recessed toward the one holding member 1 side. The diameter of the cylindrical portion 5a is, for example, 18 mm. The thickness (height) of the cylindrical portion 5a is, for example, 15 mm.
The convex portion 5c of the spacer member 5 has a shape that can be fitted into the concave portion 12d (see fig. 3 and 4) of the second frame member 12. That is, the convex portion 5c of the spacer member 5, the convex portion 11c of the first frame member 11, and the convex portion 3a of the cylindrical member 3 have the same shape.
The concave portion 5d of the spacer member 5 has a shape in which the convex portion 11c of the first frame member 11 and the convex portion 3a (see fig. 3 and 4) of the cylindrical member 3 can be fitted. That is, the recess 5d of the spacer member 5, the recess 12d of the second frame member 12, and the recess 2a of the cylindrical member 2 have the same shape.
Examples of the material of the separator member 5 include metals such as duralumin and aluminum, and resins such as polyethylene, polystyrene, polypropylene, polycarbonate, polyacetal, and polyetherimide.
According to embodiment 3, since the spacer member 5 is provided, the distance between the two holding members 1 and 1 (i.e., the length of the flow path) can be adjusted by an amount corresponding to the thickness of the spacer. For example, the hollow portion 5b of the spacer member 5 can be made to function as a buffer for temporarily accumulating the fluid. By combining the holding member 1 and the spacer member 5 according to the use, the usability can be further improved.
Further, according to embodiment 3, since the cover member 6 is attached to the connectors 2c and 3c of the tubular members 2 and 3, the filter device can be removed from the fluid supply device and transported in a state in which the fluid is contained in the flow path, for example. Further, by shaking the filter device in the extending direction of the flow path in a state where the cover member 6 is attached to the connectors 2c, 3c of the tubular members 2, 3, the filtering object in the fluid can be diffused and filtered. This can further improve usability.
The spacer member 5 is not limited to being disposed between the two holding members 1 and 1, and may be disposed between the cylindrical member 2 and the holding member 1 or between the cylindrical member 3 and the holding member 1.
In addition, any of the various embodiments described above can be combined as appropriate, whereby the effects each has can be achieved.
The present invention has been fully described in connection with preferred embodiments thereof with reference to the accompanying drawings, but various modifications and alterations will become apparent to those skilled in the art. It is to be understood that such changes and modifications are encompassed within the scope of the present invention as set forth in the appended claims.
Industrial applicability
The present invention can more easily observe a filtering object remaining on a filter, and is therefore useful for a filter device that filters a filtering object contained in a fluid such as a substance derived from a living organism or PM 2.5.
Description of the reference numerals
1: a holding member;
1 a: a main face;
1 b: the other main face;
2: a cylindrical member;
2 a: a recess;
2 b: a hollow portion;
2 c: connectors (luer lock type connectors);
2 d: an internal thread portion;
2 e: an inclined surface (inclined inner circumferential surface);
3: a cylindrical member;
3 a: a convex portion;
3 b: a hollow portion;
3 c: connectors (luer lock type connectors);
4: a filter;
4A: a peripheral portion;
4 a: a first curved portion;
4 b: a second curved portion;
4 c: a rib-shaped convex part;
5: an isolator member;
5 a: a cylindrical portion;
5 b: a hollow portion;
5 c: a convex portion;
5 d: a recess;
6: a cover member;
11: a first frame member;
11 a: a flat plate portion;
11 b: a through hole;
11 c: a convex portion;
11 d: a flange portion;
11 e: an inclined surface;
11 f: a front end portion;
11 g: a through hole;
11 h: an external threaded portion;
11 i: an inclined surface (inclined outer circumferential surface);
12: a second frame member;
12 a: a flat plate portion;
12 b: a through hole;
12 c: a convex portion;
12 d: a recess;
12 e: an inclined surface;
12 f: a front end portion;
12 g: a pin;
41: a metal porous film;
41a, 41 b: a main face;
41 c: a through hole.
Claims (7)
1. A filter device is provided with:
a first flow passage forming member in which a first flow passage through which a fluid flows is formed;
a second flow passage forming member in which a second flow passage through which a fluid flows is formed; and
a filter configured to filter an object to be filtered contained in the fluid by crossing the first flow path or the second flow path,
the first flow path forming member is provided with an externally threaded portion,
the second flow passage forming member is provided with an internal threaded portion,
in a state where the male thread portion and the female thread portion are screwed so that the first flow path and the second flow path communicate with each other, the first flow path forming member and the second flow path forming member are configured to have inclined surfaces inclined with respect to a screwing direction of the male thread portion and the female thread portion, respectively, on a side closer to the first flow path or the second flow path than the male thread portion and the female thread portion, and to contact each other by the inclined surfaces.
2. The filter apparatus of claim 1,
a gap is provided between the male screw portion and the second flow passage forming member in the screwing direction in a state where the male screw portion and the female screw portion are screwed.
3. The filter apparatus of claim 1,
in a state where the male screw portion and the female screw portion are screwed, a gap is provided between the female screw portion and the first flow passage forming member in the screwing direction.
4. The filter apparatus of claim 2,
in a state where the male screw portion and the female screw portion are screwed, a gap is provided between the female screw portion and the first flow passage forming member in the screwing direction.
5. A filter device according to any one of claims 1 to 4,
the filter includes a metal porous membrane for filtering a substance derived from a living organism as the object to be filtered.
6. A filter device according to any one of claims 1 to 4,
at least one of the first flow passage forming member and the second flow passage forming member is a holding member that holds an outer peripheral portion of the filter.
7. The filter apparatus of claim 5,
at least one of the first flow passage forming member and the second flow passage forming member is a holding member that holds an outer peripheral portion of the filter.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016158018 | 2016-08-10 | ||
| JP2016-158018 | 2016-08-10 | ||
| PCT/JP2017/025936 WO2018030081A1 (en) | 2016-08-10 | 2017-07-18 | Filter device |
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| Publication Number | Publication Date |
|---|---|
| CN109414631A CN109414631A (en) | 2019-03-01 |
| CN109414631B true CN109414631B (en) | 2021-01-01 |
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| CN201780041259.2A Active CN109414631B (en) | 2016-08-10 | 2017-07-18 | Filter device |
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| US (1) | US10675566B2 (en) |
| JP (1) | JP6428972B2 (en) |
| CN (1) | CN109414631B (en) |
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| JP6566146B2 (en) * | 2016-11-18 | 2019-08-28 | 株式会社村田製作所 | Cell culture medium recovery filter unit, cell culture medium recovery method, and cell culture medium recovery kit |
| TWM610191U (en) * | 2019-10-02 | 2021-04-11 | 普生股份有限公司 | Microfilter and microfiltration unit |
| US20210387146A1 (en) * | 2020-06-11 | 2021-12-16 | Duke University | Collection of cells from biological fluid |
| WO2022080299A1 (en) * | 2020-10-14 | 2022-04-21 | 日本板硝子株式会社 | Portable filtration and collection device |
| CN113426207B (en) * | 2021-06-03 | 2023-04-07 | 成都易态科技有限公司 | Connecting structure for assembling filter element |
| WO2024180932A1 (en) * | 2023-03-02 | 2024-09-06 | 株式会社村田製作所 | Filter and filter device |
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| CN102890049A (en) * | 2011-07-19 | 2013-01-23 | 希森美康株式会社 | Flow cytometer and analyzer |
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| CA1198063A (en) * | 1981-09-16 | 1985-12-17 | Richard A. Leoncavallo | Reusable filter unit with recoverable filter membrane |
| US4678576A (en) | 1981-09-16 | 1987-07-07 | Nalge Company | Reusable filter unit with recoverable filter membrane |
| JPS6173054A (en) * | 1984-09-17 | 1986-04-15 | メデイカル テクノロジ− コ−ポレ−シヨン | Small bottle for adjusting sample |
| JPH0225006U (en) * | 1988-08-05 | 1990-02-19 | ||
| US5139031A (en) * | 1989-09-18 | 1992-08-18 | La Mina Ltd. | Method and device for cytology and microbiological testing |
| JPH0889720A (en) * | 1994-09-19 | 1996-04-09 | Horiba Ltd | Filter device |
| JPH08304370A (en) * | 1995-04-28 | 1996-11-22 | Shimadzu Corp | Piping connecting structure |
| AU2001229358A1 (en) * | 2000-01-14 | 2001-07-24 | Pall Corporation | Filter for gas analysis |
| JP2007304016A (en) | 2006-05-12 | 2007-11-22 | Sekisui Chem Co Ltd | Blood separation apparatus |
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2017
- 2017-07-18 CN CN201780041259.2A patent/CN109414631B/en active Active
- 2017-07-18 JP JP2018532893A patent/JP6428972B2/en active Active
- 2017-07-18 WO PCT/JP2017/025936 patent/WO2018030081A1/en active Application Filing
-
2018
- 2018-10-30 US US16/174,711 patent/US10675566B2/en active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2018030081A1 (en) | 2018-02-15 |
| CN109414631A (en) | 2019-03-01 |
| JP6428972B2 (en) | 2018-11-28 |
| US10675566B2 (en) | 2020-06-09 |
| US20190060799A1 (en) | 2019-02-28 |
| JPWO2018030081A1 (en) | 2018-12-06 |
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