JP6494112B2 - アストリンとラプターの相互作用調節因子、及びその癌治療での用途 - Google Patents

アストリンとラプターの相互作用調節因子、及びその癌治療での用途 Download PDF

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JP6494112B2
JP6494112B2 JP2015552068A JP2015552068A JP6494112B2 JP 6494112 B2 JP6494112 B2 JP 6494112B2 JP 2015552068 A JP2015552068 A JP 2015552068A JP 2015552068 A JP2015552068 A JP 2015552068A JP 6494112 B2 JP6494112 B2 JP 6494112B2
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astrin
raptor
cells
cell
binding
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JP2016511822A5 (cg-RX-API-DMAC7.html
JP2016511822A (ja
Inventor
セディーク，カトリン
ホルツヴァルト，ビルギット
バウマイスター，ラルフ
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Albert Ludwigs Universitaet Freiburg
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Albert Ludwigs Universitaet Freiburg
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]

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  • Health & Medical Sciences (AREA)
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  • Molecular Biology (AREA)
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  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
JP2015552068A 2013-01-11 2014-01-13 アストリンとラプターの相互作用調節因子、及びその癌治療での用途 Expired - Fee Related JP6494112B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13151022.4A EP2755027B1 (en) 2013-01-11 2013-01-11 Modulators of the interaction of astrin and raptor, and uses thereof in cancer therapy
EP13151022.4 2013-01-11
PCT/EP2014/050460 WO2014108532A1 (en) 2013-01-11 2014-01-13 Modulators of the interaction of astrin and raptor, and uses thereof in cancer therapy

Publications (3)

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JP2016511822A JP2016511822A (ja) 2016-04-21
JP2016511822A5 JP2016511822A5 (cg-RX-API-DMAC7.html) 2017-02-23
JP6494112B2 true JP6494112B2 (ja) 2019-04-03

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JP2015552068A Expired - Fee Related JP6494112B2 (ja) 2013-01-11 2014-01-13 アストリンとラプターの相互作用調節因子、及びその癌治療での用途

Country Status (5)

Country Link
US (1) US10041933B2 (cg-RX-API-DMAC7.html)
EP (1) EP2755027B1 (cg-RX-API-DMAC7.html)
JP (1) JP6494112B2 (cg-RX-API-DMAC7.html)
ES (1) ES2588778T3 (cg-RX-API-DMAC7.html)
WO (1) WO2014108532A1 (cg-RX-API-DMAC7.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11237168B2 (en) 2019-06-26 2022-02-01 St. Jude Children's Research Hospital Method for identifying modulators of G3BP activity
CN110476877A (zh) * 2019-08-15 2019-11-22 上海交通大学医学院附属瑞金医院 一种β细胞中特异性Raptor敲除同时GFP示踪的小鼠的制备方法
CN113125747B (zh) * 2021-03-15 2022-06-14 天津医科大学 一种isPLA-Seq的高通量检测蛋白质相互作用的方法和试剂盒及其应用

Also Published As

Publication number Publication date
US10041933B2 (en) 2018-08-07
EP2755027A1 (en) 2014-07-16
WO2014108532A1 (en) 2014-07-17
HK1199930A1 (en) 2015-07-24
JP2016511822A (ja) 2016-04-21
US20150355166A1 (en) 2015-12-10
ES2588778T3 (es) 2016-11-04
EP2755027B1 (en) 2016-06-01

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