JP6470748B2 - 対象の表面をモニターし、処置するための化合物、システムおよび方法 - Google Patents

対象の表面をモニターし、処置するための化合物、システムおよび方法 Download PDF

Info

Publication number
JP6470748B2
JP6470748B2 JP2016525348A JP2016525348A JP6470748B2 JP 6470748 B2 JP6470748 B2 JP 6470748B2 JP 2016525348 A JP2016525348 A JP 2016525348A JP 2016525348 A JP2016525348 A JP 2016525348A JP 6470748 B2 JP6470748 B2 JP 6470748B2
Authority
JP
Japan
Prior art keywords
group
porphyrin
therapeutic agent
oxygen
unsubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2016525348A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016531168A (ja
JP2016531168A5 (enExample
Inventor
エヴァンズ、コナー、エル
アピオウ、ガブリエラ
ニコラス、アレクサンダー、ジェイ
ルーサキス、エマヌエル
リ、ゾンギ
Original Assignee
ザ ジェネラル ホスピタル コーポレイション
ザ ジェネラル ホスピタル コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2013/049847 external-priority patent/WO2014011724A1/en
Application filed by ザ ジェネラル ホスピタル コーポレイション, ザ ジェネラル ホスピタル コーポレイション filed Critical ザ ジェネラル ホスピタル コーポレイション
Publication of JP2016531168A publication Critical patent/JP2016531168A/ja
Publication of JP2016531168A5 publication Critical patent/JP2016531168A5/ja
Application granted granted Critical
Publication of JP6470748B2 publication Critical patent/JP6470748B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0015Phosphorescence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14556Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases by fluorescence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683Means for maintaining contact with the body
    • A61B5/6832Means for maintaining contact with the body using adhesives
    • A61B5/6833Adhesive patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/56Wetness-indicators or colourants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6408Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2016525348A 2013-07-10 2014-06-13 対象の表面をモニターし、処置するための化合物、システムおよび方法 Active JP6470748B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/US2013/049847 WO2014011724A1 (en) 2012-07-10 2013-07-10 System and method for monitoring and treating a surface of a subject
USPCT/US2013/049847 2013-07-10
PCT/US2014/042377 WO2015006015A1 (en) 2013-07-10 2014-06-13 Compounds, systems, and methods for monitoring and treating a surface of a subject

Publications (3)

Publication Number Publication Date
JP2016531168A JP2016531168A (ja) 2016-10-06
JP2016531168A5 JP2016531168A5 (enExample) 2017-07-27
JP6470748B2 true JP6470748B2 (ja) 2019-02-13

Family

ID=52280743

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016525348A Active JP6470748B2 (ja) 2013-07-10 2014-06-13 対象の表面をモニターし、処置するための化合物、システムおよび方法

Country Status (4)

Country Link
EP (1) EP3019854B1 (enExample)
JP (1) JP6470748B2 (enExample)
ES (1) ES2860675T3 (enExample)
WO (1) WO2015006015A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6321004B2 (ja) 2012-07-10 2018-05-09 ザ ジェネラル ホスピタル コーポレイション 対象のモニタリングと表面処理のためのシステムおよび方法
JP7109377B2 (ja) 2016-05-13 2022-07-29 ザ ジェネラル ホスピタル コーポレイション 光経皮酸素モニタリングのシステム及び方法
US11202860B2 (en) * 2018-06-06 2021-12-21 International Business Machines Corporation Controlled drug delivery in point-of-care drug delivery system based on real-time monitoring with integrated sensor
WO2023178034A1 (en) * 2022-03-14 2023-09-21 Hollister Incorporated System and method for detecting oxygen for prediction, detection, mitigation and/or prevention of peristomal skin injury

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837865A (en) * 1993-10-15 1998-11-17 Trustees Of The University Of Pennsylvania Phosphorescent dendritic macromolecular compounds for imaging tissue oxygen
JP4118338B2 (ja) * 1996-07-22 2008-07-16 ノバルティス アクチエンゲゼルシャフト プラチナまたはパラジウムベンゾポルフィリンおよびプラチナまたはパラジウムシクロヘキセンポルフィリンの製造法、中間体およびプラチナまたはパラジウムシクロヘキセンポルフィリンを含む酸素センサー
US20030203888A1 (en) * 2001-06-06 2003-10-30 Boyle Ross William Chromophores
JP3931236B2 (ja) * 2003-07-09 2007-06-13 独立行政法人情報通信研究機構 基板上のポテンシャル特異点を用いたナノデバイスの製造方法
WO2007081811A2 (en) * 2006-01-04 2007-07-19 The Trustees Of The University Of Pennsylvania Oxygen sensor for internal monitoring of tissue oxygen in vivo
EP1808627A1 (fr) 2006-01-12 2007-07-18 Luxembourg Patent Company S.A. Dispositif indicateur de l'état d'ouverture d'une vanne
JP2009162871A (ja) * 2007-12-28 2009-07-23 Fujifilm Corp 感光性組成物、フォトスペーサー及びフォトスペーサーの製造方法、保護膜、着色パターン、表示装置用基板、並びに表示装置
WO2012033916A1 (en) * 2010-09-08 2012-03-15 Southern Illinois University Edwardsville Method for treating chronic pain
JP6321004B2 (ja) * 2012-07-10 2018-05-09 ザ ジェネラル ホスピタル コーポレイション 対象のモニタリングと表面処理のためのシステムおよび方法

Also Published As

Publication number Publication date
EP3019854A4 (en) 2016-12-14
JP2016531168A (ja) 2016-10-06
EP3019854A1 (en) 2016-05-18
WO2015006015A1 (en) 2015-01-15
EP3019854B1 (en) 2021-01-06
ES2860675T3 (es) 2021-10-05

Similar Documents

Publication Publication Date Title
US12059481B2 (en) Compounds, systems, and methods for monitoring and treating a surface of a subject
Yang et al. Recent progress in microneedles‐mediated diagnosis, therapy, and theranostic systems
KR102373982B1 (ko) 생-감지 분석물의 생체 내 보호를 위한 약물 용출
JP6470748B2 (ja) 対象の表面をモニターし、処置するための化合物、システムおよび方法
CN1976627A (zh) 附着皮肤的传感器装置
CA2777481A1 (en) Methods and devices for self adjusting phototherapeutic intervention
US9789206B2 (en) Compounds, systems, and methods for monitoring and treating a surface of a subject
JP2017523863A (ja) 連続検体センサー
EP2767824B1 (en) Method and device for detecting analytes
Zhou et al. Aggregation-induced emission luminogen based wearable visible-light penetrator for deep photodynamic therapy
JP7109377B2 (ja) 光経皮酸素モニタリングのシステム及び方法
WO2021097274A1 (en) Identification of degradative species
EP3840637B1 (en) Mediated drug release for reducing in vivo analyte indicator degradation
US11826143B2 (en) Reduction of in vivo analyte signal degradation using multiple metals
WO2024167882A2 (en) Reduction of in vivo analyte signal degradation using multiple metals
Li et al. Nanoparticle Oxygen Sensing in Skin

Legal Events

Date Code Title Description
RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20160323

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170612

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20170612

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20180130

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20180410

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20180705

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20180822

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180827

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20190108

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20190118

R150 Certificate of patent or registration of utility model

Ref document number: 6470748

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250