JP2016531168A5 - - Google Patents
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- Publication number
- JP2016531168A5 JP2016531168A5 JP2016525348A JP2016525348A JP2016531168A5 JP 2016531168 A5 JP2016531168 A5 JP 2016531168A5 JP 2016525348 A JP2016525348 A JP 2016525348A JP 2016525348 A JP2016525348 A JP 2016525348A JP 2016531168 A5 JP2016531168 A5 JP 2016531168A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- porphyrin
- unsubstituted
- nanometers
- atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000004032 porphyrins Chemical class 0.000 claims 26
- 238000000034 method Methods 0.000 claims 24
- 125000004429 atom Chemical group 0.000 claims 15
- 125000000217 alkyl group Chemical group 0.000 claims 7
- 150000001875 compounds Chemical class 0.000 claims 6
- 125000001425 triazolyl group Chemical group 0.000 claims 6
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical group [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims 4
- 125000004448 alkyl carbonyl group Chemical group 0.000 claims 4
- 125000000304 alkynyl group Chemical group 0.000 claims 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 4
- WHUUTDBJXJRKMK-VKHMYHEASA-L glutamate group Chemical group N[C@@H](CCC(=O)[O-])C(=O)[O-] WHUUTDBJXJRKMK-VKHMYHEASA-L 0.000 claims 4
- 229910052751 metal Inorganic materials 0.000 claims 4
- 239000002184 metal Substances 0.000 claims 4
- 239000001301 oxygen Substances 0.000 claims 4
- 229910052760 oxygen Inorganic materials 0.000 claims 4
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical group [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 4
- 239000001257 hydrogen Substances 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 125000002568 propynyl group Chemical group [*]C#CC([H])([H])[H] 0.000 claims 3
- SYQNQPHXKWWZFS-YFKPBYRVSA-N (4s)-4-amino-5-ethoxy-5-oxopentanoic acid Chemical group CCOC(=O)[C@@H](N)CCC(O)=O SYQNQPHXKWWZFS-YFKPBYRVSA-N 0.000 claims 2
- MHIITNFQDPFSES-UHFFFAOYSA-N 25,26,27,28-tetrazahexacyclo[16.6.1.13,6.18,11.113,16.019,24]octacosa-1(25),2,4,6,8(27),9,11,13,15,17,19,21,23-tridecaene Chemical class N1C(C=C2C3=CC=CC=C3C(C=C3NC(=C4)C=C3)=N2)=CC=C1C=C1C=CC4=N1 MHIITNFQDPFSES-UHFFFAOYSA-N 0.000 claims 2
- 125000003342 alkenyl group Chemical group 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 125000004093 cyano group Chemical group *C#N 0.000 claims 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims 2
- 125000005843 halogen group Chemical group 0.000 claims 2
- 125000001072 heteroaryl group Chemical group 0.000 claims 2
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- 229910052763 palladium Inorganic materials 0.000 claims 2
- 229910052697 platinum Inorganic materials 0.000 claims 2
- 230000002194 synthesizing effect Effects 0.000 claims 2
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims 1
- 239000000412 dendrimer Substances 0.000 claims 1
- 229920000736 dendritic polymer Polymers 0.000 claims 1
- 235000013922 glutamic acid Nutrition 0.000 claims 1
- 239000004220 glutamic acid Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- -1 porphyrin compound Chemical class 0.000 claims 1
- 125000006253 t-butylcarbonyl group Chemical group [H]C([H])([H])C(C(*)=O)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2013/049847 WO2014011724A1 (en) | 2012-07-10 | 2013-07-10 | System and method for monitoring and treating a surface of a subject |
| USPCT/US2013/049847 | 2013-07-10 | ||
| PCT/US2014/042377 WO2015006015A1 (en) | 2013-07-10 | 2014-06-13 | Compounds, systems, and methods for monitoring and treating a surface of a subject |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016531168A JP2016531168A (ja) | 2016-10-06 |
| JP2016531168A5 true JP2016531168A5 (enExample) | 2017-07-27 |
| JP6470748B2 JP6470748B2 (ja) | 2019-02-13 |
Family
ID=52280743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016525348A Active JP6470748B2 (ja) | 2013-07-10 | 2014-06-13 | 対象の表面をモニターし、処置するための化合物、システムおよび方法 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP3019854B1 (enExample) |
| JP (1) | JP6470748B2 (enExample) |
| ES (1) | ES2860675T3 (enExample) |
| WO (1) | WO2015006015A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10016164B2 (en) | 2012-07-10 | 2018-07-10 | The General Hospital Corporation | System and method for monitoring and treating a surface of a subject |
| EP3454746B1 (en) | 2016-05-13 | 2024-02-07 | The General Hospital Corporation | Systems and methods of optical transcutaneous oxygenation monitoring |
| US11202860B2 (en) * | 2018-06-06 | 2021-12-21 | International Business Machines Corporation | Controlled drug delivery in point-of-care drug delivery system based on real-time monitoring with integrated sensor |
| WO2023178034A1 (en) * | 2022-03-14 | 2023-09-21 | Hollister Incorporated | System and method for detecting oxygen for prediction, detection, mitigation and/or prevention of peristomal skin injury |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5837865A (en) * | 1993-10-15 | 1998-11-17 | Trustees Of The University Of Pennsylvania | Phosphorescent dendritic macromolecular compounds for imaging tissue oxygen |
| WO1998003512A1 (en) * | 1996-07-22 | 1998-01-29 | Novartis Ag | Process for the preparation of platinum or palladium benzoporphyrins and platinum or palladium cyclohexenoporphyrins, intermediates, and an oxygen sensor comprising platinum or palladium cyclohexenoporphyrin |
| US20030203888A1 (en) * | 2001-06-06 | 2003-10-30 | Boyle Ross William | Chromophores |
| JP3931236B2 (ja) * | 2003-07-09 | 2007-06-13 | 独立行政法人情報通信研究機構 | 基板上のポテンシャル特異点を用いたナノデバイスの製造方法 |
| US9044179B2 (en) * | 2006-01-04 | 2015-06-02 | The Trustees Of The University Of Pennslyvania | Oxygen sensor for internal monitoring of tissue oxygen in vivo |
| EP1808627A1 (fr) | 2006-01-12 | 2007-07-18 | Luxembourg Patent Company S.A. | Dispositif indicateur de l'état d'ouverture d'une vanne |
| JP2009162871A (ja) * | 2007-12-28 | 2009-07-23 | Fujifilm Corp | 感光性組成物、フォトスペーサー及びフォトスペーサーの製造方法、保護膜、着色パターン、表示装置用基板、並びに表示装置 |
| WO2012033916A1 (en) * | 2010-09-08 | 2012-03-15 | Southern Illinois University Edwardsville | Method for treating chronic pain |
| US10016164B2 (en) * | 2012-07-10 | 2018-07-10 | The General Hospital Corporation | System and method for monitoring and treating a surface of a subject |
-
2014
- 2014-06-13 WO PCT/US2014/042377 patent/WO2015006015A1/en not_active Ceased
- 2014-06-13 EP EP14822888.5A patent/EP3019854B1/en active Active
- 2014-06-13 JP JP2016525348A patent/JP6470748B2/ja active Active
- 2014-06-13 ES ES14822888T patent/ES2860675T3/es active Active
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