JP6431633B1 - Wet tissue packaging - Google Patents

Abstract

To provide a laminated film for wet tissue packaging capable of maintaining a desired hermeticity even when it is placed in a high temperature environment exceeding the normal temperature range for a long time after being sealed by heat sealing. A laminated film 2 for packaging wet tissue includes a first resin film 5, an aluminum foil 6, and a second resin film 7 having heat sealing properties, which are laminated in this order. The second resin film 7 is an unstretched polypropylene film, a heat-resistant unstretched polypropylene film, or a heat-resistant linear low-density polyethylene film. [Selection] Figure 4

Description

  The present invention relates to a laminated film for wet tissue packaging, and a wet tissue package that can be stored at a high temperature above the normal environment.

  2. Description of the Related Art Conventionally, a wet tissue in which a chemical material is impregnated in a fiber material such as a nonwoven fabric is known. Wet tissue is used for wiping human fingers, skin, articles and the like, and its use is spreading due to the property of creating a sanitary environment in a water-poor situation. In addition, use and storage in harsh conditions that are not seen in the daily environment of Japan, such as extremely cold environments and scorching environments, have been demanded.

  In order to avoid drying, it is necessary to store the wet tissue in a container having a sealing property. In this state, a wet tissue wound in a roll shape is packed in a cylindrical container, or a wet tissue folded flat is laminated. A bag-like package (see, for example, Patent Document 1) is widely used. In particular, the latter is easy to downsize and has excellent portability.

Japanese Patent No. 6212359

  Wet tissue is a product category of cosmetics that wipes sundry goods and the human body, and is manufactured on the assumption that it is used in a room temperature environment up to 40 ° C. A bag-like package generally retains its sealing property by heat-sealing a resin film, an aluminum vapor-deposited resin film, or a laminate of a resin film and an aluminum foil, but its contents when placed in a high-temperature environment The internal pressure rises due to vaporization and the heat-sealed part peels and bursts, heat contracts due to overheating of the resin film itself, or the interlayer peels due to the difference in heat denaturation between the resin film and the aluminum foil (hereinafter, These phenomena are collectively referred to as “delamination”.) Many cases are unable to withstand high-temperature storage. In particular, this tendency is remarkable in the case of long-term storage in a vehicle for in-vehicle use.

  Therefore, the present invention provides a laminated film for wet tissue packaging capable of maintaining a desired hermeticity even when placed in a high temperature environment exceeding a normal temperature range for a long time after being sealed by heat sealing, and a wet film An object is to provide a tissue package.

  In the present invention, a first resin film, an aluminum foil, and a second resin film having heat sealing properties are laminated in this order, and the second resin film includes an unstretched polypropylene film and a heat-resistant unstretched polypropylene. Provided is a laminated film for wet tissue packaging which is a film or a heat-resistant linear low-density polyethylene film.

  The laminated film has strength for wet tissue packaging, is excellent in liquid and gas barrier properties, and is excellent in heat sealability. Therefore, even when the wet tissue is sealed by heat sealing and then placed in a high-temperature environment exceeding the normal temperature range for a long time, the desired sealing performance can be maintained.

  Here, the first resin film is a polyethylene terephthalate film, and the first resin film, the aluminum foil, and the second resin film are preferably laminated by dry lamination. When laminated by dry lamination, the heat resistance is high, and the peel resistance between the films is improved.

  The present invention also includes a wet tissue in which a base material is impregnated with a drug, and the laminated film for wet tissue packaging, wherein the laminated film for wet tissue packaging faces the second resin film side inward. A wet tissue packaging body that surrounds the wet tissue and that the surfaces of the second resin film faces each other and are heat sealed to each other so that the wet tissue is sealed with a laminated film for wet tissue packaging. provide.

  In this package, the laminated film has strength for wet tissue packaging, is excellent in liquid and gas barrier properties, and is excellent in heat sealability. Therefore, the package formed by sealing the wet tissue by heat sealing can prevent delamination from occurring in the heat seal portion even when placed in a high temperature environment exceeding the normal temperature range for a long time. And a desired sealing property can be maintained.

In this package, the ratio of the volume value (unit: ml) of the drug to the area value (unit: cm ² ) on the second resin film side excluding the heat-sealed portion is 0.10 to 0.00. 50 is preferable. The ratio of the weight value (unit: g) of the wet tissue to the area value (unit: cm ² ) on the second resin film side excluding the heat-sealed portion is 0.10 to 0.50. Preferably there is. In high temperature environments, the drug evaporates in the package and the internal pressure rises, but if this ratio is satisfied, there is room in the package to further prevent delamination from occurring in the heat seal area. Can do.

  It is preferable that the laminated film for wet tissue packaging which comprises the package body is provided with the cover material which has an opening part for taking out a wet tissue, and covers an opening part so that opening and closing is possible. According to this, it is easy to take out the wet tissue, and it is possible to prevent the wet tissue from drying by closing after opening.

  The drug is preferably a non-alcohol drug. Non-alcoholic drugs are those in which the blending ratio of ethanol and polyhydric alcohol is suppressed. Therefore, many non-alcoholic drugs are difficult to evaporate even in a high-temperature environment, and therefore the increase in the internal pressure of the package can be suppressed.

  The wet tissue package may be for vehicle use. It is generally known that the interior of a vehicle is susceptible to overheating of the motor and the outside air environment in general, and the interior of the vehicle rises to 80 ° C. due to parking on a roofless road in summer. Therefore, the wet tissue package of the present invention that can sufficiently withstand temperatures exceeding the normal temperature range is particularly excellent for in-vehicle use.

  According to the present invention, a laminated film for wet tissue packaging that can maintain a desired hermeticity even when placed in a high-temperature environment exceeding the normal temperature range for a long time after sealing by heat sealing, and A wet tissue package can be provided.

It is a perspective view of a wet tissue package. It is a perspective view of the back side of the wet tissue package shown in FIG. It is sectional drawing in the III-III line of FIG. It is sectional drawing which shows the laminated structure of the laminated | multilayer film for wet tissue packaging. It is a perspective view of the wet tissue package of other embodiment.

  DESCRIPTION OF EXEMPLARY EMBODIMENTS Hereinafter, preferred embodiments of the invention will be described in detail with reference to the drawings. In addition, in each figure, the same code | symbol is attached | subjected to the same part or an equivalent part, and the overlapping description is abbreviate | omitted. Further, for convenience of explanation, there is a part in which the dimensional ratio is exaggerated.

<Wet tissue packaging>
As shown in FIGS. 1 to 3, the wet tissue packaging body (hereinafter simply referred to as “packaging body”) 1 of the present embodiment is a laminated film for wet tissue packaging (hereinafter simply referred to as “lamination film”). 2 is formed by sealing the wet tissue 3. More specifically, the package 1 surrounds the rectangular laminated film 2 so as to wind the wet tissue 3, and the end portions are heat-sealed to form the center seal portion 2 </ b> A. At the same time, the end seal portions 2B and 2B are formed by heat-sealing both end portions in the direction in which the center seal portion 2A extends in a direction orthogonal to the direction. The wet tissue 3 is hermetically accommodated by these heat seals, and the package 1 has a so-called pillow-type flat plate shape. The center seal portion 2A is positioned so as to cross the center of one flat surface (see FIG. 2).

  In the flat package 1, an opening 2 </ b> C for taking out the wet tissue 3 is provided on the surface that does not have the center seal portion 2 </ b> A. And the lid | cover material 4 which has a magnitude | size which can cover the whole opening part 2C, and covers the whole opening part 2C is provided. The lid member 4 is a tongue-like resin film member partly adhered to the outer surface of the laminated film 2, and adheres to the surface of the laminated film 2 in a portion not adhered to the surface of the laminated film 2. An adhesive is provided. The opening 2C can be opened and closed by repeatedly sticking to the surface of the laminated film 2 with this adhesive. Moreover, since it has prevented the lid | cover material 4 from isolate | separating from the surface of the laminated | multilayer film 2 by having the part adhere | attached on the surface of the laminated | multilayer film 2, the lid | cover material 4 is hard to dissipate.

  The wet tissue 3 is formed by impregnating a base material such as a nonwoven fabric made of rayon, polyester or the like with a drug. About 10 to 30 sheets of the wet tissue 3 are folded flat and accommodated inside the package 1. (See FIG. 3). Examples of the agent to be impregnated include cleaning agents, moisturizing agents, preservatives, and fragrances, and it is preferable to select non-alcohol agents for all. Many non-alcoholic drugs are difficult to evaporate even in a high-temperature environment, and the increase in internal pressure of the package 1 can be suppressed. Here, the non-alcohol drug does not contain ethanol and is obtained by reducing the blending ratio of polyhydric alcohol or the like.

  The drug is preferably in a liquid (chemical solution) state so as to be easily impregnated. The drug may be impregnated with the stock solution of the active ingredient as it is, or may be impregnated in a state diluted (or dissolved) with another solvent such as water. Here, the liquid immediately before impregnation is called a chemical solution.

The amount of the drug (or chemical solution) to be impregnated is the value of the volume of the drug (unit: ml) with respect to the area value (unit: cm ² ) on the inner surface side excluding the heat-sealed portion of the laminated film 2. The ratio is preferably 0.10 to 0.50 (unit: ml / cm ² ), and more preferably 0.20 to 0.40. The lower limit of this numerical range may be 0.15, 0.22, 0.25, 0.30, 0.35, and the upper limit is 0.45, 0.37, 0.35, 0.30, 0. .25 and 0.20, and these numerical values can be combined appropriately to form a numerical range. In a high temperature environment, the drug may evaporate in the package and the internal pressure may increase. However, if this ratio is satisfied, there is room in the package 1, so the center seal portion 2A or the end seal portions 2B and 2B It is possible to further prevent delamination from occurring. In addition, when calculating the value of the area of the inner surface side of the laminated film 2 here, it is assumed that the opening 2C is closed and incorporated in the area.

In addition, the amount of the drug (or chemical solution) to be impregnated is the weight of the drug and the weight of the substrate with respect to the value of the area on the inner surface side excluding the heat-sealed portion of the laminated film 2 (unit: cm ² ) The ratio of the total value (that is, the weight value of wet tissue (unit: g)) is preferably 0.10 to 0.75 (unit is g / cm ² ), and further 0.20 to 0.00. 60 is more preferable. The lower limit of this numerical range may be 0.30, 0.35, 0.40, 0.45, 0.50, 0.55, and the upper limit is 0.70, 0.65, 0.55, 0. .50, and these numerical values can be appropriately combined to form a numerical range. In a high temperature environment, the drug may evaporate in the package and the internal pressure may increase. However, if this ratio is satisfied, there is room in the package 1, so the center seal portion 2A or the end seal portions 2B and 2B It is possible to further prevent delamination from occurring. In addition, when calculating the value of the area of the inner surface side of the laminated film 2 here, it is assumed that the opening 2C is closed and incorporated in the area.

<Laminated film>
As shown in FIG. 4, the laminated film 2 is formed by laminating a first resin film 5, an aluminum foil 6, and a second resin film 7 having heat sealing properties in this order. These films are preferably laminated by dry lamination, and as an adhesive (not shown in FIG. 4) for bonding the layers, heat resistance and adhesion strength between layers (peeling resistance) From the viewpoint of excellent properties, a heat-resistant adhesive that can withstand a temperature of 120 ° C. or higher is preferable, and an acrylic adhesive or a polyester adhesive is preferable. The total thickness of the laminated film 2 is preferably 50 to 70 μm.

  The first resin film 5 is a film that forms a layer facing the outer surface when the packaging body 1 is configured. Examples of the material of the first resin film 5 include polyethylene terephthalate (PET), biaxially stretched polypropylene (OPP), and nylon. Of these, polyethylene terephthalate is preferable from the viewpoint of heat resistance and strength. The thickness of the first resin film 5 is preferably 10 to 20 μm.

  The thickness of the aluminum foil 6 should just be the thickness which can ensure the barrier | blocking property of gas and a liquid, and it is preferable that it is 5-10 micrometers.

  The second resin film 7 is a film that forms a layer facing the inner surface when the package 1 is configured. Examples of the material of the second resin film 7 include unstretched polypropylene (CPP), heat-resistant unstretched polypropylene (heat-resistant CPP), and heat-resistant linear low-density polyethylene (heat-resistant LLDPE). Of these, unstretched polypropylene or heat-resistant linear low-density polyethylene is preferable, and heat-resistant linear low-density polyethylene is particularly preferable in that it is difficult to cause delamination in a high-temperature environment. The heat resistant temperature of the second resin film 7 is preferably 120 ° C. or higher, more preferably 130 ° C. or higher, and still more preferably 140 ° C. or higher. The thickness of the second resin film 7 is preferably 30 to 70 μm.

  The CPP and the heat-resistant CPP are preferably copolymers using propylene as a main raw material, and are preferably propylene / ethylene copolymers. The propylene / ethylene copolymer is preferably a block copolymer.

  It is preferable that the heat shrinkage (120 ° C., 30 minutes, measured in accordance with JIS K6782) of the CPP film and the heat-resistant CPP film as the second resin film 7 is 2.0% or less in both the vertical direction and the horizontal direction. 1.6% or less is more preferable, and 1.0% or less is still more preferable.

  The tensile modulus (measured according to JIS K7127) of the CPP film is preferably 450 to 650 MPa, more preferably 500 to 600 MPa in both the longitudinal direction and the transverse direction. The tensile elastic modulus (measured according to JIS K7127) of the heat-resistant CPP film is preferably 250 to 500 MPa in both the longitudinal direction and the transverse direction, and more preferably 300 to 450 MPa.

  Examples of the CPP film include “Pyrene Film-CTP1128” (trade name) manufactured by Toyobo Co., Ltd., and examples of the heat-resistant CPP film include “Pyrene Film-CTP1153” (trade name) manufactured by Toyobo Co., Ltd.

The heat-resistant LLDPE is preferably a copolymer having ethylene (ethene, CH ₂ ═CH ₂ ) as a main raw material, and preferably contains a structural unit having 6 or more carbon atoms as a comonomer unit to be copolymerized. In particular, ethylene and α-olefin are preferably copolymerized, and structural units having 6 or more carbon atoms include 1-hexene (C6), 4-methylpentene (C6), 1-octene (C8 ) And the like.

  The heat-resistant LLDPE film as the second resin film 7 is preferably an unstretched film, and the heat shrinkage rate (90 ° C., 30 minutes, measured in accordance with JIS K6782) is 1.0 in both the vertical and horizontal directions. % Or less, more preferably 0.7% or less, and even more preferably 0.5% or less.

  The tensile modulus (measured according to JIS K7127) of the heat-resistant LLDPE film is preferably 150 to 300 MPa, more preferably 200 to 300 MPa in both the longitudinal direction and the transverse direction.

  Examples of the heat-resistant LLDPE film include “Rix film LIX-1 L6101” (trade name) manufactured by Toyobo Co., Ltd.

  The package 1 produced using such a laminated film 2 is excellent in storability in a low temperature environment and a high temperature environment. Specifically, heat-seal delamination is possible even when stored for a long time in various temperature environments such as cold regions where temperatures below freezing continue, environments where boilers and motors operate, and interiors where the temperature is higher than the outside air. Does not occur, or even if it does occur, there is no problem in using the wet tissue 3. Conventional wet tissue is assumed to be used in a normal temperature environment up to 40 ° C., and there is a large difference in shelf life in a high temperature range (for example, 7 days at 80 ° C.) and a high and low temperature. Almost no consideration has been given to storability in an environment (for example, an environment where a temperature below freezing point and a temperature of 50 ° C. or higher is repeated). The package 1 produced using the laminated film 2 of the present embodiment can be used for in-vehicle use. The inside of the vehicle has a large temperature change and is likely to be hotter than the outside air in summer. Therefore, it is suitable as an application of the package 1 of the present embodiment. Here, “in-vehicle use” is a concept including loading in a vehicle in anticipation of continuous storage in units of days to weeks, months, or years, for example.

<Method for producing wet tissue package>
The manufacturing method of the package 1 is as follows. First, a laminated wet tissue 3 and a laminated film 2 on which an opening 2C and a lid 4 are formed are prepared. The wet tissue 3 is surrounded in a cylindrical shape by a laminated film 2 having a predetermined width. At this time, the second resin film 7 side is set to face the wet tissue 3 side. And in the joint of the laminated | multilayer film 2, it heat-seals in the state which faced the 2nd resin film 7 side, and forms the center seal | sticker part 2A. Next, both cylindrical end portions are heat-sealed to form end seal portions 2B and 2B. By these heat seals, the package 1 in which the wet tissue 3 is sealed can be manufactured. Note that heat sealing may be performed in two stages of preheating and main heat.

  The heat seal temperature should just be a temperature which can fuse | melt the 2nd resin film mutually, and 120-200 degreeC is preferable. When dividing into two stages of preheating and main heating, it is preferable that the temperature of the main heating is higher by 10 to 30 ° C. than the temperature of the preheating.

  The preferred embodiment of the present invention has been described above, but the present invention is not limited to the above embodiment. For example, in the said embodiment, although the laminated | multilayer film 2 showed 3 layer structure, you may laminate | stack another layer on the 1st resin film 5. FIG. For example, a printing layer and a varnish layer are mentioned.

  When the laminated film 2 is end-sealed, as in the package 10 shown in FIG. 5, the both sides of the portion that becomes the end seal portion are folded once inward, and the thickness direction of the wet tissue It is good also as a mode heat-sealed twice. In this embodiment, a wide gusset can be formed on the side portion, and more wet tissue can be accommodated.

  Hereinafter, the contents of the present invention will be described more specifically with reference to experimental examples. In addition, this invention is not limited to the following Example.

<Confirmation experiment 1>
Polyethylene terephthalate (PET) film (thickness 12 μm) as the first resin film, aluminum foil (thickness 7 μm), and linear low-density polyethylene (LLDPE) film (Mitsui Chemicals East Cello) as the second resin film “FCD-NP” (trade name) of Co., Ltd .: 1-butene (C4) as a comonomer unit, thickness of 40 μm) was dry laminated to produce a laminated film. An opening was provided in the laminated film, and a lid made of the same laminated film was adhered to the laminated film using an acrylic resin as an adhesive. Using this laminated film, a wet tissue made of a nonwoven fabric impregnated with a non-alcohol drug is packaged by heat sealing (the shape of the end seal portion is the embodiment shown in FIG. 5) to obtain a package (test body). It was.

The following four types of durability test conditions were adopted.
(Condition 1) Temperature = −20 ° C., relative humidity is normal, period = 7 days (Condition 2) Temperature = 70 ° C., relative humidity = 60%, period = 7 days (Condition 3) Temperature = 80 ° C., relative humidity = 60%, period = 7 days (Condition 4) Cycle test = 23 ° C. (normal temperature) is maintained for 2 hours, then the temperature is lowered to −20 ° C. over 2 hours and maintained for 6 hours. Thereafter, the temperature is raised to 70 ° C. over 2 hours and maintained for 6 hours. Thereafter, the temperature is lowered to −20 ° C. over 2 hours and maintained for 6 hours. Thereafter, the temperature is raised to 70 ° C. over 2 hours and maintained for 6 hours. Then return to 23 ° C. over 2 hours.

  Two specimens were prepared for each test condition and used for the test. After the test, after 1 hour, each package was cut open with scissors, and the presence or absence of delamination in the heat seal portion was visually observed. The results are shown in Table 1.

  From these results, it was found that the linear low density polyethylene (LLDPE) film is not suitable for long-term storage of wet tissue in a high temperature environment. In any of the examples, no abnormality was observed in the external shape and adhesiveness of the lid.

  Moreover, the chemical | medical solution was collect | recovered from the package which the delamination did not arise in condition 1 and condition 2, and the skin primary irritation test using a rabbit was done. The test was conducted in accordance with “OECD Guideline for Testing of Chemicals 404 (2015)”. The drug solution was closed and applied to 3 rabbits' intact skin and wounded skin for 4 hours. As a result, at any chemical solution application site, very mild to clear erythema was observed in all cases 1 hour after removal, but all disappeared within 24 hours. The primary irritancy index (PI) determined according to “ISO 10993-10: 2010, Biological evaluation of medical devices-Part 10” was 0 for each drug solution. From these facts, it can be said that in the primary skin irritation test using rabbits, the drug solution falls within the category of “no irritation”.

<Confirmation experiment 2>
Polyethylene terephthalate (PET) film (thickness 12 μm) as the first resin film, aluminum foil (thickness 7 μm), and unstretched polypropylene (CPP) film (the Toyobo Co., Ltd. Film-CT P1128 ”(trade name), thickness 40 μm), heat-resistant linear low-density polyethylene (heat-resistant LLDPE) film (“ Rix film LIX-1 L6101 ”(trade name), thickness 50 μm from Toyobo Co., Ltd.), Alternatively, a heat-resistant unstretched polypropylene (heat-resistant CPP) film (“Pyrene Film-CTP1153” (trade name) of Toyobo Co., Ltd., thickness: 50 μm) was dry-laminated to prepare each laminated film. Each laminated film was provided with an opening, and a lid made of the same laminated film was adhered to the laminated film using an acrylic resin as an adhesive. Using each laminated film, a wet tissue (sheet size: 20 cm × 20 cm) made of a nonwoven fabric impregnated with a non-alcohol drug is folded and wrapped by heat sealing (the shape of the end seal portion is the mode shown in FIG. 1). ) And a package (test body) was obtained. The area (inside dimension) on the second resin film side excluding the heat-sealed portion of the package was 19.0 cm × 26.3 cm (= about 500 cm ² ).

  Here, the heat sealing at the center portion was performed in two stages, preheating and main heat. Moreover, about each raw material of the 2nd resin film, the package was produced in three types, the temperature of heat seal, low temperature, medium temperature, and high temperature.

In Examples 1 to 9, the number of sheets was unified to 30 sheets, and the amount of the chemical solution was unified to 180 ml. In Example 10, a small-sized package (inner dimensions were 12.0 cm × 19.0 cm (= 228 cm ² ) and sheet size was 19 cm × 11.5 cm) was used. In Examples 11 to 14, the material and the heat seal temperature used in Example 4 were adopted, and the number of sheets and the amount of the chemical solution were changed. The status of each example is shown in Tables 2 and 3. The “wet tissue weight” in Tables 2 and 3 refers to the total weight of the non-woven fabric prepared for preparing the wet tissue and the drug prepared for impregnation thereof.

The weights of the packages of Examples 1 to 14 were measured, and then stored for 7 days in a temperature environment of 80 ° C. After storage, the sample was taken out from the high temperature environment, and after 1 hour, the weight was measured. Then, the package was cut open with scissors, and the presence or absence of rupture of the package and the degree of delamination of the heat seal portion were visually observed. The results are shown in Table 4. The evaluation index for the degree of delamination is as follows.
“A”: No delamination occurred.
“B”: Slight delamination occurred.
“C”: Slight delamination occurred.
"D" ... Some delamination occurred, but not enough to open a hole leading to the outside.

  In any of the examples, the change in weight before and after the test is slight (or within the measurement error range), so that it can be said that any package remains sealed even after being exposed to a high temperature environment. It turned out that there was no trouble in storage. Further, it was found that delamination hardly occurs when a heat-resistant linear low-density polyethylene (heat-resistant LLDPE) film is used as the second resin film and the amount of the chemical solution is relatively reduced (Example 11). ~ 14). In any of the examples, no abnormality was observed in the state of sealing with the lid.

  Moreover, when the chemical | medical solution was extract | collected from the package after the test of Example 4, and the presence or absence of methanol was confirmed with the gas chromatography, methanol was not detected (detection limit is 60 ppm). Moreover, when pH of the extract | collected chemical | medical solution was measured by the glass electrode method, pH was 6.78 and it was settled in the range of pH 6-8 at the time of package preparation.

<Confirmation experiment 3>
Using the package produced in Example 13, the following three types were adopted as test conditions for the durability test.
(Condition 5) Temperature = −20 ° C., relative humidity is normal, period = 7 days (Condition 6) Temperature = 80 ° C., relative humidity = 60%, period = 7 days (Condition 7) Cycle test = 23 ° C. (normal temperature) For 2 hours, then reduce the temperature to −20 ° C. over 2 hours and maintain for 6 hours. Thereafter, the temperature is raised to 80 ° C. over 2 hours and maintained for 6 hours. Thereafter, the temperature is lowered to −20 ° C. over 2 hours and maintained for 6 hours. Thereafter, the temperature is raised to 80 ° C. over 2 hours and maintained for 6 hours. Then return to 23 ° C. over 2 hours.

  Three specimens were prepared for each test condition and used for the test. After 1 hour after the test, each package was cut open with scissors, the state of mass change before and after the test and the state of the lid were examined, and the presence or absence of delamination in the heat seal portion was visually observed. The results are shown in Table 5. Here, the index of “degree of delamination” is the same as that in <Confirmation Experiment 2>.

  In any test, the change in weight before and after the test is slight (or measurement error range), so it can be said that the sealing performance is maintained even after any of the conditions 5 to 7, which hinders long-term storage. I found that there was no. In addition, no change was observed in the shape or the pressure-sensitive adhesive of any of the lid materials, and no trouble was observed in the repeated adhesion. In addition, delamination was not observed in any of the specimens, and no abnormality was observed in the internal appearance.

  Moreover, when a chemical | medical solution was extract | collected from the package after the durability test in the conditions 5, 6 and 7, and pH was measured by the glass electrode method, pH was 7.68, 7.21, and 7.54, respectively. Yes, there was almost no change from pH 7.72 at the time of packaging production.

  Furthermore, the skin primary irritation test using rabbits was performed using the chemicals collected from the package after the durability test under conditions 6 and 7. The test was conducted in accordance with “OECD Guideline for Testing of Chemicals 404 (2015)”. The drug solution was closed and applied to 3 rabbits' intact skin and wounded skin for 4 hours. As a result, in any chemical application site, clear erythema was observed in all cases 1 hour after removal, but all disappeared within 48 hours. The primary irritancy index (PI) determined according to “ISO 10993-10: 2010, Biological evaluation of medical devices-Part 10” was 0.1 for each drug solution. From these facts, it can be said that in the primary skin irritation test using rabbits, the drug solution falls within the category of “no irritation”.

  The present invention can be used as a packaging material for wet tissue. The wet tissue package can be stored in the vehicle for a long time, for example, for in-vehicle use.

  DESCRIPTION OF SYMBOLS 1 ... Wet tissue packaging body, 2 ... Laminated film for wet tissue packaging, 2A ... Center seal part, 2B, 2B ... End seal part, 2C ... Opening part, 3 ... Wet tissue, 4 ... Cover material, 5 ... First Resin film, 6 ... aluminum foil, 7 ... second resin film, 10 ... package.

Claims (6)

A wet tissue in which a base material is impregnated with a drug;
A first resin film, an aluminum foil, and a second resin film having heat sealing properties are laminated in this order, and the second resin film is an unstretched polypropylene film, a heat-resistant unstretched polypropylene film, Or a laminated film for wet tissue packaging which is a heat-resistant linear low-density polyethylene film ,
The wet tissue packaging laminated film surrounds the wet tissue with the second resin film side facing inward, and the second resin film side surfaces face each other and are heat-sealed. The wet tissue is sealed by the laminated film for wet tissue packaging ,
The tensile elastic modulus (measured according to JIS K7127) of the unstretched polypropylene film is 500 to 650 MPa in both the longitudinal direction and the transverse direction.
The tensile elastic modulus (measured according to JIS K7127) of the heat-resistant unstretched polypropylene film is 250 to 450 MPa in both the longitudinal direction and the transverse direction.
The heat shrinkage (90 ° C., 30 minutes, measured in accordance with JIS K6782) of the linear low-density polyethylene film is 1.0% or less in both the vertical direction and the horizontal direction.
The heat shrinkage rate of the heat-resistant unstretched polypropylene film (120 ° C., 30 minutes, measured according to JIS K6782) is 2.0% or less in both the vertical direction and the horizontal direction.
A wet tissue package for in-vehicle use . The first resin film is a polyethylene terephthalate film,
The wet tissue package according to claim 1, wherein the first resin film, the aluminum foil, and the second resin film are laminated by dry lamination. The ratio of the volume value (unit: ml) of the drug to the area value (unit: cm ² ) on the second resin film side excluding the heat-sealed portion is 0.10 to 0.50. The wet tissue package according to claim 1 or 2 . The ratio of the weight value (unit: g) of the wet tissue to the area value (unit: cm ² ) on the second resin film side excluding the heat-sealed portion is 0.10 to 0.75. The wet tissue package of Claim 1 or 2 . The laminated film for wet tissue packaging has an opening for taking out the wet tissue,
The wet tissue package according to any one of claims 1 to 4 , further comprising a lid that covers the opening so as to be openable and closable. The wet tissue package according to any one of claims 1 to 5 , wherein the drug is a non-alcohol drug.

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