JP6426599B2 - 乳汁分泌の管理用のペプチド - Google Patents

乳汁分泌の管理用のペプチド Download PDF

Info

Publication number
JP6426599B2
JP6426599B2 JP2015501047A JP2015501047A JP6426599B2 JP 6426599 B2 JP6426599 B2 JP 6426599B2 JP 2015501047 A JP2015501047 A JP 2015501047A JP 2015501047 A JP2015501047 A JP 2015501047A JP 6426599 B2 JP6426599 B2 JP 6426599B2
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
amino acid
seq
peptide
ser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2015501047A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015516377A (ja
Inventor
イスコヴィッチ,ホセ,マリオ
イスコヴィッチ,ハビエル
Original Assignee
ミレウティス リミテッド.
ミレウティス リミテッド.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ミレウティス リミテッド., ミレウティス リミテッド. filed Critical ミレウティス リミテッド.
Publication of JP2015516377A publication Critical patent/JP2015516377A/ja
Application granted granted Critical
Publication of JP6426599B2 publication Critical patent/JP6426599B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4732Casein
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1019Tetrapeptides with the first amino acid being basic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2015501047A 2012-03-19 2013-03-08 乳汁分泌の管理用のペプチド Active JP6426599B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261612410P 2012-03-19 2012-03-19
US61/612,410 2012-03-19
PCT/IL2013/050214 WO2013140388A1 (en) 2012-03-19 2013-03-08 Peptides for management of lactation

Publications (2)

Publication Number Publication Date
JP2015516377A JP2015516377A (ja) 2015-06-11
JP6426599B2 true JP6426599B2 (ja) 2018-11-21

Family

ID=49221927

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015501047A Active JP6426599B2 (ja) 2012-03-19 2013-03-08 乳汁分泌の管理用のペプチド

Country Status (11)

Country Link
US (1) US9487557B2 (enExample)
EP (1) EP2828281B1 (enExample)
JP (1) JP6426599B2 (enExample)
CN (1) CN104321336B (enExample)
AU (1) AU2013236975B2 (enExample)
BR (1) BR112014023087A8 (enExample)
CA (1) CA2867557C (enExample)
ES (1) ES2759980T3 (enExample)
IL (1) IL234574B (enExample)
IN (1) IN2014DN08610A (enExample)
WO (1) WO2013140388A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102022118B1 (ko) * 2019-01-07 2019-09-18 주식회사 아스트로젠 중추신경계 질환의 예방 또는 치료용 세린 유도체 화합물
CN111632128B (zh) * 2019-02-14 2022-07-05 三凡生技研发股份有限公司 短链胜肽组合物在预防或治疗干眼症的应用
AU2020394498A1 (en) 2019-11-28 2022-06-09 Boehringer Ingelheim Vetmedica Gmbh Use of SGLT-2 inhibitors in the drying-off of non-human mammals
BR112023022624A2 (pt) * 2021-04-28 2024-01-16 Mileutis Ltd Composições e métodos para modular distúrbios e condições mamárias

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391849B1 (en) 1999-11-19 2002-05-21 Agricultural Research Organization, The Volcani Center Method and pharmaceutical composition for disrupting lactation in a mammary gland and for treating and preventing mastitis
CN1496368A (zh) 2001-03-09 2004-05-12 明治制果株式会社 免疫增强剂
CN101247721B (zh) * 2005-05-02 2016-08-03 米勒尤迪斯公司 包括酪蛋白衍生肽的药物组合物及其使用方法
ES2400511T3 (es) * 2005-05-02 2013-04-10 Mileutis Ltd. Composiciones farmacéuticas que comprenden péptidos derivados de la caseina y métodos para el uso de las mismas
WO2009023270A2 (en) * 2007-08-15 2009-02-19 Amunix, Inc. Compositions and methods for modifying properties of biologically active polypeptides

Also Published As

Publication number Publication date
ES2759980T3 (es) 2020-05-12
CA2867557C (en) 2020-03-10
US20150093400A1 (en) 2015-04-02
IN2014DN08610A (enExample) 2015-05-22
EP2828281A4 (en) 2015-11-11
BR112014023087A2 (pt) 2017-06-20
EP2828281A1 (en) 2015-01-28
BR112014023087A8 (pt) 2018-01-16
CN104321336B (zh) 2021-08-06
US9487557B2 (en) 2016-11-08
AU2013236975A1 (en) 2014-10-23
IL234574B (en) 2020-09-30
JP2015516377A (ja) 2015-06-11
CN104321336A (zh) 2015-01-28
EP2828281B1 (en) 2019-09-18
WO2013140388A1 (en) 2013-09-26
AU2013236975B2 (en) 2017-10-19
CA2867557A1 (en) 2013-09-26

Similar Documents

Publication Publication Date Title
US8338363B2 (en) Pharmaceutical compositions comprising casein derived peptides and methods of use thereof
JP6426599B2 (ja) 乳汁分泌の管理用のペプチド
US20090305947A1 (en) Livestock management for improved reproductive efficiency
US20240207352A1 (en) Compositions and methods for modulating mammary disorders and conditions
CN101247721B (zh) 包括酪蛋白衍生肽的药物组合物及其使用方法
AU2012200889B2 (en) Pharmaceutical compositions comprising casein derived peptides and methods of use thereof
CN106117315B (zh) 五肽在治疗金葡菌奶牛乳房炎中的医用用途
JP2025537820A (ja) 乳房の障害および状態を調節するための組成物および方法
HK1120368A (en) Pharmaceutical compositions comprising casein derived peptides and methods of use thereof
TW202440610A (zh) 具傷口癒合功效之鱸魚胜肽及其組成物
IL222487A (en) Casein-derived peptides and methods for using them to increase milk yield
IL222486A (en) Casein-derived peptides and methods for using them to enhance milk cleanliness
IL187120A (en) Casein-derived peptides and methods for their use in the herd's interface with milk
JPH07309774A (ja) 抗真菌剤
CN106188233A (zh) 一种治疗金葡菌奶牛乳房炎的多肽及制备工艺
MXPA00011511A (es) Inducción de proteinas y peptidos antibioticos por proteina lait/scd14

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20160307

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20170228

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20170525

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20170727

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170817

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20171226

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20180320

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180525

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20180925

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20181025

R150 Certificate of patent or registration of utility model

Ref document number: 6426599

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250