JP6417568B2 - 抗インフルエンザ組成物及び方法 - Google Patents

抗インフルエンザ組成物及び方法 Download PDF

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JP6417568B2
JP6417568B2 JP2016514060A JP2016514060A JP6417568B2 JP 6417568 B2 JP6417568 B2 JP 6417568B2 JP 2016514060 A JP2016514060 A JP 2016514060A JP 2016514060 A JP2016514060 A JP 2016514060A JP 6417568 B2 JP6417568 B2 JP 6417568B2
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compound
alkylene
pharmaceutically acceptable
independently
lower alkyl
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Japanese (ja)
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JP2016518451A5 (enExample
JP2016518451A (ja
Inventor
ピー シェリダン，ウィリアム
ピー シェリダン，ウィリアム
バンティア，シャンタ
エル コティアン，プラヴィン
エル コティアン，プラヴィン
エス バブ，ヤーラガッダ
エス バブ，ヤーラガッダ
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Biocryst Pharmaceuticals Inc
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Biocryst Pharmaceuticals Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2016514060A 2013-05-14 2014-05-14 抗インフルエンザ組成物及び方法 Active JP6417568B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361823133P 2013-05-14 2013-05-14
US201361823135P 2013-05-14 2013-05-14
US61/823,133 2013-05-14
US61/823,135 2013-05-14
PCT/US2014/038000 WO2014186465A1 (en) 2013-05-14 2014-05-14 Anti-influenza compositions and methods

Publications (3)

Publication Number Publication Date
JP2016518451A JP2016518451A (ja) 2016-06-23
JP2016518451A5 JP2016518451A5 (enExample) 2017-06-29
JP6417568B2 true JP6417568B2 (ja) 2018-11-07

Family

ID=51898845

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016514060A Active JP6417568B2 (ja) 2013-05-14 2014-05-14 抗インフルエンザ組成物及び方法

Country Status (6)

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US (2) US9499554B2 (enExample)
EP (1) EP2996685B1 (enExample)
JP (1) JP6417568B2 (enExample)
AU (1) AU2014265483B2 (enExample)
CA (1) CA2911424C (enExample)
WO (1) WO2014186465A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112250601B (zh) * 2020-09-08 2022-09-27 天津应天成科技有限公司 安全无毒去除帕拉米韦三水合物中间体m9中镍离子杂质的方法
CN118119624A (zh) 2021-08-20 2024-05-31 盐野义制药株式会社 具有病毒增殖抑制作用的核苷衍生物及其前药

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6420549B1 (en) 1995-06-06 2002-07-16 Isis Pharmaceuticals, Inc. Oligonucleotide analogs having modified dimers
AU2200199A (en) * 1997-12-17 1999-07-19 Biocryst Pharmaceuticals, Inc. Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors
CN101610772B (zh) * 2007-02-16 2013-01-16 富山化学工业株式会社 包含吡嗪衍生物的药物组合物和使用吡嗪衍生物的联合用药的方法
EP2192923A2 (en) * 2007-08-27 2010-06-09 Massachusetts Institute of Technology Bi-functional polymer-attached inhibitors of influenza virus
EA201101564A1 (ru) * 2009-05-15 2012-07-30 Редкс Фарма Лимитед Редокс производные лекарственных средств
US20130023585A1 (en) 2010-04-02 2013-01-24 Tsrl, Inc. Neuraminidase Inhibitors
RS56870B1 (sr) 2010-10-15 2018-04-30 Biocryst Pharm Inc Pirolopirimidinski derivati za primenu u lečenju virusnih infekcija
US9309363B2 (en) * 2012-03-30 2016-04-12 Rohm And Haas Company Product and method for making uniform spherical, acrylic polymeric beads

Also Published As

Publication number Publication date
EP2996685A4 (en) 2016-12-07
HK1222560A1 (en) 2017-07-07
WO2014186465A1 (en) 2014-11-20
US20170137429A1 (en) 2017-05-18
AU2014265483A1 (en) 2015-12-17
US9499554B2 (en) 2016-11-22
EP2996685A1 (en) 2016-03-23
US20160096842A1 (en) 2016-04-07
CA2911424C (en) 2021-11-30
JP2016518451A (ja) 2016-06-23
CA2911424A1 (en) 2014-11-20
AU2014265483B2 (en) 2018-08-02
EP2996685B1 (en) 2019-03-27

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