CA2911424C - Anti-influenza imino-ribose pyrrolopyrimidine derivatives - Google Patents
Anti-influenza imino-ribose pyrrolopyrimidine derivatives Download PDFInfo
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- CA2911424C CA2911424C CA2911424A CA2911424A CA2911424C CA 2911424 C CA2911424 C CA 2911424C CA 2911424 A CA2911424 A CA 2911424A CA 2911424 A CA2911424 A CA 2911424A CA 2911424 C CA2911424 C CA 2911424C
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361823133P | 2013-05-14 | 2013-05-14 | |
| US201361823135P | 2013-05-14 | 2013-05-14 | |
| US61/823,133 | 2013-05-14 | ||
| US61/823,135 | 2013-05-14 | ||
| PCT/US2014/038000 WO2014186465A1 (en) | 2013-05-14 | 2014-05-14 | Anti-influenza compositions and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2911424A1 CA2911424A1 (en) | 2014-11-20 |
| CA2911424C true CA2911424C (en) | 2021-11-30 |
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|---|---|---|---|
| CA2911424A Active CA2911424C (en) | 2013-05-14 | 2014-05-14 | Anti-influenza imino-ribose pyrrolopyrimidine derivatives |
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| Country | Link |
|---|---|
| US (2) | US9499554B2 (enExample) |
| EP (1) | EP2996685B1 (enExample) |
| JP (1) | JP6417568B2 (enExample) |
| AU (1) | AU2014265483B2 (enExample) |
| CA (1) | CA2911424C (enExample) |
| WO (1) | WO2014186465A1 (enExample) |
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| CN112250601B (zh) * | 2020-09-08 | 2022-09-27 | 天津应天成科技有限公司 | 安全无毒去除帕拉米韦三水合物中间体m9中镍离子杂质的方法 |
| CN118119624A (zh) | 2021-08-20 | 2024-05-31 | 盐野义制药株式会社 | 具有病毒增殖抑制作用的核苷衍生物及其前药 |
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| US6420549B1 (en) | 1995-06-06 | 2002-07-16 | Isis Pharmaceuticals, Inc. | Oligonucleotide analogs having modified dimers |
| AU2200199A (en) * | 1997-12-17 | 1999-07-19 | Biocryst Pharmaceuticals, Inc. | Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors |
| CN101610772B (zh) * | 2007-02-16 | 2013-01-16 | 富山化学工业株式会社 | 包含吡嗪衍生物的药物组合物和使用吡嗪衍生物的联合用药的方法 |
| EP2192923A2 (en) * | 2007-08-27 | 2010-06-09 | Massachusetts Institute of Technology | Bi-functional polymer-attached inhibitors of influenza virus |
| EA201101564A1 (ru) * | 2009-05-15 | 2012-07-30 | Редкс Фарма Лимитед | Редокс производные лекарственных средств |
| US20130023585A1 (en) | 2010-04-02 | 2013-01-24 | Tsrl, Inc. | Neuraminidase Inhibitors |
| RS56870B1 (sr) | 2010-10-15 | 2018-04-30 | Biocryst Pharm Inc | Pirolopirimidinski derivati za primenu u lečenju virusnih infekcija |
| US9309363B2 (en) * | 2012-03-30 | 2016-04-12 | Rohm And Haas Company | Product and method for making uniform spherical, acrylic polymeric beads |
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2014
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- 2014-05-14 EP EP14798158.3A patent/EP2996685B1/en active Active
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2016
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| Publication number | Publication date |
|---|---|
| EP2996685A4 (en) | 2016-12-07 |
| HK1222560A1 (en) | 2017-07-07 |
| WO2014186465A1 (en) | 2014-11-20 |
| JP6417568B2 (ja) | 2018-11-07 |
| US20170137429A1 (en) | 2017-05-18 |
| AU2014265483A1 (en) | 2015-12-17 |
| US9499554B2 (en) | 2016-11-22 |
| EP2996685A1 (en) | 2016-03-23 |
| US20160096842A1 (en) | 2016-04-07 |
| JP2016518451A (ja) | 2016-06-23 |
| CA2911424A1 (en) | 2014-11-20 |
| AU2014265483B2 (en) | 2018-08-02 |
| EP2996685B1 (en) | 2019-03-27 |
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