JP6378777B2 - 患者固有の血管幾何形状及び境界条件の変化をモデリングするためのシステム及びその作動方法 - Google Patents

患者固有の血管幾何形状及び境界条件の変化をモデリングするためのシステム及びその作動方法 Download PDF

Info

Publication number
JP6378777B2
JP6378777B2 JP2016558352A JP2016558352A JP6378777B2 JP 6378777 B2 JP6378777 B2 JP 6378777B2 JP 2016558352 A JP2016558352 A JP 2016558352A JP 2016558352 A JP2016558352 A JP 2016558352A JP 6378777 B2 JP6378777 B2 JP 6378777B2
Authority
JP
Japan
Prior art keywords
patient
model
physiological
anatomical
state
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2016558352A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017510350A5 (enExample
JP2017510350A (ja
Inventor
チャールズ エー． テイラー，
チャールズ エー． テイラー，
ヒュン ジン キム，
ヒュン ジン キム，
セスラマン サンカラン，
セスラマン サンカラン，
マイケル シャープ，
マイケル シャープ，
デイビッド エバール，
デイビッド エバール，
ギルウー チョイ，
ギルウー チョイ，
レオ ジェイ． グラディー，
レオ ジェイ． グラディー，
Original Assignee
ハートフロー， インコーポレイテッド
ハートフロー， インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ハートフロー， インコーポレイテッド, ハートフロー， インコーポレイテッド filed Critical ハートフロー， インコーポレイテッド
Publication of JP2017510350A publication Critical patent/JP2017510350A/ja
Publication of JP2017510350A5 publication Critical patent/JP2017510350A5/ja
Application granted granted Critical
Publication of JP6378777B2 publication Critical patent/JP6378777B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F30/00—Computer-aided design [CAD]
    • G06F30/20—Design optimisation, verification or simulation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment

Landscapes

  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Primary Health Care (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Geometry (AREA)
  • Evolutionary Computation (AREA)
  • Computer Hardware Design (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Instructional Devices (AREA)
JP2016558352A 2014-03-24 2015-03-23 患者固有の血管幾何形状及び境界条件の変化をモデリングするためのシステム及びその作動方法 Active JP6378777B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461969573P 2014-03-24 2014-03-24
US61/969,573 2014-03-24
US14/317,726 US9390232B2 (en) 2014-03-24 2014-06-27 Systems and methods for modeling changes in patient-specific blood vessel geometry and boundary conditions
US14/317,726 2014-06-27
PCT/US2015/022062 WO2015148401A1 (en) 2014-03-24 2015-03-23 Systems and methods for modeling changes in patent-specific blood vessel geometry and boundary conditions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018141442A Division JP6665240B2 (ja) 2014-03-24 2018-07-27 患者固有の血管幾何形状及び境界条件の変化をモデリングするためのシステム及びその作動方法

Publications (3)

Publication Number Publication Date
JP2017510350A JP2017510350A (ja) 2017-04-13
JP2017510350A5 JP2017510350A5 (enExample) 2017-06-01
JP6378777B2 true JP6378777B2 (ja) 2018-08-22

Family

ID=54142391

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2016558352A Active JP6378777B2 (ja) 2014-03-24 2015-03-23 患者固有の血管幾何形状及び境界条件の変化をモデリングするためのシステム及びその作動方法
JP2018141442A Active JP6665240B2 (ja) 2014-03-24 2018-07-27 患者固有の血管幾何形状及び境界条件の変化をモデリングするためのシステム及びその作動方法
JP2020026113A Pending JP2020157047A (ja) 2014-03-24 2020-02-19 患者固有の血管幾何形状及び境界条件の変化をモデリングするためのシステム及びその作動方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2018141442A Active JP6665240B2 (ja) 2014-03-24 2018-07-27 患者固有の血管幾何形状及び境界条件の変化をモデリングするためのシステム及びその作動方法
JP2020026113A Pending JP2020157047A (ja) 2014-03-24 2020-02-19 患者固有の血管幾何形状及び境界条件の変化をモデリングするためのシステム及びその作動方法

Country Status (4)

Country Link
US (6) US9390232B2 (enExample)
EP (1) EP3123373A1 (enExample)
JP (3) JP6378777B2 (enExample)
WO (1) WO2015148401A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017525497A (ja) * 2014-08-29 2017-09-07 ハートフロー， インコーポレイテッド 血流特性及び病理を心筋血液供給のモデリングを介して決定するためのシステム及び方法
JP2019005592A (ja) * 2014-03-24 2019-01-17 ハートフロー， インコーポレイテッド 患者固有の血管幾何形状及び境界条件の変化をモデリングするためのシステム及びその作動方法

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE051987T2 (hu) 2013-03-15 2021-04-28 Annmarie Hipsley Rendszerek kötõszövet biomechanikai tulajdonságainak befolyásolására
EP2994904A4 (en) 2013-05-10 2017-01-18 Stenomics, Inc. Modeling and simulation system for optimizing prosthetic heart valve treatment
US9092743B2 (en) 2013-10-23 2015-07-28 Stenomics, Inc. Machine learning system for assessing heart valves and surrounding cardiovascular tracts
US9292659B1 (en) 2014-10-29 2016-03-22 Heartflow, Inc. Systems and methods for vessel reactivity to guide diagnosis or treatment of cardiovascular disease
TWI547261B (zh) * 2015-01-29 2016-09-01 原相科技股份有限公司 陣列式生理偵測系統及其運作方法
US11020013B2 (en) 2015-01-29 2021-06-01 Pixart Imaging Inc. Array physiological detection system and device
US11311203B2 (en) 2015-01-29 2022-04-26 Pixart Imaging Inc. Microcirculation detection system
EP3062248A1 (en) * 2015-02-27 2016-08-31 Pie Medical Imaging BV Method and apparatus for quantitative flow analysis
US11113812B2 (en) 2015-08-14 2021-09-07 Elucid Bioimaging Inc. Quantitative imaging for detecting vulnerable plaque
US11676359B2 (en) 2015-08-14 2023-06-13 Elucid Bioimaging Inc. Non-invasive quantitative imaging biomarkers of atherosclerotic plaque biology
US10176408B2 (en) 2015-08-14 2019-01-08 Elucid Bioimaging Inc. Systems and methods for analyzing pathologies utilizing quantitative imaging
US12026868B2 (en) 2015-08-14 2024-07-02 Elucid Bioimaging Inc. Quantitative imaging for detecting histopathologically defined plaque erosion non-invasively
US11087459B2 (en) 2015-08-14 2021-08-10 Elucid Bioimaging Inc. Quantitative imaging for fractional flow reserve (FFR)
US12008751B2 (en) 2015-08-14 2024-06-11 Elucid Bioimaging Inc. Quantitative imaging for detecting histopathologically defined plaque fissure non-invasively
US11071501B2 (en) 2015-08-14 2021-07-27 Elucid Bioiwaging Inc. Quantitative imaging for determining time to adverse event (TTE)
US11094058B2 (en) 2015-08-14 2021-08-17 Elucid Bioimaging Inc. Systems and method for computer-aided phenotyping (CAP) using radiologic images
WO2017147500A1 (en) 2016-02-26 2017-08-31 Heartflow, Inc. Systems and methods for identifying and modeling unresolved vessels in image-based patient-specific hemodynamic models
US9824492B2 (en) 2016-03-24 2017-11-21 Vital Images, Inc. Hollow object model visualization in medical images
JP6669361B2 (ja) * 2016-04-12 2020-03-18 Ｎｅｃソリューションイノベータ株式会社 血流解析システム、解析依頼受付システム、血流解析方法及びプログラム
WO2018005888A1 (en) * 2016-06-29 2018-01-04 Ace Vision Group, Inc. 3-dimensional model creation using whole eye finite element modeling of human ocular structures
US11039804B2 (en) * 2016-09-16 2021-06-22 Koninklijke Philips N.V. Apparatus and method for determining a fractional flow reserve
WO2018057507A1 (en) 2016-09-20 2018-03-29 Heartflow, Inc. Systems and methods for monitoring and updating blood flow calculations with user-specific anatomic and physiologic sensor data
EP3375364B1 (en) * 2017-01-23 2024-08-28 Shanghai United Imaging Healthcare Co., Ltd. System and method for analyzing blood flow state
JP7313284B2 (ja) 2017-04-06 2023-07-24 コーニンクレッカ フィリップス エヌ ヴェ 冠血流予備量比シミュレーションパラメータのカスタマイズ、キャリブレーション、及び／又はトレーニング
WO2019071249A1 (en) 2017-10-06 2019-04-11 Emory University METHODS AND SYSTEMS FOR DETERMINING HEMODYNAMIC INFORMATION FOR ONE OR MORE ARTERIAL SEGMENTS
US11871995B2 (en) 2017-12-18 2024-01-16 Hemolens Diagnostics Sp. Z O.O. Patient-specific modeling of hemodynamic parameters in coronary arteries
JP7250435B2 (ja) * 2018-05-21 2023-04-03 キヤノンメディカルシステムズ株式会社 デバイス施術支援装置、プログラム、方法及びシステム
EP3628652A1 (en) * 2018-09-28 2020-04-01 Eberhard Karls Universität Tübingen Method for the stereoisomerization of chiral compounds
JP7616806B2 (ja) * 2019-05-17 2025-01-17 ハートフロー， インコーポレイテッド 応答曲面および減次モデル化を使用した血流の推定のためのシステムおよび方法
KR20210121062A (ko) 2019-08-05 2021-10-07 엘루시드 바이오이미징 아이엔씨. 형태학적 및 혈관주위 질환 표지자의 조합 평가
CA3164482A1 (en) * 2020-01-16 2021-07-22 Alexander S. LIBERSON Noninvasive diagnostics of proximal heart health biomarkers
DE102020200750A1 (de) * 2020-01-22 2021-07-22 Siemens Healthcare Gmbh Bereitstellen eines Blutflussparametersatzes einer Gefäßmalformation
CN111369519B (zh) * 2020-03-02 2021-09-17 博动医学影像科技（上海）有限公司 冠状动脉的血流速度的计算方法、装置及电子设备
CN112971979B (zh) * 2021-02-03 2022-08-16 上海友脉科技有限责任公司 仿真系统、仿真方法及装置
US20230149088A1 (en) * 2021-11-17 2023-05-18 Brown University Large vessel occlusion detection and treatment prediction
CN114587587B (zh) * 2022-04-02 2022-10-14 哈尔滨理工大学 一种异物网篮钳取异物的方法
US20230355106A1 (en) * 2022-05-06 2023-11-09 Boston Scientific Scimed, Inc. Predicting Vessel Compliance Responsive to Multiple Potential Treatments

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1746558B1 (en) * 2005-07-20 2013-07-17 MedTAG Ltd. A system for simulating a manual interventional operation by a user in a medical procedure
WO2009081304A2 (en) * 2007-12-18 2009-07-02 Koninklijke Philips Electronics, N.V. Integration of physiological models in medical decision support systems
US8200466B2 (en) 2008-07-21 2012-06-12 The Board Of Trustees Of The Leland Stanford Junior University Method for tuning patient-specific cardiovascular simulations
US8682626B2 (en) * 2010-07-21 2014-03-25 Siemens Aktiengesellschaft Method and system for comprehensive patient-specific modeling of the heart
US8157742B2 (en) 2010-08-12 2012-04-17 Heartflow, Inc. Method and system for patient-specific modeling of blood flow
US8315812B2 (en) 2010-08-12 2012-11-20 Heartflow, Inc. Method and system for patient-specific modeling of blood flow
US20120084064A1 (en) 2010-09-29 2012-04-05 Nutech Ventures, Inc. Model-based systems and methods for analyzing and predicting outcomes of vascular interventions and reconstructions
US8920322B2 (en) * 2011-03-09 2014-12-30 Siemens Aktiengesellschaft Valve treatment simulation from medical diagnostic imaging data
US9724164B2 (en) * 2011-08-26 2017-08-08 EBM Corporation Blood-vessel bloodstream simulation system, method therefor, and computer software program
US10162932B2 (en) 2011-11-10 2018-12-25 Siemens Healthcare Gmbh Method and system for multi-scale anatomical and functional modeling of coronary circulation
US10373700B2 (en) * 2012-03-13 2019-08-06 Siemens Healthcare Gmbh Non-invasive functional assessment of coronary artery stenosis including simulation of hyperemia by changing resting microvascular resistance
WO2013138428A1 (en) * 2012-03-15 2013-09-19 Siemens Aktiengesellschaft A framework for personalization of coronary flow computations during rest and hyperemia
JP5946127B2 (ja) * 2012-05-11 2016-07-05 富士通株式会社 シミュレーション方法、シミュレーション装置、およびシミュレーションプログラム
US9247918B2 (en) * 2012-07-09 2016-02-02 Siemens Aktiengesellschaft Computation of hemodynamic quantities from angiographic data
US10433740B2 (en) * 2012-09-12 2019-10-08 Heartflow, Inc. Systems and methods for estimating ischemia and blood flow characteristics from vessel geometry and physiology
US10398386B2 (en) * 2012-09-12 2019-09-03 Heartflow, Inc. Systems and methods for estimating blood flow characteristics from vessel geometry and physiology
US9320487B2 (en) * 2012-09-25 2016-04-26 The Johns Hopkins University Method for estimating flow rates, pressure gradients, coronary flow reserve, and fractional flow reserve from patient specific computed tomography angiogram-based contrast distribution data
US9858387B2 (en) * 2013-01-15 2018-01-02 CathWorks, LTD. Vascular flow assessment
US20140288440A1 (en) * 2013-03-22 2014-09-25 Children's Medical Center Corporation Systems and methods for quantitative capnogram analysis
US9629563B2 (en) * 2013-09-04 2017-04-25 Siemens Healthcare Gmbh Method and system for functional assessment of renal artery stenosis from medical images
US9700219B2 (en) * 2013-10-17 2017-07-11 Siemens Healthcare Gmbh Method and system for machine learning based assessment of fractional flow reserve
US9390232B2 (en) * 2014-03-24 2016-07-12 Heartflow, Inc. Systems and methods for modeling changes in patient-specific blood vessel geometry and boundary conditions
US9292659B1 (en) * 2014-10-29 2016-03-22 Heartflow, Inc. Systems and methods for vessel reactivity to guide diagnosis or treatment of cardiovascular disease
WO2017187269A1 (en) * 2016-04-29 2017-11-02 Siemens Healthcare Gmbh Enhanced personalized evaluation of coronary artery disease using an integration of multiple medical imaging techniques
US11576637B2 (en) * 2017-04-06 2023-02-14 Koninklijke Philips N.V. Standardized coronary artery disease metric
EP3884848A1 (en) * 2020-03-23 2021-09-29 Kardiolytics Inc. A system and a method for determining a significance of a stenosis

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019005592A (ja) * 2014-03-24 2019-01-17 ハートフロー， インコーポレイテッド 患者固有の血管幾何形状及び境界条件の変化をモデリングするためのシステム及びその作動方法
JP2017525497A (ja) * 2014-08-29 2017-09-07 ハートフロー， インコーポレイテッド 血流特性及び病理を心筋血液供給のモデリングを介して決定するためのシステム及び方法
JP2020044357A (ja) * 2014-08-29 2020-03-26 ハートフロー， インコーポレイテッド 血流特性及び病理を心筋血液供給のモデリングを介して決定するためのシステム及び方法
JP7039544B2 (ja) 2014-08-29 2022-03-22 ハートフロー， インコーポレイテッド 血流特性及び病理を心筋血液供給のモデリングを介して決定するためのシステム及び方法
US12178557B2 (en) 2014-08-29 2024-12-31 Heartflow, Inc. Systems and methods for determination of blood flow characteristics and pathologies through modeling of myocardial blood supply

Also Published As

Publication number Publication date
WO2015148401A8 (en) 2016-12-01
US9202010B2 (en) 2015-12-01
JP2019005592A (ja) 2019-01-17
US20150269352A1 (en) 2015-09-24
US20150269349A1 (en) 2015-09-24
JP2020157047A (ja) 2020-10-01
WO2015148401A1 (en) 2015-10-01
JP2017510350A (ja) 2017-04-13
US20150269351A1 (en) 2015-09-24
EP3123373A1 (en) 2017-02-01
JP6665240B2 (ja) 2020-03-13
US20170004280A1 (en) 2017-01-05
US20160283688A1 (en) 2016-09-29
US9390232B2 (en) 2016-07-12
US20150269350A1 (en) 2015-09-24
US10354759B2 (en) 2019-07-16

Similar Documents

Publication Publication Date Title
JP6378777B2 (ja) 患者固有の血管幾何形状及び境界条件の変化をモデリングするためのシステム及びその作動方法
JP7416617B2 (ja) 動脈の供給能力と終末器官の必要量とを比較することにより心血管疾患の診断及び評価をするためのシステム及び方法
US11229486B2 (en) Systems and methods for risk assessment and treatment planning of arteriovenous malformation
JP6905574B2 (ja) 流量比を用いて血流の特徴を決定するシステム及び方法
JP6522149B2 (ja) 生理的特性、解剖学的特性、及び患者特性から灌流障害を予測するためのシステム及び方法
KR102269495B1 (ko) 환자-특정 기하학적 모델들을 변경함으로써 치료들을 결정하기 위한 방법 및 시스템
CN110074756B (zh) 用于根据患者特定的解剖图像数据预测冠状动脉斑块易损性的系统和方法
CN106650267B (zh) 计算血流储备分数的系统和设置边界条件的方法
CN105555195A (zh) 用于从患者特定的解剖数据识别个性化的血管植入物的系统和方法
Reymond et al. Generic and patient-specific models of the arterial tree
Fossan Physics-based and data-driven reduced order models: applications to coronary artery disease diagnostics
Chabiniok et al. Translational cardiovascular modeling: tetralogy of fallot and modeling of diseases
Siogkas et al. Computational assessment of the fractional flow reserve from intravascular ultrasound and coronary angiography data: A pilot study
Chabiniok et al. Translational Cardiovascular Modeling: Tetralogy of Fallot and Modeling of
Bredbenner et al. Analysis of a probabilistic shape-based femur model
Soudah et al. A Reduced Order Model based on Coupled 1D/3D Finite Element Simulations for an Effi
Papafaklis et al. Computational assessment of the fractional flow reserve from intravascular ultrasound and coronary angiography data: A pilot...
Santhanam et al. A Framework for Modeling and Visualizing Cardiovascular Deformation Under Normal and Altered Circulatory Conditions
Min Constructing a More Realistic Numerical Model of Idealized and Patient Specific Coronary Artery Based on Two-Way FSI and CFD Simulation

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170322

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20170322

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20180117

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20180129

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180329

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20180703

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20180727

R150 Certificate of patent or registration of utility model

Ref document number: 6378777

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250