JP6348722B2 - Chemical injection device and control method thereof - Google Patents

Description

  The present invention relates to a chemical solution injection device that injects at least a contrast medium as a chemical solution into a patient, and in particular, a chemical solution injection device capable of injecting a predetermined amount of a chemical solution toward a patient within a predetermined injection time set in advance and the same It relates to a control method.

  Currently, CT (Computed Tomography) scanner, MRI (Magnetic Resonance Imaging) apparatus, PET (Positron Emission Tomography) apparatus, ultrasound diagnostic apparatus, angiography (angiography) imaging apparatus, etc. are known as medical image diagnostic apparatuses. ing. When using such an imaging apparatus, a patient may be injected with a contrast medium, physiological saline, or the like (hereinafter also simply referred to as “medical solution”).

  By the way, the following can be said about angiography. In other words, recent angiography technology using a chemical injection device is not only the development of a percutaneous catheter method, but the development of X-ray equipment, catheters, contrast agents, etc. Has evolved into (IVR). Considering each procedure, it can be divided into local arterial infusion, vascular embolization, vascular dilation and opening using a catheter. Subjects include tumors, bleeding, vascular lesions and the like. For tumors, there are intra-arterial injection of anticancer agents and transcatheter arterial embolization (TAE). For bleeding, there are continuous arterial infusion of vasoconstrictors and arterial embolization, and for vascular lesions, there are thrombolysis and percutaneous transvascular angioplasty (PTA).

  Percutaneous Transluminal Coronary Angioplasty (PTCA), which has been rapidly developed among percutaneous angioplasties currently being actively performed, is a balloon catheter and atherectomy. It can be broadly divided into (coronary atherectomy) and stent implantation. From the background of such angiographic evolution, various blood vessels directly connected to organs and lesions in the head, chest (including the heart), abdomen, and lower limbs are selectively or repeatedly imaged the same blood vessels (complexity). In order to confirm the proper blood vessel running, change the imaging angle to know the anteroposterior relationship of the blood vessels, finely adjust the injection conditions so that the catheter can not be removed, and confirm it after treatment). Is required.

  For example, Patent Document 1 discloses an example of a chemical liquid injection device for angiography. This chemical injection device is used in the following angiography methods: That is, in the catheter method, a catheter is introduced percutaneously into a blood vessel (artery) by a guide wire without incising the skin. Then, after the distal end of the catheter is positioned in the vicinity of the start portion of the target blood vessel, the drug solution injection device is operated to inject a contrast medium using a predetermined injection protocol, and continuous imaging is performed using the imaging device. Thereby, the contrasted blood vessel is displayed on a predetermined display, and the doctor performs diagnosis and treatment while viewing the image.

  The angiographic injection head has the following characteristics that are different from those of the CT examination and MR examination injection heads. In other words, angiography is characterized in that the injection pressure is very high because the drug solution is injected through a thin catheter introduced into the blood vessel.

WO2006 / 068171

  By the way, when contrast medium injection is performed, injection conditions are set in advance through, for example, a console. There are various injection condition setting methods. For example, by inputting two numerical values of “injection rate (ml / sec)” and “injection amount (ml)” in one phase, Things are known that determine the phase injection pattern.

  The injection pattern set based on “injection rate (ml / sec)” and “injection amount (ml)” is, for example, expressed as a graph of the time axis on the horizontal axis and the injection speed on the vertical axis. (It will be described later with reference to FIG. 12A). The area of the region surrounded by the rectangle is the total amount of contrast medium injected.

  However, when the contrast medium is actually injected into the patient, the injection speed does not reach the target value immediately after the start of injection due to factors such as the expansion of the drug tube and the viscosity of the contrast medium, and there is a delay until the predetermined speed is reached. It is assumed that it will occur.

  Therefore, when trying to accurately inject a set amount of contrast agent in this method, the time until the entire amount is injected exceeds the initially set injection time, which may affect contrast imaging. is assumed.

  Such a problem can also occur in contrast agent injection in CT examination and MRI examination, but especially in angiography examination using a thin catheter, it is considered that the problem is more likely to occur because of high-pressure chemical injection. .

  The present invention has been made in view of such problems, and the object thereof is, in particular, a chemical solution capable of injecting a predetermined amount of a chemical solution toward a patient within a predetermined injection time set in advance. It is to provide an injection device and a control method thereof.

The control method of the chemical injection device according to one aspect of the present invention for solving the above problem is as follows:
A method for controlling a chemical liquid injector that operates a piston drive mechanism to push out a chemical liquid in a syringe according to a predetermined injection condition, wherein the chemical liquid is at least a contrast agent,
(A1) An input by an operator regarding (i) information on the injection amount of a contrast medium to be injected in that phase and (ii) information on the injection time of that phase for setting injection conditions in a predetermined one phase Accepting steps,
(A2) creating an injection condition based on the input injection amount and injection time information; (a3) starting chemical injection according to the injection condition;
(A4) determining whether or not the injection speed of the contrast medium has reached a predetermined reference value during the liquid injection;
(A5) When the injection speed reaches the predetermined reference value, (i) determining the remaining amount of contrast medium to be injected and (ii) the remaining time until the injection completion time that is initially set;
(A6) calculating a new injection rate for finishing pushing out the contrast agent remaining amount from the syringe within the remaining time based on the contrast agent remaining amount and the remaining time;
(A7) Thereafter, the step of continuing the chemical solution injection according to the new injection rate;
A control method for a chemical injection device having

(Explanation of terms)
In the above invention,
“Accepting input” basically refers to input of information by the operator performing some input operation (for example, numerical input). In addition, the operator stores information stored in advance. This includes input of information by changing, and input of information by confirming information stored in advance by an operator and confirming it without changing.
“Creating an injection condition” includes that an injection condition prepared in advance is confirmed by an operator's confirmation.

The “chemical solution injection device” refers to a chemical solution injection device that injects a chemical solution, and the type of imaging device used together with the chemical solution injection device is not limited at all. That is, a liquid injector used together with an angiographic apparatus, a CT apparatus, an MRI apparatus, an ultrasonic apparatus, an angiographic apparatus, or the like as an imaging apparatus can also correspond to the chemical injection apparatus of the present application. The chemical solution injection device may inject the chemical solution through a catheter.

“Chemical solution” refers to, for example, a contrast agent, physiological saline, or a mixture thereof.
The “infusion protocol” indicates what kind of chemical solution is to be infused, how much, and at what rate. In the present specification, “injection protocol” and “(chemical solution) injection condition” may be synonymous.

A “catheter” is, for example, a length of about several tens of centimeters (for example, 30 cm or more) in a narrow sense, and is introduced into a blood vessel and used for angiography. It includes a type that is about several centimeters and is punctured into a blood vessel such as an arm.

In this specification, the “operator” refers to a person who uses the chemical liquid injector, and is intended to be a doctor or a medical worker, for example.
“Patient” —As used herein, “patient” may be synonymous with “subject”.

"Data"-As used herein, "data" may be synonymous with "information".
“Connection” —In this specification, when a given device is said to be connected to another device, it may be in either a wired connection or a wireless connection.
“Electrically connected” means that components are connected so that electrical signals can be transmitted in one direction or in both directions, and may be in either a wired connection or a wireless connection. . In addition to the components directly connected to each other, the case where the components are indirectly connected via other elements is also included.

The “icon” is (i) one that displays predetermined information and can be selected by the operator, and (ii) only displays predetermined information and is configured to be selectable. Including both those that are not. All or some of the icons displayed on the screen can be selected by touching each display location with a touch pen, an operator's finger, or the like, or with a cursor on the screen.

“Set as injection protocol / injection condition” means that a chemical solution can be injected with the injection protocol (injection condition). As an example, after an injection protocol is set on the apparatus side, injection of a chemical solution is started when there is an input from a doctor or medical staff.

In one embodiment, the “chemical solution injection device” includes the following components:
-Piston drive mechanism-Control unit-Display Here, these components may be provided in any device constituting the chemical liquid injector. That is, when the chemical liquid injector includes an injection head, a console, etc .;
-The injection head may be equipped with a piston drive mechanism, the console may be equipped with a control unit and a display;
A control unit may be provided on both the injection head and the console,
-A display may be provided on both the injection head and the console.

  ADVANTAGE OF THE INVENTION According to this invention, the chemical | medical solution injection apparatus which can inject | pour a predetermined quantity of chemical | medical solutions toward a patient within the predetermined injection | pouring time set beforehand, and its control method can be provided.

It is a block diagram which shows typically an example of the whole structure of the chemical | medical solution injection device for an angiography inspection. It is a schematic diagram which shows an example of the examination room of a medical institution, an investigation room, and a machine room. It is a perspective view which shows the syringe and protective case for an angiography test | inspection. It is a flowchart which shows an example of procedures, such as an injection protocol setting and chemical | medical solution injection | pouring. It is a figure which shows an example of the GUI screen for setting an injection | pouring protocol (setting screen, initial stage). It is a figure which shows an example of the GUI screen for setting an injection | pouring protocol (a setting screen, imaging region selection). It is a figure which shows an example of the GUI screen for setting an injection | pouring protocol (a setting screen and a blood-vessel site | part are selected). It is a figure which shows an example of the GUI screen for setting an injection | pouring protocol (a setting screen and a blood-vessel site | part are selected). It is a figure which shows an example of the screen during chemical | medical solution injection | pouring execution. It is a figure which shows an example of the screen for setting the injection | pouring conditions of an abdominal part. It is a figure which shows an example of the network structure of a medical examination system. It is a figure for demonstrating the set injection | pouring conditions and actual chemical | medical solution injection | pouring. It is a figure which shows the condition change system of one form of this invention, and the speed change after an injection | pouring start. It is an example of the flowchart which performs the speed setting after the condition setting system and injection | pouring start of one form of this invention. It is a figure which shows the various patterns of the injection | pouring speed | velocity after a change. It is a figure which shows the case where the upper limit of injection | pouring speed | rate is detected. It is a figure which shows an example of GUI which can implement | achieve the condition setting system of one form of this invention. It is a figure which shows an example of the image which displays the injection | pouring speed | velocity | rate after an injection | pouring start in real time. It is a block diagram which shows the structure of the chemical | medical solution injection device of the other use which can apply the condition setting system etc. of one form of this invention. FIG. 20 is a perspective view illustrating an example of an injection head, a console, and the like corresponding to FIG. 19.

  Embodiments of the present invention will be described below with reference to the drawings. In the following description, description will be made based on one specific form shown in the drawings, but the specific configuration of each component is not limited to a specific one. Modifications will be described later with reference to other drawings.

  The invention according to one aspect of this application is characterized by, for example, an injection condition setting method and an injection operation shown in FIGS. 12 to 16. First, the configuration of the chemical injection device and the GUI (graphical user interface) The setting method of the injection conditions through this will be described.

[Configuration of chemical injection device]
As shown in FIG. 1, the drug solution injection system 500 of this embodiment includes a drug solution injection device 100 for angiography that injects at least a contrast medium as a drug solution into a patient. The chemical injection system 500 may also include an imaging device 300 that captures a fluoroscopic image of the patient.

  The chemical injection device 100 may include an injection head 110 to which the syringe 200 is attached, a console 150 wired or wirelessly connected thereto, and a power supply unit 148 connected to the injection head 110 and the console 150. .

  In such a configuration, for example, as shown in FIG. 2, the imaging device 300 and the injection head 110 are arranged in the examination room, the console 150 is arranged in the operation room, and the power supply unit 148 is arranged in the machine room. Also good. Each chamber may be partitioned by a wall, and a window may be provided between the examination room and the operation room.

  Regarding the arrangement position of the power supply unit 148, in another form, the power supply unit 148 may be arranged in the operation room. Alternatively, the power supply unit 148 may be disposed in the examination room.

  In addition, it is good also as a chemical | medical solution injection | pouring apparatus with which the injection | pouring head 110 and the console 150 were integrated, or the injection | pouring head 110, the console 150, and the power supply unit 148 were comprised integrally. Such a chemical injection device may be arranged in the examination room. Here, “integrated configuration” does not necessarily mean that all the devices are housed in one housing, and the devices are arranged adjacent to each other and moved integrally by a doctor or medical staff. Such a configuration is also included. For example, it may be a chemical solution injector in which a movable stand is mounted that corresponds to the injection head 110 and the console 150 (and the power supply unit 148 as necessary).

  In another form, the battery electrically connected to the injection head may be mounted on the movable holding means and configured to be freely movable. Further, the battery may be provided with wheels or the like so that the battery can be moved. As an example of the battery, a DC battery can be used.

1. Angiographic Syringe An angiographic syringe 200 is an example, and includes a cylindrical cylinder member 210 and a piston member (plunger) 220 slidably inserted therein. A commercially available syringe 200 may be used as the angiographic syringe 200. The capacity of the syringe 200 may be, for example, about 100 ml to 200 ml.

  The material of the cylinder member 210 may be resin, glass, metal, or the like. The cylinder member 210 may have an open base end, and a cylinder flange 211a may be formed near the base end. The contour shape of the cylinder flange 211a may be any shape, for example, a circle, an ellipse, a polygon, or a part of these shapes (for example, an I cut shape, a D cut) Shape).

  The front end of the cylinder member 210 may be closed, and a long and narrowly protruding conduit portion (nozzle portion) 211b may be formed. A luer lock structure for connecting a chemical liquid tube may be formed at the tip of the conduit portion 211b. The front end portion of the cylinder member 210 may be a flat surface or may have a substantially conical shape protruding toward the front end side.

  The piston member 220 may be a so-called rodless type. A locking protrusion 214 for directly or indirectly connecting the rod or the ram member of the piston drive mechanism may be formed on the back surface of the piston member 220.

  The locking projection 214 may have any shape, but is only an example of a shaft member extending in the axial direction of the syringe and a disk-shaped portion formed at the end of the shaft member. It may have. In another form, it may consist of a pair of L-shaped members arranged on the back surface of the piston member 220 at a predetermined interval. The material of the piston member 220 is not particularly limited, but may be resin, metal, or a combination thereof with rubber.

  In general, the guaranteed pressure resistance of the product is set in the angiographic syringe 200. The guaranteed breakdown voltage may be 1000 psi, for example. The syringe 200 may be distributed as a sterilized disposable product. The syringe 200 may be contained in the packaging bag as a single item or in combination with a predetermined accessory.

  The syringe may be a prefilled type in which a chemical solution is filled in advance, or may be a suction type that sucks and uses a chemical solution in an empty syringe.

2. Protective Case The angiographic syringe 200 may be attached to the injection head 110 in a state of being inserted into the protective case 240 illustrated in FIG. Such a protective case 240 may have a cylindrical hollow body member 241 as an example. The main body member 241 has a configuration in which the front end side is closed and the rear end side is opened. The syringe 200 is inserted from the opening on the rear end side of the protective case 240. An opening 241a for allowing the conduit 211b of the syringe to pass is formed on the closed end surface of the main body member 241. Although not limited, the opening 241a may be formed so as to be positioned at the center of the distal end surface.

  A flange portion 241 b may be formed at the base end portion of the protective case 240. An indicator for discriminating the upper and lower sides of the protective case may be formed on the flange portion 241b. The indicator may be a protrusion, for example. For example, a mark such as “UPSIDE” may be formed on the protrusion. The flange portion 241b is preferably designed in a shape and / or strength suitable for being held by a holding structure (for example, a clamper mechanism) on the injection head side. The material of the protective case 240 is not particularly limited, but may be resin, glass, metal, or the like.

3. Identification member The protective case and / or syringe may be provided with one or more identification members (identification means) for identifying the type of the protective case and / or syringe. The identification means may be a predetermined data carrier member. As the data carrier member, an IC tag, a barcode, a magnetic material, or the like may be used.

The information to be identified or stored may be at least one or a combination of:
(1) Information on the syringe-Identification information of the syringe-Pressure resistance of the syringe-Inner diameter of the cylinder member-Stroke of the piston member, etc. (2) Information on the chemical solution filled in the syringe-Name (for example, product name)
-Component information such as the amount of iodine-Expiration date-Chemical solution volume, etc. (3) Information about the protective case-Identification information of the protective case-Pressure resistance of the protective case, etc. (4) Unique unique ID

4). Extension tube An extension tube is connected to the distal end of the conduit portion of the syringe. If two syringes are used, the extension tube may be a so-called T-tube or Y-tube. As such an extension tube, as an example, a first tube portion extending from the conduit portion of one syringe to the branch portion of the extension tube, a second tube portion extending from the conduit portion of the other syringe to the branch portion, And a main tube portion extending from the branch portion toward the patient.

  Various catheters are exchangeably connected to the distal end side of the extension tube. With the catheter introduced into the patient, the injection head is operated to push out the drug solution in one or more syringes, whereby the drug solution is injected into the blood vessel through the catheter.

  In a scene where chemical liquid is sucked into the syringe, a suction tube for sucking the chemical liquid into the syringe may be attached to the distal end of the syringe conduit section. As the suction tube, for example, the tip side is curved and has a J shape as a whole. You may use with what was formed in.

5. Injection Head The injection head 110 may have a casing having a length in the front-rear direction, and one or a plurality of syringes may be attached to the front end side of the casing. The injection head 110 may be of a single type that holds a single syringe, or may be of a dual (two-cylinder) type that holds two syringes.

  The injection head 110 has one or more piston drive mechanisms 130 and one or more control units 144 electrically connected to them to control the piston drive mechanisms 130. It may be.

(Piston drive mechanism)
The piston drive mechanism includes a motor as a drive source, a motion conversion mechanism that converts the rotational output of the motor into linear motion, and a ram member (pressor member) that is moved by the motion conversion mechanism to move the piston member of the syringe forward or backward. It may have. As such a piston drive mechanism, a known mechanism generally used in a chemical liquid injector can be used. An actuator other than the motor may be used as the drive source.

  Two systems of piston drive mechanisms may be provided according to the number of syringes. In this case, one may be for a contrast medium syringe and the other may be for a saline syringe. Each piston drive mechanism is configured to be able to operate independently, and these can be operated simultaneously or separately according to a control signal from the control unit.

Typical piston drive mechanisms include the following:
-Chemical injection (advance of ram member)
-Chemical suction (retraction of the ram member)
In “chemical solution injection”, a chemical solution is injected in accordance with a set injection protocol (injection condition) by operating the motor in accordance with a predetermined motor control signal and moving the ram member forward.
In “chemical solution suction”, a chemical solution is sucked into a syringe by operating a motor in accordance with a predetermined control signal to retract a piston member.

  In the case of a prefilled syringe, the chemical liquid suction need not be performed.

(Controller unit)
The control unit 144 may include a CPU (Central Processing Unit) that performs arithmetic processing, a memory, an interface, and the like, and may implement various functions by executing computer programs stored in the memory. The control unit 144 may be a one-chip microcomputer that includes hardware such as a CPU, ROM, RAM, and I / F and is equipped with a program.

The control unit 144 is electrically connected to various elements of the injection head described later. The control unit 144 may be configured (programmed) to perform the following processing as an example:
-Perform predetermined calculation processing based on signals from various sensors-Send a predetermined motor control signal to the piston drive mechanism to control the operation-Display predetermined information on a display, etc.-Input of physical buttons, etc. Accept input from the operator through the device-control the operation of the heater, etc.

(Various sensors)
The injection head 110 may have one or more of the following as various sensors 145:
-One or more pressure sensors-One or more syringe detection sensors (magnet sensors, hall sensors, etc.)
-One or more tilt sensors-one or more rotary encoders-one or more motor current detectors, etc.

(A1) Pressure sensor A pressure sensor is for detecting the pressure which pushes a piston member, for example, By this, the pressure estimated value of a chemical | medical solution can be calculated | required. The pressure sensor may be a load cell, for example. The load cell should just be provided in the position which can detect the pressure which the ram member of a piston drive mechanism pushes a piston member.

  For example, when using the load cell detection result to calculate the estimated value of the chemical pressure when the chemical solution is being injected, the calculation is performed in consideration of the needle size, chemical concentration, injection conditions, etc. May be.

  In another aspect, a pressure sensor that directly detects the pressure of the chemical solution may be included.

(A2) Syringe detection sensor The syringe detection sensor is used to detect whether or not a syringe and / or protective case is attached, or to determine what type of syringe and / or protective case is attached. It is what Such a sensor may be either a contact type or a non-contact type. For example, the following can be used:
-Contact sensors using physical contact-Electrical sensors that detect objects electrically-Magnetic sensors-Hall sensors-Optical sensors-Proximity sensors, etc.

(A3) Tilt sensor The tilt sensor detects the tilt of the injection head. In general, this type of injection head performs the suction of the chemical solution into the syringe in such a posture that the front end side (that is, the syringe side) is upward. On the other hand, the chemical liquid injection is performed in such a posture that the front end side of the injection head is relatively downward (a posture in which the tip side is directed slightly downward). By using the detection result of the tilt sensor, it is possible to prevent, for example, chemical liquid suction or chemical liquid injection in an undesirable posture.

(A4) Rotary encoder A rotary encoder or the like for detecting the rotational speed and / or rotational direction of the motor of the piston drive mechanism may be provided.

(A5) Motor current detector It is also possible to calculate the estimated pressure value of the chemical based on the motor current without using a load cell or the like. In this system, the motor current is monitored by the motor current detector during operation of the motor, and the estimated pressure value of the chemical solution is obtained based on the motor current.

(Other components of the injection head)
The injection head may further have one or more of the following:
-One or more syringe heaters (147a)
-One or more head displays (147b)
-One or more head status indicators-One or more manually operated knobs (manual knobs)
-One or more physical buttons (input device, 147c)
-One or more clamp mechanisms-One or more syringe receivers (protective cover receiver)
-One or more RFID communication devices-one or more data receivers-one or more data transmitters, etc.

(B1) Heater The heater is for keeping the chemical solution in the syringe at a predetermined temperature. Any type of heater and heat generation method may be used, but as an example, a sheet-like heater may be used. The sheet-like heater may be provided in the syringe receiving part (protective case receiving part) of the injection head so as to be close to the outer peripheral surface of the protective case.

(B2) Display or the like A display for displaying predetermined information may be provided in the injection head. The display may be provided, for example, in a part of the casing of the injection head. Alternatively, a sub display prepared separately from the housing may be used.

  The display may be a display unit using an LCD (Liquid Crystal Display), an organic EL (Organic Electro-Luminescence) display, or the like, but may be a display unit using an LED (Light Emitting Diode).

The contents displayed on the display are not particularly limited, but may be as follows:
-Predetermined status display during infusion operation-Conditions for injecting medicinal solution-Conditions for injecting medicinal solution-Injected amount of medicinal solution-Pressure of medicinal solution-Injection rate

For example, a predetermined light emitting unit for notifying an operator of a predetermined state of the injection head may be provided in a part of the casing of the injection head. As an example of the light source, an LED (Light Emitting Diode) can be used. Such a light emitting unit has a function as a head status display unit, and can notify the operator of various situations of the injection head by changing a light emission color or a light emission pattern.

(B3) Physical button The physical button is not particularly limited, but may be as follows:
-Advance button for advancing the ram member-Retreat button for retracting the ram member-Accelerator button for increasing the moving speed of the ram member by pressing simultaneously with the advance button or the retreat button-Stop button for stopping the operation of the head ,etc

  These physical buttons can be appropriately arranged on the upper surface, side surface, lower surface, rear end surface and the like of the injection head housing. In the case of a two-cylinder injection head, the physical button arrangement for one piston drive mechanism and the physical button arrangement for the other piston drive mechanism may be asymmetric.

(B4) Clamp mechanism The clamp mechanism is a mechanism that holds the flange portion of the protective case. For example, the flange portion may be held by sandwiching the flange portion from both sides with a pair of holding members. For example, such holding members may each be formed in a substantially arc shape and rotate around a predetermined axis to open and close. In another form, it may have a single member that is pivotally supported around one end and is opened and closed around the shaft, and the flange portion is locked by the member.

(B5) Manual knob The manual knob is for manually moving the ram member forward or backward by operating (for example, rotating) the manual knob. When two piston drive mechanisms are provided, one manual knob may be provided for each piston drive mechanism. The manual knob is an example, and can be arranged at the rear end portion, the side portion, the upper portion, the lower portion, or the like of the injection head.

(B6) RFID communication device When data holding means such as an IC tag is attached to the syringe or the protective cover, a wireless communication device that reads information on the tag may be provided. This wireless communication device may be an RFID reader that simply reads data from an IC tag, or may be an RFID reader / writer that can also write data to an IC tag.

(B7) Data receiver The data receiver is for receiving data transmitted from the outside to the injection head by wire or wireless. For example, the data receiver may receive the following data from the outside:
-Arbitrary data generated by the imaging device-Arbitrary data generated by the hospital system, etc.

(B8) Data transmitter The data transmitter is for sending predetermined data from the injection head to the outside by wire or wireless.

  As a communication protocol for the data receiver and the data transmitter, a suitable protocol may be adopted in consideration of a communication system with another device which is a communication partner. A data transmitter or the like that communicates with an external device may be provided in the console.

The data that can be transmitted from the injection head to the outside by the data transmitter may be one or more of the following:
-Name of contrast medium used, etc. (contrast medium identification information)
-Total amount of contrast medium injection-Contrast medium injection time-Contrast medium injection pressure-Contrast medium injection speed, etc.

And one or more of the following:
-Patient identification information (eg patient ID)
-Inspection identification information (for example, inspection ID)
-Information on imaging time, etc. Such information may be transmitted in combination with the information on the contrast agent described above.

  The injection head 110 and the console (detailed below) are provided with a communication unit (not shown) for communicating with an external device. The piston drive mechanism may be configured to control the operation so as to adjust the injection amount of the contrast agent, the injection speed, and the like according to the injection conditions input from the external device via the communication unit.

(B9) Abnormality detection It is preferable that various types of sensors as described above are used to detect one or more injection abnormalities among the following:
-Abnormal injection due to malfunction of the piston drive mechanism-Abnormal injection due to the syringe not being properly mounted on the injection head-Abnormal injection due to insufficient contrast agent remaining in the syringe to perform the injection operation -An abnormal injection due to a catheter or needle not being inserted into the patient normally-An abnormal injection due to a kink occurring in the middle of the chemical route-The pressure value of the detected chemical is within a predetermined range (upper and Injection range that is not within a predetermined range with a lower limit, or a predetermined upper limit, a predetermined lower limit, etc.

-At the time of chemical | medical solution injection | pouring, for example, when the chemical | medical solution path | route is clogged, the drive force of a piston drive mechanism will exceed a predetermined range. On the other hand, when the injection needle is removed from the patient, the driving force falls below a predetermined range. By seeing such a change in driving force, it is possible to detect whether or not the chemical solution is normally injected.
-When it is detected by the sensor that the predetermined amount of the chemical is not normally loaded, the detection result may be transmitted to the outside from the communication unit.
-In addition, for example, a pressure sensor for measuring pressure may be provided in the middle of the extension tube to detect whether the chemical solution is injected at a predetermined pressure.

6). As shown in FIG. 1, the console 150 includes one or more displays 151, one or more control units 153, various input devices (157a to 157c), and the like. Although the physical form of the console 150 is not specifically limited, For example, you may have a 1 or several housing | casing. As an example, the control unit 153 may be disposed in one housing, and the display 151 may be disposed on the front surface of the housing.

However, the form of the housing is not limited at all. It is good also as a preferable housing | casing shape suitably according to the scene where the console 150 is used. For example, it may be:
-A stationary housing shape suitable for use on a table;
-A casing shape that can be suitably attached to a predetermined support member or a wall (for example, a thin casing having a substantially flat back side), and the like.

  The display of the console may be a display unit using an LCD (Liquid Crystal Display), an organic EL (Organic Electro-Luminescence) display, or the like. A touch panel display may also be used. The touch panel display serves as both a display device and an input device.

(Controller unit)
The control unit 153 includes a CPU (Central Processing Unit) that performs arithmetic processing, a memory, an interface, and the like, and implements various functions by executing computer programs stored in the memory. The control unit 153 may be a one-chip microcomputer that includes hardware such as a CPU, ROM, RAM, and I / F and is equipped with a program.

The control unit 153 has a number of functions in accordance with the installed program, and examples of the console functions include the following:
-Injection protocol setting GUI display function-Injection protocol setting function-Screen display function during injection-Screen display function after injection-Input detection function-Injection control function, etc.

  The computer program may be stored in advance in a predetermined storage area of the console, downloaded from the outside through a network or the like and stored in the predetermined storage area, or It may be read from an information storage medium inserted into the slot.

  The above functions are configured in the control unit by a computer program, respectively, injection protocol setting GUI display unit, injection protocol setting unit, screen display unit during injection, screen display unit after injection, input detection unit, injection control It may be realized by the unit.

  The injection protocol setting GUI display function displays a GUI screen for setting the injection protocol on the display. Specifically, a body segment icon, an imaging region icon, a blood vessel site icon, and the like are displayed. When the blood vessel site icon is selected, a predetermined liquid injection condition is presented on the display. The injection protocol setting function sets the content as an injection protocol after the medical solution injection conditions presented as described above are confirmed / corrected by a doctor or a medical staff. The screen display function during the injection displays a still image or an animation image on the display during the injection of the chemical solution. Further, during the injection of the chemical liquid, the pressure information of the chemical liquid is displayed on the display. The post-injection screen display function displays information related to the implemented chemical solution injection on the display. The input detection function accepts an input from a doctor or medical staff performed through a touch panel, a physical button, or the like (an example). The injection control function operates the piston drive mechanism in accordance with the set injection protocol to inject the chemical solution. Only one of the piston drive mechanisms may be operated, and both may be operated simultaneously.

The control unit 153 may further have the following functions:
-Injection history generation function-Injection history output function

The injection history generation function is a function for generating injection history data. The “injection history data” may be, for example, one or more of the following:
-Injection work ID that is unique identification information for each injection work
-Date and time of injection start and end-Identification information of the chemical solution injection device-Identification information of the chemical solution and imaging part that are the injection conditions described above

  The format of the data may be a text data format. Alternatively, the format of the data may be DICOM (Digital Imaging and Communications in Medicine) standard method and / or HL7 standard (Health Level 7 standard) which is a standard for medical information exchange.

  The injection history output function may correspond to a function of transmitting injection history data to the outside. Specifically, data may be transmitted to a predetermined external device and / or network. Not only the injection history data, but also, for example, chemicals obtained from an IC tag of a syringe or a protective case, syringe, or protective case data may be transmitted to the outside.

(Input means / input device)
The console 150 may include, for example, a hand switch 157a, an operation button 157b, a slot 157c, and the like as input means.

  The hand switch 157a is connected to the console by wire or wirelessly and is operated by the operator, and may have a push button type switch or the like.

  The operation button 157b may be, for example, one or a plurality of physical buttons provided on the housing of the console 150. For example, these physical buttons may be provided on the front surface of the housing.

  The slot 157c is a portion into which a predetermined information storage medium is inserted, and the console can read predetermined data from this information storage medium.

  Although not limited thereto, a foot switch 157d (see FIG. 2) is connected to the power supply unit 148, and the operation of the injection head 110 and / or the console 150 is controlled by operating the foot switch 157d. It may be configured.

  Note that the foot switch 157d may be connected to the console 150 in another form. Alternatively, the foot switch 157d may be connected to the injection head 110.

(Other components of the console)
The console may have a speaker or the like (not shown) for outputting sound and / or sound.
The console may have a microphone or the like (not shown) for inputting voice.

7). Imaging Device As the imaging device 300, for example, a conventionally known angiography device or the like can be used. The imaging apparatus 300 includes an imaging unit 304 including a C-arm that performs imaging of a predetermined blood vessel site of a patient lying on a bed, a control unit 303 that controls the imaging unit 304, and one or a plurality of interpretation monitors 305. There may be.

  The C-arm may be provided with an X-ray tube at one end and an FPD (Flat Panel Detector) at the opposite end. It may be an angiographic device having one or more C-arms. As the image interpretation monitor 305, for example, four or six monitors may be arranged side by side. The image interpretation monitor 305 is an example and may be arranged in the examination room.

  The imaging device and the chemical solution injector may be connected to each other by wire or wireless, and may be configured to perform data communication using a predetermined communication protocol. It is also preferable that the imaging device and the chemical solution injector be configured to be interlocked. That is, even if the predetermined operation of the chemical injection device is used as a trigger, the predetermined operation of the imaging device may be performed simultaneously with the operation or at a predetermined time interval with respect to the operation. Good. On the contrary, the predetermined operation of the chemical injection device is configured to be performed at the same time as the trigger of the predetermined operation of the imaging device or at a predetermined time interval with respect to the operation. Also good.

  In the case of angiography, since the contrast medium is injected with the catheter tip reaching the vicinity of the target blood vessel site, as soon as the chemical solution injection device is operated and the piston member is advanced, it enters the target blood vessel. Contrast agent will be sent. Therefore, in general, the imaging device and the chemical solution injection device are interlocked so that imaging can be performed at an appropriate timing.

  As an example of a communication protocol for realizing the above-described linkage, a CANopen protocol based on CAN (controller area network) may be used.

8). Setting of Injection Protocol Next, an example of setting of the injection protocol in the chemical solution injection device 100 of the present embodiment will be described with reference to FIGS.

  5 to 8 are mainly for explaining the procedure for the operator to set the injection protocol through the GUI displayed on the display. Here, as an example, "injection speed" and "injection amount" Although a method for determining a parameter is depicted, even in a method for preferentially determining an “injection time” and an “injection amount” described later, conditions can be input using such a GUI.

(Step S1)
First, for example, when the operator performs a predetermined input operation on the console 150, a screen as shown in FIG. 5 is displayed on the display 151 (step S1). The “predetermined input operation” may be, for example, pressing a physical button or the like on the console to start using the console 150.

  As shown in FIG. 5, this GUI screen may include, for example, a horizontally long display area 721 that is a space for displaying predetermined information, icons, and the like at the top of the screen. Such a display area 721 may be displayed not on the upper part of the screen but on the side part, the lower part, or the like. Further, the display is not limited to the horizontally long shape, and may be a rectangular shape, a vertically long shape, a polygonal shape, or the like.

  As shown in FIG. 5, the GUI screen may include a remaining amount display unit 725 that indicates the remaining amount of the chemical solution in the attached syringe. The remaining amount display portion 725 is displayed on any of the upper left portion of the screen, the upper middle portion of the screen, the upper right portion of the screen, the middle left portion of the screen, the middle portion of the screen, the middle right portion of the screen, the lower left portion of the screen, the middle portion of the lower portion of the screen, and the lower right portion of the screen. In this example, it is displayed on the upper right side of the screen.

  As shown in FIG. 5, the GUI screen may include a human body image 701 in which a plurality of body segment icons 701a to 701d are displayed in a humanoid shape as a whole.

  In this example, the front view shape of the human body is an image displayed in the horizontal direction (horizontal direction), but in another form, the image may be displayed in the vertical direction (vertical direction). Moreover, you may make it display not the front view shape but the side view shape of a human body in a horizontal direction or a vertical direction. Such a human body image may have any size with respect to the size of the screen. For example, in the case of the example in FIG. 5, the entire length (corresponding to the height) with respect to the screen size (width). (Length) may be 50% or more.

  Such a horizontal human body image 701 may be displayed near the center of the screen, at a position above the center, or at a position below the center, but in this example, it is above the center. It is displayed at the position. When the human body image is a vertical type, the human body image may be displayed in any of the vicinity of the center of the screen, the position on the left side of the center part, or the position on the lower side of the center part.

  The plurality of body division icons 701 may include a head 701a, a chest 701b, an abdomen 701c, and a lower limb 701d. Only some of these may be displayed. Moreover, it is good also considering the arbitrary multiple of these as one display.

(Step S2)
Hereinafter, a case of a chest technique will be described as an example.

  When the chest body division icon 701b is selected on the GUI screen of FIG. 5, as shown in FIG. 6, for example, the division is highlighted (inverted display state), and a mark indicating the heart is displayed. Is done.

In addition, a plurality of blood vessel site icons 703a to 703c corresponding to the selected chest (heart) 701b are displayed. The blood vessel part icons 703a to 703c may be the following examination parts:
-LVG: Left Ventricle
-LCA: Left coronary artery (LCA)
-RCA: Right coronary artery (RCA)

  The contents of the icons 703a to 703c are not necessarily limited to the blood vessel site. In other forms, it may be a contrast region or an imaging technique name including an organ name or the like.

  The plurality of blood vessel site icons 703a to 703c may be displayed on the upper side, the lower side, the right side, or the left side of the human body image 701. In this example, the blood vessel site icons 703a to 703c are displayed on the lower side.

  In this way, when the icons 703a to 703c are displayed below the human body image 701, the operator can operate the body segment selection and the subsequent blood vessel site selection as a series of flows, in other words, There is an advantage that the operation is easily performed on the GUI. Furthermore, as will be described later, in this embodiment, the parameters of the injection conditions may be displayed below the icons 703a to 703c. In this case, there is an advantage that operations such as selection of a body segment, selection of a blood vessel region, and subsequent parameter correction can be easily performed as a series of flows.

  The plurality of examination region icons 703a to 703c may be displayed side by side in either the vertical direction or the horizontal direction, but in this example, they are displayed side by side in the horizontal direction.

  More specifically, it is also preferable that the display order of the blood vessel site icons 703a to 703c is displayed so as to correspond to a general routine of angiography (detailed later). Here, the icons are arranged in the order of LVG, LCA, and RCA. This means that a general routine in this angiography is in the order of LVG, LCA, and RCA.

  Of course, the doctor can perform the examination without being restricted in the order, and may perform angiography other than these.

  In the case of the chest, when the body classification icon 701b, which is the above item, is selected, the blood vessel site icons 703a to 703c, which are subordinate items, are displayed. An imaging region icon which is a middle item (details will be described later with reference to FIG. 10) are displayed, and thereafter, a blood vessel part which is a lower item is displayed in order.

(Step S3)
When, for example, the LVG icon 703a is selected on the screen of FIG. 6, an injection condition 715 preset for LVG (left ventricular contrast) is displayed on the screen, as shown in FIG. When the LVG icon 703a is selected, the icon 703a may be highlighted (inverted display state). Further, the selected icon 703a may be displayed in a size slightly larger than the other icons 703b and 703c.

Injection conditions include, but are not limited to, some or all of the following:
-Injection speed-Injection volume-Delay-Pressure limit-Rise time

The “injection rate” is an injection rate of a chemical solution, and its unit is, for example, [ml / sec].
“Amount” is the amount of drug solution to be injected, and its unit is, for example, [ml].
The “delay” is a time difference between the injection start time of the chemical solution and the imaging start time by the imaging apparatus, and its unit is [sec] as an example. There are cases where imaging is started after a lapse of a predetermined time from the start of chemical liquid injection and cases where imaging is started from a predetermined time before the start of chemical liquid injection.
The “pressure limit” is an upper limit value of the pressure of the drug solution to be injected, and is determined based on the type of catheter used. The unit is, for example, [psi], [kg / cm ² ], [MPa] or the like.

  In this example, the above parameters may be displayed as icons. Some or all of these icons may preferably be adapted so that the operator can select them and modify the values.

  For example, when an icon is pressed, a numeric keypad image, an image button for increasing / decreasing a value, or a combination thereof may be displayed, and a doctor or a healthcare worker may change the value by operating such an image. .

  The numerical value may be corrected by the voice input function. The voice input function can be realized by using, for example, a microphone provided in the injection head or console and a voice recognition function provided as one of the functions of the control unit of the injection head or console.

  When using speech recognition in this way, the following advantages are obtained. That is, in angiography, a doctor operates a catheter, but according to voice recognition, there is no need to touch a physical button, a touch panel, or the like for input operation, which is hygienic.

  In another form, a gesture recognition function for recognizing a human movement (such as a gesture) in a non-contact manner may be used. The gesture recognition function may be realized by image recognition means such as a camera, and a gesture analysis function provided as one of the functions of the injection head or the control unit of the console.

  Referring to FIG. 7 again, a standby icon 721a is displayed in the display area 721 on this screen. Although not limited, the standby icon 721a may be displayed at a timing when the predetermined blood vessel site icons 703a to 703c are selected, for example.

(Steps S4 to S6)
In the screen of FIG. 7, for example, after the doctor or medical worker confirms the injection conditions (step S4) or after the doctor or medical staff changes the injection conditions as necessary (step S5), the standby icon By pressing 721a, an injection protocol is set, and a state in which chemical injection can be performed with the injection protocol is established. When the standby icon 721a is pressed, the display in the icon may be switched to “Start OK” as shown in FIG.

  Although not limited thereto, the injection may be started by pressing the standby icon 721a once again.

(Step S7)
After the display on the screen is switched to “Start OK” as described above, a medical solution injection according to the set injection protocol is performed by a doctor or a medical worker performing a predetermined input. Examples of the “predetermined input” include the following:
-Operation of the hand switch-Predetermined operation on the linked angiographic imaging device

  Although not displayed on the screen of FIG. 8, a “return” icon (not shown) for returning from the screen of FIG. 8 to the screen of FIG. 7 is displayed on the screen in order to recorrect the injection conditions. It may be.

  During the injection of the chemical solution, for example, an image indicating that the injection is being performed as shown in FIG. 9 may be displayed. In this example, a human body image icon 721b that can confirm the currently selected body segment is displayed in the display area 721 at the top of the screen. Regarding the human body image icon, the selected part may be highlighted (inverted display state) so that the selected part can be easily seen. Information on the current blood vessel site (“LVG”) is also displayed. For example, the information of “LVG” may be displayed in the display area 721 as character information.

  In another form, this “LVG” information may be displayed at an arbitrary position outside the display area 721 on the screen. Not only character information but also images such as symbols may be displayed.

  In the display area 721, characters “injection” indicating that the injection is chemical injection may be displayed.

  In the screen of FIG. 9, the syringe image 716a and a plurality of droplets drawn so as to be ejected from the syringe tip so that the doctor or medical staff can visually confirm that the medical solution is being injected. An image 717a may be displayed. The droplet image 717a may be configured to be displayed as an animation during the injection of a chemical solution. As an example of the animation display, the color of each droplet is changed stepwise over time, It may be such that it can be visually understood that it is pushed forward.

  On the screen of FIG. 9, information (speed, amount, delay time) of chemical solution injection conditions, information (elapsed time, remaining amount of chemical solution), etc. during the chemical solution injection may be displayed. In the screen of FIG. 9, a pressure display window 713 for displaying the pressure during the chemical injection may be displayed. In the pressure display window 713, a pressure display portion 713a including a plurality of segments is displayed, and the color of the segments changes according to the pressure. Information such as 600 [psi], 800 [psi], and 1200 [psi] may be displayed on the upper portion of the pressure display portion 713a. In addition, a pressure limit display 713b may be displayed so that it is easy to visually confirm how much the pressure limit is. The pressure limit display 713b may be a graphic display such as a triangular shape or an arrow shape. Good.

When it is necessary to interrupt the chemical injection or injection, for example,
-Release the hand switch operation (for example, pressing)-Cancel the foot switch operation (for example, pressing)-Press any button on the injection head-Press the console stop button (example) May come to a stop.

  An example of a hand switch may be one in which a start button for starting an injection operation and a stop button for stopping an injection operation are separately provided on a casing held by an operator. Good. Alternatively, it may be operated by switching on / off of one button, or may generate an input signal only while one button is pressed.

(Abdominal angiography)
Subsequently, abdominal angiography will be described with reference to FIG. For the abdomen, head, lower limbs, etc., it is basically possible to set the injection protocol and perform the chemical injection in the same manner as the chest described above. However, in this embodiment, for the abdomen, imaging region icons 702a to 702c, which are intermediate items such as “abdominal artery”, “kidney”, and “liver”, are first displayed, and one of them is selected. The blood vessel site icons 703a to 703c corresponding to the imaging region are displayed.

  The imaging region icon is not particularly limited, and may be, for example, the celiac artery (702a), the kidney (702b), the liver (702c), or the like. Each of the icons 702a to 702c may be displayed in a graphic form that schematically represents each organ or blood vessel, so that a doctor or a medical worker can easily select visually.

  The three icons 702a to 702c may be displayed so as to overlap the selected body segment icon (here, the abdomen, icon 701c). Three icons 702a to 702c may be displayed so as to fit within the selected body segment icon, but as shown in FIG. 10, within a slightly larger area (refer to the alternate long and short dash line) than the selected body segment icon. It may be displayed.

  Regarding the display of the region indicated by the one-dot chain line, the region may be displayed in an opaque color, for example, or may be a semi-transparent color (therefore, the body segment icon is partially visible). Furthermore, the edge portion of the region may be displayed in a gradation (lighter as it is closer to the edge). In the example of the figure, the alternate long and short dash line is displayed in a rectangle, but a display mode in which the corner is rounded may be used.

  The color is not limited at all and can be set freely. For example, the alternate long and short dash line portion may be blue, and the unselected icon may be white.

  If any one of the icons 702a to 702c is selected, the selected icon is highlighted so that it can be seen at a glance that the icon is selected. Good. As a specific example, there is a display mode in which the selected icon changes from white to blue, and the background image of the alternate long and short dash line switches from blue to white.

  By selecting any one of these icons 702a to 702c, one or a plurality of blood vessel site icons 703a to 703c corresponding thereto are displayed. Subsequent injection protocol settings for each angiography, execution of medicinal solution injection, display of injection results, etc. can be carried out in the same procedure as described above, so detailed description is omitted. It shall be.

In the example of FIG. 15, as a matter of course, the display number of the imaging area icons 702 a to 702 c may be increased or decreased. Further, the imaging region icons 702a to 702c are not limited to this, and may be changed as appropriate. In other aspects of the invention, the following changes may be employed with respect to the imaging area icon:
-An imaging region icon representing an organ or the like included in the body segment is also displayed in a body segment other than the abdomen (head, chest, and lower limbs), and by selecting one of them, a corresponding blood vessel region icon is displayed. Is displayed,
-If multiple imaging area icons are displayed, display them in the order according to the routine of the examination;
-In the above description, it has been described that the imaging region icon is selected after the body segment icon is selected. However, a GUI screen may be used in which the body classification icon is not displayed and the imaging region icon is displayed from the initial screen. Even in this case, after the imaging region icon is selected, a predetermined blood vessel site icon is displayed, and a predetermined injection condition registered in advance is displayed by selecting the blood vessel site icon.

  According to the injection protocol setting method as described above, in order to set an injection protocol for various blood vessel sites, the following procedure can be used instead of selection from a memory list as in the prior art. That is, first, a target body segment icon (imaging segment icon if necessary) is selected on the GUI of the display, and then a blood vessel region icon is selected. As a result, a predetermined injection condition registered in advance corresponding to the blood vessel site is presented, so that the injection protocol can be set by confirming this or correcting as necessary.

  In the conventional method of selecting one condition from the memory list, each condition in the memory list is not grouped for each part, or the condition in the list is simply numeric data, and the condition you want to select It sometimes took time and effort to pick out. However, according to the method as in the present embodiment, a group such as a body segment or an imaging region is first selected, and then a blood vessel part is selected. Therefore, for example, another blood vessel part (for example, the blood vessel part of the head) that is completely unrelated to the current examination (for example, the chest) is not selected. Moreover, since the body section, the imaging region, and the blood vessel part can be selected by selecting an icon, the selection can be performed intuitively with good operability.

  Next, an example of setting injection conditions and an injection operation in the chemical injection device 100 according to one embodiment of the present invention will be described with reference to FIGS. 12 to 18 and particularly along the flowchart of FIG.

  First, in step S11 of the flowchart, injection conditions are set. This setting can be performed, for example, through a GUI displayed on the console display. Specifically, for example, the operator inputs information on “injection amount (ml)” and “injection time (sec)”. The GUI may be anything, but may include a window or icon for inputting information on the injection amount and a window or icon for inputting information on the injection time. A more specific GUI example will be described later with reference to other drawings.

  Next, the console calculates the injection rate (ml / sec) based on the input information on the injection volume (ml) and the injection time (sec). FIG. 12A shows an example of an injection pattern when the injection amount is 20 ml and the injection time is input as 5.0 sec. In this case, the injection speed is set to 4.0 ml / sec. The Rukoto.

-It should be noted that the determination of actual injection conditions takes into account various factors such as the region to be imaged and the patient's weight. As in the above-described embodiment, time-amount information may be programmed in advance corresponding to the part to be imaged. In this case, it is possible to omit the numerical values of the injection amount and the injection time by the operator. Of course, the console (or other control unit) is also preferably configured to accept input for correction and / or confirmation by the operator.
-For convenience of explanation, the pattern in FIG. 12 (A) is a very simplified injection pattern. However, instead of such a simple rectangular injection pattern, the rise in velocity immediately after the start of injection is made smooth. Such subfunctions may be provided. That is, by this sub-function, for example, the time to reach a predetermined target speed after the start of injection is set as 0.5 seconds, 1 second, 1.5 seconds, 2 seconds, etc. (The injection pattern is not rectangular but has a shape that is substantially trapezoidal on one side). The curve for “smoothing the rising edge” may be a linearly increasing curve, a curvedly increasing curve, or a combination thereof.
-In Fig. 12, only a single contrast agent injection phase is depicted, but of course one or more additional injection phases (contrast agent, saline or their simultaneous injection) are used. Also good.
The injection conditions as described above may be visualized on a display, for example, in a graph-like manner as shown in FIG. 12, but are not essential.

  Returning to the description of the flowchart of FIG. 14 again, after the injection conditions are set by the operator, the injection is started in step S12. For example, when a predetermined injection start button (not shown) is operated by the operator, the drive source (motor) of the piston drive mechanism 130 is controlled in accordance with the set injection conditions, and the liquid medicine is pushed out from the syringe.

  During the injection of the chemical liquid, in step S13, the chemical liquid injection apparatus 100 monitors the output of, for example, a motor encoder (not shown), and determines whether or not the rotational speed of the motor has reached a predetermined rotational speed. It may be a thing. If it is determined in step S13 that the motor has reached a predetermined rotational speed, that is, if it is estimated that the chemical solution injection speed has reached a predetermined value, the process proceeds to the next step. Here, it is assumed that a predetermined injection rate is reached at time t1.

  In step S14, the remaining time (see FIG. 13) from time t1 to injection completion time t2 is obtained. Further, the remaining injection amount of the chemical solution to be injected is obtained. The “remaining time” may be obtained, for example, by calculating (t2−t1). The “injection remaining amount” may be calculated based on, for example, information on the amount to be injected (for example, 20 ml in this case) and information on the amount injected by time t1.

  The “information on the amount injected by time t1” may be calculated based at least on the amount of movement of the ram member of the piston drive mechanism (in other words, the amount of advancement of the piston member of the syringe). Any information indicating the amount of movement of the ram member may be used. For example, information on the number of rotations of the motor after the start of injection or an actual ram member (or piston detected by a predetermined detector) can be used. Information on the amount of movement of the member may be used.

  Thereafter, in step S15, a new injection rate (4.5 ml / sec) is calculated based on the “remaining time” (eg, 4.0 sec) obtained in the above step and the “injection remaining amount” (eg, 18 ml). Set.

  Then, as shown in FIG. 13, thereafter (t1-t2), the chemical solution injection is continued at a new injection rate (4.5 ml / sec) (step S16). The chemical solution injection is completed when the initially set injection completion time t2.

  In the chemical solution injection method as described above, the entire injection amount initially set can be injected toward the patient by the injection completion time t2. That is, in the method in which the injection conditions are set based on the “injection rate” and the “injection amount”, the injection rate in the injection process is constant even when a delay occurs until the injection rate reaches a predetermined value. Therefore, in order to inject a chemical solution corresponding to the delay, the injection time (t2 ′: t2 + α [sec]) is increased as shown in FIG.

  On the other hand, according to the injection method as in the present embodiment, it is possible to finish pushing out a predetermined amount of drug solution by the initially set injection completion time t2), so that the contrast effect at the timing desired by the doctor can be obtained. can get. Further, from the viewpoint of cooperation with other imaging devices and the like, according to such a method, it is possible to finish extruding the contrast medium within a predetermined injection time, so that the time for the contrast medium to reach the region of interest is greatly increased. Therefore, a good imaging result by the imaging device can be obtained.

  In the above description, the new injection rate at the time (t1 to t2) is constant, but the present invention is not necessarily limited to this, and various injection patterns can be adopted as follows.

  FIG. 15A shows a constant new injection rate after time t1, as described above.

  FIG. 15B shows an example in which there is a velocity peak in the first half between times t1 and t2. In this example, specifically, until time t1 ′, the injection rate monotonously increases (may be linear or curvilinear) with the passage of time, and thereafter the passage of time. At the same time, the injection rate decreases monotonously (may be linear or curvilinear).

  The peak time t1 ′ may be in the first half of the middle of the times t1 to t2, may be substantially in the middle, or may be in the second half.

  FIG. 15C shows an example in which the injection rate changes stepwise with time. A plurality of phases of two, three, four, five or more are set at times t1 to t2. The injection rate in each phase may be constant or may increase or decrease with time. FIG. 15C shows an example in which the speed peak is in the first half between times t1 and t2, but a pattern in which the speed peak comes in the second half as shown in FIG. .

(Detection of upper limit of injection rate)
As shown in FIG. 16, when a new injection rate is calculated after time t1 (here, a pattern as shown in FIG. 15B is illustrated), the calculated new rate is a predetermined rate set in advance. A step of determining whether or not the upper limit value Vmax is exceeded may be performed. For example, depending on the site where the contrast medium is injected, the catheter used, etc., if the injection speed is too high, there is a possibility that blood vessels or organs may be damaged, or the catheter tip may move vigorously in the body. Therefore, in such a case, the calculated speed may be compared with the speed upper limit value Vmax so that the set injection speed does not exceed it. By doing so, the above problem can be prevented.

  Such a determination may be automatically performed by the console 150. The console 150 may be configured to issue an alert when the upper limit is exceeded. As an aspect of the alert, a message, an icon, or the like may be displayed on the display. In addition, or separately, a sound or voice alert may be issued. The console 150 may be configured to set the injection rate within a range that does not exceed the upper limit value.

  The speed upper limit Vmax (speed limit) in the above can be set as appropriate from various viewpoints. As an example, the pressure of the chemical solution assumed when injecting at the speed is a predetermined upper limit (pressure limit). ) It may be set to the following value. In other words, a speed that does not exceed the set maximum pressure may be automatically set.

(Injection condition record)
According to the embodiment as described above, the injection condition of the chemical liquid once set by the operator is automatically changed by the apparatus according to the actual situation of the chemical liquid injection. Therefore, the chemical solution injector may be configured to store the data of the performed injection conditions (for example, an injection pattern as shown in FIG. 13) in a predetermined storage area.

  As an example, data may be stored in a storage device such as a hard disk or memory provided in the console. Alternatively, the chemical solution injection device may have a mechanism for transmitting such data to the outside. For example, a configuration in which data is transmitted to other medical devices and / or computers via a wired or wireless LAN and stored in the medical devices and / or computers is also conceivable. Data may be sent to other medical devices and / or computers via a communication network such as the Internet, not limited to a LAN.

(Example of GUI)
When the above injection condition setting method is used in an angiographic examination console, for example, a GUI as shown in FIG. 17 can be used. This GUI is basically similar to that shown in FIGS. 10 and 8, but when a predetermined site icon (for example, 703a) is selected, a pre-programmed injection volume (6 ml) and injection time are used. (3.0 sec) is automatically displayed, and the injection rate (2.0 ml / sec) calculated based on them is displayed.

  Here, each of the injection amount and the injection time may be configured such that numerical values can be changed. For example, when an icon is selected, a numeric keypad appears and a numerical value may be input by operating it. Further, it may be configured such that the numerical value can be increased or decreased by a cursor or the like.

  Further, it is also preferable that the console 150 has a voice recognition function so that the voice of the operator can be recognized by voice recognition to input, change and / or confirm data.

  In the above-described chemical liquid injection, as described above, the injection speed changes during the injection. Therefore, as shown in FIG. 18, a speed indicator 715v is displayed on the display, and the speed indicator 715v may be configured to indicate the current injection speed in real time. The speed indicator 715v may be any image, but may be, for example, a plurality of segments arranged.

9. Medical Examination System The chemical solution injection system according to one aspect of the present invention may constitute a part of a medical examination system. FIG. 11 is a diagram schematically illustrating an example of a medical examination system. This medical examination system includes the following components connected on a network:
-Chemical injection system 500
-Hospital Information System HIS (Hospital Information System) 901
-Radology Information System (RIS) 902, which is a radiology information system
-PACS (Picture Archiving and Communication Systems) 903 which is an image storage server
An image viewer 904 which is a data processing device
A printer 905 for outputting information, etc.

  The above configuration is merely an example, and all illustrated elements are not essential to the present invention.

  Each device may be connected through a communication line such as a LAN (Local Area Network), a dedicated line, and an Internet line. The medical examination system may be compliant with DICOM (Digital Imaging and Communications in Medicine) which is a standard for digital medical images.

The control unit of the imaging device may have at least one of the following functions, for example:
-Giving identification information (image ID) to the acquired image;
-Add imaging time information to the acquired image,
-Send the patient's fluoroscopic image data to the outside,
-Sending the exposure time data for the fluoroscopic imaging (one examination) performed to the outside,
-Sending exposure data to the outside in the fluoroscopic imaging (one examination) performed,
-Send identification information of the fluoroscopic imaging performed to the outside,
-Send any data to at least one of HIS, RIS, PACS,
-Send any data to the chemical infusion device,
-Send any data to the image viewer,
-Send arbitrary data to the printer.

  The HIS 901 is an in-hospital system that integrates an electronic medical record system, an order entry system, an inventory management system, a medical accounting system, and the like. However, some of these may be constructed as a system independent of the HIS.

  The accounting system may handle, for example, examination costs received by patients in a hospital where the system is installed. The inventory management system may manage, for example, inventory of members consumed by the imaging device and members consumed by the chemical solution injector (for example, a contrast medium syringe, a physiological saline syringe, etc.).

For example, the RIS 902 may manage imaging order data for imaging a patient. This imaging order data may include at least one of the following information, for example:
-Imaging work ID which is unique identification information
-Identification information of fluoroscopic imaging device-Identification information of patient-Date and time of imaging, etc.

The PACS 903 is for storing the fluoroscopic image data of the patient. The PACS 903 is an example and may be configured as a database server in which a dedicated computer program is installed. The PACS 903 may have at least one of the following functions:
-Save the image data received from the imaging device-Send the predetermined data stored to the workstation (image viewer)-Save to the connected predetermined image browsing device (not shown) Send certain data, etc.

  The image viewer 904 may be configured as a workstation by way of example, and may be used for browsing a fluoroscopic image, for example.

  This workstation is composed of a computer or the like as an example. Specifically, the workstation may include a computer body, a control unit provided therein, a storage device, a display device, an input device, and the like. Good. The arrangement position of the control unit and the storage device is not particularly limited, and may be arranged inside or outside the computer main body. The display device is controlled by the control unit to display various data such as inspection data and captured images. The display device is composed of, for example, an LCD (Liquid Crystal Display). Examples of the input device include arbitrary devices such as a keyboard, a mouse, a trackball, and a joystick. When the display device is a touch display, the touch panel display also serves as an input device. The storage device stores various data. The storage unit device may include a storage device such as a hard disk drive.

  In other forms, the image viewer may be a portable device such as a tablet terminal. In this portable device, a processor unit, a memory, a storage device, and the like are built in a housing, and predetermined information is displayed on a touch panel display, for example.

  The printer 905 is connected to each device in the system via a network. For example, it may be configured such that predetermined information can be printed out on a paper medium in response to a command from a device provided in the chemical solution injection system 500. In another embodiment, for example, a predetermined information may be printed out on a paper medium in response to a command from the image viewer 904.

Connection of the printer 905 to the network or connection to another device may be either wired or wireless. For printer use, for example:
-The injected result may be printed out.
-A graph or numerical data of injection conditions actually used in the "time" / "amount" priority injection method as shown in FIG. 13 may be printed out.

For medical inspection systems, for example:
-The injected result may be associated with the chart information via the network. Specifically, for example, the drug request may be surely performed by such association. Also, a contrast agent administration history may be stored as part of angiographic recording.
-By entering the network, one or more of fluoroscopic images, body monitor information (catelaboratory), and injection information can be grasped centrally on the monitor, and comprehensive judgment of treatment and image diagnosis can be performed quickly and reliably.

(Application example of contrast agent information)
Further, regarding the HIS inventory management system, the following configuration may be adopted. That is, in the inventory management system, (a) how much contrast medium is used and how much the contrast medium is in stock, and / or (b) predetermined contrast based on the situation It may be automatically determined by the system whether or not the agent needs to be replenished.

  The determination as described above is, for example, information such as the name of the contrast agent (contrast agent identification information), the total injection amount of the contrast agent, the injection time of the contrast agent, and the injection rate of the contrast agent (injection speed per unit time). May be performed based on the above. Information regarding such a contrast agent may be transmitted directly from the drug solution injector to the HIS, or may be transmitted via one or more other devices.

(Use example of inspection information)
Further, regarding the information on the catheter used in the examination, the following configuration may be adopted. That is, information on one or more catheters used in the examination may be stored in a predetermined storage area in the medical examination system. For example, the following can be used as information about the catheter:
-Type of catheter (identification information)
-Size information such as diameter (French) (catheter thickness information)
-Number used, etc.

  The catheter information may be stored in a table format such as a catheter name table. Moreover, the information on the catheter may be stored in association with the information on the chemical liquid injector used in the examination, for example. In addition, the catheter information may be stored in association with the information of the performed infusion protocol.

  As a chemical | medical solution injection | pouring apparatus, you may be comprised so that the information (tabular form in an example) regarding the correlation with such a catheter and an injection | pouring protocol may be displayed on a 1 or several display. In addition, when a predetermined infusion protocol is selected, a catheter associated with the infusion protocol (for example, a catheter recommended for the infusion protocol or a catheter used in the last infusion protocol) is displayed on the display. It may be configured as follows. This allows the physician or health care professional to know which catheter to use with the infusion protocol.

[Chemical solution injection device for CT, etc.]
The present invention is not necessarily limited to a chemical solution injection device for angiography. For example, the present invention is also applicable to a chemical liquid injector as shown in FIGS.

  The chemical injection device D100 includes a two-tube injection head D110 that is rotatably held on an upper portion of a movable stand D111. In this injection head D110, as an example, a syringe is attached to each recess D120a via syringe cylinders S121 and S122 that hold the cylinder flange of the syringe and the vicinity thereof.

  The console D150 is an example, and is connected to the injection head D110 by a cable D102. The display unit D151 is a touch panel display. A plurality of physical buttons are arranged as the operation panel D159. For example, a home button (physical button) may be provided on the front of the console, and when the home button is pressed, a home screen on which a plurality of icons are arranged may be displayed on the screen. The hand unit D157 is wired to the console D150 and used on a work table or the like.

  Two syringes D200C and D200P may be detachably mounted in parallel on the injection head D110. In the following description, the syringes 2D00C and D200P may be simply referred to as “syringe D200” without being distinguished. The syringe D200 includes a hollow cylindrical cylinder member (also referred to as an outer cylinder) D221 and a piston member (also referred to as a plunger member) D222 that is slidably inserted into the cylinder member D221. As syringe D200, the thing for CT and for MRI can be used, for example. The pressure resistance performance may be 1.0 MPa or more, 1.5 MPa or more, for example. The cylinder member D221 may have a cylinder flange D221a formed at the base end portion thereof and a conduit portion 2D21b formed at the tip end portion thereof. By pushing the piston member D222 into the cylinder member D221, the chemical solution in the syringe is pushed out through the conduit portion D221b.

  It is preferable that at least a portion of the cylinder member D221 in which the chemical solution (liquid) is stored has a light-transmitting property, that is, is transparent or translucent so that the remaining amount of the chemical solution inside can be visually recognized. A scale capable of displaying the remaining amount of the chemical solution may be attached to the outer peripheral surface of the cylinder member. The maximum capacity of the cylinder member (in other words, the maximum capacity of the syringe) is not particularly limited, and is appropriately determined depending on the type and application of the stored chemical solution, but in contrast medium injection, there are many of about 50 ml to 200 ml. However, it is not limited to this, and it may be about 10 ml, 20 ml to 500 ml. Although the outer diameter of the cylinder member 221 depends on the capacity, it may be, for example, φ20 mm or more, φ30 mm or more, φ35 mm or more, φ45 mm or more. The length of the cylinder member 221 (from the proximal flange portion to the protruding portion at the distal end) may be 100 mm or greater, 150 mm or greater, 170 mm or greater, 200 mm or greater.

  The material of the gasket portion at the tip of the piston member D222 is not particularly limited as long as it is an elastic material that slides in the axial direction within the cylinder member D221. In one example, the elastic material includes, for example, various rubber materials such as natural rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, butyl rubber, silicone rubber, fluorine rubber, acrylic rubber, polyurethane, polyester, and polyamide. Various thermoplastic elastomers such as may be used. One or a plurality of ring-shaped sealing members may be provided on the outer peripheral portion of the gasket portion. For example, an O-ring can be used as the seal member, but the seal member is not limited to this.

  One or more IC tags D225 may be attached to a part of the syringe D200 (particularly, a part of the cylinder member D221). Regarding the IC tag, a part or all of the matters described in the above description can be applied to this kind of chemical liquid injector.

(Injection head of FIG. 20)
As an example, the injection head D110 has a housing that extends long in the front-rear direction, and two concave portions D120a on which syringes D200C and D200P are respectively placed are formed on the top end side of the housing. May be. The recessed part D120a is a part that functions as a syringe holding part. The syringe D200 may be directly attached to the recess D120a, or may be attached via a predetermined syringe adapter.

  The syringe adapter (not shown) may hold syringes individually, or may hold two syringes together.

  The injection head D110 may have two systems of piston drive mechanisms 130. In addition, various sensors as described in the above description may be mounted. The ram member of the piston drive mechanism 130 may hold one or a pair of locking claws that hold the piston flange at the tip. A bellows-like cover that covers the ram member may be provided.

  When the IC tag D225 is attached to the syringe, the injection head D110 includes a reader / writer 145 that reads information from the IC tag D225 and / or writes information to the IC tag D225 as shown in FIG. You may have. The reader / writer 145 may be provided in the recess D120a in which the syringe D200 is mounted. Note that the reader / writer 145 may have only a function of reading information of the IC tag D225.

(Various changes)
As mentioned above, although this invention was demonstrated with reference to some forms, naturally, unless the content conflicts, the technical matter disclosed by this specification can be combined suitably. Further, the present invention is not limited to the above contents, and various modifications can be made.

(P1) Data related to injection conditions may be read from the card medium, which is an information storage medium, into the chemical injection device. Various products can be used as the information storage medium. Data relating to the injection conditions can be downloaded online stored in an external database server. Such data may be GUI data for realizing a time / volume priority injection condition setting method and / or time / volume numerical data corresponding to the examination site.
(P2) By determining the type of contrast medium in the chemical syringe to be mounted, it is possible to eliminate the operation of inputting the type of contrast medium and reduce the work burden.

The chemical liquid injector and the system including the same are not limited to the above contents, and various modifications can be made as follows, for example:
(P3) An IC tag such as a syringe may include information on whether or not to heat the syringe.
(P4) At least a part of information read from the IC tag such as a syringe is printed using a printer or the like. Alternatively, data including at least a part of information read from an IC tag such as a syringe and at least chemical injection history data is printed using a printer or the like.
(P5) Information on whether or not the used syringe has been discarded is managed by a predetermined management server in the system.
(P6) With the function of the controller unit of the chemical liquid injector, the estimated value of the chemical liquid pressure during injection may be calculated using both the load cell and the motor current.
(P7) On the injection protocol setting screen, a predetermined help button is displayed on the screen, and when this button is pressed, help text on operation and display on the screen, a help image, a help guidance as sound, or a combination thereof Is displayed so that the control unit of the chemical injection device is configured.
(P8) The units of various numerical data displayed on the screen can be changed as appropriate. For example, the pressure may be switchable between at least two of “Kg / cm ² ”, “psi”, and “MPa”.
(P9) Display the contrast agent name (product name, etc.) on a part of the console screen. The computer of the chemical injection device has such a function.
(P10) A part of the screen of the console displays a status such as whether the console is connected to another device or connected and linked. The computer of the chemical injection device has such a function.

(P11) In the case of a method in which a chemical solution is sucked into an empty syringe, the chemical solution injection device may be configured as follows:
-With the syringe set on the injection head and the suction tube connected to a chemical bottle or the like, when a predetermined button is pressed, the gasket (piston member, plunger) moves forward to release air. Here, the predetermined button may be an autofill button as a specific example.
-The chemical solution is then aspirated.
As this step, first, the chemical solution is aspirated halfway (ie, only a part of the target amount is drawn, not the whole amount).
-Next, the air bleeding operation is performed again.
-After that, the suction of the chemical solution is continued until the target amount is reached. This suction may be the same as the initial suction speed or may be faster. Thereafter, the preparation is completed by advancing the piston member of the syringe by a small amount.

(P12) It is good also as a chemical | medical solution injection | pouring apparatus by which the inclination sensor is incorporated in the injection | pouring head. In this case, the control unit performs some or all of the following processes:
-It is determined whether or not the injection head is in a substantially vertical state (in other words, the front of the head on which the syringe is mounted is directed vertically upward).
-When the injection head is in a substantially vertical state, the autofill operation is allowed to be performed. Otherwise, autofill operation is prohibited.
Determine if the injection head is in a horizontal position or a position where the front is relatively low.
-In these postures, the liquid injection operation is allowed. Otherwise, the injection operation is prohibited.

(P13) As an operation for releasing air from the extension tube, the piston drive mechanism on the A syringe (contrast medium) side is operated, and then the piston drive mechanism on the B syringe (saline) side is operated. Also good. Alternatively, the piston drive mechanism on the A syringe (contrast medium) side and the piston drive mechanism on the B syringe (physiological saline) side may be operated simultaneously. A function called “auto purge” may be provided as an air bleeding operation.

(P14) The injection head and the console may be connected by a cable, but may be connected via a wireless communication unit or the like. In this case, the communication unit may be externally attached to the injection head or may be built in. Similarly, the communication unit may be externally attached to the console or may be built in.
(P15) A chemical liquid injector capable of controlling a predetermined operation of the chemical liquid injector from outside the examination room using a wired or wireless remote controller. In this case, the wireless system may be a system using infrared rays, or a wireless LAN, Wi-Fi (registered trademark), Bluetooth (registered trademark), ZigBee (registered trademark), or the like. Good.
(P16) The controlled operation may be any operation including, for example, power on / off of the apparatus. As another example, the start and / or stop of any operation of the injection head may be controlled with a remote controller.
(P17) A chemical injection device in which a control unit (for example, one having a single button or a plurality of buttons and / or a display) having a miniaturized console is arranged in the vicinity of the injection head. Such a control unit may be held on a movable stand together with the injection head in one example. Or, for example, such a control unit may be held on a ceiling-suspended arm together with an injection head.

  Note that the various components (devices, apparatuses, means, units, units, and the like) referred to in this specification do not have to be individually independent, and a plurality of components may be formed as a single member. Good. One component may be formed of a plurality of members. Some components may be part of other components. A part of a certain component and a part of another component may overlap.

  Here, in the present invention, the components in the control unit (computer unit, control circuit, processor unit) need only be formed so as to realize their functions, and even those realized by hardware are realized by software. Any of these may be used. For example, a certain component can be realized as dedicated hardware that exhibits a predetermined function, a processing device in which the predetermined function is realized by a computer program, a combination thereof, or the like.

  Various network systems for interconnecting devices can be used, for example, LAN (Local Area Network), WAN (Wide Area Network), CAN (Campus Area Network), WWW (World Wide Web), etc., or Any combination thereof may be used.

This application discloses the following invention (note that the reference numerals in parentheses do not limit the present invention in any way):
1. A method for controlling a chemical liquid injector that operates a piston drive mechanism to push out a chemical liquid in a syringe according to a predetermined injection condition, wherein the chemical liquid is at least a contrast agent,
(A1) Input from an operator regarding (i) information on the injection amount of a contrast medium to be injected in that phase and (ii) information on injection time in that phase for setting injection conditions in a predetermined phase A step of accepting,
(A2) creating an injection condition based on the input injection amount and injection time information;
(A3) starting chemical injection according to the injection conditions;
(A4) determining whether or not the injection speed of the contrast medium has reached a predetermined reference value during the liquid injection;
(A5) When the injection speed reaches the predetermined reference value, (i) determining the remaining amount of contrast medium to be injected and (ii) the remaining time until the injection completion time that is initially set;
(A6) calculating a new injection rate for finishing pushing out the contrast agent remaining amount from the syringe within the remaining time based on the contrast agent remaining amount and the remaining time;
(A7) Thereafter, the step of continuing the chemical solution injection according to the new injection rate;
A control method for a chemical injection device having

2. In the step (a4), the control method for the chemical liquid injector described above, wherein an output parameter of an actuator of the piston drive mechanism is detected.

3. The said piston drive mechanism has a motor as an actuator, Comprising: In the said (a4) step, the rotational speed of the said motor is detected as said output parameter, The control method of the said chemical | medical solution injection apparatus described above.

4). The method for controlling a chemical liquid injector according to the above, wherein the new injection speed reset in step (a6) is constant.

5. The control method for a chemical injection device according to the above, wherein the new injection speed reset in step (a6) has a plurality of phases having different speeds.

6). The control of the chemical injection device according to the above, wherein the new injection rate reset in the step (a6) includes at least one of a pattern that increases over time, a pattern that decreases, and a combination thereof. Method.

7). further,
(A8) having a step of determining whether or not the new injection rate reset in the step (a5) exceeds a predetermined rate limit;
A method for controlling the chemical liquid injector described above.

8). The predetermined speed limit is set to a value such that the pressure of the chemical liquid when the chemical liquid is injected at that speed does not exceed a predetermined upper limit value,
A method for controlling the chemical liquid injector described above.

9. further,
(A9) It has a step of displaying the chemical solution injection speed on the display in real time during the injection of the chemical solution.
A method for controlling the chemical liquid injector described above.

10. A piston drive mechanism (130) for extruding the chemical in the syringe according to predetermined injection conditions;
A control unit (153) electrically connected to the piston drive mechanism;
A chemical injection device comprising:
The drug solution is at least a contrast agent;
The control unit (153, 144)
(A1) Input from an operator regarding (i) information on the injection amount of a contrast medium to be injected in that phase and (ii) information on injection time in that phase for setting injection conditions in a predetermined phase Accept
(A2) Create injection conditions based on the input injection volume and injection time information,
(A3) Start the chemical injection according to the injection conditions,
(A4) During the injection of the chemical solution, it is determined whether the injection speed of the contrast medium has reached a predetermined reference value,
(A5) When the injection speed reaches the predetermined reference value, (i) determine the remaining amount of contrast medium to be injected, and (ii) the remaining time until the injection completion time initially set,
(A6) Based on the contrast agent remaining amount and the remaining time, calculate a new injection speed for finishing pushing out the contrast agent remaining amount from the syringe within the remaining time;
(A7) After that, the chemical solution injection is continued according to the new injection rate.
A chemical injection device configured as described above.

11. The control unit is
The chemical injection device according to the above, configured to detect an output parameter of an actuator of the piston drive mechanism by the operation (a4).

12 The piston drive mechanism has a motor as an actuator,
The control unit is
The chemical injection device according to the above, configured to detect a rotation speed of the motor as the output parameter in the operation (a4).

13. The control unit is
The chemical solution injection device according to the above, which is configured to set a new injection speed as a constant speed in the operation (a6).

14 The control unit is
In the operation (a6), the chemical injection device described above is configured to set a new injection speed as having a plurality of phases having different speeds.

15. The control unit is
In the operation of (a6), the new injection rate is configured to include at least one of a pattern that increases with time, a pattern that decreases, and a combination thereof. The chemical injection device according to the description.

16. The control unit further comprises:
(A8) In the operation of (a6), it is determined whether or not the new injection speed exceeds a predetermined speed limit.
The above-described chemical liquid injection device configured as described above.

17. The predetermined speed limit is set to a value such that the pressure of the chemical liquid when the chemical liquid is injected at that speed does not exceed a predetermined upper limit value,
A method for controlling the chemical liquid injector described above.

18. The control unit further comprises:
(A9) During the injection of the chemical liquid, the chemical liquid injection speed is displayed on the display in real time.
The above-described chemical liquid injection device configured as described above.

100 Chemical Solution Injection Device 110 Injection Head (Injector Head)
130 Piston drive mechanism 144 Computer unit (control circuit, control unit)
145 Various sensors 147a Heater 147b Display 147c Input device 148 Power supply unit (main unit)
150 Console 151 Display 153 Computer unit (control circuit, control unit)
157a Hand switch 157b Operation button 157c Slot 157d Foot switch 200 Syringe 210 Cylinder member 211b Conduit portion 214 Locking protrusion 220 Piston member 240 Protective case 241 Body member 300 Imaging device 303 Computer unit (control circuit, control unit)
304 Imaging unit 305 Interpretation monitor 701 Human body images 701a to 701d Body segment icons 702a to 703b Imaging region icons 703a to 703c Blood vessel part icon 713 Pressure display window 713a Pressure display unit 713b Pressure limit display 715 Injection condition 715v Indicator 716a Syringe image 721 Display region 721a Standby button (also functions as icon and start button)
721b Human body image icon (during injection)
725 Remaining amount display unit 901 HIS
902 RIS
903 PACS
904 Viewer 905 Printer

Claims (17)

A method for controlling a chemical liquid injector that operates a piston drive mechanism to push out a chemical liquid in a syringe according to a predetermined injection condition, wherein the chemical liquid is at least a contrast agent,
(A1) Input from an operator regarding (i) information on the injection amount of a contrast medium to be injected in that phase and (ii) information on injection time in that phase for setting injection conditions in a predetermined phase A step of accepting,
(A2) creating an injection condition based on the input injection amount and injection time information;
(A3) starting to drive the piston of the syringe according to the injection conditions;
(A4) determining whether or not the injection speed of the contrast medium has reached a predetermined reference value during the liquid injection;
(A5) When the injection speed reaches the predetermined reference value, (i) determining the remaining amount of contrast agent to be injected and (ii) the remaining time until the initially set injection completion time;
(A6) calculating a new injection rate for finishing pushing out the contrast agent remaining amount from the syringe within the remaining time based on the contrast agent remaining amount and the remaining time;
(A7) and thereafter, continuing to drive the piston of the syringe according to the new injection speed;
(A8) a step of determining whether or not the new injection rate reset in step (a6) exceeds a predetermined rate limit;
Have a, is performed by the control unit of the liquid injector each step of (a8) from (a1), the control method of the liquid injector.   The method for controlling a chemical injection device according to claim 1, wherein in the step (a4), an output parameter of an actuator of the piston drive mechanism is detected.   The method of controlling a chemical injection device according to claim 2, wherein the piston drive mechanism includes a motor as an actuator, and in the step (a4), the rotation speed of the motor is detected as the output parameter.   The control method of the chemical | medical solution injection apparatus as described in any one of Claims 1-3 with which the new injection | pouring speed reset by the said (a6) step is constant.   The control method of the chemical | medical solution injection apparatus of Claim 4 with which the new injection | pouring speed reset at the said (a6) step has several phases from which speed | velocity mutually differs.   The new infusion rate reset in the step (a6) includes at least one of a pattern that increases over time, a pattern that decreases, and a combination thereof. The control method of the chemical injection device according to one item. The predetermined speed limit is set to a value such that the pressure of the chemical liquid when the chemical liquid is injected at that speed does not exceed a predetermined upper limit value,
The control method of the chemical injection device according to any one of claims 1 to 6. further,
(A9) It has a step of displaying the chemical solution injection speed on the display in real time during the injection of the chemical solution.
The control method of the chemical injection device according to any one of claims 1 to 7. A piston drive mechanism for extruding the chemical in the syringe according to predetermined injection conditions;
A control unit electrically connected to the piston drive mechanism;
A chemical injection device comprising:
The drug solution is at least a contrast agent;
The control unit is
(A1) Input from an operator regarding (i) information on the injection amount of a contrast medium to be injected in that phase and (ii) information on injection time in that phase for setting injection conditions in a predetermined phase Accept
(A2) Create injection conditions based on the input injection volume and injection time information,
(A3) Start the chemical injection according to the injection conditions,
(A4) During the injection of the chemical solution, it is determined whether the injection speed of the contrast medium has reached a predetermined reference value,
(A5) When the injection speed reaches the predetermined reference value, (i) determine the remaining amount of contrast medium to be injected, and (ii) the remaining time until the initially set injection completion time,
(A6) Based on the contrast agent remaining amount and the remaining time, calculate a new injection speed for finishing pushing out the contrast agent remaining amount from the syringe within the remaining time;
(A7) After that, it is configured to continue the chemical injection according to the new injection rate,
further,
(A8) It is determined whether or not the new injection rate calculated in the operation of (a6) exceeds a predetermined rate limit.
A chemical injection device configured as described above. The control unit is
The chemical injection device according to claim 9, configured to detect an output parameter of an actuator of the piston drive mechanism by the operation (a4). The piston drive mechanism has a motor as an actuator,
The control unit is
The chemical | medical solution injection device of Claim 10 comprised so that the rotational speed of the said motor may be detected as said output parameter by the operation | movement of said (a4). The control unit is
The chemical injection device according to any one of claims 9 to 11, wherein a new injection rate is set as a constant rate in the operation (a6). The control unit is
The chemical injection device according to claim 12, wherein the new injection speed is set to have a plurality of phases having different speeds in the operation (a6). The control unit is
In the operation (a6), the new injection rate is configured to include at least one of a rising pattern, a decreasing pattern, and a combination pattern thereof over time. Item 12. The chemical injection device according to any one of Items 9 to 11. The predetermined speed limit is set to a value such that the pressure of the chemical liquid when the chemical liquid is injected at that speed does not exceed a predetermined upper limit value,
The chemical | medical solution injection device as described in any one of Claims 9-14. The control unit further comprises:
(A9) During the injection of the chemical liquid, the chemical liquid injection speed is displayed on the display in real time.
The chemical injection device according to any one of claims 9 to 15, which is configured as described above. A control program for a chemical injection device that operates a piston drive mechanism to push out a chemical in a syringe according to predetermined injection conditions, wherein the chemical is at least a contrast agent,
In the control unit of the chemical injection device,
(A1) Input from an operator regarding (i) information on the injection amount of a contrast medium to be injected in that phase and (ii) information on injection time in that phase for setting injection conditions in a predetermined phase A step of accepting,
(A2) creating an injection condition based on the input injection amount and injection time information;
(A3) starting to drive the piston of the syringe according to the injection conditions;
(A4) determining whether or not the injection speed of the contrast medium has reached a predetermined reference value during the liquid injection;
(A5) When the injection speed reaches the predetermined reference value, (i) determining the remaining amount of contrast agent to be injected and (ii) the remaining time until the initially set injection completion time;
(A6) calculating a new injection rate for finishing pushing out the contrast agent remaining amount from the syringe within the remaining time based on the contrast agent remaining amount and the remaining time;
(A7) and thereafter, continuing to drive the piston of the syringe according to the new injection speed;
(A8) a step of determining whether or not the new injection rate reset in step (a6) exceeds a predetermined rate limit;
This is a control program for the chemical injection device.

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