JP6348167B2 - 治療剤の制御された送達のための注入システム - Google Patents
治療剤の制御された送達のための注入システム Download PDFInfo
- Publication number
- JP6348167B2 JP6348167B2 JP2016502100A JP2016502100A JP6348167B2 JP 6348167 B2 JP6348167 B2 JP 6348167B2 JP 2016502100 A JP2016502100 A JP 2016502100A JP 2016502100 A JP2016502100 A JP 2016502100A JP 6348167 B2 JP6348167 B2 JP 6348167B2
- Authority
- JP
- Japan
- Prior art keywords
- therapeutic agent
- patient
- flow rate
- reservoir
- agent solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims description 186
- 229940124597 therapeutic agent Drugs 0.000 title claims description 122
- 238000001802 infusion Methods 0.000 title description 24
- 229940079593 drug Drugs 0.000 claims description 63
- 239000012530 fluid Substances 0.000 claims description 46
- 238000001990 intravenous administration Methods 0.000 claims description 43
- 239000000376 reactant Substances 0.000 claims description 35
- 239000007789 gas Substances 0.000 claims description 34
- 239000007788 liquid Substances 0.000 claims description 30
- 239000000126 substance Substances 0.000 claims description 15
- 238000006243 chemical reaction Methods 0.000 claims description 14
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims description 14
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 12
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 12
- 239000002253 acid Substances 0.000 claims description 12
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 12
- 239000003550 marker Substances 0.000 claims description 11
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical group [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 8
- 102000004877 Insulin Human genes 0.000 claims description 7
- 108090001061 Insulin Proteins 0.000 claims description 7
- 239000000853 adhesive Substances 0.000 claims description 7
- 230000001070 adhesive effect Effects 0.000 claims description 7
- 229940125396 insulin Drugs 0.000 claims description 7
- 102000018997 Growth Hormone Human genes 0.000 claims description 6
- 108010051696 Growth Hormone Proteins 0.000 claims description 6
- 239000002246 antineoplastic agent Substances 0.000 claims description 6
- 239000001569 carbon dioxide Substances 0.000 claims description 6
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 6
- 229940044683 chemotherapy drug Drugs 0.000 claims description 6
- 239000002872 contrast media Substances 0.000 claims description 6
- 239000000122 growth hormone Substances 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 238000010669 acid-base reaction Methods 0.000 claims description 4
- 210000004204 blood vessel Anatomy 0.000 claims description 4
- 238000012423 maintenance Methods 0.000 claims description 4
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims description 4
- 235000017557 sodium bicarbonate Nutrition 0.000 claims description 4
- 238000007920 subcutaneous administration Methods 0.000 claims description 4
- 150000007513 acids Chemical class 0.000 claims description 3
- 239000000730 antalgic agent Substances 0.000 claims 2
- 239000003124 biologic agent Substances 0.000 claims 2
- 239000003193 general anesthetic agent Substances 0.000 claims 2
- 239000000243 solution Substances 0.000 description 70
- 238000000034 method Methods 0.000 description 32
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
- 210000003462 vein Anatomy 0.000 description 8
- 238000002347 injection Methods 0.000 description 7
- 239000007924 injection Substances 0.000 description 7
- 210000001519 tissue Anatomy 0.000 description 7
- 239000000463 material Substances 0.000 description 6
- 230000003444 anaesthetic effect Effects 0.000 description 5
- 230000036541 health Effects 0.000 description 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 230000000202 analgesic effect Effects 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 238000004364 calculation method Methods 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 239000012620 biological material Substances 0.000 description 3
- 238000012377 drug delivery Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000002706 hydrostatic effect Effects 0.000 description 3
- 210000002414 leg Anatomy 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 206010002091 Anaesthesia Diseases 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 230000037005 anaesthesia Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000002512 chemotherapy Methods 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000002980 postoperative effect Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 210000003491 skin Anatomy 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 230000037317 transdermal delivery Effects 0.000 description 2
- 239000012780 transparent material Substances 0.000 description 2
- 241000283690 Bos taurus Species 0.000 description 1
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- 241001631457 Cannula Species 0.000 description 1
- 206010007559 Cardiac failure congestive Diseases 0.000 description 1
- 208000000094 Chronic Pain Diseases 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 241000283086 Equidae Species 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 206010016803 Fluid overload Diseases 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 229920001612 Hydroxyethyl starch Polymers 0.000 description 1
- 206010069803 Injury associated with device Diseases 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 206010037423 Pulmonary oedema Diseases 0.000 description 1
- 239000008156 Ringer's lactate solution Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 239000010836 blood and blood product Substances 0.000 description 1
- 229940125691 blood product Drugs 0.000 description 1
- 230000004706 cardiovascular dysfunction Effects 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000002178 crystalline material Substances 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 238000002637 fluid replacement therapy Methods 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229940014259 gelatin Drugs 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 229940027278 hetastarch Drugs 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 238000002642 intravenous therapy Methods 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000005980 lung dysfunction Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000005399 mechanical ventilation Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012806 monitoring device Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000003182 parenteral nutrition solution Substances 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 208000001297 phlebitis Diseases 0.000 description 1
- 238000005293 physical law Methods 0.000 description 1
- 208000005333 pulmonary edema Diseases 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 201000002327 urinary tract obstruction Diseases 0.000 description 1
- 210000005166 vasculature Anatomy 0.000 description 1
- 230000024883 vasodilation Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/14586—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of a flexible diaphragm
- A61M5/14593—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of a flexible diaphragm the diaphragm being actuated by fluid pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags
- A61M5/1483—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags using flexible bags externally pressurised by fluid pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M2005/14204—Pressure infusion, e.g. using pumps with gas-producing electrochemical cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3379—Masses, volumes, levels of fluids in reservoirs, flow rates
- A61M2205/3389—Continuous level detection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3546—Range
- A61M2205/3561—Range local, e.g. within room or hospital
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3546—Range
- A61M2205/3569—Range sublocal, e.g. between console and disposable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
Landscapes
- Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Fluid Mechanics (AREA)
- Physics & Mathematics (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361779817P | 2013-03-13 | 2013-03-13 | |
| US61/779,817 | 2013-03-13 | ||
| PCT/US2014/026314 WO2014160319A1 (en) | 2013-03-13 | 2014-03-13 | Infusion systems for the controlled delivery of therapeutic agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018064479A Division JP2018134439A (ja) | 2013-03-13 | 2018-03-29 | 治療剤の制御された送達のための注入システム |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016512123A JP2016512123A (ja) | 2016-04-25 |
| JP2016512123A5 JP2016512123A5 (https=) | 2017-02-16 |
| JP6348167B2 true JP6348167B2 (ja) | 2018-06-27 |
Family
ID=51530801
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502100A Expired - Fee Related JP6348167B2 (ja) | 2013-03-13 | 2014-03-13 | 治療剤の制御された送達のための注入システム |
| JP2018064479A Pending JP2018134439A (ja) | 2013-03-13 | 2018-03-29 | 治療剤の制御された送達のための注入システム |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018064479A Pending JP2018134439A (ja) | 2013-03-13 | 2018-03-29 | 治療剤の制御された送達のための注入システム |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9597449B2 (https=) |
| EP (1) | EP2968739B1 (https=) |
| JP (2) | JP6348167B2 (https=) |
| CN (1) | CN105163774A (https=) |
| WO (1) | WO2014160319A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021025484A1 (ko) * | 2019-08-06 | 2021-02-11 | 아주대학교산학협력단 | 약액 주입을 위한 미세바늘 스탬프 기기 |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9597449B2 (en) * | 2013-03-13 | 2017-03-21 | Incube Labs, Llc | Infusion system for the controlled delivery of therapeutic agents |
| US10780258B2 (en) * | 2015-03-10 | 2020-09-22 | Life Warmer Inc. | Thermic infusion system |
| US10806858B2 (en) * | 2016-02-17 | 2020-10-20 | Zyno Medical, Llc | Automatic anesthesiology pump allowing improved anesthesiologist mobility |
| US10238798B2 (en) * | 2016-03-22 | 2019-03-26 | Novartis Ag | Pressurizable fluid supply apparatus |
| EP3573686A1 (en) | 2017-01-24 | 2019-12-04 | Sanofi-Aventis Deutschland GmbH | Medicament delivery device |
| US10106393B1 (en) | 2017-04-19 | 2018-10-23 | Winter Creek Designs | Beverage dispensing system |
| US11065385B2 (en) * | 2017-06-08 | 2021-07-20 | Edwards Lifesciences Corporation | Fluid bolus detection |
| AU2018302130B2 (en) * | 2017-07-18 | 2020-12-24 | Becton, Dickinson And Company | Administration system, delivery device, and notification device for communicating status of a medical device |
| CA3074810C (en) * | 2017-09-08 | 2022-07-12 | Eli Lilly And Company | System for controlling gas generation within a drug delivery device |
| US11707580B2 (en) | 2017-09-08 | 2023-07-25 | Life Warmer Inc. | Thermic infusion system dry tube detector |
| AU2019300452A1 (en) * | 2018-07-11 | 2021-01-07 | Debiotech S.A. | Drug delivery system |
| WO2020018533A1 (en) * | 2018-07-19 | 2020-01-23 | Flowonix Medical Incorporated | Implantable drug delivery device with infusate measuring capabilities |
| CN213156401U (zh) * | 2019-09-04 | 2021-05-11 | 巴德阿克塞斯系统股份有限公司 | 一种针引导系统 |
| KR102436621B1 (ko) * | 2019-12-17 | 2022-08-25 | 조선대학교산학협력단 | 수액 주입장치 |
| WO2021167993A1 (en) * | 2020-02-18 | 2021-08-26 | Rani Therapeutics, Llc | Injection of a therapeutic formulation into a wall of the gastrointestinal tract |
| CN116419770A (zh) * | 2020-10-21 | 2023-07-11 | 康迈德有限公司 | 药物递送系统 |
| US12268840B2 (en) | 2021-01-22 | 2025-04-08 | Proportion-Air, Inc | System for dispensing fluid |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3298367A (en) | 1964-01-10 | 1967-01-17 | Richard I Bergman | Apparatus for administering parenteral liquids |
| US3877428A (en) | 1973-04-30 | 1975-04-15 | Sorenson Research Co | Variable infusion control device |
| CA1125134A (en) | 1977-05-16 | 1982-06-08 | Albert F. Bujan | Apparatus for administering incompatible i.v. liquids |
| US4175558A (en) | 1977-07-15 | 1979-11-27 | Baxter Travenol Laboratories, Inc. | Apparatus for administering parenteral liquid in sequential units provided with a ball valve float |
| US4379453A (en) * | 1978-12-28 | 1983-04-12 | Baron Howard C | Infusion system with self-generating pressure assembly |
| US4684367A (en) | 1985-04-12 | 1987-08-04 | Meditec Research Associates | Ambulatory intravenous delivery system |
| US4735613A (en) | 1986-10-23 | 1988-04-05 | Biomedical Dynamics Corporation | Pressure infusion device |
| US5013303A (en) * | 1988-11-03 | 1991-05-07 | Yehuda Tamari | Constant pressure infusion device |
| US4969872A (en) | 1989-03-08 | 1990-11-13 | Alza Corporation | Intravenous system for delivering a beneficial agent with delivery rate control via permeable surface area variance |
| US5019055A (en) | 1989-12-22 | 1991-05-28 | Boyle Matthew O | Flow regulator and method |
| US5492534A (en) * | 1990-04-02 | 1996-02-20 | Pharmetrix Corporation | Controlled release portable pump |
| US5135498A (en) * | 1990-04-02 | 1992-08-04 | Kam Robert J | Controlled release infusion device |
| US5318540A (en) * | 1990-04-02 | 1994-06-07 | Pharmetrix Corporation | Controlled release infusion device |
| US5106374A (en) | 1990-05-08 | 1992-04-21 | Abbott Laboratories | Ambulatory infusion device |
| WO1993025269A1 (en) * | 1992-06-15 | 1993-12-23 | Abbott Laboratories | Ambulatory energized container system |
| US5738657A (en) * | 1992-06-15 | 1998-04-14 | Abbott Laboratories | Ambulatory energized container system |
| US5318515A (en) | 1992-08-17 | 1994-06-07 | Wilk Peter J | Intravenous flow regulator device and associated method |
| US5348539A (en) | 1993-06-29 | 1994-09-20 | Glenn Herskowitz | Infusion pump for use with prepackaged IV bags |
| US5398851A (en) * | 1993-08-06 | 1995-03-21 | River Medical, Inc. | Liquid delivery device |
| DK0711243T3 (da) * | 1993-08-06 | 2000-05-29 | Maxxim Med Inc | Væskeafgivelsesanordning |
| JPH0858897A (ja) * | 1994-08-12 | 1996-03-05 | Japan Storage Battery Co Ltd | 流体供給装置 |
| US5700245A (en) * | 1995-07-13 | 1997-12-23 | Winfield Medical | Apparatus for the generation of gas pressure for controlled fluid delivery |
| US5707499A (en) * | 1995-10-06 | 1998-01-13 | Ceramatec, Inc. | Storage-stable, fluid dispensing device using a hydrogen gas generator |
| US6280416B1 (en) | 1999-02-19 | 2001-08-28 | Minimed Inc. | Constant flow medication infusion pump |
| JP2003501156A (ja) * | 1999-06-08 | 2003-01-14 | メディカル リサーチ グループ インコーポレイテッド | 埋め込み可能な注入デバイスにおける化学反応を利用した液体の注入法およびその装置 |
| US6428505B1 (en) | 1999-11-19 | 2002-08-06 | Prismedical Corporation | In-line IV drug delivery pack with controllable dilution |
| IL138766A0 (en) * | 2000-09-28 | 2001-10-31 | Cyclo Science Ltd | Constant pressure apparatus for the administration of fluids intravenously |
| US6969373B2 (en) * | 2001-04-13 | 2005-11-29 | Tricardia, Llc | Syringe system |
| US6796955B2 (en) * | 2002-02-14 | 2004-09-28 | Chf Solutions, Inc. | Method to control blood and filtrate flowing through an extracorporeal device |
| IL154243A0 (en) * | 2003-02-02 | 2003-09-17 | Silex Projectors Ltd | Stable infusion device |
| MXPA06001373A (es) * | 2003-08-12 | 2006-05-15 | Becton Dickinson Co | Dispositivo de infusion similar a un parche. |
| EP2104525A4 (en) * | 2006-12-29 | 2010-12-29 | Amir Genosar | HYPODERMIC RESERVOIR AND APPARATUS FOR DRUG DELIVERY |
| US8257337B2 (en) | 2007-05-02 | 2012-09-04 | Carefusion 303, Inc. | Intravenous fluid container |
| EP2344221B1 (en) | 2008-09-22 | 2018-04-25 | Incube Labs, Llc | Diaphragm drug pump |
| US8579859B2 (en) | 2009-12-26 | 2013-11-12 | Board Of Regents, The University Of Texas System | Fluid balance monitoring system with fluid infusion pump for medical treatment |
| US20120267275A1 (en) | 2011-04-22 | 2012-10-25 | Gilmore Dovie D | Cases for concealing alternative nutrition and/or intravenous bags hanging from an IV stand pole |
| CN104066465A (zh) * | 2011-12-02 | 2014-09-24 | 赫基梅德有限公司 | 移动输液装置 |
| US9597449B2 (en) | 2013-03-13 | 2017-03-21 | Incube Labs, Llc | Infusion system for the controlled delivery of therapeutic agents |
-
2014
- 2014-03-13 US US14/208,520 patent/US9597449B2/en not_active Expired - Fee Related
- 2014-03-13 EP EP14774822.2A patent/EP2968739B1/en not_active Not-in-force
- 2014-03-13 CN CN201480024032.3A patent/CN105163774A/zh active Pending
- 2014-03-13 JP JP2016502100A patent/JP6348167B2/ja not_active Expired - Fee Related
- 2014-03-13 WO PCT/US2014/026314 patent/WO2014160319A1/en not_active Ceased
-
2017
- 2017-03-17 US US15/462,602 patent/US10549031B2/en not_active Expired - Fee Related
-
2018
- 2018-03-29 JP JP2018064479A patent/JP2018134439A/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021025484A1 (ko) * | 2019-08-06 | 2021-02-11 | 아주대학교산학협력단 | 약액 주입을 위한 미세바늘 스탬프 기기 |
| US12318565B2 (en) | 2019-08-06 | 2025-06-03 | Ajou University Industry-Academic Cooperation Foundation | Microneedle stamp device for injecting liquid medicine |
Also Published As
| Publication number | Publication date |
|---|---|
| US9597449B2 (en) | 2017-03-21 |
| EP2968739A1 (en) | 2016-01-20 |
| US20140276587A1 (en) | 2014-09-18 |
| CN105163774A (zh) | 2015-12-16 |
| EP2968739A4 (en) | 2017-01-11 |
| JP2018134439A (ja) | 2018-08-30 |
| US20170281858A1 (en) | 2017-10-05 |
| EP2968739B1 (en) | 2020-04-22 |
| US10549031B2 (en) | 2020-02-04 |
| WO2014160319A1 (en) | 2014-10-02 |
| JP2016512123A (ja) | 2016-04-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6348167B2 (ja) | 治療剤の制御された送達のための注入システム | |
| JP2020006222A (ja) | 経腸栄養とともに使用するための胃システム、装置及び方法 | |
| US6699218B2 (en) | Transcutaneous delivery means | |
| JP4604022B2 (ja) | 運搬促進デリバリー法による組織および腫瘍への液体の投与のための携帯用装置 | |
| EP1824536B1 (en) | Ventilated skin mountable device | |
| EP2620173A1 (en) | Intravenous infusion pump system | |
| US20040092865A1 (en) | Transcutaneous delivery means | |
| AU736215B2 (en) | Intravenous infusion system | |
| US8323244B2 (en) | Catheter malfunction determinations using physiologic pressure | |
| US20040260232A1 (en) | Precision fluid delivery system and method for surgical procedures | |
| EP1951358A1 (en) | Cell delivery catheters with distal tip high fidelity sensors | |
| ES2885002T3 (es) | Dispositivo fijado por vía dérmica para acceso intravenoso | |
| JP2016512123A5 (https=) | ||
| US20070016171A1 (en) | Implantable perfusion device | |
| US20210016058A1 (en) | Indwelling venous cannula | |
| US20160303315A1 (en) | Infusion needle unit and liquid infusion apparatus | |
| AU2010207762A1 (en) | Transcutaneous delivery means | |
| US20230390484A1 (en) | Implantable insulin pump | |
| JP2025514012A (ja) | 閉鎖システム可撓性血管アクセスデバイスセンサデプロイシステム | |
| Ausman | New Technologies | |
| Voss et al. | 83.1 Performance Criteria for Intravenous Infusion Devices | |
| Serum | 2013 AAHA/AAFP Fluid Therapy Guidelines for Dogs and Cats | |
| De Castro et al. | Technical data of equipment for spinal opioid therapy |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20170113 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20170113 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20171030 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20171031 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20180118 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180329 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20180502 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20180530 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6348167 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |