JP6296057B2 - Automatic blood return method in case of emergency such as a power failure that occurred during blood purification - Google Patents

Automatic blood return method in case of emergency such as a power failure that occurred during blood purification Download PDF

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JP6296057B2
JP6296057B2 JP2015522767A JP2015522767A JP6296057B2 JP 6296057 B2 JP6296057 B2 JP 6296057B2 JP 2015522767 A JP2015522767 A JP 2015522767A JP 2015522767 A JP2015522767 A JP 2015522767A JP 6296057 B2 JP6296057 B2 JP 6296057B2
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circuit
valve
dialysate
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JPWO2014199949A1 (en
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洋一 鴨下
洋一 鴨下
将太 中村
将太 中村
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3643—Priming, rinsing before or after use
    • A61M1/3644—Mode of operation
    • A61M1/3649—Mode of operation using dialysate as priming or rinsing liquid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3643—Priming, rinsing before or after use
    • A61M1/3644—Mode of operation
    • A61M1/3646—Expelling the residual body fluid after use, e.g. back to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3643—Priming, rinsing before or after use
    • A61M1/3644—Mode of operation
    • A61M1/365—Mode of operation through membranes, e.g. by inverted trans-membrane pressure [TMP]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated

Description

本発明は、血液浄化治療中に発生した、停電や透析供給システムの故障などの緊急時に、自動的に返血を行うことが出来るようにする方法に関する。   The present invention relates to a method for automatically returning blood in an emergency such as a power failure or a failure of a dialysis supply system that occurs during blood purification treatment.

従来、腎不全の患者や、術後の薬液注入によって水分過多症になった患者などの重篤な状態を改善するために、血液浄化装置を使用する血液透析や血液濾過が行われている。そして、血液浄化治療中に停電や透析液供給システムの故障が発生した場合には、血液ポンプや血液回路の開閉弁、透析液ラインの開閉弁が全て閉鎖されてしまうため、従来は、制御装置に内蔵されたバッテリーを使用して、血液回路およびプライミングラインの開閉弁の開閉、血液ポンプの作動を行い、血液回路内にプライミング液（一般に、生理食塩液）を導入し、回路内に残留した血液を患者の体内に戻していた（この操作を返血という）。   Conventionally, hemodialysis and blood filtration using a blood purification apparatus have been performed in order to improve a serious condition such as a patient with renal failure or a patient with hyperhydration due to postoperative surgical fluid injection. In the event of a power failure or a failure of the dialysate supply system during blood purification treatment, all of the on / off valves of the blood pump, blood circuit, and dialysate line are closed. Using the built-in battery, the open / close valve of the blood circuit and the priming line is opened and closed, the blood pump is operated, and priming fluid (generally, physiological saline) is introduced into the blood circuit and remains in the circuit. The blood was returned to the patient's body (this operation is called blood return).

しかしながら、上記の返血方法は、別途プライミングラインを設けて、プライミング容器からプライミング液を血液回路内に導入する操作を必要とするため、手間が係り、また、プライミング液を使用するためコスト的に不利なものであった。   However, the above blood return method requires an operation of providing a separate priming line and introducing the priming liquid from the priming container into the blood circuit, which is troublesome and uses the priming liquid. It was a disadvantage.

そこで、近年、停電などの緊急時に透析液回路の新鮮透析液を利用した返血が提案されている（特許文献１、特許文献２）。
特許文献１の発明は、密閉された透析液回路に、この密閉された透析液回路を外部に解放する解放手段が設けられ、この解放手段よりも下流に設けられた、透析液供給通路を流通する新鮮透析液を貯留する透析液の貯留容器と、補液ポンプ、血液ポンプ、解放手段を作動させる補助電源を備えた血液透析装置であり、緊急時には制御手段を補助電源返血モードにすることにより、解放手段および補液ポンプを作動させて、貯留容器に貯留されている新鮮な透析液を、補液通路を介して血液回路に送液するようになっている。従って、新鮮透析液を貯留するための貯留容器と、この貯留容器を血液回路内に送液するための解放手段が別途必要になるため、緊急時が発生しないときには、これら別途設けた手段が無駄になり不経済である。また、エアを血液回路内に引き込んでしまう虞があるため、必ずしも安全な返血を行いうるものとはいえない。Therefore, in recent years, blood return using a fresh dialysate in a dialysate circuit in an emergency such as a power failure has been proposed (Patent Document 1, Patent Document 2).
In the invention of Patent Document 1, a release means for releasing the sealed dialysate circuit to the outside is provided in the sealed dialysate circuit, and flows through the dialysate supply passage provided downstream of the release means. A hemodialyzer equipped with a dialysate storage container for storing fresh dialysate and an auxiliary power supply for operating a replacement fluid pump, blood pump, and release means. The release means and the replacement fluid pump are operated to supply fresh dialysate stored in the storage container to the blood circuit via the replacement fluid passage. Therefore, since a separate storage container for storing fresh dialysate and a release means for sending the storage container into the blood circuit are required, these separate means are wasted when an emergency does not occur. It is uneconomical. In addition, since there is a possibility that air may be drawn into the blood circuit, it cannot always be said that safe blood return can be performed.

また、特許文献２の発明は、透析液導入ラインに濾過フィルタを具備しており、血液回路内の血液を患者の体内に戻す返血時、濾過フィルタ内の透析液を血液回路に向かって供給させつつ血液ポンプを駆動させる制御手段を備えた血液浄化装置である。従って、濾過フィルタ内の透析液を血液回路に向かって供給させる手段（透析液供給ラインにエアを導入する手段と血液ポンプの組み合わせ、または、透析液供給ラインにエアを導入する手段と補液ポンプの組み合わせ）を別途必要としており、緊急時が発生しないときには、これら別途設けた手段が無駄になり不経済である。また、エアを血液回路内に引き込んでしまう虞があるため、必ずしも安全な返血を行いうるものとはいえない。また、プライミングラインを設けた構成、すなわち透析液供給ラインにエアを導入する手段と血液ポンプの組み合わせの場合には、動脈側血液回路の一部の血液を返血できるものではない（明細書の段落番号０７６、５〜６行参照）。   Further, the invention of Patent Document 2 includes a filtration filter in the dialysate introduction line, and supplies the dialysate in the filtration filter toward the blood circuit when returning blood in the blood circuit to the patient's body. And a blood purification device including a control means for driving the blood pump. Therefore, means for supplying dialysate in the filtration filter toward the blood circuit (a combination of means for introducing air into the dialysate supply line and a blood pump, or means for introducing air into the dialysate supply line and the replacement fluid pump) When an emergency does not occur, these separately provided means are wasted and uneconomical. In addition, since there is a possibility that air may be drawn into the blood circuit, it cannot always be said that safe blood return can be performed. In addition, in the case of a configuration in which a priming line is provided, that is, a combination of a means for introducing air into the dialysate supply line and a blood pump, a part of the blood in the arterial blood circuit cannot be returned (see the description of the specification). (See paragraph number 076, lines 5-6).

特開２０１２−５６７０号公報JP 2012-5670 A 特開２０１２−３４７８２号公報JP 2012-34782 A

本発明は、上記事情に鑑みてなされたもので、停電等緊急時に、制御装置のバッテリーを作動させて（但し、停電以外の緊急時には通常の電源も使用できることは勿論である）、血液ポンプを駆動して透析回路の新鮮透析液を利用した返血を行う方法を提供することを目的とする。   The present invention has been made in view of the above circumstances, and in the event of an emergency such as a power failure, the battery of the control device is operated (however, a normal power supply can be used in an emergency other than a power failure). An object of the present invention is to provide a method for driving and returning blood using fresh dialysate in a dialysis circuit.

本発明の自動返血方法は、
血液浄化器と、
患者から前記血液浄化器へ血液を送る動脈側血液回路および前記血液浄化器から患者へ血液を戻す静脈側血液回路からなる血液回路と、
動脈側血液回路に設けられた血液ポンプと、
該血液ポンプより上流側の動脈側血液回路に設けられた動脈側開閉弁と、
静脈側血液回路に設けられた静脈チャンバと、
該静脈チャンバより下流側の静脈側血液回路に設けられた静脈側開閉弁と、
新鮮透析液を前記血液浄化器に供給する透析液供給回路および前記血液浄化器を通過した使用済みの透析液を回収する透析液排出回路からなる透析液回路と、
前記血液ポンプ等の作動を制御する制御装置とを含んでおり、
該透析液回路が柔軟な膜で区画されたチャンバを有する密閉式除水制御方式のものであって、
前記チャンバは透析液供給回路の一部である新鮮透析液室と透析液排出回路の一部である使用済透析液室とからなりっており、
新鮮透析液室の入口には第一開閉弁が設けられるとともに出口には第二開閉弁が設けられ、
使用済透析液室の入口には第三開閉弁が設けられるとともに出口には第四開閉弁が設けられ、
前記血液ポンプと動脈側開閉弁の間にプライミングラインが設けられており、
該プライミングラインには第五開閉弁を有するとともに、
該プライミングラインと前記透析液供給回路とが前記第二開閉弁の下流で接続され、
前記透析液供給回路におけるプライミングライン接続部分と前記血液浄化器との間に第六開閉弁が設けられてなる血液浄化装置において、
前記制御装置に内蔵されたバッテリーを作動させて、血液ポンプを駆動して前記透析液回路の新鮮な透析液を利用した返血を行うことを特徴とする（但し、停電以外の、例えば透析液供給側の故障により透析液の供給が出来なくなった場合などには、通常の電源を使用できることは勿論である）。The automatic blood return method of the present invention comprises:
A blood purifier,
A blood circuit comprising an arterial blood circuit for sending blood from a patient to the blood purifier and a venous blood circuit for returning blood from the blood purifier to the patient;
A blood pump provided in the arterial blood circuit;
An arterial on-off valve provided in the arterial blood circuit upstream of the blood pump;
A venous chamber provided in the venous blood circuit;
A venous side on-off valve provided in a venous blood circuit downstream from the venous chamber;
A dialysate circuit comprising a dialysate supply circuit for supplying fresh dialysate to the blood purifier and a dialysate discharge circuit for collecting used dialysate that has passed through the blood purifier;
A control device for controlling the operation of the blood pump or the like,
The dialysate circuit is of a closed water removal control system having a chamber partitioned by a flexible membrane,
The chamber consists of a fresh dialysate chamber that is part of the dialysate supply circuit and a spent dialysate chamber that is part of the dialysate discharge circuit,
A first on-off valve is provided at the inlet of the fresh dialysate chamber and a second on-off valve is provided at the outlet,
A third on-off valve is provided at the inlet of the spent dialysate chamber and a fourth on-off valve is provided at the outlet.
A priming line is provided between the blood pump and the arterial valve;
The priming line has a fifth on-off valve,
The priming line and the dialysate supply circuit are connected downstream of the second on-off valve;
In the blood purification apparatus in which a sixth open / close valve is provided between the priming line connection portion in the dialysate supply circuit and the blood purifier,
A battery built in the control device is operated, and a blood pump is driven to return blood using fresh dialysate in the dialysate circuit (however, for example, dialysate other than a power failure, for example) Of course, when the dialysate cannot be supplied due to a failure on the supply side, a normal power supply can be used.

上記の返血方法には、第１の実施形態としての、血液浄化治療中に発生した停電等緊急時において、制御装置のバッテリーを作動させて、
（Ａ）前記第二開閉弁および前記第四開閉弁、前記第五開閉弁、前記静脈側開閉弁をそれぞれ開く工程、
（Ｂ）前記血液ポンプを正回転させて、前記新鮮透析液室内に残っている新鮮透析液を、前記透析液供給回路、前記プライミングラインを通して、前記プライミングラインとの接続点より下流の血液回路に導入し、該回路内の血液を患者に返血する工程、
（Ｃ）前記血液ポンプを止め、前記静脈側開閉弁を閉じる工程、
（Ｄ）前記血液ポンプを所定回数正回転させて、前記血液ポンプより下流側の血液回路に前記新鮮透析液室から所定量の新鮮透析液を圧入する工程、
（Ｅ）前記第五開閉弁を閉じ、前記動脈側開閉弁を開き、前記血液ポンプを所定回数逆回転させて、圧入工程で前記血液ポンプより下流側の血液回路に圧入された新鮮透析液を、プライミングラインとの接続部分より上流側の血液回路に流入させ、前記血液回路内の血液の一部を返血する工程、
（Ｆ）前記動脈側開閉弁を閉じ、前記第五開閉弁を開き、前記血液ポンプを所定回数正回転させて、前記血液ポンプより下流側の血液回路に、新鮮透析液室から所定量の新鮮透析液を圧入する工程、
（Ｇ）前記プライミングラインの開閉弁を閉じ、前記動脈側血液回路の開閉弁を開き、前記血液ポンプを所定回数逆回転させて、（Ｆ）の工程で血液ポンプより下流側の血液回路に圧入された新鮮透析液を、前記プライミングラインとの接続部分より上流側の血液回路に流入させ、前記血液回路内の血液の一部を返血する工程、とからなり
返血が完了するまで、（Ｆ）、（Ｇ）の工程を繰り返す、の各工程を含んでなる返血方法と、第２の実施形態としての、血液浄化治療中に発生した停電等緊急時において、制御装置のバッテリーを作動させて、前記第二開閉弁および前記第四開閉弁、前記第五開閉弁、前記静脈側開閉弁をそれぞれ開く工程、
前記血液ポンプを正回転させて、前記新鮮透析液室内に残っている新鮮透析液を前記透析液供給回路、前記プライミングラインを通して、前記プライミングラインとの接続点より下流の血液回路に導入し、前記血液回路内の血液を患者に返血する工程、
第五開閉弁および静脈側開閉弁を閉じ、第六開閉弁と、動脈側開閉弁を開いて、血液ポンプを逆回転させ、逆濾過により前記プライミングラインとの接続部分より上流側の血液回路内の血液を返血する工程、
の各工程を含んでなる返血方法がある。In the above blood return method, in an emergency such as a power failure that occurred during blood purification treatment as the first embodiment, the battery of the control device is operated,
(A) opening the second on-off valve and the fourth on-off valve, the fifth on-off valve, and the venous side on-off valve,
(B) The blood pump is rotated forward so that the fresh dialysate remaining in the fresh dialysate chamber passes through the dialysate supply circuit and the priming line to the blood circuit downstream from the connection point with the priming line. Introducing and returning blood in the circuit to the patient;
(C) stopping the blood pump and closing the vein-side on-off valve;
(D) rotating the blood pump a predetermined number of times and press-fitting a predetermined amount of fresh dialysate into the blood circuit downstream from the blood pump from the fresh dialysate chamber;
(E) The fifth on-off valve is closed, the arterial side on-off valve is opened, the blood pump is reversely rotated a predetermined number of times, and the fresh dialysate press-fitted into the blood circuit downstream from the blood pump in the press-fitting step , Flowing into the blood circuit upstream of the connection portion with the priming line, and returning a part of the blood in the blood circuit;
(F) The arterial side on-off valve is closed, the fifth on-off valve is opened, the blood pump is rotated forward a predetermined number of times, and a predetermined amount of fresh fresh dialysate chamber is fed into the blood circuit downstream from the blood pump. Press-fitting dialysate,
(G) Close the opening / closing valve of the priming line, open the opening / closing valve of the arterial blood circuit, reversely rotate the blood pump a predetermined number of times, and press-fit into the blood circuit downstream of the blood pump in the step (F) And the step of allowing the fresh dialysis solution to flow into the blood circuit upstream of the connection portion with the priming line and returning a part of the blood in the blood circuit until the blood return is completed ( F) The blood return method comprising the steps of (G) is repeated, and the battery of the control device is operated in the event of an emergency such as a power failure that occurred during blood purification treatment as the second embodiment. Letting the second on-off valve and the fourth on-off valve, the fifth on-off valve, and the vein side on-off valve open,
The blood pump is rotated forward, and fresh dialysate remaining in the fresh dialysate chamber is introduced into the blood circuit downstream from the connection point with the priming line through the dialysate supply circuit and the priming line, Returning the blood in the blood circuit to the patient,
Close the fifth on-off valve and the venous side on-off valve, open the sixth on-off valve and the arterial side on-off valve, reversely rotate the blood pump, and in the blood circuit upstream from the connection with the priming line by reverse filtration Returning the blood of
There is a blood return method comprising these steps.

第１の実施形態においては、先ず、プライミングラインとの接続部分より上流側の血液回路内の血液を返血した後で、プライミングラインとの接続点より下流の血液回路内の血液を返血するようにしても良い。また、第２の実施形態においては、逆濾過による返血を先にして、先ず、プライミングラインとの接続部分より上流側の血液回路内の血液を返血した後で、プライミングラインとの接続点より下流の血液回路内の血液を返血するようにしても良い。但し、これらの方法を採用する場合には、プライミングラインと血液回路の接続部分において発生する虞のある血栓が患者の体内に入ることが無い様、プライミングラインと血液回路の接続部分より上流側の血液回路に別途血栓除去手段を設ける必要がある。   In the first embodiment, first, the blood in the blood circuit upstream from the connection portion with the priming line is returned, and then the blood in the blood circuit downstream from the connection point with the priming line is returned. You may do it. In the second embodiment, blood return by reverse filtration is performed first, and then blood in the blood circuit upstream from the connection portion with the priming line is returned first, and then the connection point with the priming line. Blood in the downstream blood circuit may be returned. However, when these methods are adopted, a thrombus that may occur at the connection portion between the priming line and the blood circuit does not enter the patient's body, so that it is located upstream from the connection portion between the priming line and the blood circuit. It is necessary to provide a separate clot removal means in the blood circuit.

以上、一般的に本発明を記述したが、より一層の理解は、いくつかの特定の実施例を参照することによって得ることができる。これらの実施例は、本明細書に例示の目的のためにのみ提供されるものであり、他の旨が特定されない限り、限定的なものではない。   Although the present invention has been generally described above, a better understanding can be obtained by reference to certain specific embodiments. These examples are provided herein for illustrative purposes only and are not limiting unless otherwise specified.

本発明によれば、以下のような効果が期待できる。すなわち、従来、停電等の緊急時のために別途プライミングラインや補液ラインを設ける必要があり、このプライミングライン（補液ライン）から導入したプライミング液（補液）を使用して返血を行う必要があったが、本発明の返血方法では、別途プライミングラインや補液ラインを設ける必要がないので、返血に手間がかからず、また、コスト的にも有利である。また、プライミング液として生理食塩液を利用する必要もないので、コスト的に有利である。また、新鮮透析液の利用に際して、透析液供給回路にエアを導入する必要が無いので、血液回路にエアを引き込んでしまう虞が無いので安全である。   According to the present invention, the following effects can be expected. That is, conventionally, it has been necessary to provide a separate priming line or replacement fluid line for emergencies such as power outages, and it has been necessary to return blood using the priming fluid (supplement fluid) introduced from this priming line (replacement fluid line). However, in the blood return method of the present invention, it is not necessary to provide a separate priming line or replacement fluid line, so that the blood return does not take time and is advantageous in terms of cost. Further, there is no need to use a physiological saline solution as the priming solution, which is advantageous in terms of cost. In addition, when using fresh dialysate, there is no need to introduce air into the dialysate supply circuit, so there is no risk of drawing air into the blood circuit, which is safe.

本発明に使用する血液浄化装置の治療時の状態を示す概略説明図である。It is a schematic explanatory drawing which shows the state at the time of the treatment of the blood purification apparatus used for this invention. 本発明の第１および第２の実施形態における静脈側の返血を示す概略説明図である。It is a schematic explanatory drawing which shows the blood return on the venous side in the 1st and 2nd embodiment of this invention. 本発明の第１の実施形態における動脈側の返血準備を示す概略説明図である。It is an approximate account figure showing blood return preparation by the side of an artery in a 1st embodiment of the present invention. 本発明の第１の実施形態における動脈側の返血を示す概略説明図である。It is a schematic explanatory drawing which shows the blood return of the artery side in the 1st Embodiment of this invention. 本発明の第２の実施形態における動脈側の返血を示す概略説明図である。It is a schematic explanatory drawing which shows the blood return of the artery side in the 2nd Embodiment of this invention.

先ず、本発明に使用する血液浄化装置について図面に基づいて説明する。
図１には本発明に使用する血液浄化装置の治療時の状態を示す概略説明図が示されている。ここでは、便宜のため、チャンバ２の透析液を使用した治療について説明する。
血液浄化装置としては、密閉式除水制御方式のダブルチャンバ方式のものが例示されており、このものは、新鮮な透析液を貯留し透析液供給回路６１、６２を通して血液浄化器１に供給する新鮮透析液室５１１、５２１と、透析液ポンプ６３の駆動により、血液浄化器１から透析液排出回路６４、６５を通って流入する使用済透析液を貯留する使用済透析液室５１２、５２２からなり、これら２つの室が柔軟な膜で仕切られてなるイコライザーになっている。
治療に際しては、図１に示すように、動脈側血液回路２１の動脈側開閉弁Ｖ１、静脈側血液回路２２の開閉弁Ｖ２、プライミングライン４と透析液供給回路６２との接続部分４２と血液浄化器１の間の透析液供給回路６２に設けられた開閉弁Ｖ３、透析液調製装置（図示していない）からチャンバ５１の新鮮透析液室５１１に新鮮透析液を供給するライン８１に設けられた第一開閉弁Ｖ５、廃液回路７１の第四開閉弁Ｖ８、透析液供給回路６２の第二開閉弁Ｖ１０、透析液排出回路６５の第三開閉弁Ｖ１１は開かれ、プライミングライン４の開閉弁Ｖ４、透析液供給回路６１の第二開閉弁Ｖ６、透析液排出回路６４の第三開閉弁Ｖ７、透析液調製装置からチャンバ５２の新鮮透析液室５２１に新鮮透析液を供給するライン８２に設けられた第一開閉弁Ｖ９、廃液回路７２の第四開閉弁Ｖ１２は閉じられている。First, a blood purification apparatus used in the present invention will be described with reference to the drawings.
FIG. 1 is a schematic explanatory view showing a state of the blood purification apparatus used in the present invention during treatment. Here, for convenience, treatment using the dialysate in the chamber 2 will be described.
Examples of the blood purification apparatus include a double chamber system of a closed water removal control system, which stores fresh dialysate and supplies it to the blood purifier 1 through the dialysate supply circuits 61 and 62. From the fresh dialysate chambers 511 and 521 and the used dialysate chambers 512 and 522 storing the used dialysate flowing from the blood purifier 1 through the dialysate discharge circuits 64 and 65 by driving the dialysate pump 63. Thus, these two chambers are equalized by a flexible membrane.
In the treatment, as shown in FIG. 1, the arterial side on / off valve V1 of the arterial side blood circuit 21, the on / off valve V2 of the venous side blood circuit 22, the connection part 42 between the priming line 4 and the dialysate supply circuit 62, and blood purification. On-off valve V3 provided in the dialysate supply circuit 62 between the vessels 1, provided in a line 81 for supplying fresh dialysate from the dialysate preparation device (not shown) to the fresh dialysate chamber 511 of the chamber 51. The first on-off valve V5, the fourth on-off valve V8 of the waste liquid circuit 71, the second on-off valve V10 of the dialysate supply circuit 62, and the third on-off valve V11 of the dialysate discharge circuit 65 are opened, and the on-off valve V4 of the priming line 4 is opened. , A second on-off valve V6 of the dialysate supply circuit 61, a third on-off valve V7 of the dialysate discharge circuit 64, and a line 82 for supplying fresh dialysate from the dialysate preparation device to the fresh dialysate chamber 521 of the chamber 52. First Off valve V9, the fourth on-off valve V12 waste circuit 72 is closed.

患者から採取された血液は血液ポンプ３により動脈側血液回路２１を通って血液浄化器１に送られ、ここで浄化されて静脈側血液回路２２を通って患者に戻される一方、新鮮透析液は透析液ポンプ６３によりチャンバ５２の新鮮透析液室５２１から透析液供給回路６２を通って血液浄化器１に供給され、ここで血液ポンプ３により血液浄化器１に供給された血液を浄化し、使用済透析液は透析液排出回路６５を通って使用済透析液室５２２に貯留される。この時、チャンバ５１では、新鮮透析液室５２１にライン８１を通って透析液調整室から供給される新鮮な透析液が貯留される一方、使用済透析液室５１２に貯留されている使用済透析液は、ライン８１から供給される新鮮透析液と同量が排液回路７１を通って捨てられる。ここで、符号２３は静脈チャンバ、符号６１はチャンバ５１の透析液供給回路、符号６４はチャンバ５１の透析液排出回路、符号７２はチャンバ５２の使用済透析液を使用済透析液室５２２から捨てる廃液回路であり、符号８２はチャンバ５２の新鮮透析液室５２１に透析液調製装置からの新鮮透析液を供給するラインである。   The blood collected from the patient is sent to the blood purifier 1 through the arterial blood circuit 21 by the blood pump 3, where it is purified and returned to the patient through the venous blood circuit 22, while fresh dialysate is The blood is supplied from the fresh dialysate chamber 521 of the chamber 52 through the dialysate supply circuit 62 to the blood purifier 1 by the dialysate pump 63, where the blood supplied to the blood purifier 1 by the blood pump 3 is purified and used. The spent dialysate is stored in the spent dialysate chamber 522 through the dialysate discharge circuit 65. At this time, in the chamber 51, the fresh dialysate supplied from the dialysate adjustment chamber through the line 81 is stored in the fresh dialysate chamber 521, while the used dialysate stored in the used dialysate chamber 512 is stored. The same amount of fresh dialysate supplied from the line 81 is discarded through the drain circuit 71. Here, reference numeral 23 is a venous chamber, reference numeral 61 is a dialysate supply circuit for the chamber 51, reference numeral 64 is a dialysate discharge circuit for the chamber 51, and reference numeral 72 is a used dialysate solution for the chamber 52 that is discarded from the used dialysate chamber 522. Reference numeral 82 denotes a line for supplying fresh dialysate from the dialysate preparation device to the fresh dialysate chamber 521 of the chamber 52.

次に本発明の第１の実施形態について、停電が図１に示す状態で発生したものとして説明する。この時開放弁Ｖ１〜Ｖ１２は全て閉じている。
図２は本発明の第１の実施形態における静脈側の返血（正確にはプライミングラインとの接続部分より下流の血液回路内の返血）を示す概略説明図であり、図３は本発明の第１の実施形態における動脈側の返血準備を示す概略説明図で、図４は本発明の第１の実施形態における動脈側の返血（正確にはプライミングラインとの接続部分より上流の血液回路内の返血）を示す概略説明図である。
第１の実施形態では、先ず、血液浄化治療中に発生した停電時において、制御装置（図示していない）のバッテリーを作動させて、図２に示すように、静脈側開閉弁Ｖ２、動脈側開閉弁Ｖ４、第二開閉弁Ｖ６、Ｖ１０、第四開閉弁Ｖ８、Ｖ１２をそれぞれ開き、血液ポンプ３を正回転させると、第四開閉弁Ｖ８、Ｖ１２が開いているため、廃液回路７１、７２にエアが流入して、大気圧でチャンバ５１、５２の柔軟な膜を押すことができる。従って、この膜が新鮮透析液室５１１、５２１側に移動して、透析液回路のチャンバ５１、５２内に残っている新鮮透析液が、透析液供給回路６１（６２）、プライミングライン４を通して、このプライミングライン４との接続点４１より下流の血液回路に導入され、この血液回路内の血液が患者に返血される。次に、一旦血液ポンプ３を止め、次いで、図３に示すように、静脈側開閉弁Ｖ２を閉じ、血液ポンプ３を所定回数正回転させると、血液ポンプ３より下流側の血液回路に透析液回路のチャンバ５１、５２から所定量の新鮮透析液が圧入される。次に、図４に示すように、第五開閉弁Ｖ４を閉じ、動脈側開閉弁Ｖ１を開いて、血液ポンプ３を所定回数逆回転させると、前の工程で血液ポンプより下流側の血液回路に圧入された新鮮透析液が、プライミングライン４との接続部分４１より上流側の血液回路に導入され、この血液回路内の血液の一部が返血される。次に、動脈側開閉弁Ｖ１を閉じ、第五開閉弁Ｖ４を開いて、血液ポンプ３を所定回数正回転させて、この血液ポンプ３より下流側の血液回路に、透析液回路のチャンバ５１、５２から所定量の新鮮透析液を圧入する。次に、第五開閉弁Ｖ４を閉じ、動脈側開閉弁Ｖ１を開いて、血液ポンプ３を所定回数逆回転させ、プライミングライン４との接続部分４１より上流側の血液回路内の血液の一部を返血する。後は、返血が完了するまで、図３に示す、血液ポンプ３の正回転による新鮮透析液の圧入と、図４に示す、血液ポンプ３の逆回転による返血、を繰り返せばよい。Next, a first embodiment of the present invention will be described assuming that a power failure has occurred in the state shown in FIG. At this time, the release valves V1 to V12 are all closed.
FIG. 2 is a schematic explanatory view showing blood return on the venous side according to the first embodiment of the present invention (more precisely, blood return in the blood circuit downstream from the connection portion with the priming line), and FIG. 3 shows the present invention. FIG. 4 is a schematic explanatory view showing preparation for blood return on the artery side in the first embodiment of the present invention. FIG. 4 shows blood return on the artery side in the first embodiment of the present invention (exactly upstream of the connection portion with the priming line). It is a schematic explanatory view showing blood return in the blood circuit.
In the first embodiment, first, at the time of a power failure that occurs during blood purification treatment, a battery of a control device (not shown) is operated, and as shown in FIG. When the on-off valve V4, the second on-off valves V6, V10, the fourth on-off valves V8, V12 are opened and the blood pump 3 is rotated forward, the fourth on-off valves V8, V12 are open. Air can flow into the chamber and push the flexible membranes of the chambers 51 and 52 at atmospheric pressure. Therefore, the membrane moves to the fresh dialysate chambers 511 and 521, and the fresh dialysate remaining in the chambers 51 and 52 of the dialysate circuit passes through the dialysate supply circuit 61 (62) and the priming line 4, The blood is introduced into the blood circuit downstream from the connection point 41 with the priming line 4, and the blood in the blood circuit is returned to the patient. Next, once the blood pump 3 is stopped, and then, as shown in FIG. 3, when the vein-side on-off valve V2 is closed and the blood pump 3 is rotated forward a predetermined number of times, the dialysate is introduced into the blood circuit downstream from the blood pump 3. A predetermined amount of fresh dialysate is injected from the chambers 51 and 52 of the circuit. Next, as shown in FIG. 4, when the fifth on-off valve V4 is closed, the arterial side on-off valve V1 is opened, and the blood pump 3 is reversely rotated a predetermined number of times, the blood circuit downstream from the blood pump in the previous step The fresh dialysate press-fitted into the priming line 4 is introduced into the blood circuit upstream of the connection portion 41 with the priming line 4, and a part of the blood in the blood circuit is returned. Next, the artery side opening / closing valve V1 is closed, the fifth opening / closing valve V4 is opened, the blood pump 3 is rotated forward a predetermined number of times, and the blood circuit downstream of the blood pump 3 is connected to the chamber 51 of the dialysate circuit, A predetermined amount of fresh dialysate is injected from 52. Next, the fifth on-off valve V4 is closed, the arterial side on-off valve V1 is opened, the blood pump 3 is reversely rotated a predetermined number of times, and a part of the blood in the blood circuit upstream from the connection part 41 with the priming line 4 To return blood. Thereafter, until the blood return is completed, the press-fitting of fresh dialysate by forward rotation of the blood pump 3 shown in FIG. 3 and the blood return by reverse rotation of the blood pump 3 shown in FIG. 4 may be repeated.

次に、本発明の第２の実施形態について説明する（第１の実施形態と同様、図１の状態で停電が発生したとして説明する）。
図２は、第２の実施形態における静脈側の返血（正確にはプライミングラインとの接続部分より下流の血液回路内の返血）を示す概略説明図であり、図５は、第２の実施形態における動脈側の返血（正確にはプライミングラインとの接続部分より上流の血液回路内の返血）を示す概略説明図である。
ここで、図２に示す返血については、第１の実施形態における返血と同様なので説明を省略する。
静脈側の返血が終了すると、次に、図５に示すように、静脈側開閉弁Ｖ２、第五開閉弁Ｖ４を閉じ、動脈側開閉弁Ｖ１、第六開閉弁Ｖ３を開いて、血液ポンプ３を逆回転させると、新鮮透析液は逆濾過により、透析液室５１１、５２１から透析液供給回路６１（６２）を通って、血液浄化器１に供給され、血液浄化器１より上流側の血液回路内に導入されて、プライミングライン４との接続部分４１より上流側の血液回路内の血液が患者に返血される。Next, a second embodiment of the present invention will be described (as in the first embodiment, description will be made assuming that a power failure has occurred in the state of FIG. 1).
FIG. 2 is a schematic explanatory diagram showing blood return on the venous side in the second embodiment (more precisely, blood return in the blood circuit downstream from the connection portion with the priming line), and FIG. It is a schematic explanatory drawing which shows the blood return on the artery side in the embodiment (more precisely, blood return in the blood circuit upstream from the connection portion with the priming line).
Here, since the blood return shown in FIG. 2 is the same as the blood return in the first embodiment, the description thereof is omitted.
When the blood return on the venous side is completed, as shown in FIG. 5, the venous side on-off valve V2 and the fifth on-off valve V4 are closed, the arterial side on-off valve V1 and the sixth on-off valve V3 are opened, and the blood pump 3 is reversely rotated, the fresh dialysate is supplied by reverse filtration from the dialysate chambers 511 and 521 to the blood purifier 1 through the dialysate supply circuit 61 (62) and on the upstream side of the blood purifier 1. The blood is introduced into the blood circuit, and the blood in the blood circuit upstream of the connection portion 41 with the priming line 4 is returned to the patient.

本発明の返血方法では、別途プライミングラインや補液ラインを設ける必要がないので、返血に手間がかからず、また、コスト的にも有利である。また、プライミング液として生理食塩液を利用する必要もないので、コスト的に有利である。また、新鮮透析液の利用に際して、透析液供給回路にエアを導入する必要が無いので、血液回路にエアを引き込んでしまう虞が無いので安全である。   In the blood return method of the present invention, it is not necessary to provide a separate priming line or a replacement fluid line, so that it does not take time for blood return and is advantageous in terms of cost. Further, there is no need to use a physiological saline solution as the priming solution, which is advantageous in terms of cost. In addition, when using fresh dialysate, there is no need to introduce air into the dialysate supply circuit, so there is no risk of drawing air into the blood circuit, which is safe.

１ 血液浄化器
２ 血液回路
２１ 動脈側血液回路
２２ 静脈側血液回路
２３ 静脈チャンバ
３ 血液ポンプ
４ プライミングライン
４１ プライミングラインと動脈側血液回路の接続点
４２ プライミングラインと透析液供給回路の接続点
５１、５２ 透析液回路のチャンバ
５１１、５２１ 新鮮透析液室
５１２、５２２ 使用済透析液室
６１、６２ 透析液供給回路
６３ 透析液ポンプ
６４、６５ 透析液排出回路
７１、７２ 廃液回路
８１、８２ 透析液調製装置から新鮮透析液室に新鮮透析液を供給するライン
Ｖ１ 動脈側開閉弁
Ｖ２ 静脈側開閉弁
Ｖ３ 第六開閉弁
Ｖ４ 第五開閉弁
Ｖ５、Ｖ９ 第一開閉弁
Ｖ６、Ｖ１０ 第二開閉弁
Ｖ７、Ｖ１１ 第三開閉弁
Ｖ８、Ｖ１２ 第四開閉弁DESCRIPTION OF SYMBOLS 1 Blood purifier 2 Blood circuit 21 Arterial blood circuit 22 Venous blood circuit 23 Venous chamber 3 Blood pump 4 Priming line 41 Connection point of priming line and arterial blood circuit 42 Connection point 51 of priming line and dialysate supply circuit 51 52 Dialysate circuit chamber 511, 521 Fresh dialysate chamber 512, 522 Used dialysate chamber 61, 62 Dialysate supply circuit 63 Dialysate pump 64, 65 Dialysate discharge circuit 71, 72 Waste fluid circuit 81, 82 Dialysate preparation Line for supplying fresh dialysate from the device to the fresh dialysate chamber V1 Arterial side on-off valve V2 Venous side on-off valve V3 Sixth on-off valve V4 Fifth on-off valve V5, V9 First on-off valve V6, V10 Second on-off valve V7, V11 3rd on-off valve V8, V12 4th on-off valve

Claims (2)

血液浄化器と、患者から前記血液浄化器へ血液を送る動脈側血液回路および前記血液浄化器から患者へ血液を戻す静脈側血液回路からなる血液回路と、動脈側血液回路に設けられた血液ポンプと、該血液ポンプより上流側の動脈側血液回路に設けられた動脈側開閉弁と、静脈側血液回路に設けられた静脈チャンバと、該静脈チャンバより下流側の静脈側血液回路に設けられた静脈側開閉弁と、新鮮透析液を前記血液浄化器に供給する透析液供給回路および前記血液浄化器を通過した使用済みの透析液を回収する透析液排出回路からなる透析液回路と、前記血液ポンプ等の作動を制御する制御装置とを含んでおり、該透析液回路が柔軟な膜で区画されたチャンバを有する密閉式除水制御方式のものであって、前記チャンバは透析液供給回路の一部である新鮮透析液室と透析液排出回路の一部である使用済透析液室とからなっており、新鮮透析液室の入口には第一開閉弁が設けられるとともに出口には第二開閉弁が設けられ、使用済透析液室の入口には第三開閉弁が設けられるとともに出口には第四開閉弁が設けられ、前記血液ポンプと動脈側開閉弁の間にプライミングラインが設けられており、該プライミングラインには第五開閉弁を有するとともに、該プライミングラインと前記透析液供給回路とが前記第二開閉弁の下流で接続され、前記透析液供給回路におけるプライミングライン接続部分と前記血液浄化器との間に第六開閉弁が設けられてなる血液浄化装置において、前記制御装置に内蔵されたバッテリーを作動させて、血液ポンプを駆動して前記透析液回路の新鮮な透析液を利用した返血を行うことを特徴とする、血液浄化治療中に発生した停電等緊急時における自動返血方法であって、
（Ａ）前記バッテリーにより前記第二開閉弁および前記第四開閉弁、前記第五開閉弁、前記静脈側開閉弁をそれぞれ開く工程、
（Ｂ）前記バッテリーにより前記血液ポンプを正回転させて、前記新鮮透析液室内に残っている新鮮透析液を、前記透析液供給回路、前記プライミングラインを通して、前記プライミングラインとの接続点より下流の血液回路に導入し、該回路内の血液を患者に返血する工程、
（Ｃ）前記バッテリーにより前記血液ポンプを止め、前記静脈側開閉弁を閉じる工程、
（Ｄ）前記バッテリーにより前記血液ポンプを所定回数正回転させて、前記血液ポンプより下流側の血液回路に前記新鮮透析液室から所定量の新鮮透析液を圧入する工程、
（Ｅ）前記バッテリーにより前記第五開閉弁を閉じ、前記動脈側開閉弁を開き、前記血液ポンプを所定回数逆回転させて、圧入工程で前記血液ポンプより下流側の血液回路に圧入された新鮮透析液を、プライミングラインとの接続部分より上流側の血液回路に流入させ、前記血液回路内の血液の一部を返血する工程、
（Ｆ）前記バッテリーにより前記動脈側開閉弁を閉じ、前記第五開閉弁を開き、前記血液ポンプを所定回数正回転させて、前記血液ポンプより下流側の血液回路に、新鮮透析液室から所定量の新鮮透析液を圧入する工程、
（Ｇ）前記バッテリーにより前記プライミングラインの開閉弁を閉じ、バッテリーにより前記動脈側血液回路の開閉弁を開き、バッテリーにより前記血液ポンプを所定回数逆回転させて、（Ｆ）の工程で血液ポンプより下流側の血液回路に圧入された新鮮透析液を、前記プライミングラインとの接続部分より上流側の血液回路に流入させ、前記血液回路内の血液の一部を返血する工程、の各工程とからなり返血が完了するまで、（Ｆ）、（Ｇ）の工程を繰り返すことを含んでなる自動返血方法。 A blood pump comprising a blood purifier, an arterial blood circuit for sending blood from a patient to the blood purifier, a venous blood circuit for returning blood from the blood purifier to the patient, and a blood pump provided in the arterial blood circuit And an arterial on-off valve provided in the arterial blood circuit upstream from the blood pump, a venous chamber provided in the venous blood circuit, and a venous blood circuit downstream from the venous chamber. A dialysis fluid circuit comprising a venous side opening / closing valve, a dialysis fluid supply circuit that supplies fresh dialysis fluid to the blood purifier, and a dialysate drain circuit that collects used dialysate that has passed through the blood purifier, and the blood A control device for controlling the operation of a pump or the like, wherein the dialysate circuit has a sealed water removal control system having a chamber partitioned by a flexible membrane, the chamber being a dialysate supply circuit one A fresh dialysate chamber and a spent dialysate chamber which is a part of the dialysate discharge circuit. The fresh dialysate chamber has a first on-off valve at the inlet and a second on-off valve at the outlet. A third open / close valve is provided at the entrance of the used dialysate chamber and a fourth open / close valve is provided at the exit, and a priming line is provided between the blood pump and the arterial open / close valve. The priming line has a fifth on-off valve, and the priming line and the dialysate supply circuit are connected downstream of the second on-off valve, and the priming line connection portion in the dialysate supply circuit and the blood purification device In the blood purification apparatus provided with a sixth open / close valve between the container and the battery built in the control device, the blood pump is driven to supply fresh dialysate in the dialysate circuit. And performing use the blood return, an automated blood return method in a power failure emergencies that occur during blood purification treatment,
(A) opening the second on-off valve, the fourth on-off valve, the fifth on-off valve, and the vein side on-off valve by the battery,
(B) The blood pump is rotated forward by the battery, and the fresh dialysate remaining in the fresh dialysate chamber passes through the dialysate supply circuit and the priming line and is downstream from the connection point with the priming line. Introducing into the blood circuit and returning the blood in the circuit to the patient;
(C) stopping the blood pump with the battery and closing the vein-side on-off valve;
(D) a step of rotating the blood pump forward a predetermined number of times by the battery and press-fitting a predetermined amount of fresh dialysate into the blood circuit downstream from the blood pump from the fresh dialysate chamber;
(E) The fifth on-off valve is closed by the battery, the arterial side on-off valve is opened, the blood pump is reversely rotated a predetermined number of times, and the freshly press-fitted into the blood circuit downstream from the blood pump in the press-fitting step Allowing the dialysate to flow into the blood circuit upstream of the connection with the priming line and returning a portion of the blood in the blood circuit;
(F) The battery closes the arterial on-off valve, opens the fifth on-off valve, rotates the blood pump forward a predetermined number of times, and enters the blood circuit downstream of the blood pump from the fresh dialysate chamber. A process of press-fitting a fixed amount of fresh dialysate,
(G) The on-off valve of the priming line is closed by the battery, the on-off valve of the arterial blood circuit is opened by the battery, and the blood pump is reversely rotated a predetermined number of times by the battery. Each step of flowing fresh dialysate press-fitted into the blood circuit on the downstream side into the blood circuit upstream from the connection portion with the priming line and returning a part of the blood in the blood circuit; An automatic blood return method comprising repeating steps (F) and (G) until blood return is completed. 血液浄化器と、患者から前記血液浄化器へ血液を送る動脈側血液回路および前記血液浄化器から患者へ血液を戻す静脈側血液回路からなる血液回路と、動脈側血液回路に設けられた血液ポンプと、該血液ポンプより上流側の動脈側血液回路に設けられた動脈側開閉弁と、静脈側血液回路に設けられた静脈チャンバと、該静脈チャンバより下流側の静脈側血液回路に設けられた静脈側開閉弁と、新鮮透析液を前記血液浄化器に供給する透析液供給回路および前記血液浄化器を通過した使用済みの透析液を回収する透析液排出回路からなる透析液回路と、前記血液ポンプ等の作動を制御する制御装置とを含んでおり、該透析液回路が柔軟な膜で区画されたチャンバを有する密閉式除水制御方式のものであって、前記チャンバは透析液供給回路の一部である新鮮透析液室と透析液排出回路の一部である使用済透析液室とからなっており、新鮮透析液室の入口には第一開閉弁が設けられるとともに出口には第二開閉弁が設けられ、使用済透析液室の入口には第三開閉弁が設けられるとともに出口には第四開閉弁が設けられ、前記血液ポンプと動脈側開閉弁の間にプライミングラインが設けられており、該プライミングラインには第五開閉弁を有するとともに、該プライミングラインと前記透析液供給回路とが前記第二開閉弁の下流で接続され、前記透析液供給回路におけるプライミングライン接続部分と前記血液浄化器との間に第六開閉弁が設けられてなる血液浄化装置において、前記制御装置に内蔵されたバッテリーを作動させて、血液ポンプを駆動して前記透析液回路の新鮮な透析液を利用した返血を行うことを特徴とする、血液浄化治療中に発生した停電等緊急時における自動返血方法であって、A blood pump comprising a blood purifier, an arterial blood circuit for sending blood from a patient to the blood purifier, a venous blood circuit for returning blood from the blood purifier to the patient, and a blood pump provided in the arterial blood circuit And an arterial on-off valve provided in the arterial blood circuit upstream from the blood pump, a venous chamber provided in the venous blood circuit, and a venous blood circuit downstream from the venous chamber. A dialysis fluid circuit comprising a venous side opening / closing valve, a dialysis fluid supply circuit that supplies fresh dialysis fluid to the blood purifier, and a dialysate drain circuit that collects used dialysate that has passed through the blood purifier, and the blood A control device for controlling the operation of a pump or the like, wherein the dialysate circuit has a sealed water removal control system having a chamber partitioned by a flexible membrane, the chamber being a dialysate supply circuit one A fresh dialysate chamber and a spent dialysate chamber which is a part of the dialysate discharge circuit. The fresh dialysate chamber has a first on-off valve at the inlet and a second on-off valve at the outlet. A third open / close valve is provided at the entrance of the used dialysate chamber and a fourth open / close valve is provided at the exit, and a priming line is provided between the blood pump and the arterial open / close valve. The priming line has a fifth on-off valve, and the priming line and the dialysate supply circuit are connected downstream of the second on-off valve, and the priming line connection portion in the dialysate supply circuit and the blood purification device In the blood purification apparatus provided with a sixth open / close valve between the container and the battery built in the control device, the blood pump is driven to supply fresh dialysate in the dialysate circuit. And performing use the blood return, an automated blood return method in a power failure emergencies that occur during blood purification treatment,
前記バッテリーにより前記第二開閉弁および前記第四開閉弁、前記第五開閉弁、前記静脈側開閉弁をそれぞれ開く工程、Opening the second on-off valve and the fourth on-off valve, the fifth on-off valve, and the vein side on-off valve by the battery,
前記バッテリーにより前記血液ポンプを正回転させて、前記新鮮透析液室内に残っている新鮮透析液を前記透析液供給回路、前記プライミングラインを通して、前記プライミングラインとの接続点より下流の血液回路に導入し、前記血液回路内の血液を患者に返血する工程、The blood pump is rotated forward by the battery, and the fresh dialysate remaining in the fresh dialysate chamber is introduced into the blood circuit downstream from the connection point with the priming line through the dialysate supply circuit and the priming line. And returning the blood in the blood circuit to the patient,
前記バッテリーにより第五開閉弁および静脈側開閉弁を閉じ、第六開閉弁と、動脈側開閉弁を開いて、血液ポンプを逆回転させ、逆濾過により前記プライミングラインとの接続部分より上流側の血液回路内の血液を返血する工程、The battery closes the fifth on-off valve and the venous side on-off valve, opens the sixth on-off valve and the arterial side on-off valve, reversely rotates the blood pump, and is upstream of the connection with the priming line by reverse filtration. Returning blood in the blood circuit;
の各工程を含んでなる自動返血方法。An automatic blood return method comprising each of the steps.
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