JP6285972B2 - Acy−1の虚血/再灌流、移植片機能発現遅延及び移植片バイアビリティーのマーカーとしての使用及びその方法 - Google Patents
Acy−1の虚血/再灌流、移植片機能発現遅延及び移植片バイアビリティーのマーカーとしての使用及びその方法 Download PDFInfo
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- JP6285972B2 JP6285972B2 JP2015562318A JP2015562318A JP6285972B2 JP 6285972 B2 JP6285972 B2 JP 6285972B2 JP 2015562318 A JP2015562318 A JP 2015562318A JP 2015562318 A JP2015562318 A JP 2015562318A JP 6285972 B2 JP6285972 B2 JP 6285972B2
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- C—CHEMISTRY; METALLURGY
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- G01N2333/98—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
- G01N2800/245—Transplantation related diseases, e.g. graft versus host disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7019—Ischaemia
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1304460.7A GB201304460D0 (en) | 2013-03-13 | 2013-03-13 | Biomarker |
| GB1304460.7 | 2013-03-13 | ||
| PCT/GB2014/050768 WO2014140595A1 (en) | 2013-03-13 | 2014-03-13 | Use of acy-1 as a marker of ischaemia/reperfusion, delayed graft function and graft viability as well as method thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016512325A JP2016512325A (ja) | 2016-04-25 |
| JP2016512325A5 JP2016512325A5 (cg-RX-API-DMAC10.html) | 2017-04-20 |
| JP6285972B2 true JP6285972B2 (ja) | 2018-02-28 |
Family
ID=48189800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562318A Expired - Fee Related JP6285972B2 (ja) | 2013-03-13 | 2014-03-13 | Acy−1の虚血/再灌流、移植片機能発現遅延及び移植片バイアビリティーのマーカーとしての使用及びその方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10184941B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2972384B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP6285972B2 (cg-RX-API-DMAC10.html) |
| CN (1) | CN105051543A (cg-RX-API-DMAC10.html) |
| GB (1) | GB201304460D0 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2014140595A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3789765A1 (en) * | 2019-09-09 | 2021-03-10 | ETH Zürich | A method for evaluating damage of solid tissue |
| CN115109767B (zh) * | 2020-02-12 | 2023-07-25 | 青岛农业大学 | 一种氨基酰化酶-1提高细菌抗聚乙二醇能力的方法和用途 |
| US20220241028A1 (en) * | 2021-01-22 | 2022-08-04 | Ethicon Llc | Prediction of blood perfusion difficulties based on biomarker monitoring |
| WO2024076485A1 (en) * | 2022-10-06 | 2024-04-11 | Natera, Inc. | Nucleic acid analysis of perfusion or flush fluids |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2892171B2 (ja) * | 1991-03-22 | 1999-05-17 | 寳酒造株式会社 | ポリペプチド |
| US7262017B2 (en) | 2001-09-14 | 2007-08-28 | Torrey Pines Institute For Molecular Studies | Diagnostic markers for ischemia |
| US8741557B2 (en) * | 2003-02-14 | 2014-06-03 | Beth Israel Deaconess Medical Center, Inc. | Predicting graft rejection |
| JPWO2008032868A1 (ja) | 2006-09-15 | 2010-01-28 | 株式会社島津製作所 | 腎癌の腫瘍マーカー及び腎癌の罹患の識別方法 |
| EP2131200A1 (en) | 2008-06-04 | 2009-12-09 | BRAHMS Aktiengesellschaft | A marker for graft failure and mortality |
| FR2933773B1 (fr) * | 2008-07-10 | 2013-02-15 | Biomerieux Sa | Procede de dosage de la proteine disulfide isomerase pour le diagnostic in vitro du cancer colorectal |
| US9938579B2 (en) | 2009-01-15 | 2018-04-10 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarker panel for diagnosis and prediction of graft rejection |
| ES2356217B1 (es) | 2009-08-04 | 2012-02-13 | Universidad De Salamanca | Método para la detección de daño renal. |
-
2013
- 2013-03-13 GB GBGB1304460.7A patent/GB201304460D0/en not_active Ceased
-
2014
- 2014-03-13 JP JP2015562318A patent/JP6285972B2/ja not_active Expired - Fee Related
- 2014-03-13 CN CN201480015268.0A patent/CN105051543A/zh active Pending
- 2014-03-13 EP EP14713890.3A patent/EP2972384B1/en active Active
- 2014-03-13 WO PCT/GB2014/050768 patent/WO2014140595A1/en not_active Ceased
- 2014-03-13 US US14/775,219 patent/US10184941B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| GB201304460D0 (en) | 2013-04-24 |
| WO2014140595A1 (en) | 2014-09-18 |
| EP2972384A1 (en) | 2016-01-20 |
| CN105051543A (zh) | 2015-11-11 |
| US20160033507A1 (en) | 2016-02-04 |
| US10184941B2 (en) | 2019-01-22 |
| JP2016512325A (ja) | 2016-04-25 |
| EP2972384B1 (en) | 2017-07-26 |
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