JP6252800B2 - 平衡化装置、透析器械、体外回路、及び流量測定セルを用いた流体の平衡化方法 - Google Patents
平衡化装置、透析器械、体外回路、及び流量測定セルを用いた流体の平衡化方法 Download PDFInfo
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- JP6252800B2 JP6252800B2 JP2015509332A JP2015509332A JP6252800B2 JP 6252800 B2 JP6252800 B2 JP 6252800B2 JP 2015509332 A JP2015509332 A JP 2015509332A JP 2015509332 A JP2015509332 A JP 2015509332A JP 6252800 B2 JP6252800 B2 JP 6252800B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1601—Control or regulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1635—Constructional aspects thereof with volume chamber balancing devices between used and fresh dialysis fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1647—Constructional aspects thereof with flow rate measurement of the dialysis fluid, upstream and downstream of the dialyser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3663—Flow rate transducers; Flow integrators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F7/00—Volume-flow measuring devices with two or more measuring ranges; Compound meters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3334—Measuring or controlling the flow rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3337—Controlling, regulating pressure or flow by means of a valve by-passing a pump
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3379—Masses, volumes, levels of fluids in reservoirs, flow rates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/0318—Processes
- Y10T137/0324—With control of flow by a condition or characteristic of a fluid
- Y10T137/0368—By speed of fluid
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/2496—Self-proportioning or correlating systems
- Y10T137/2703—Flow rate responsive
Description
S1:第1の流路中の流量と第2の流路中の流量の流量差を測定するステップ、
S2:追加の流路中の流量を設定するための装置に関する所定の条件を満たすための操作可能な変数として測定流量差を用いるステップ、及び
S3:この装置を用いて追加の流路中の流量を設定し、この流量を定め、そしてこの流量を用いて流体平衡のための尺度を導き出すステップを有する。
Claims (19)
- 第1の流路(FW1)中の流量と第2の流路(FW2)中の流量との流体平衡を算定する平衡化装置(100,101,200,201,301,303)であって、
前記第1の流路(FW1)中の流量と前記第2の流路(FW2)中の流量との流量差を測定する流量差測定ユニット(D)を有し、
前記2つの流路(FW1,FW2)のうちの一方から分かれていて前記2つの流路のうちの一方から追加の流路(W)中に流体を送り込む枝路を有し、
前記追加の流路中の流量を設定する装置(P1,P11,P12)を有し、該装置は、前記測定された流量差が所定の条件を満たすように制御可能であり、
前記追加の流路中の前記流量を前記流体平衡の尺度として定める装置(K)を有する、平衡化装置(100,101,200,201,301,303)。 - 前記追加の流路(W)中の前記流量を設定する前記装置(P11,P12)は、前記追加の流路中の前記流量を定める前記装置(P11,P12)を含む、請求項1記載の平衡化装置(100,101,200,201,301,303)。
- 前記追加の流路中の前記流量を設定する前記装置(P1,P11,P12)は、調節可能なポンプ(P11,P12)として設計されている、請求項1又は2記載の平衡化装置(100,101,200,201,301,303)。
- 前記流量差測定ユニット(D)は、前記第1の流路中の流れの別個の測定又は前記第2の流路中の流れの別個の測定を行わないで前記第1の流路中の流れと前記第2の流路中の流れの流量差を直接測定する流量差センサとして設計されている、請求項1〜3のいずれか1項に記載の平衡化装置(100,101,200,201,301,303)。
- 前記流量差センサは、前記第1の流路(FW1)中に設けられた第1の流量測定セル(K1)及び前記第2の流路(FW2)中に設けられた第2の流量測定セル(K2)を有し、前記流れは、前記第1の流量測定セル内の流れと逆行する関係をなして前記第2の流量測定セル中を通る、請求項4記載の平衡化装置(100,101,200,201,301,303)。
- 前記流量差測定ユニットは、前記第1の流路中の流量を測定する第1の流量センサ(K1)及び前記第2の流路中の流量を測定する第2の流量センサ(K2)を含む、請求項1〜3のいずれか1項に記載の平衡化装置(100,101,200,201,301,303)。
- 前記第1及び/又は前記第2の流量センサは、体積流量センサ又は質量流量センサとして設計された流量測定セルである、請求項6記載の平衡化装置(100,101,200,201,301,303)。
- 前記追加の流路は、遮断弁を有する、請求項1〜7のいずれか1項に記載の平衡化装置(100,101,200,201,301,303)。
- 前記所定の条件は、前記流量差がほぼゼロである場合に満たされる、請求項1〜8のいずれか1項に記載の平衡化装置(100,101,200,201,301,303)。
- 前記追加の流路中の流量を定める前記装置は、前記流量を集める容器を有し、前記流量は、重量測定又は充填レベル検出によって決定できる、請求項1〜9のいずれか1項に記載の平衡化装置(100,101)。
- 前記容器は、袋である、請求項10記載の平衡化装置。
- 前記流量差センサ(D)から見て上流側又は下流側に位置した前記追加の流路(W)は、上流側又は下流側で前記2つの流路のうちの一方中に戻って開口し、それにより、前記2つの流路のうちの一方に対して並列の流路を形成している、請求項1〜8のいずれか1項に記載の平衡化装置(200,201,301)。
- 前記流量差は、流量又は流れの体積として定められる、請求項1〜12のいずれか1項に記載の平衡化装置。
- 部分的に又は全体として使い捨て物品として又は使い捨て物品の一部として具体化される、請求項1〜13のいずれか1項に記載の平衡化装置。
- 前記流量差は、体積差として、流量差の積分値として、又は前記第1の流路中の流量の積分値と前記第2の流路中の流量の積分値との差として測定可能である、請求項1〜14のいずれか1項に記載の平衡化装置。
- 透析液を平衡化するための、請求項1〜15のいずれか1項に記載の平衡化装置を有する透析器械。
- 血液路及び透析液路を有する体外血液処置ユニットであって、前記透析液路中の透析液を平衡化するための、請求項1〜15のいずれか1項に記載の平衡化装置を有する、体外血液処置ユニット。
- 請求項1〜14のいずれか1項に記載の平衡化装置の作動方法であって、
前記平衡化装置が、前記第1の流路中の流量と前記第2の流路中の流量との流量差を測定するステップ(S1,S62)と、
前記平衡化装置が、前記測定された流量差を前記追加の流路中の流量を設定する前記装置のための操作可能な変数として用いるステップ(S2,S63)と、
前記平衡化装置が、前記追加の流路中の前記流量を前記流体平衡の尺度として定めるステップ(S3)と、を含む、
ことを特徴とする方法。 - 前記所定の条件は、前記流量差がほぼゼロである場合に満たされる、請求項18記載の方法。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261642631P | 2012-05-04 | 2012-05-04 | |
DE201210009043 DE102012009043A1 (de) | 2012-05-04 | 2012-05-04 | Bilanziervorrichtung, Dialysegerät, extrakorporaler Kreislauf und Verfahren zur Bilanzierung von Flüssigkeiten mit einer Flussmesszelle |
DE102012009043.9 | 2012-05-04 | ||
US61/642,631 | 2012-05-04 | ||
PCT/EP2013/001294 WO2013164089A1 (de) | 2012-05-04 | 2013-05-02 | Bilanziervorrichtung dialysegerät, extrakorporaler kreislauf und verfahren zur bilanzierung von flüssigkeiten mit einer flussmesszelle |
Publications (2)
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JP2015515869A JP2015515869A (ja) | 2015-06-04 |
JP6252800B2 true JP6252800B2 (ja) | 2017-12-27 |
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JP2015509332A Expired - Fee Related JP6252800B2 (ja) | 2012-05-04 | 2013-05-02 | 平衡化装置、透析器械、体外回路、及び流量測定セルを用いた流体の平衡化方法 |
Country Status (6)
Country | Link |
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US (2) | US20130292312A1 (ja) |
EP (1) | EP2844314B1 (ja) |
JP (1) | JP6252800B2 (ja) |
CN (1) | CN104363934B (ja) |
DE (1) | DE102012009043A1 (ja) |
WO (1) | WO2013164089A1 (ja) |
Families Citing this family (11)
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DE102013001587A1 (de) * | 2013-01-30 | 2014-07-31 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung und Verfahren zur Regelung einer Behandlungsvorrichtung |
DE102013002395A1 (de) * | 2013-02-13 | 2014-08-14 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung und Verfahren zur Regelung einer Behandlungsvorrichtung |
DE102013019356A1 (de) * | 2013-11-19 | 2015-06-03 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung und Verfahren zum Bilanzieren von Flüssigkeiten für eine extrakorporale Blutbehandlungsvorrichtung |
US10980929B2 (en) | 2014-09-12 | 2021-04-20 | Diality Inc. | Hemodialysis system with ultrafiltration controller |
US10016550B2 (en) | 2014-09-12 | 2018-07-10 | Easydial, Inc. | Portable hemodialysis assembly with ammonia sensor |
DE102015001406B3 (de) * | 2015-02-04 | 2016-07-14 | Fresenius Medical Care Deutschland Gmbh | Kassettenmodul für einen Differenzflussmesser und Differenzflussmesser |
DE102015104431A1 (de) | 2015-03-24 | 2016-09-29 | Fresenius Medical Care Deutschland Gmbh | Bilanzierungsverfahren und temperaturstörungsunabhängige Bilanzierungseinrichtung |
DE102015010316A1 (de) * | 2015-08-06 | 2017-02-09 | Fresenius Medical Care Deutschland Gmbh | Portable Ultrafiltrationseinheit und Vorrichtung zur Versorgung der Ultrafiltrationseinheit mit Dialysierflüssigkeit |
DE102015015636A1 (de) * | 2015-12-02 | 2017-06-08 | Fresenius Medical Deutschland Gmbh | Verfahren zum Testen der Rigidität eines Disposables |
CN105727382B (zh) * | 2016-01-28 | 2017-12-22 | 龚德华 | 一种两断路装置的连续式crrt机器容量平衡装置 |
DE102017125962A1 (de) | 2017-11-07 | 2019-05-09 | B. Braun Avitum Ag | Vorrichtung zur extrakorporalen Blutbehandlung mit gravimetrischer Bilanzierung und Möglichkeit zur Ultrafiltration |
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DE3313421C2 (de) * | 1983-04-13 | 1985-08-08 | Fresenius AG, 6380 Bad Homburg | Einrichtung zum Regeln der Ultrafiltrationsrate bei Vorrichtungen zum extrakorporalen Reinigen von Blut |
DE3720665A1 (de) * | 1987-06-23 | 1989-01-05 | Schael Wilfried | Vorrichtung zur haemodialyse und haemofiltration |
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DE19523505A1 (de) * | 1994-07-13 | 1996-01-18 | Fresenius Ag | Hämo(dia)filtrationsvorrichtung mit Filtratflußsteuerung |
DE19700466A1 (de) * | 1997-01-09 | 1998-07-16 | Polaschegg Hans Dietrich Dr | Einrichtung und Verfahren zur Hämodiafiltration |
FR2767478B1 (fr) * | 1997-08-21 | 1999-10-01 | Hospal Ind | Dispositif et procede pour regler la concentration du sodium dans un liquide de dialyse en vue d'une prescription |
SE510286C2 (sv) * | 1997-09-22 | 1999-05-10 | Gambro Med Tech Ab | Förfarande och anordning för övervakning av infusionspump i en hemo- eller hemodiafiltreringsmaskin |
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DE19928407C1 (de) * | 1999-06-22 | 2000-10-26 | Fresenius Medical Care De Gmbh | Verfahren zur Bestimmung der Leistungsfähigkeit eines Dialysators einer Dialysevorrichtung und Dialysevorrichtung zur Durchführung des Verfahrens |
DE10051943B4 (de) * | 2000-10-19 | 2015-01-15 | Fresenius Medical Care Deutschland Gmbh | Verfahren und Vorrichtung zur Pulswellenlaufzeitbestimmung und extrakorporale Blutbehandlungseinrichtung mit einer solchen Vorrichtung |
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US8753515B2 (en) * | 2009-12-05 | 2014-06-17 | Home Dialysis Plus, Ltd. | Dialysis system with ultrafiltration control |
-
2012
- 2012-05-04 DE DE201210009043 patent/DE102012009043A1/de not_active Withdrawn
-
2013
- 2013-05-02 EP EP13720795.7A patent/EP2844314B1/de active Active
- 2013-05-02 CN CN201380023226.7A patent/CN104363934B/zh active Active
- 2013-05-02 JP JP2015509332A patent/JP6252800B2/ja not_active Expired - Fee Related
- 2013-05-02 WO PCT/EP2013/001294 patent/WO2013164089A1/de active Application Filing
- 2013-05-06 US US13/887,464 patent/US20130292312A1/en not_active Abandoned
-
2017
- 2017-01-05 US US15/398,963 patent/US20170112990A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
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CN104363934A (zh) | 2015-02-18 |
US20170112990A1 (en) | 2017-04-27 |
US20130292312A1 (en) | 2013-11-07 |
EP2844314B1 (de) | 2018-02-21 |
JP2015515869A (ja) | 2015-06-04 |
EP2844314A1 (de) | 2015-03-11 |
WO2013164089A1 (de) | 2013-11-07 |
DE102012009043A1 (de) | 2013-11-07 |
CN104363934B (zh) | 2017-09-29 |
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