JP6238085B2 - 粉末薬剤用吸入装置 - Google Patents
粉末薬剤用吸入装置 Download PDFInfo
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- JP6238085B2 JP6238085B2 JP2014552568A JP2014552568A JP6238085B2 JP 6238085 B2 JP6238085 B2 JP 6238085B2 JP 2014552568 A JP2014552568 A JP 2014552568A JP 2014552568 A JP2014552568 A JP 2014552568A JP 6238085 B2 JP6238085 B2 JP 6238085B2
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- 239000000843 powder Substances 0.000 title claims description 85
- 239000003814 drug Substances 0.000 title claims description 31
- 230000007723 transport mechanism Effects 0.000 claims description 22
- 230000000994 depressogenic effect Effects 0.000 claims description 19
- 230000007246 mechanism Effects 0.000 claims description 14
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- WSVLPVUVIUVCRA-KPKNDVKVSA-N Alpha-lactose monohydrate Chemical compound O.O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O WSVLPVUVIUVCRA-KPKNDVKVSA-N 0.000 description 1
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- 238000006073 displacement reaction Methods 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 229940112141 dry powder inhaler Drugs 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
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- 230000000007 visual effect Effects 0.000 description 1
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0066—Inhalators with dosage or measuring devices with means for varying the dose size
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
- A61M15/0016—Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A61M15/0025—Mouthpieces therefor with caps
- A61M15/0026—Hinged caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/007—Mechanical counters
- A61M15/0071—Mechanical counters having a display or indicator
- A61M15/0073—Mechanical counters having a display or indicator on a ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0081—Locking means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0095—Preventing manual activation in absence of inhalation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0096—Hindering inhalation before activation of the dispenser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
- A61M2205/584—Means for facilitating use, e.g. by people with impaired vision by visual feedback having a color code
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
- F04C2270/00—Control; Monitoring or safety arrangements
- F04C2270/04—Force
- F04C2270/042—Force radial
- F04C2270/0421—Controlled or regulated
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Description
2 リザーバ
3 カートリッジ
3a カートリッジ本体
4 蓋
5 投与キー
6 投与レバー
7 ロックレバー
8 投与スライド
9 空気ダクト
10 マウスピース
11 マウスピースキャップ
12、13 シェル
14 カバー
15 弁室
16 サイクロン
16a 粉末溝
17 投与キーばね
18 投与スライド通路
19 投与キャビティ
20 開口部
21 開口部
22 フラップ弁
22a フラップ
22b フラップ弁のシャフト
22c フラップ弁の第1の脚部
22d フラップ弁の第2の脚部
22e フラップ弁の第3の脚部
23 締結フック
24 切欠き部分
25 投与レバーばね
26 舌部材
27 アクチュエータブレード
28 はす縁
29 ラッチ
30 機械的ストッパ
31 フラップ弁レバー
32 フラップ弁のばね
33 作動要素
34 カウンタースライド
35 カウンターリング
36 表示窓
37 歯部
38 ロックラチェット
39 ブロックアーム
40 ばね脚部
41 ノッチ
42 舌部
43 爪
44 摺動チャネル
45 凹部
46 投与レバーの先端
47 ラッチリブ
48 吸入制御窓
49 タブ
50 鉤状突出部
51 傾斜面
52 シールリブ
53 偏向面
53’ 偏向面
54 支持面
55 作動リブ
Claims (9)
- 吸入に起因する空気流によって患者に摂取される粉末薬剤用の吸入装置であって、少なくとも1つの粉末リザーバ(2)と、該リザーバ(2)からの粉末用量を繰り返し計量するための計量手段と、粉末用量を収容するための充填位置から前記粉末用量を粉末チャネルに放出するための排出位置へ、前記計量手段を移動させるための搬送機構と、前記患者による手動操作のための少なくとも1つの作動装置とを備え、前記作動装置は、動作時に単回粉末用量が計量されているように、前記搬送機構に動作可能に接続され、前記作動装置が、前記患者によって押されたときに前記搬送機構に作用する投与キー(5)を備えている吸入装置において、
前記投与キー(5)は、前記搬送機構の投与レバー(6)に一時的に係合する可撓性のアームまたは可撓性の脚部を有し、前記可撓性のアームまたは可撓性の脚部は、第1の非偏向位置で前記投与レバー(6)から係合解除され、第2の偏向位置で前記投与レバー(6)と係合されるものであり、前記投与キー(5)が押し下げられた状態に保持されるとしても、計量サイクルが完了し、前記搬送機構および/または前記計量手段がリセットされるように、押されている間の前記投与キー(5)が前記搬送機構と一時的に係合されることを特徴とする吸入装置。 - 前記投与キー(5)に対して固定された偏向形状部を備え、該偏向形状部は、前記投与キー(5)が非押し下げ位置から押し下げ位置へと移動している間に前記可撓性のアームまたは可撓性の脚部を前記第2の偏向位置に付勢し、その後、前記投与キー(5)が完全に押し下げられた位置へさらに移動している間に前記可撓性のアームまたは可撓性の脚部を前記第1の非偏向位置内に解放するものであることを特徴とする請求項1に記載の吸入装置。
- 前記偏向形状部が、前記吸入装置(1)の固定部分のはす縁(28)または傾斜面取り形状部によって設けられていることを特徴とする請求項2に記載の吸入装置。
- 前記投与キー(5)がその非動作位置にばね付勢により保持されていることを特徴とする請求項1〜3のいずれか1項に記載の吸入装置。
- 前記搬送機構が前記計量手段に作用する投与レバー(6)を有し、該投与レバー(6)は、前記投与キー(5)が押し下げられた後に前記計量手段の吸入位置にロックされ、前記投与キー(5)が解放されているか否かにかかわらず前記投与レバー(6)は吸入によって解除可能であることを特徴とする請求項1〜4のいずれか1項に記載の吸入装置。
- 前記粉末チャネルと連通する空気ダクト(9)内に吸入作動弁を備え、該吸入作動弁は、前記投与レバーが該吸入動作弁の作用によって解除可能であるように前記投与レバー(6)に動作可能に接続されていることを特徴とする請求項5に記載の吸入装置。
- 前記投与レバー(6)が第1のロック位置、次に第2のロック位置をとることが可能であり、および前記投与レバー(6)が前記第2のロック位置にロックされた後にのみ吸入によって解除可能であることを特徴とする請求項6に記載の吸入装置。
- 前記投与レバー(6)は、前記可撓性のアームまたは可撓性の脚部が前記投与キー(5)のさらなる押し下げで解放されるまで前記投与キー(5)が押し下げられたときに、前記第2のロック位置をとることを特徴とする請求項7に記載の吸入装置。
- 前記可撓性のアームまたは可撓性の脚部が前記投与キー(5)と一体的に形成されていることを特徴とする請求項1〜8のいずれか1項に記載の吸入装置。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12000353.8 | 2012-01-20 | ||
EP12000353.8A EP2617448A1 (en) | 2012-01-20 | 2012-01-20 | Inhalation device for powdered drugs |
US201261589572P | 2012-01-23 | 2012-01-23 | |
US61/589,572 | 2012-01-23 | ||
PCT/EP2013/000126 WO2013107640A1 (en) | 2012-01-20 | 2013-01-17 | Inhalation device for powdered drugs |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2015503978A JP2015503978A (ja) | 2015-02-05 |
JP6238085B2 true JP6238085B2 (ja) | 2017-11-29 |
Family
ID=45531752
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014552568A Active JP6238085B2 (ja) | 2012-01-20 | 2013-01-17 | 粉末薬剤用吸入装置 |
Country Status (26)
Country | Link |
---|---|
US (1) | US10434268B2 (ja) |
EP (2) | EP2617448A1 (ja) |
JP (1) | JP6238085B2 (ja) |
KR (1) | KR102050613B1 (ja) |
CN (1) | CN104114214B (ja) |
AR (1) | AR090055A1 (ja) |
AU (1) | AU2013211249B2 (ja) |
BR (1) | BR112014017554B1 (ja) |
CA (1) | CA2863504C (ja) |
CL (1) | CL2014001906A1 (ja) |
CO (1) | CO7020897A2 (ja) |
CR (1) | CR20140284A (ja) |
EA (1) | EA201491401A1 (ja) |
EC (1) | ECSP14013540A (ja) |
ES (1) | ES2676821T3 (ja) |
GT (1) | GT201400157A (ja) |
HK (1) | HK1205471A1 (ja) |
IL (1) | IL233346B (ja) |
MX (1) | MX349276B (ja) |
NZ (1) | NZ626317A (ja) |
PE (1) | PE20141340A1 (ja) |
PH (1) | PH12014501647A1 (ja) |
SG (1) | SG11201404244UA (ja) |
TW (1) | TW201334819A (ja) |
UY (1) | UY34581A (ja) |
WO (1) | WO2013107640A1 (ja) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
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USD296605S (en) * | 1985-01-31 | 1988-07-12 | Ecotat System Company | Combination outer garment and tent |
EP2835146B1 (en) | 2013-08-09 | 2020-09-30 | Boehringer Ingelheim International GmbH | Nebulizer |
DK3139983T3 (da) | 2014-05-07 | 2023-09-11 | Boehringer Ingelheim Int | Beholder og indikatoranordning, samt forstøver |
JP6580070B2 (ja) | 2014-05-07 | 2019-09-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 容器、ネブライザ、及び使用 |
HUE055604T2 (hu) | 2014-05-07 | 2021-12-28 | Boehringer Ingelheim Int | Porlasztó |
HUE052394T2 (hu) * | 2014-06-30 | 2021-04-28 | Chiesi Farm Spa | Porinhalátor |
US10561806B2 (en) * | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
MX2018014754A (es) | 2016-06-24 | 2019-04-29 | Avent Inc | Indicador de relleno de bolo. |
ES2907984T3 (es) * | 2016-12-06 | 2022-04-27 | Norton Waterford Ltd | Dispositivo de inhalación con módulo electrónico integrado |
GB2576789B (en) * | 2018-09-03 | 2020-11-18 | Ttp Plc | Medicament delivery device with medicament strip release mechanism |
FR3092252B1 (fr) * | 2019-02-04 | 2021-01-22 | Aptar France Sas | Dispositif de distribution de produit fluide synchronisé avec l'inhalation |
USD877322S1 (en) * | 2019-08-03 | 2020-03-03 | Optimist Inhaler, LLC | Flip-top metered-dose inhaler |
WO2021026432A1 (en) | 2019-08-07 | 2021-02-11 | Saudi Arabian Oil Company | Determination of geologic permeability correlative with magnetic permeability measured in-situ |
US11879328B2 (en) | 2021-08-05 | 2024-01-23 | Saudi Arabian Oil Company | Semi-permanent downhole sensor tool |
US11860077B2 (en) | 2021-12-14 | 2024-01-02 | Saudi Arabian Oil Company | Fluid flow sensor using driver and reference electromechanical resonators |
US11867049B1 (en) | 2022-07-19 | 2024-01-09 | Saudi Arabian Oil Company | Downhole logging tool |
US11913329B1 (en) | 2022-09-21 | 2024-02-27 | Saudi Arabian Oil Company | Untethered logging devices and related methods of logging a wellbore |
Family Cites Families (11)
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GB8909891D0 (en) * | 1989-04-28 | 1989-06-14 | Riker Laboratories Inc | Device |
US5388572A (en) * | 1993-10-26 | 1995-02-14 | Tenax Corporation (A Connecticut Corp.) | Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same |
NZ502870A (en) * | 1995-06-21 | 2001-06-29 | Asta Medica Ag | Inhaler for powdered medicaments comprising a visual display device to indicate the discharge status of the inhaler |
US6698422B2 (en) | 2001-03-12 | 2004-03-02 | Birdsong Medical Devices, Inc. | Canister inhaler having a spacer and easy to operate lever mechanism and a flexible, elastic mouthpiece |
DE10129703A1 (de) * | 2001-06-22 | 2003-01-02 | Sofotec Gmbh & Co Kg | Zerstäubungssystem für eine Pulvermischung und Verfahren für Trockenpulverinhalatoren |
AU2003272935C1 (en) * | 2002-10-11 | 2009-06-25 | Otsuka Pharmaceutical Co., Ltd. | Powder inhalation device |
DE602005023690D1 (de) * | 2004-07-16 | 2010-11-04 | Almirall Sa | Inhalator für die Abgabe von pharmzeutischen Pulver, und ein Pulverkassette zur Verwendung mit diesem Inhalator |
GB0507100D0 (en) * | 2005-04-08 | 2005-05-11 | Team Holdings Uk Ltd | Improvements in or relating to inhalers |
GB0625303D0 (en) | 2006-12-19 | 2007-01-24 | Jagotec Ag | Improvements in and relating to metered dose inhalers |
EP2063940B1 (en) | 2006-12-22 | 2012-01-11 | Almirall, S.A. | Inhalation device for drugs in powder form |
US8720433B2 (en) | 2008-05-07 | 2014-05-13 | Map Pharmaceuticals, Inc. | Dose counter with lockout mechanism |
-
2012
- 2012-01-20 EP EP12000353.8A patent/EP2617448A1/en not_active Withdrawn
-
2013
- 2013-01-17 WO PCT/EP2013/000126 patent/WO2013107640A1/en active Application Filing
- 2013-01-17 PE PE2014001123A patent/PE20141340A1/es not_active Application Discontinuation
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