JP6211513B2 - 自己免疫疾患の治療のための組成物及び方法 - Google Patents

自己免疫疾患の治療のための組成物及び方法 Download PDF

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JP6211513B2
JP6211513B2 JP2014508569A JP2014508569A JP6211513B2 JP 6211513 B2 JP6211513 B2 JP 6211513B2 JP 2014508569 A JP2014508569 A JP 2014508569A JP 2014508569 A JP2014508569 A JP 2014508569A JP 6211513 B2 JP6211513 B2 JP 6211513B2
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interferon
antibody
patient
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JP2014519487A (ja
JP2014519487A5 (https=
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アリッサ， エム． モリモト，
アリッサ， エム． モリモト，
ジャックリーン マックブライド，
ジャックリーン マックブライド，
リチャード ボアメニュー，
リチャード ボアメニュー，
ヨルン ドラッパ，
ヨルン ドラッパ，
ロメオ マシューカ，
ロメオ マシューカ，
ウィリアム， ディー． ケネディ，
ウィリアム， ディー． ケネディ，
マイケル， ジェー． タウンゼンド，
マイケル， ジェー． タウンゼンド，
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Genentech Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/686—Anti-idiotype
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Organic Chemistry (AREA)
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  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Urology & Nephrology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
JP2014508569A 2011-04-26 2012-04-26 自己免疫疾患の治療のための組成物及び方法 Expired - Fee Related JP6211513B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161479314P 2011-04-26 2011-04-26
US61/479,314 2011-04-26
US201161582179P 2011-12-30 2011-12-30
US61/582,179 2011-12-30
PCT/US2012/035313 WO2012149228A1 (en) 2011-04-26 2012-04-26 Compositions and method for treating autoimmune diseases

Publications (3)

Publication Number Publication Date
JP2014519487A JP2014519487A (ja) 2014-08-14
JP2014519487A5 JP2014519487A5 (https=) 2015-06-18
JP6211513B2 true JP6211513B2 (ja) 2017-10-11

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JP2014508569A Expired - Fee Related JP6211513B2 (ja) 2011-04-26 2012-04-26 自己免疫疾患の治療のための組成物及び方法

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Country Link
US (1) US20140056889A1 (https=)
EP (1) EP2701742A4 (https=)
JP (1) JP6211513B2 (https=)
KR (1) KR20140048877A (https=)
AR (1) AR086074A1 (https=)
AU (1) AU2012249601A1 (https=)
CA (1) CA2834203A1 (https=)
WO (1) WO2012149228A1 (https=)

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WO2007127756A2 (en) 2006-04-24 2007-11-08 Genentech, Inc. Methods and compositions for detecting autoimmune disorders
CN103732251A (zh) * 2011-05-25 2014-04-16 米迪缪尼有限公司 用针对干扰素-α的抗体治疗全身性红斑狼疮、硬皮病以及肌炎的方法
WO2013101771A2 (en) * 2011-12-30 2013-07-04 Genentech, Inc. Compositions and method for treating autoimmune diseases
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
AU2013256064B2 (en) 2012-05-03 2018-01-04 Alcon Inc. Pharmaceutical nanoparticles showing improved mucosal transport
KR102310775B1 (ko) 2012-05-03 2021-10-07 칼라 파마슈티컬스, 인크. 개선된 점막 수송을 나타내는 제약 나노입자
JP6669499B2 (ja) 2013-02-15 2020-03-18 カラ ファーマシューティカルズ インコーポレイテッド 治療用化合物
JP2016510000A (ja) 2013-02-20 2016-04-04 カラ ファーマシューティカルズ インコーポレイテッド 治療用化合物およびその使用
US9688688B2 (en) 2013-02-20 2017-06-27 Kala Pharmaceuticals, Inc. Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof
US9890173B2 (en) 2013-11-01 2018-02-13 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
NZ719185A (en) 2013-11-01 2017-11-24 Kala Pharmaceuticals Inc Crystalline forms of therapeutic compounds and uses thereof
GB201501613D0 (en) 2015-01-30 2015-03-18 Ucb Biopharma Sprl Treatment of autoimmune disorders with CD154 antibodies
RU2756109C2 (ru) 2016-03-10 2021-09-28 Виела Байо, Инк. Связывающие ilt7 молекулы и способы их применения
KR20190051010A (ko) 2016-09-08 2019-05-14 칼라 파마슈티컬스, 인크. 치료 화합물의 결정형 및 그의 용도
AU2017324713B2 (en) 2016-09-08 2020-08-13 KALA BIO, Inc. Crystalline forms of therapeutic compounds and uses thereof
EP3509423A4 (en) 2016-09-08 2020-05-13 Kala Pharmaceuticals, Inc. CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF
WO2018136625A2 (en) * 2017-01-20 2018-07-26 Children's Medical Center Corporation Compositions and methods for treating diseases characterized by reactive microglia mediated synapse loss
US12486320B1 (en) * 2018-01-15 2025-12-02 Washington University Compositions and methods for treatment of central nervous system (CNS) autoimmune associated diseases or disorders
US11769592B1 (en) 2018-10-07 2023-09-26 Cerner Innovation, Inc. Classifier apparatus with decision support tool
US11749404B1 (en) * 2018-10-08 2023-09-05 Cerner Innovation, Inc. Decision support tool for venous thromboembolism (VTE)
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KR102308865B1 (ko) * 2019-02-08 2021-10-05 서울대학교산학협력단 전신 홍반 루푸스 산모의 임신 위험도를 평가하는 방법
JP7494416B2 (ja) * 2019-10-31 2024-06-04 義知 本田 血管老化予測方法、疾患リスク予測方法、血管老化予測用バイオマーカー、疾患用バイオマーカー、測定キット、及び、診断装置
WO2021113702A1 (en) * 2019-12-06 2021-06-10 Viela Bio, Inc. Methods of treatment using ilt7 binding proteins
CN114836534A (zh) * 2021-06-08 2022-08-02 中国医学科学院北京协和医院 Samd9l基因突变作为i型干扰素病诊断的标志物及其应用
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JP2014519487A (ja) 2014-08-14
CA2834203A1 (en) 2012-11-01
EP2701742A1 (en) 2014-03-05
AU2012249601A1 (en) 2013-05-09
AR086074A1 (es) 2013-11-13
KR20140048877A (ko) 2014-04-24
US20140056889A1 (en) 2014-02-27
WO2012149228A1 (en) 2012-11-01
EP2701742A4 (en) 2015-03-18

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