JP6206939B2 - 肝がん幹細胞阻害剤 - Google Patents

肝がん幹細胞阻害剤 Download PDF

Info

Publication number
JP6206939B2
JP6206939B2 JP2012224722A JP2012224722A JP6206939B2 JP 6206939 B2 JP6206939 B2 JP 6206939B2 JP 2012224722 A JP2012224722 A JP 2012224722A JP 2012224722 A JP2012224722 A JP 2012224722A JP 6206939 B2 JP6206939 B2 JP 6206939B2
Authority
JP
Japan
Prior art keywords
cells
disulfiram
liver cancer
cancer
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2012224722A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013100268A5 (enExample
JP2013100268A (ja
Inventor
哲博 千葉
哲博 千葉
英一郎 鈴木
英一郎 鈴木
文彦 金井
文彦 金井
收 横須賀
收 横須賀
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chiba University NUC
Original Assignee
Chiba University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiba University NUC filed Critical Chiba University NUC
Priority to JP2012224722A priority Critical patent/JP6206939B2/ja
Publication of JP2013100268A publication Critical patent/JP2013100268A/ja
Publication of JP2013100268A5 publication Critical patent/JP2013100268A5/ja
Application granted granted Critical
Publication of JP6206939B2 publication Critical patent/JP6206939B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2012224722A 2011-10-11 2012-10-10 肝がん幹細胞阻害剤 Expired - Fee Related JP6206939B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2012224722A JP6206939B2 (ja) 2011-10-11 2012-10-10 肝がん幹細胞阻害剤

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011223639 2011-10-11
JP2011223639 2011-10-11
JP2012224722A JP6206939B2 (ja) 2011-10-11 2012-10-10 肝がん幹細胞阻害剤

Publications (3)

Publication Number Publication Date
JP2013100268A JP2013100268A (ja) 2013-05-23
JP2013100268A5 JP2013100268A5 (enExample) 2015-11-26
JP6206939B2 true JP6206939B2 (ja) 2017-10-04

Family

ID=48621310

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012224722A Expired - Fee Related JP6206939B2 (ja) 2011-10-11 2012-10-10 肝がん幹細胞阻害剤

Country Status (1)

Country Link
JP (1) JP6206939B2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016111307A1 (ja) * 2015-01-06 2016-07-14 国立大学法人 東京大学 がん微小環境又は炎症性微小環境の構成細胞の制御剤
KR101765575B1 (ko) * 2015-02-02 2017-08-07 연세대학교 산학협력단 알데히드 억제제 및 비구아나이드 계열 화합물을 포함하는 암 줄기세포의 성장 억제용 약학적 조성물
US20220313647A1 (en) 2019-07-25 2022-10-06 Tokyo University Of Science Foundation Agent for treating, preventing or improving psychiatric and nervous system disorders or symptoms

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL122892A0 (en) * 1998-01-11 1998-08-16 Yeda Res & Dev Pharmaceutical compositions comprising a thiocarbamate

Also Published As

Publication number Publication date
JP2013100268A (ja) 2013-05-23

Similar Documents

Publication Publication Date Title
US9782386B2 (en) CDC7 kinase inhibitors and uses thereof
JP7013369B2 (ja) Ezh2阻害剤により卵巣の悪性ラブドイド腫瘍(mrto)/高カルシウム血症型の卵巣の小細胞癌(sccoht)を処置するための方法
JP4238728B2 (ja) ヒストンデアセチラーゼ阻害剤の医薬用途ならびにその抗腫瘍効果の評価方法
UA125614C2 (uk) Комбінована терапія для лікування або профілактики пухлин
JP7015856B2 (ja) がん治療のための組成物及び方法
EP1718322B1 (en) Synergistic compositions with fk-228
EP2433636A1 (en) Treatment of Malignant Diseases
WO2008013966A2 (en) Use of 8-quinolinol and its analogs to target cancer stem cells
Kawakami et al. A novel fusicoccin derivative preferentially targets hypoxic tumor cells and inhibits tumor growth in xenografts
JP6206939B2 (ja) 肝がん幹細胞阻害剤
EP3046560A1 (en) Stem cell modulation ii
CN112513000B (zh) 新型联苯衍生物化合物及其用途
EP3854397A1 (en) Cancer combination therapy using quinoline carboxamide derivative
US10988429B2 (en) Quinochalcone compound and uses thereof for treating cancer or inflammation
EP3070092B1 (en) 3-phenyl-thiazolo[3,2-a]benzimidazole derivatives as aldehyde dehydrogenase 1 (aldh-1) modulators for the treatment of breast cancer or leukemia, and for manipulating cultured aldh-1 positive breast cancer or leukemia cells
JP6452954B2 (ja) 癌転移抑制剤
US10512631B2 (en) Chalcone compounds
CN105541696B (zh) 一种抗肿瘤的化合物及其制备方法和应用
JP7455353B2 (ja) 急性tリンパ芽球性白血病若しくはリンパ腫、又は急性骨髄性白血病治療用医薬組成物
CN103087196B (zh) 胞壁酰二肽-抗cd20免疫偶联物制备方法及应用
TWI734934B (zh) 含4-乙醯基-安卓奎諾-b之組合物用於製備抑制腦癌細胞或腦癌幹細胞生長之藥物的用途
WO2024060520A1 (zh) 一种防治肿瘤的药物及其用途
WO2022215622A1 (ja) ピロールイミダゾールポリアミド化合物を有効成分とするがん転移阻害剤
WO2025001852A1 (zh) 多肽偶联物、包含所述多肽偶联物的药物组合物及其用途
CN121059588A (zh) 一种抗肿瘤药物及其应用

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20151008

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20151008

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20160712

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20160909

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20161110

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20170222

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170522

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20170626

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20170822

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20170831

R150 Certificate of patent or registration of utility model

Ref document number: 6206939

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees