JP6189945B2 - 癌および自己免疫疾患の治療に有用な可逆性共有結合ピロロ−またはピラゾロピリミジン - Google Patents

癌および自己免疫疾患の治療に有用な可逆性共有結合ピロロ−またはピラゾロピリミジン Download PDF

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JP6189945B2
JP6189945B2 JP2015517370A JP2015517370A JP6189945B2 JP 6189945 B2 JP6189945 B2 JP 6189945B2 JP 2015517370 A JP2015517370 A JP 2015517370A JP 2015517370 A JP2015517370 A JP 2015517370A JP 6189945 B2 JP6189945 B2 JP 6189945B2
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amino
pyrimidin
carbonyl
pyrazolo
methyl
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JP2015519401A (ja
JP2015519401A5 (enExample
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マイケル ゴールドスタイン，デイビッド
マイケル ゴールドスタイン，デイビッド
バーナー，ブレット
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プリンシピア バイオファーマ インコーポレイテッド
プリンシピア バイオファーマ インコーポレイテッド
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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JP2015517370A 2012-06-18 2013-06-11 癌および自己免疫疾患の治療に有用な可逆性共有結合ピロロ−またはピラゾロピリミジン Active JP6189945B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261661203P 2012-06-18 2012-06-18
US61/661,203 2012-06-18
PCT/US2013/045266 WO2013191965A1 (en) 2012-06-18 2013-06-11 Reversible covalent pyrrolo- or pyrazolopyrimidines useful for the treatment cancer and autoimmune diseases

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JP2015519401A JP2015519401A (ja) 2015-07-09
JP2015519401A5 JP2015519401A5 (enExample) 2016-08-04
JP6189945B2 true JP6189945B2 (ja) 2017-08-30

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US (1) US20160045503A1 (enExample)
EP (1) EP2861599B1 (enExample)
JP (1) JP6189945B2 (enExample)
KR (1) KR102150432B1 (enExample)
CN (1) CN104487441B (enExample)
AU (1) AU2013277582B2 (enExample)
CA (1) CA2874461C (enExample)
DK (1) DK2861599T3 (enExample)
ES (1) ES2776175T3 (enExample)
MX (1) MX368112B (enExample)
WO (1) WO2013191965A1 (enExample)

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