JP6182237B2 - Composition for killing pests - Google Patents

Description

  The present invention relates to a composition for killing a pest by maintaining the cooling state of the pest.

  Conventionally, insecticide compositions containing active ingredients such as pyrethroids have been used to control pests. However, the use of insecticide compositions containing these drugs has led to the problem that pesticides develop resistance to the pests, resulting in a decrease in the control effect. Insecticides containing new drugs as active ingredients The development of agent compositions has been desired.

  Under such circumstances, various studies have been made on active ingredients replacing pyrethroids and the like. For example, a pest control agent containing a compound having a pest anesthetic effect such as n-pentane (for example, see Patent Document 1 below) ), Aerosol spray type insecticide composition containing trichlorotrifluoroethane or the like as an active ingredient (for example, see Patent Document 2 below), pest control agent containing 2,3-dihydrodecafluoropentane as an active ingredient (for example, the following) Patent Document 3) is known.

JP-A-4-120003 Japanese Unexamined Patent Publication No. 62-132803 JP-A-9-309802

  The above-mentioned patent document shows that when an insecticide composition is sprayed on a pest as an aerosol composition or the like, the pest is paralyzed (knocked down) due to the cooling action of the active ingredient and temporarily stops moving. Yes. However, even if the pest is temporarily paralyzed, it may be revived after a while. Therefore, when exterminating the pests, it is required not only to bring the pests into a paralyzed state but also to kill them completely.

  In addition, when the insecticide composition contains pentane as in the above-mentioned Patent Document 1, if the insecticide composition is used in a large amount as an aerosol composition in a room or a warehouse, there is a fear of ignition or explosion, It is also required to ensure sufficient safety for the insecticide composition.

  This invention is made | formed in view of the said subject, and it aims at providing the composition for killing a pest which has the high insecticidal effect by a cooling effect, ensuring sufficient safety | security.

  As a result of intensive studies on the above problems, the present inventors have conceived that insect pests are killed by enhancing the cooling action, and by using a specific compound and myristic acid alkyl ester in combination, sufficient safety can be obtained. The present inventors have found that a higher insecticidal effect can be obtained by maintaining the time during which the pests are kept in a cooled state while securing them.

  That is, the first aspect of the present invention is a composition containing dimethyl ether and myristic acid alkyl ester for killing a pest by maintaining the cooling state of the pest.

  According to the composition of the first aspect of the present invention, by using dimethyl ether and myristic acid alkyl ester in combination, the cooling action against pests can be enhanced while ensuring sufficient safety. According to such a composition, since it becomes easy to maintain the cooling state of a pest and the time (cooling duration) during which the pest is cooled can be increased as compared with the conventional case, the pest is brought to a paralyzed state. Not only can it be killed completely. Therefore, according to the composition which concerns on the 1st aspect of this invention, the high insecticidal effect by a cooling effect | action can be acquired, ensuring sufficient safety | security.

  Moreover, the 2nd aspect of this invention is a composition for containing the hydrofluoro olefin and myristic acid alkylester, and maintaining the cooling state of a pest and killing the pest.

  According to the composition which concerns on the 2nd aspect of this invention, the cooling effect | action with respect to a pest can be strengthened, ensuring sufficient safety | security by using together a hydrofluoro olefin and myristic acid alkylester. According to such a composition, it becomes easy to sustain the cooling state of the pest, and the time during which the pest is cooled (cooling duration) can be increased as compared with the conventional case. Therefore, the pest is brought into a paralyzed state. Not only can it be killed, it can be killed completely. Therefore, according to the composition which concerns on the 2nd aspect of this invention, the high insecticidal effect by a cooling effect | action can be acquired, ensuring sufficient safety | security.

  In the composition according to the present invention, the myristate alkyl ester is preferably at least one selected from the group consisting of methyl myristate, propyl myristate, and isopropyl myristate. Thereby, since the cooling effect | action with respect to a pest can be further strengthened and the sustainability of cooling time can further be extended, a still higher insecticidal effect can be acquired, ensuring sufficient safety | security.

According to the present invention, by using dimethyl ether and myristic acid alkyl ester in combination, or by using hydrofluoroolefin and myristic acid alkyl ester in combination, dimethyl ether or hydrofluoroolefin and myristic acid alkyl ester cooperate. Due to the action, it is possible to provide a composition for killing pests, which has a high insecticidal effect due to the cooling action while ensuring sufficient safety.
Moreover, according to the composition which concerns on this invention, the new effect of extending the cooling holding time of a pest is exhibited, and it becomes possible to obtain a high insecticidal effect. For example, when the composition according to the present invention is sprayed against a pest for 5 seconds at a spraying distance of 30 cm and a spray amount of 4 ml / second, the cooling and holding time of the pest at −40 ° C. or less after the supply of the composition to the pest is stopped. Is 60 seconds or more.

It is a figure which shows the result of having measured the time-dependent change of the body surface temperature of a test insect.

  Hereinafter, a composition according to an embodiment of the present invention (a composition for killing pests) and an insecticidal method using the composition will be described in detail.

  The composition according to the present embodiment has an effect of enhancing the cooling action against pests, and is composed of a composition that completely kills the pests by the enhanced cooling action.

  The composition according to the present embodiment contains, as active ingredients, at least one compound selected from the group consisting of dimethyl ether and hydrofluoroolefin, and myristic acid alkyl ester. For example, the composition according to the first embodiment contains dimethyl ether and myristic acid alkyl ester. The composition according to the second embodiment contains hydrofluoroolefin and myristic acid alkyl ester. Note that the composition according to the present embodiment may contain both dimethyl ether and hydrofluoroolefin.

  Dimethyl ether and hydrofluoroolefin itself have a cooling action against some pests, and also act as a propellant in the composition according to this embodiment. Therefore, the composition according to the present embodiment can be used by spraying as an aerosol composition, and may not contain other propellants. However, the use of a known propellant is not excluded unless the effects of the present invention are impaired.

  The content of dimethyl ether is preferably 10% by mass or more, more preferably 50 to 99% by mass based on the entire composition.

Examples of the hydrofluoroolefin include hydrofluoropropene, such as 1,3,3,3-tetrafluoropropene, 2,3,3,3-tetrafluoropropene, 2,3,3-trifluoropropene, 3 , 3,3-trifluoropropene and the like can be used. Among these, 1,3,3,3-tetrafluoropropene is preferable because it is particularly excellent in the cooling action resulting from the cooperative action with myristic acid alkyl ester.
In addition, as 1,3,3,3-tetrafluoropropene, (E) -1,3,3,3-tetrafluoroprop-1-ene (also known as “trans-1,3,3,3-tetrafluoro”) is used. Propene "," HFO-1234ze "). Thereby, since the cooling effect | action with respect to a pest can be further strengthened and the sustainability of cooling time can further be extended, a still higher insecticidal effect can be acquired, ensuring sufficient safety | security.

  The content of the hydrofluoroolefin is preferably 10% by mass or more, more preferably 50 to 99% by mass, based on the entire composition.

  As the myristate alkyl ester, methyl myristate, propyl myristate, and isopropyl myristate are preferable, and one of these may be used alone, or a plurality of may be used in combination.

  The content of myristic acid alkyl ester is preferably 0.1% by mass or more, more preferably 0.1 to 10% by mass, based on the entire composition.

  Further, the content of myristic acid alkyl ester is preferably 0.1% by mass or more, and 0.1 to 10% by mass with respect to the content of dimethyl ether or hydrofluoroolefin (the total amount when both are used). More preferred.

  The composition which concerns on this embodiment may be the aspect which consists of at least 1 type of compound chosen from the group which consists of dimethyl ether and hydrofluoro olefin, and myristic acid alkylester. In addition to the above components, the composition according to this embodiment may contain a necessary base used for formulation as long as the effects of the present invention are exhibited. Alcohols; polyhydric alcohols such as glycerin and ethylene glycol; linear, branched or cyclic paraffins; kerosene; water; nonionic, anionic or cationic surfactants, plant essential oils, antioxidants such as butylhydroxytoluene A stabilizer such as citric acid or ascorbic acid; an inorganic powder such as talc or silicic acid;

The composition according to the present embodiment is, for example, pyrethrin, allethrin, phthalthrin, resmethrin, framethrin, phenothrin, permethrin, empentrin, praretrin, ciphenothrin, imiprothrin, transfluthrin, as long as the effect of the invention is not impaired. Pyrethroid insecticides such as metfurthrin; organophosphorus insecticides such as fenitrothion, dichlorvos, chlorpyrifosmethyl, diazinon, fenthion; carbamate insecticides such as carbaryl, propoxur; insecticides such as metoprene, pyriproxyfen, methoxadiazone, fipronil, amidoflumet Although an agent may be contained, a pest can be killed without containing an insecticide as an active ingredient.
Further, it does not exclude the inclusion of bactericides (antifungal agents), deodorants, fragrances (fragrances), pigments and the like.

  The composition according to this embodiment can be applied to various pests, but is particularly effective against large pests such as cockroaches such as German cockroaches, black cockroaches, and cockroaches such as cockroaches, and large pests such as centipedes.

  In the insecticidal method according to the present embodiment, the cooling state is maintained by bringing the composition into contact with a pest to completely kill it. For example, the above composition can be pressurized and filled in a pressure-resistant container equipped with an injection device as an aerosol composition, and the composition can be brought into contact with the pest by spraying the composition against the pest, thereby controlling the pest.

  In the insecticidal method according to the present embodiment, for example, the composition is sprayed as an aerosol composition at a spraying distance of 30 cm and a spraying amount of 4 ml / second toward the pests for 5 seconds. In this case, it is preferable that the cooling holding time of −40 ° C. or less of the pest after the supply of the composition to the pest is 60 seconds or more. Further, the cooling holding time of −40 ° C. or lower is more preferably 90 seconds or longer from the viewpoint of obtaining a higher insecticidal effect. When the composition according to this embodiment contains at least one compound selected from the group consisting of dimethyl ether and hydrofluoroolefin, and myristic acid alkyl ester, these cooling holding times can be easily obtained. In addition, the injection conditions of a composition are not restricted above.

  By the way, when the conventional aerosol composition is used, it is considered that the pest cooling holding time is not sufficiently secured because it is difficult to kill the pests. On the other hand, according to the composition according to the present embodiment, the cooling and holding time of the pest is sufficiently ensured. In this regard, when the composition according to the present embodiment is used, after the supply of the composition to the pests is stopped, the pest temperature tends to gradually increase after continuing to decrease for a certain time. Such a peculiar phenomenon is considered to be a factor for ensuring a sufficient cooling time for the pests.

  According to the composition according to the present embodiment, by using dimethyl ether and myristic acid alkyl ester in combination, or by using hydrofluoroolefin and myristic acid alkyl ester in combination, while ensuring sufficient safety, Cooling action against pests can be enhanced. According to such a composition, since it becomes easy to maintain the cooling state of a pest and can increase the cooling holding time of a pest compared with the past, the pest is not only brought to a paralyzed state but also completely killed. be able to. Therefore, according to the composition which concerns on this embodiment, the high insecticidal effect by a cooling effect | action can be acquired, ensuring sufficient safety | security.

  Hereinafter, the present invention will be described by way of examples. However, the present invention is not limited to these examples.

(Experiment 1: Evaluation of cooling holding time)
A composition containing the components shown in Table 1 was prepared as a sample for evaluation, and equipped with a spray device (a button having a stem diameter of 0.6 mm, an undertap diameter of 2.2 mm, and a diameter of 1.5 mm × 4 holes). A pressurized aerosol container (300 ml) was pressure filled.

  The cooling holding time was evaluated as follows. First, after anesthetizing one test insect (adult black cockroach female), a terminal of a digital thermometer (TM-300 Thermometer, ASONE) was fixed to the body surface of the test insect. Next, the sample for evaluation obtained above was sprayed onto the test insect for 5 seconds (20 ml) at a distance of 30 cm from the spray hole. The test was conducted in an environment with a temperature of 20.5 ° C. and a humidity of 26%. The time-dependent change of the body surface temperature of the test insect after spraying the sample for evaluation was measured. The results are shown in FIG. In addition, the measured value of FIG. 1 is an average value of the temperature of two test insects. The time point at which the supply of the sample for evaluation to the test insect was stopped was defined as an elapsed time of 0 seconds.

As shown in FIG. 1, in Example 1-1 , Reference Example 1-2, and Reference Example 1-3 , it is confirmed that the cooling holding time is sufficiently secured. The holding time of −40 ° C. or lower is 160 seconds in Example 1-1, 120 seconds in Reference Example 1-2, and 100 seconds in Reference Example 1-3.
In Example 1-1 , Reference Example 1-2, and Reference Example 1-3 , after the supply of the sample for evaluation to the test insect was stopped, the temperature of the test insect continued to decrease for a certain time. It is confirmed that it gradually increases. Furthermore, in Example 1-1, it is confirmed that the maximum temperature drop is particularly low.
On the other hand, in Comparative Examples 1-1 to 1-4, after the supply of the sample for evaluation to the test insect was stopped, the temperature immediately started to increase and the cooling holding time was not sufficiently secured, and the temperature was −40 ° C. It is confirmed that the following holding times are all 50 seconds or less.

(Experiment 2: Insecticidal test 1)
Prepare samples for evaluation using isopropyl myristate, (E) -1,3,3,3-tetrafluoropropane-1-ene (HFO-1234ze), nitrogen gas so as to contain the components shown in Table 2 Then, an aerosol container (300 ml) equipped with a spraying device (a button having a stem diameter of 0.6 mm, an under tap diameter of 2.2 mm, and a diameter of 1.5 mm × 4 holes) was pressurized and filled. In Comparative Example 2-2, a spraying device (button having a stem diameter of 0.6 mm, an under tap diameter of 2.2 mm, a diameter of 0.23 mm × one hole nozzle) was used.
The evaluation sample of Reference Example 2-1 contains isopropyl myristate and (E) -1,3,3,3-tetrafluoropropane-1-ene, and the evaluation sample of Comparative Example 2-1 is , (E) -1,3,3,3-tetrafluoropropane-1-ene only, and the sample for evaluation of Comparative Example 2-2 is isopropyl myristate and nitrogen gas (0.5 MPa) Amount).

  The insecticidal test was conducted as follows. The sample for evaluation obtained above was sprayed for 1 second (4 ml) at a distance of 50 cm from the spray hole to one test insect (adult female cockroach) placed in the cup. Thereafter, the test insects were placed in a cylinder having a diameter of 45 cm and a height of 10 cm containing food and water, and the test insects after the evaluation samples were sprayed in an environment of 20.5 ° C. and 26% humidity. The condition (knockdown time (seconds) and mortality after 24 hours (%)) was observed. The same test was performed 5 times for each sample for evaluation. The results are shown in Table 3.

As shown in Table 3, in Comparative Example 2-1, although the test insect was knocked down, the lethality after 24 hours was 0%, and it was confirmed that all the heads were resuscitated. In Comparative Example 2-2, it was confirmed that the test insects did not knock down and survived as they were after 24 hours. On the other hand, as described above, in Reference Example 2-1 in which isopropyl myristate and (E) -1,3,3,3-tetrafluoropropane-1-ene were used together, the insecticidal effect was not observed when used alone, It was confirmed that the test insects knocked down in less than 1 second and died after 24 hours.

(Experiment 3: Insecticidal test 2)
A composition containing the components shown in Table 4 was prepared as an evaluation sample, and equipped with a spray device (a button having a stem diameter of 0.5 mm, an undertap diameter of 1.5 mm, a diameter of 1.2 mm × 4 holes). An aerosol container (300 ml) was pressure filled.

The insecticidal test was conducted as follows. A test insect (one centipede, 7-8 cm) was placed in a cylinder having a diameter of 50 cm and a height of 10 cm, and the evaluation sample obtained above was sprayed for 5 seconds (20 ml) at a distance of 50 cm from the spray hole. . And the state (existence of knockdown and lethality after 24 hours) of the test insect after spraying the sample for evaluation was observed.
The test was repeated twice, and both were knocked down in less than 1 second and confirmed to be dead after 24 hours.

Claims (1)

Containing dimethyl ether and myristic acid alkyl ester,
The content of myristic acid alkyl ester Ri 0.1-10% by mass relative to the content of dimethyl ether,
Contains no propellant other than dimethyl ether,
A composition (excluding insecticidal aerosols containing petroleum solvents) for maintaining the cooling state of the pests and killing the pests .

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