JP6138793B2 - ネットワークに基づく生物学的活性評価のためのシステムおよび方法 - Google Patents

ネットワークに基づく生物学的活性評価のためのシステムおよび方法 Download PDF

Info

Publication number
JP6138793B2
JP6138793B2 JP2014528898A JP2014528898A JP6138793B2 JP 6138793 B2 JP6138793 B2 JP 6138793B2 JP 2014528898 A JP2014528898 A JP 2014528898A JP 2014528898 A JP2014528898 A JP 2014528898A JP 6138793 B2 JP6138793 B2 JP 6138793B2
Authority
JP
Japan
Prior art keywords
biological
activity
nodes
vector
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2014528898A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014532205A (ja
Inventor
フロリアン マルティン,
フロリアン マルティン,
Original Assignee
フィリップ モリス プロダクツ エス アー
フィリップ モリス プロダクツ エス アー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by フィリップ モリス プロダクツ エス アー, フィリップ モリス プロダクツ エス アー filed Critical フィリップ モリス プロダクツ エス アー
Publication of JP2014532205A publication Critical patent/JP2014532205A/ja
Application granted granted Critical
Publication of JP6138793B2 publication Critical patent/JP6138793B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Physiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Biophysics (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2014528898A 2011-09-09 2012-09-07 ネットワークに基づく生物学的活性評価のためのシステムおよび方法 Active JP6138793B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161532972P 2011-09-09 2011-09-09
US61/532,972 2011-09-09
PCT/EP2012/003760 WO2013034300A2 (en) 2011-09-09 2012-09-07 Systems and methods for network-based biological activity assessment

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016241117A Division JP6407242B2 (ja) 2011-09-09 2016-12-13 ネットワークに基づく生物学的活性評価のためのシステムおよび方法

Publications (2)

Publication Number Publication Date
JP2014532205A JP2014532205A (ja) 2014-12-04
JP6138793B2 true JP6138793B2 (ja) 2017-05-31

Family

ID=46963652

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2014528898A Active JP6138793B2 (ja) 2011-09-09 2012-09-07 ネットワークに基づく生物学的活性評価のためのシステムおよび方法
JP2016241117A Active JP6407242B2 (ja) 2011-09-09 2016-12-13 ネットワークに基づく生物学的活性評価のためのシステムおよび方法
JP2018054384A Withdrawn JP2018116729A (ja) 2011-09-09 2018-03-22 ネットワークに基づく生物学的活性評価のためのシステムおよび方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2016241117A Active JP6407242B2 (ja) 2011-09-09 2016-12-13 ネットワークに基づく生物学的活性評価のためのシステムおよび方法
JP2018054384A Withdrawn JP2018116729A (ja) 2011-09-09 2018-03-22 ネットワークに基づく生物学的活性評価のためのシステムおよび方法

Country Status (5)

Country Link
US (1) US20140214336A1 (enExample)
EP (1) EP2754075A2 (enExample)
JP (3) JP6138793B2 (enExample)
CN (2) CN107391961B (enExample)
WO (1) WO2013034300A2 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2608122A1 (en) 2011-12-22 2013-06-26 Philip Morris Products S.A. Systems and methods for quantifying the impact of biological perturbations
CA2877430C (en) 2012-06-21 2021-07-06 Philip Morris Products S.A. Systems and methods for generating biomarker signatures with integrated dual ensemble and generalized simulated annealing techniques
EP2864920B1 (en) 2012-06-21 2023-05-10 Philip Morris Products S.A. Systems and methods for generating biomarker signatures with integrated bias correction and class prediction
JP6397894B2 (ja) * 2013-04-23 2018-09-26 フィリップ モリス プロダクツ エス アー 体系毒物学において機構的ネットワークモデルを用いるためのシステムおよび方法
EP3033721A1 (en) * 2013-08-12 2016-06-22 Philip Morris Products S.A. Systems and methods for crowd-verification of biological networks
CN105612524B (zh) * 2013-09-13 2019-04-02 菲利普莫里斯生产公司 评估生物外源性物质代谢扰动的系统和方法
CN106471508A (zh) * 2014-06-20 2017-03-01 康涅狄格儿童医疗中心 自动化细胞培养系统及对应的方法
CN104298593B (zh) * 2014-09-23 2017-04-26 北京航空航天大学 一种基于复杂网络理论的soa系统可靠性评价方法
KR101721528B1 (ko) * 2015-05-28 2017-03-31 아주대학교산학협력단 질병 네트워크로부터 동반 발병 확률을 제공하는 방법
US20170059554A1 (en) * 2015-09-02 2017-03-02 R. J. Reynolds Tobacco Company Method for monitoring use of a tobacco product
CN107480467B (zh) * 2016-06-07 2020-11-03 王�忠 一种判别或比较药物作用模块的方法
CN107992720B (zh) * 2017-12-14 2021-08-03 浙江工业大学 基于共表达网络的癌症靶向标志物测绘方法
TWI693612B (zh) * 2018-01-10 2020-05-11 國立臺灣師範大學 環境賀爾蒙與人體基因的關聯性運算平台
CN108614536B (zh) * 2018-06-11 2020-10-27 云南中烟工业有限责任公司 一种卷烟制丝工艺关键因素的复杂网络构建方法
US11515005B2 (en) * 2019-02-25 2022-11-29 International Business Machines Corporation Interactive-aware clustering of stable states
CN110706749B (zh) * 2019-09-10 2022-06-10 至本医疗科技(上海)有限公司 一种基于组织器官分化层次关系的癌症类型预测系统和方法
EP4560639A4 (en) 2022-07-22 2025-10-29 Fujifilm Corp INFORMATION PROCESSING DEVICE, OPERATING METHOD FOR INFORMATION PROCESSING DEVICE, AND OPERATING PROGRAM FOR INFORMATION PROCESSING DEVICE
CN115798598B (zh) * 2022-11-16 2023-11-14 大连海事大学 一种基于超图的miRNA-疾病关联预测模型及方法
CN115861275B (zh) * 2022-12-26 2024-02-06 中南大学 细胞计数方法、装置、终端设备及介质
CN118072926B (zh) * 2024-04-17 2024-07-30 吉林大学 医疗机构院科两级感染风险评估系统及方法
CN118899037A (zh) * 2024-10-08 2024-11-05 福建医科大学附属第一医院 太空电离辐射关键分子的识别方法及系统

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6983227B1 (en) * 1995-01-17 2006-01-03 Intertech Ventures, Ltd. Virtual models of complex systems
US20030130798A1 (en) * 2000-11-14 2003-07-10 The Institute For Systems Biology Multiparameter integration methods for the analysis of biological networks
WO2005003368A2 (de) * 2003-07-04 2005-01-13 Siemens Aktiengesellschaft Verfahren, computerprogramm mit programmcode-mitteln und computerprogramm-produkt zur analyse eines regulatorischen genetischen netzwerks einer zelle
US20050086035A1 (en) * 2003-09-02 2005-04-21 Pioneer Hi-Bred International, Inc. Computer systems and methods for genotype to phenotype mapping using molecular network models
JP2007535305A (ja) * 2003-11-24 2007-12-06 ジーン ロジック インコーポレイテッド 分子毒性モデリングのための方法
CA2593355A1 (en) * 2005-01-24 2006-07-27 The Board Of Trustees Of The Leland Stanford Junior University Method for modeling cell signaling systems by means of bayesian networks
DE102005030136B4 (de) * 2005-06-28 2010-09-23 Siemens Ag Verfahren zur rechnergestützten Simulation von biologischen RNA-Interferenz-Experimenten
US20070198653A1 (en) * 2005-12-30 2007-08-23 Kurt Jarnagin Systems and methods for remote computer-based analysis of user-provided chemogenomic data
DE102006031979A1 (de) * 2006-07-11 2008-01-17 Bayer Technology Services Gmbh Verfahren zur Bestimmung des Verhaltens eines biologischen Systems nach einer reversiblen Störung
RU2473555C2 (ru) * 2006-12-19 2013-01-27 ДжинГоу, Инк. Новые способы функционального анализа большого количества экспериментальных данных и групп генов, идентифицированных из указанных данных

Also Published As

Publication number Publication date
CN103782301A (zh) 2014-05-07
JP2014532205A (ja) 2014-12-04
WO2013034300A3 (en) 2013-09-19
JP6407242B2 (ja) 2018-10-17
EP2754075A2 (en) 2014-07-16
WO2013034300A2 (en) 2013-03-14
JP2018116729A (ja) 2018-07-26
US20140214336A1 (en) 2014-07-31
CN107391961B (zh) 2020-11-17
JP2017073163A (ja) 2017-04-13
CN103782301B (zh) 2017-05-17
CN107391961A (zh) 2017-11-24

Similar Documents

Publication Publication Date Title
JP6407242B2 (ja) ネットワークに基づく生物学的活性評価のためのシステムおよび方法
JP6335260B2 (ja) ネットワークに基づく生物学的活性評価のためのシステムおよび方法
US20210397995A1 (en) Systems and methods relating to network-based biomarker signatures
JP6251370B2 (ja) トポロジーネットワーク攪乱を特徴づけるためのシステムおよび方法
HK1197698B (en) Systems and methods for network-based biological activity assessment
HK1197698A (en) Systems and methods for network-based biological activity assessment
HK1211360B (zh) 与基於网络的生物标记签名相关的系统和方法
HK1219549A1 (zh) 在系统毒理学中使用机理网络模型的系统和方法
HK1196688A (en) Systems and methods for network-based biological activity assessment
HK1198594B (en) Systems and methods for characterizing topological network perturbations

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20150902

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20160714

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20161012

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20161213

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20170330

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20170426

R150 Certificate of patent or registration of utility model

Ref document number: 6138793

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250