CN107391961B - 用于基于网络的生物活性评估的系统与方法 - Google Patents

用于基于网络的生物活性评估的系统与方法 Download PDF

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CN107391961B
CN107391961B CN201710237916.2A CN201710237916A CN107391961B CN 107391961 B CN107391961 B CN 107391961B CN 201710237916 A CN201710237916 A CN 201710237916A CN 107391961 B CN107391961 B CN 107391961B
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CN107391961A (zh
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F·马丁
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Philip Morris Products SA
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    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
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    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks

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CN201710237916.2A 2011-09-09 2012-09-07 用于基于网络的生物活性评估的系统与方法 Active CN107391961B (zh)

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US201161532972P 2011-09-09 2011-09-09
US61/532,972 2011-09-09
CN201280043499.3A CN103782301B (zh) 2011-09-09 2012-09-07 用于基于网络的生物活性评估的系统与方法

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US (1) US20140214336A1 (enExample)
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EP2608122A1 (en) 2011-12-22 2013-06-26 Philip Morris Products S.A. Systems and methods for quantifying the impact of biological perturbations
CA2877430C (en) 2012-06-21 2021-07-06 Philip Morris Products S.A. Systems and methods for generating biomarker signatures with integrated dual ensemble and generalized simulated annealing techniques
EP2864920B1 (en) 2012-06-21 2023-05-10 Philip Morris Products S.A. Systems and methods for generating biomarker signatures with integrated bias correction and class prediction
JP6397894B2 (ja) * 2013-04-23 2018-09-26 フィリップ モリス プロダクツ エス アー 体系毒物学において機構的ネットワークモデルを用いるためのシステムおよび方法
EP3033721A1 (en) * 2013-08-12 2016-06-22 Philip Morris Products S.A. Systems and methods for crowd-verification of biological networks
CN105612524B (zh) * 2013-09-13 2019-04-02 菲利普莫里斯生产公司 评估生物外源性物质代谢扰动的系统和方法
CN106471508A (zh) * 2014-06-20 2017-03-01 康涅狄格儿童医疗中心 自动化细胞培养系统及对应的方法
CN104298593B (zh) * 2014-09-23 2017-04-26 北京航空航天大学 一种基于复杂网络理论的soa系统可靠性评价方法
KR101721528B1 (ko) * 2015-05-28 2017-03-31 아주대학교산학협력단 질병 네트워크로부터 동반 발병 확률을 제공하는 방법
US20170059554A1 (en) * 2015-09-02 2017-03-02 R. J. Reynolds Tobacco Company Method for monitoring use of a tobacco product
CN107480467B (zh) * 2016-06-07 2020-11-03 王�忠 一种判别或比较药物作用模块的方法
CN107992720B (zh) * 2017-12-14 2021-08-03 浙江工业大学 基于共表达网络的癌症靶向标志物测绘方法
TWI693612B (zh) * 2018-01-10 2020-05-11 國立臺灣師範大學 環境賀爾蒙與人體基因的關聯性運算平台
CN108614536B (zh) * 2018-06-11 2020-10-27 云南中烟工业有限责任公司 一种卷烟制丝工艺关键因素的复杂网络构建方法
US11515005B2 (en) * 2019-02-25 2022-11-29 International Business Machines Corporation Interactive-aware clustering of stable states
CN110706749B (zh) * 2019-09-10 2022-06-10 至本医疗科技(上海)有限公司 一种基于组织器官分化层次关系的癌症类型预测系统和方法
EP4560639A4 (en) 2022-07-22 2025-10-29 Fujifilm Corp INFORMATION PROCESSING DEVICE, OPERATING METHOD FOR INFORMATION PROCESSING DEVICE, AND OPERATING PROGRAM FOR INFORMATION PROCESSING DEVICE
CN115798598B (zh) * 2022-11-16 2023-11-14 大连海事大学 一种基于超图的miRNA-疾病关联预测模型及方法
CN115861275B (zh) * 2022-12-26 2024-02-06 中南大学 细胞计数方法、装置、终端设备及介质
CN118072926B (zh) * 2024-04-17 2024-07-30 吉林大学 医疗机构院科两级感染风险评估系统及方法
CN118899037A (zh) * 2024-10-08 2024-11-05 福建医科大学附属第一医院 太空电离辐射关键分子的识别方法及系统

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US20030130798A1 (en) * 2000-11-14 2003-07-10 The Institute For Systems Biology Multiparameter integration methods for the analysis of biological networks
WO2005003368A2 (de) * 2003-07-04 2005-01-13 Siemens Aktiengesellschaft Verfahren, computerprogramm mit programmcode-mitteln und computerprogramm-produkt zur analyse eines regulatorischen genetischen netzwerks einer zelle
US20050086035A1 (en) * 2003-09-02 2005-04-21 Pioneer Hi-Bred International, Inc. Computer systems and methods for genotype to phenotype mapping using molecular network models
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CA2593355A1 (en) * 2005-01-24 2006-07-27 The Board Of Trustees Of The Leland Stanford Junior University Method for modeling cell signaling systems by means of bayesian networks
DE102005030136B4 (de) * 2005-06-28 2010-09-23 Siemens Ag Verfahren zur rechnergestützten Simulation von biologischen RNA-Interferenz-Experimenten
US20070198653A1 (en) * 2005-12-30 2007-08-23 Kurt Jarnagin Systems and methods for remote computer-based analysis of user-provided chemogenomic data
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CN103782301A (zh) 2014-05-07
JP2014532205A (ja) 2014-12-04
WO2013034300A3 (en) 2013-09-19
JP6407242B2 (ja) 2018-10-17
EP2754075A2 (en) 2014-07-16
WO2013034300A2 (en) 2013-03-14
JP2018116729A (ja) 2018-07-26
US20140214336A1 (en) 2014-07-31
JP2017073163A (ja) 2017-04-13
JP6138793B2 (ja) 2017-05-31
CN103782301B (zh) 2017-05-17
CN107391961A (zh) 2017-11-24

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