JP6109683B2 - Foam antibacterial composition - Google Patents

Description

  The present invention relates to a foamy antibacterial composition for wiping the surface of a Western-style toilet such as a toilet seat surface and a toilet wall surface for antibacterial purposes.

Recently, the number of people who are reluctant to use the toilet seat of a Western-style toilet used by others has increased, and it has become natural to wipe the toilet seat before use. Various cleaners for this purpose are known (see Patent Documents 1 and 2).
In order to use these cleaners, first, an antibacterial agent is applied to toilet paper, the toilet seat and the like are wiped off, and the used toilet paper is poured into the toilet and discarded. However, since toilet paper dissolves in water, the cleaner has been devised, for example, to increase the alcohol concentration to 10% by mass or more so that the toilet paper is not easily dissolved (see Patent Document 1).
Moreover, although the composition (refer patent document 2) containing chitosan and a quaternary ammonium salt is known as a toilet seat cleaner, even if it used, it turned out that the bacteria of a toilet seat cannot fully be removed. For this reason, attempts were made to increase the concentration of the disinfectant, but recently, the number of people with sensitive skin has increased, and some people have redness on their skin, and it has not been possible to increase the amount of antibacterial agents. Therefore, there is a growing demand for cleaners that can easily sterilize toilet seats using toilet paper.

Japanese Patent Laid-Open No. 11-061199 JP-A-11-001700

  The present invention is an antibacterial composition capable of producing antibacterial action with a minimum amount of quaternary ammonium salt without the toilet paper being disintegrated by wiping for the purpose of antibacterial purposes over a wide area such as a toilet seat of a Western-style toilet The issue is to provide

The inventors of the present invention have found that the antibacterial composition can be formed into a foam shape so that the antibacterial composition can be uniformly applied to the surface of a toilet seat and the like, so that a chitosan coating film can be formed uniformly. It was found that the antibacterial action can be exerted to the maximum with the concentration of the limited quaternary ammonium salt. In order to make it more foamy, it was found that a composition containing chitosan, a quaternary ammonium salt, and alcohols, and that the content of the alcohols should be a specific amount, and the present invention was completed. It came to do.
That is, this invention relates to the foamy antibacterial composition characterized by containing the following (A), (B), and (C).
(A) Chitosan (B) 0.001 to 0.10% by mass of quaternary ammonium salt (C) 10 to 30% by mass of alcohol Further, the content of the alcohol is 15 to 25% by mass The quaternary ammonium salt is preferably benzalkonium chloride, and the alcohol is preferably ethanol.

  The present invention is a foam-like antibacterial composition formed on toilet paper, and toilet paper does not collapse even if the toilet seat is wiped off. It can be wiped off sufficiently and can exhibit a sufficient antibacterial effect with a minimum of antibacterial agents.

The present invention is a foam composition in which the antibacterial composition is formed into a foam, and includes a step of forming the antibacterial composition into a foam.
The step of forming in a foam shape is preferably performed using a container formed in a foam shape, but any container may be used as long as it can form a foam shape.

(Antimicrobial composition)
The antibacterial composition of the present invention is
(A) Chitosan (B) quaternary ammonium salt (C) contains alcohols.

  Chitosan is obtained by crushing crab, shrimp shells, insect shells and other chitinous sources, treating with dilute hydrochloric acid to remove calcium carbonate, and treating with alkaline concentrated solution to remove proteins and other contaminants. It is a basic polysaccharide composed of glucosamine, which is a white amorphous powder obtained by deacetylating chitin obtained under high temperature with high concentration alkali. Chitosan is a biopolymer itself, so it does not show any oral toxicity and has no fear of irritating the skin.

  The chitosan used in the present invention has a weight average molecular weight of several thousands to several hundreds of thousands, but a low molecular weight is desirable from the viewpoint of bactericidal effect. Further, the degree of deacetylation is preferably 50% or more and 80% or more in consideration of water solubility and bacteriostatic effect.

And since free chitosan itself is not soluble in water, it may be used as a chitosan salt which is treated with an inorganic acid or an organic acid and is soluble in water, or an inorganic acid such as hydrochloric acid or phosphoric acid, acetic acid, It may be dissolved in an organic acid such as lactic acid, citric acid or gluconic acid. Preferably acetic acid is used.
Although there is no restriction | limiting in particular in content of chitosan, 0.01-5 mass% is preferable.

The quaternary ammonium salts of the present invention generally have a strong bacteriostatic action against Gram-positive bacteria, etc., are water-soluble and non-corrosive, are colorless and odorless at normal concentrations, and have low toxicity. It has been. Examples of the quaternary ammonium salt used in the present invention include benzalkonium chloride, benzethonium chloride, cetylpyridinium chloride, dimethylammonium chloride, tetradecyldimethylbenzylammonium chloride, and the like. It is particularly desirable in terms of effect.
The content of the quaternary ammonium salt is preferably 0.001 to 0.10% by mass, and more preferably 0.009 to 0.05% by mass. If it is less than 0.001% by mass, an antibacterial effect cannot be expected.

Examples of alcohols include ethanol, isopropanol, octaacetylated sucrose modified ethanol and the like.
The alcohol content is preferably 10 to 30% by mass, more preferably 15 to 25% by mass, and still more preferably 18 to 22% by mass.
As the solvent, water is usually used.

  If necessary, water retaining agents such as glycerin, propylene glycol, butylene glycol, hydroxyethyl cellulose, castor oil, sodium hyaluronate, sodium picolidone carboxylate, vegetable gum (such as gum arabic), surfactants, fragrances , Deodorants, pH adjusters, and other additives can be used in combination.

(Container that forms foam)
The container to be formed in a foam shape may be a container having any shape, material, or form as long as it is foamed, but a part for storing an antibacterial composition, a discharge port for forming foam, It is better to have means for guiding the stored antibacterial composition to the outlet, and it may be an integrated container or a combination of parts having individual functions.
The part for storing the antibacterial composition may be integrated with the container formed in the foam shape, or may be a structure that can be separated independently. If it is the structure which can be isolate | separated, it will be easy to store the said antibacterial composition by isolate | separating, and the said antibacterial composition can be supplied to a container by replacing | exchanging the said storage part whole.
The discharge port for forming the foam may be fixed to the container formed in the foam shape or may have a structure capable of being separated. The discharge port efficiently mixes a liquid antibacterial composition and a gas such as air to form bubbles.
The means for guiding the stored antibacterial composition to the discharge port may be a device that manually guides, such as a trigger part of a trigger type spray, or may be guided by a pump driven by electricity or the like. Good. In the case of a pump driven by electricity or the like, the pump may be driven by pressing a switch, or may be driven when a hand is held up using an optical sensor or the like.

(Process of forming foam)
Since this invention can maintain a foam state for a long time, it may apply | coat and form a foam, and may apply | coat after creating a bubble previously. Therefore, the step of creating the foam cleaner of the present invention is not particularly limited as long as it is a method capable of forming a foam. For example, the container may be used to form foam, and the container such as a beaker may be antibacterial. The composition may be put in, and bubbles may be formed manually or electrically using a tool such as a whisk, or may be vibrated or shaken.

(Embodiment)
An appropriate amount of foam is formed on the toilet paper using a container formed into a foam filled with the product of the present invention. The appropriate amount of foam is adjusted according to the surface area to be antimicrobial. For example, the toilet paper on which the foam is formed is spread on the toilet seat surface. When the product of the present invention is used, since the foam state is maintained for a long time, the foam does not disappear during spreading, the resistance between the toilet seat and the toilet paper is small, and it is slippery and has an antibacterial composition in a wide range. Can be applied. In the case where the product of the present invention is not used, since it is liquid from the beginning or the foam disappears while spreading, it cannot be applied unless the toilet paper is strongly pressed against the toilet seat. However, if the toilet paper is pressed hard, the toilet paper will be torn. Therefore, it cannot be applied unless the product of the present invention is used, and torn toilet paper becomes extra waste. The antibacterial composition spread using the product of the present invention quickly defoams and can be antibacterial with the defoamed antibacterial composition.
Since the product of the present invention contains chitosan, an antibacterial coating film is formed on the applied toilet seat. Therefore, antibacterial properties can be maintained for a long time. On the other hand, when a liquid chitosan-containing composition is used, a uniform antibacterial coating film cannot be formed, and the antibacterial property is lowered. Since the product of the present invention can form a uniform antibacterial coating film, the content of the quaternary ammonium salt that is an antibacterial component can be reduced. For this reason, possibility that inflammation etc. will generate | occur | produce in skin by a quaternary ammonium salt can be suppressed to the minimum.

  Examples of the present invention are shown below, but the technical scope of the present invention is not limited thereto.

[Example 1]
Using the container described in Example 1 of Table 1 as a “foaming foam that can be sterilized for clean pets (manufactured by Lion Corporation)”, 0.9 g of a foam composition was prepared, and toilet paper was used. (Nepane Nepinepi Single (registered trademark), manufactured by Oji Napier Co., Ltd.) was applied to a 6 × 9 cm polypropylene plate. Thereafter, the coated plate was allowed to stand at room temperature for 24 hours to collect falling bacteria. The entire surface of the plate was wiped using a CR stamp (manufactured by Actec Co., Ltd.), and the sponge portion was pressed 10 times on the entire surface of the standard agar medium for general viable cell count (manufactured by Actect Co., Ltd.) and applied uniformly. The agar medium was cultured at 30 ° C. for 2 days, and the number of colonies was visually measured. The results are shown in Table 1.

[Comparative Example 1]
The composition described in Example 1 of Table 1 was applied to 0.9 g of toilet paper (Nepane Nepinepi Single (registered trademark), manufactured by Oji Napier Co., Ltd.) in the liquid state, and the same operation as in Example 1 was performed. It was. The results are shown in Table 1.

第１表の結果から、泡状組成物とすることにより、抗菌性被膜を形成しやすく、持続的に菌の増加を抑えられることが明らかになった。

From the results of Table 1, it was revealed that by using a foam composition, an antibacterial film can be easily formed and the increase in bacteria can be suppressed continuously.

[Example 2]
The composition described in Example 2 of Table 2 is “Clean wipe form for clean pet use (made by Lion Corporation)” and “Muse no touch foam hand soap (registered trademark, manufactured by Liquid Bengeiser Japan Co., Ltd.) ”Was used to prepare 0.9 g of a foamy composition, which was taken on toilet paper (Nepia Nepinepi Single (registered trademark, manufactured by Oji Napier Co., Ltd.)). The bubbles were observed visually, and the time until the bubbles disappeared was measured. The results are shown in Table 2.

[Comparative Examples 2-3]
Instead of the composition described in Example 2, the same evaluation as in Example 2 was performed on the composition described in Comparative Example 2 and Comparative Example 3. The results are shown in Table 2.

第２表の結果から、塩化ベンザルコニウムとキトサンの混合組成物を作ることにより、泡の形成において相乗効果が得られることが判明した。

From the results in Table 2, it was found that a synergistic effect was obtained in foam formation by making a mixed composition of benzalkonium chloride and chitosan.

[Examples 3 to 5]
Each of the compositions described in Examples 3 to 5 in Table 3 is “Clean wipeable foam for clean pet (manufactured by Lion Corporation)” and “Muse No Touch Foam Hand Soap (registered trademark, Liquid Bengeiser Japan). 0.9 g of a foamed composition was prepared using a container of “made by Co., Ltd.” and taken on toilet paper (Nepane Nepinepi Single (registered trademark), produced by Oji Napier Co., Ltd.). The bubbles were observed visually, and the time until the bubbles disappeared was measured. Moreover, the toilet paper which 0.9g of foamy compositions adhered by the same method wiped 60 cm width on a desk 3 times, and evaluated the subsequent toilet paper with the following guidelines. The results are shown in Table 3.

Evaluation of wiping test ○: When wiping, there is no tearing residue on the desk. Δ: When wiping, tearing residue is left on the desk.
×: Toilet paper tears when wiped

[Comparative Examples 4 to 5]
In place of the composition described in Example 3, the same evaluation as in Example 3 was performed on the compositions described in Comparative Examples 4 to 5. The results are shown in Table 3.

  From the results in Table 3, it was found that the use of a composition having an ethanol concentration of 30% by mass or less resulted in a longer foam duration, and that the use of a composition of 10% by mass or more caused less damage to the toilet paper. .

Claims (4)

A foamy antibacterial composition for toilets comprising the following (A), (B) and (C).
(A) Chitosan (B) 0.001 to 0.10 mass% quaternary ammonium salt (C) 10 to 30 mass% alcohol The foamy antibacterial composition for toilets according to claim 1, wherein the alcohol content is 15 to 25% by mass. The foamy antibacterial composition for toilets according to claim 1 or 2, wherein the quaternary ammonium salt is benzalkonium chloride. The foamed antibacterial composition for toilets according to any one of claims 1 to 3, wherein the alcohol is ethanol.