JP6091893B2 - 機能的に分化した体細胞の増強された自己再生を誘導するための方法 - Google Patents
機能的に分化した体細胞の増強された自己再生を誘導するための方法 Download PDFInfo
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- JP6091893B2 JP6091893B2 JP2012519002A JP2012519002A JP6091893B2 JP 6091893 B2 JP6091893 B2 JP 6091893B2 JP 2012519002 A JP2012519002 A JP 2012519002A JP 2012519002 A JP2012519002 A JP 2012519002A JP 6091893 B2 JP6091893 B2 JP 6091893B2
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- 0 Cc(cc(cc1)Nc2nc(-c3ccc[s]3)ccn2)c1C(N(*)*)=O Chemical compound Cc(cc(cc1)Nc2nc(-c3ccc[s]3)ccn2)c1C(N(*)*)=O 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/17—Monocytes; Macrophages
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4242—Transcription factors, e.g. SOX or c-MYC
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- A—HUMAN NECESSITIES
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
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- C12N2501/60—Transcription factors
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Physical Education & Sports Medicine (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09305661.2 | 2009-07-08 | ||
| EP09305661 | 2009-07-08 | ||
| PCT/EP2010/059843 WO2011003988A1 (en) | 2009-07-08 | 2010-07-08 | A method for inducing extended self-renewal of functionally differentiated somatic cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015195849A Division JP2016028592A (ja) | 2009-07-08 | 2015-10-01 | 機能的に分化した体細胞の増強された自己再生を誘導するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012532592A JP2012532592A (ja) | 2012-12-20 |
| JP2012532592A5 JP2012532592A5 (enExample) | 2013-06-27 |
| JP6091893B2 true JP6091893B2 (ja) | 2017-03-08 |
Family
ID=41128562
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012519002A Expired - Fee Related JP6091893B2 (ja) | 2009-07-08 | 2010-07-08 | 機能的に分化した体細胞の増強された自己再生を誘導するための方法 |
| JP2015195849A Pending JP2016028592A (ja) | 2009-07-08 | 2015-10-01 | 機能的に分化した体細胞の増強された自己再生を誘導するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015195849A Pending JP2016028592A (ja) | 2009-07-08 | 2015-10-01 | 機能的に分化した体細胞の増強された自己再生を誘導するための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9175265B2 (enExample) |
| EP (1) | EP2451836A1 (enExample) |
| JP (2) | JP6091893B2 (enExample) |
| KR (1) | KR20120060201A (enExample) |
| CA (1) | CA2765504A1 (enExample) |
| SG (1) | SG177552A1 (enExample) |
| WO (1) | WO2011003988A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5861191B2 (ja) * | 2010-09-30 | 2016-02-16 | 国立大学法人 熊本大学 | ミエロイド系血液細胞の製造方法 |
| WO2013134022A1 (en) * | 2012-03-05 | 2013-09-12 | Wake Forest University Health Sciences | Regeneration of inner ear cells |
| JP6486272B2 (ja) * | 2012-09-07 | 2019-03-20 | マサチューセッツ・アイ・アンド・イア・インファーマリー | 有毛細胞および/または支持細胞再生のための方法および組成物 |
| WO2015077498A1 (en) * | 2013-11-20 | 2015-05-28 | The University Of North Carolina At Chapel Hill | Methods and compositions for treating disorders of the eye |
| KR102013060B1 (ko) * | 2018-01-29 | 2019-08-21 | 공주대학교 산학협력단 | Klf-4를 이용하는 연골세포 분화 촉진 방법 |
| JPWO2024034656A1 (enExample) * | 2022-08-09 | 2024-02-15 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE318818T1 (de) | 1998-06-16 | 2006-03-15 | Us Gov Health & Human Serv | Annellierte azepinone als inhibitoren cyclin- abhängiger kinasen |
| CA2543942A1 (en) | 2003-10-28 | 2005-05-12 | The Rockefeller University | Indirubin-type compounds, compositions, and methods for their use |
| CA2633069A1 (en) | 2005-12-23 | 2007-09-07 | Centre National De La Recherche Scientifique (Cnrs) | New 3'-, 7-substituted indirubins and their applications |
| EP1944361A1 (en) | 2007-01-11 | 2008-07-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A method for expanding monocytes |
| US20120282229A1 (en) * | 2007-08-01 | 2012-11-08 | Christian Kannemeier | Non-viral delivery of transcription factors that reprogram human somatic cells into a stem cell-like state |
| EP3078738B1 (en) | 2007-08-31 | 2020-05-20 | Whitehead Institute for Biomedical Research | Wnt pathway stimulation in reprogramming somatic cells |
| ATE529402T1 (de) | 2008-08-01 | 2011-11-15 | Centre Nat Rech Scient | 3',6-substituierte indirubine und ihre biologischen anwendungen |
| WO2010056907A2 (en) | 2008-11-12 | 2010-05-20 | The Scripps Research Institute | Compounds that induce pancreatic beta-cell expansion |
-
2010
- 2010-07-08 US US13/382,724 patent/US9175265B2/en not_active Expired - Fee Related
- 2010-07-08 CA CA2765504A patent/CA2765504A1/en not_active Abandoned
- 2010-07-08 EP EP10734946A patent/EP2451836A1/en not_active Withdrawn
- 2010-07-08 WO PCT/EP2010/059843 patent/WO2011003988A1/en not_active Ceased
- 2010-07-08 JP JP2012519002A patent/JP6091893B2/ja not_active Expired - Fee Related
- 2010-07-08 KR KR1020127003421A patent/KR20120060201A/ko not_active Abandoned
- 2010-07-08 SG SG2012001152A patent/SG177552A1/en unknown
-
2015
- 2015-10-01 JP JP2015195849A patent/JP2016028592A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| SG177552A1 (en) | 2012-03-29 |
| EP2451836A1 (en) | 2012-05-16 |
| US20120156179A1 (en) | 2012-06-21 |
| KR20120060201A (ko) | 2012-06-11 |
| CA2765504A1 (en) | 2011-01-13 |
| JP2016028592A (ja) | 2016-03-03 |
| US9175265B2 (en) | 2015-11-03 |
| JP2012532592A (ja) | 2012-12-20 |
| WO2011003988A1 (en) | 2011-01-13 |
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