JP6091214B2 - ポリ−グリセロールリン酸をベースにした抗グラム陽性細菌ワクチン - Google Patents

ポリ−グリセロールリン酸をベースにした抗グラム陽性細菌ワクチン Download PDF

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JP6091214B2
JP6091214B2 JP2012539057A JP2012539057A JP6091214B2 JP 6091214 B2 JP6091214 B2 JP 6091214B2 JP 2012539057 A JP2012539057 A JP 2012539057A JP 2012539057 A JP2012539057 A JP 2012539057A JP 6091214 B2 JP6091214 B2 JP 6091214B2
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pgp
group
cell
antigen
synthetic
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JP2013510882A (ja
JP2013510882A5 (enExample
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エム.スナッパー クリフォード
エム.スナッパー クリフォード
リーズ アンドリュー
リーズ アンドリュー
ジェイ.モンド ジェイムズ
ジェイ.モンド ジェイムズ
シュワルツ デイビッド
シュワルツ デイビッド
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ザ ヘンリー エム.ジャクソン ファウンデイション フォー ザ アドバンスメント オブ ミリタリー メディスン,インコーポレイティド
ザ ヘンリー エム.ジャクソン ファウンデイション フォー ザ アドバンスメント オブ ミリタリー メディスン,インコーポレイティド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/085Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55561CpG containing adjuvants; Oligonucleotide containing adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012539057A 2009-11-16 2010-11-15 ポリ−グリセロールリン酸をベースにした抗グラム陽性細菌ワクチン Expired - Fee Related JP6091214B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26157209P 2009-11-16 2009-11-16
US61/261,572 2009-11-16
PCT/US2010/056742 WO2011060379A2 (en) 2009-11-16 2010-11-15 (poly)-glycerolphosphate-based anti-gram positive bacterial vaccine

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JP2013510882A JP2013510882A (ja) 2013-03-28
JP2013510882A5 JP2013510882A5 (enExample) 2013-12-05
JP6091214B2 true JP6091214B2 (ja) 2017-03-08

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JP2012539057A Expired - Fee Related JP6091214B2 (ja) 2009-11-16 2010-11-15 ポリ−グリセロールリン酸をベースにした抗グラム陽性細菌ワクチン

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US (1) US20130052204A1 (enExample)
EP (1) EP2501403A4 (enExample)
JP (1) JP6091214B2 (enExample)
AU (2) AU2010320031B2 (enExample)
CA (1) CA2781049A1 (enExample)
WO (1) WO2011060379A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3120140B1 (en) * 2014-03-21 2018-10-31 Biotage AB Method and apparatus for the equilibration of a packed chromatography column
US10781175B2 (en) 2016-07-15 2020-09-22 Am Chemicals Llc Solid supports and phosphoramidite building blocks for oligonucleotide conjugates
WO2025166099A1 (en) * 2024-02-02 2025-08-07 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Fire-retardant wood and wood composites, and compositions useful for making same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9202219D0 (en) * 1992-02-03 1992-03-18 Connaught Lab A synthetic heamophilus influenzae conjugate vaccine
GB9808932D0 (en) * 1998-04-27 1998-06-24 Chiron Spa Polyepitope carrier protein
GB9811347D0 (en) * 1998-05-28 1998-07-22 Oxoid Ltd Improvements in or relating diagnosis and treatment of bacterial infections
US6800728B2 (en) * 2000-03-22 2004-10-05 Solulink Biosciences, Inc. Hydrazine-based and carbonyl-based bifunctional crosslinking reagents
AU2004299501B2 (en) * 2003-12-17 2010-12-23 Wyeth Llc Immunogenic peptide carrier conjugates and methods of producing same
WO2005072778A2 (en) * 2004-01-29 2005-08-11 Biosynexus, Inc. Use of amino-oxy functional groups in the preparation of vaccines conjugates
ES2730275T3 (es) * 2004-09-22 2019-11-11 Glaxosmithkline Biologicals Sa Composición inmunógena para uso en vacunación contra estafilococos
US7754225B2 (en) * 2006-07-20 2010-07-13 Glaxosmithkline Biologicals S.A. Method of protecting against staphylococcal infection

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Publication number Publication date
EP2501403A4 (en) 2013-11-13
CA2781049A1 (en) 2011-05-19
JP2013510882A (ja) 2013-03-28
WO2011060379A2 (en) 2011-05-19
WO2011060379A3 (en) 2011-08-04
AU2010320031B2 (en) 2015-07-16
EP2501403A2 (en) 2012-09-26
AU2010320031A1 (en) 2012-06-14
US20130052204A1 (en) 2013-02-28
AU2015238927A1 (en) 2015-10-29

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