JP6088425B2 - チトクロームｐ４５０阻害剤およびその使用 - Google Patents

チトクロームｐ４５０阻害剤およびその使用 Download PDF

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JP6088425B2
JP6088425B2 JP2013513284A JP2013513284A JP6088425B2 JP 6088425 B2 JP6088425 B2 JP 6088425B2 JP 2013513284 A JP2013513284 A JP 2013513284A JP 2013513284 A JP2013513284 A JP 2013513284A JP 6088425 B2 JP6088425 B2 JP 6088425B2
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alkyl
alkenyl
alkynyl
halo
imidazol
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JP2013527238A5 (https=
JP2013527238A (ja
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パニッカー，バイジョイ
オエレン，ラムベルタス．，ジェイ．ダブリュー．エム．
タラント，ジェイムス，ジー．
リム，ドン，スン
シュウ，シャオカン
ジュン，デウーン
ケイ． ミシュラ，ラマ，
ケイ． ミシュラ，ラマ，
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アンジオン バイオメディカ コーポレーション
アンジオン バイオメディカ コーポレーション
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Veterinary Medicine (AREA)
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  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Vascular Medicine (AREA)
  • Cardiology (AREA)
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  • Pain & Pain Management (AREA)
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  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
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  • Immunology (AREA)
JP2013513284A 2010-06-01 2011-06-01 チトクロームｐ４５０阻害剤およびその使用 Expired - Fee Related JP6088425B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39669610P 2010-06-01 2010-06-01
US61/396,696 2010-06-01
US201061460243P 2010-12-29 2010-12-29
US61/460,243 2010-12-29
PCT/US2011/038695 WO2011153192A2 (en) 2010-06-01 2011-06-01 Cytochrome p450 inhibitors and uses thereof

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JP2013527238A JP2013527238A (ja) 2013-06-27
JP2013527238A5 JP2013527238A5 (https=) 2014-08-07
JP6088425B2 true JP6088425B2 (ja) 2017-03-01

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Country Link
US (3) US8513291B2 (https=)
EP (1) EP2576544A4 (https=)
JP (1) JP6088425B2 (https=)
CN (1) CN102985420B (https=)
AU (1) AU2011261586B2 (https=)
CA (1) CA2800664C (https=)
IL (1) IL223056A (https=)
WO (1) WO2011153192A2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10414760B2 (en) 2016-11-29 2019-09-17 Angion Biomedica Corp. Cytochrome P450 inhibitors and uses thereof
US9199975B2 (en) 2011-09-30 2015-12-01 Asana Biosciences, Llc Biaryl imidazole derivatives for regulating CYP17
US8809372B2 (en) 2011-09-30 2014-08-19 Asana Biosciences, Llc Pyridine derivatives
EP2760854B1 (en) * 2011-09-30 2017-08-30 Asana BioSciences, LLC Imidazole derivatives as cyp17 inhibitors for the treatment of cancer
RS54936B1 (sr) 2011-10-14 2016-11-30 Ambit Biosciences Corp Heterociklična jedinjenja i njihova upotreba kao modulatora receptora tirozin kinaza tipa iii
WO2014015137A2 (en) * 2012-07-18 2014-01-23 Angion Biomedica Corp. Compositions and methods for treating dysproliferative diseases
JO3225B1 (ar) * 2012-11-27 2018-03-08 Lilly Co Eli 6-((s)-1-{1-[5-(2-هيدروكسي-إيثوكسي)-بيريدين-2-يل]-1h-بيرازول-3-يل}إيثيل)-3h-1 ، 3-بنزو ثيازول-2- أون باعتباره مضاد مستقبل ampa يعتمد على tarp- جاما 8
WO2014093960A1 (en) * 2012-12-16 2014-06-19 Angion Biomedica Corp. Compositions and methods for treating disease
CA2957785C (en) 2014-08-11 2023-01-03 Angion Biomedica Corporation Cytochrome p450 inhibitors and uses thereof
JP2018501279A (ja) 2014-12-31 2018-01-18 アンギオン バイオメディカ コーポレイション 疾患を治療するための方法及び薬剤
GB201602572D0 (en) * 2016-02-12 2016-03-30 Eriksson Leif And Strid Ake And Sirsjö Allan New compound and uses
JP7160487B2 (ja) 2017-05-04 2022-10-25 ビーエーエスエフ ソシエタス・ヨーロピア 植物病原菌を駆除するための置換５－（ハロアルキル）－５－ヒドロキシ－イソオキサゾール

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JP2003521543A (ja) * 2000-02-07 2003-07-15 アボット ゲーエムベーハー ウント カンパニー カーゲー ２−ベンゾチアゾリル尿素誘導体およびそのプロテインキナーゼ阻害剤としての使用
WO2002003912A2 (en) 2000-07-11 2002-01-17 University Of Maryland, Baltimore Novel c-4 substituted retinoids
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TWI286476B (en) * 2001-12-12 2007-09-11 Tibotec Pharm Ltd Combination of cytochrome P450 dependent protease inhibitors
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Publication number Publication date
IL223056A0 (en) 2013-02-03
JP2013527238A (ja) 2013-06-27
AU2011261586B2 (en) 2015-08-27
CN102985420A (zh) 2013-03-20
US8865752B2 (en) 2014-10-21
CN102985420B (zh) 2017-07-04
IL223056A (en) 2016-06-30
AU2011261586A1 (en) 2012-12-06
CA2800664C (en) 2019-09-24
US8513291B2 (en) 2013-08-20
WO2011153192A3 (en) 2012-04-19
WO2011153192A2 (en) 2011-12-08
EP2576544A2 (en) 2013-04-10
US20130102643A1 (en) 2013-04-25
US20140018401A1 (en) 2014-01-16
US20150158853A1 (en) 2015-06-11
EP2576544A4 (en) 2013-09-11
CA2800664A1 (en) 2011-12-08

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