JP6078076B2 - キナーゼ阻害剤多形体 - Google Patents

キナーゼ阻害剤多形体 Download PDF

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Publication number
JP6078076B2
JP6078076B2 JP2014541391A JP2014541391A JP6078076B2 JP 6078076 B2 JP6078076 B2 JP 6078076B2 JP 2014541391 A JP2014541391 A JP 2014541391A JP 2014541391 A JP2014541391 A JP 2014541391A JP 6078076 B2 JP6078076 B2 JP 6078076B2
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Japan
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acid
hcl
compound
cancer
pattern
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JP2014541391A
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English (en)
Japanese (ja)
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JP2014533285A (ja
JP2014533285A5 (enExample
Inventor
ピンダ レン，
ピンダ レン，
マイケル マーティン，
マイケル マーティン，
クリストファー ピーター ウォーラル，
クリストファー ピーター ウォーラル，
スサナ デル リオ ガンセド，
スサナ デル リオ ガンセド，
Original Assignee
インテリカイン， エルエルシー
インテリカイン， エルエルシー
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Publication of JP2014533285A5 publication Critical patent/JP2014533285A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2014541391A 2011-11-11 2012-11-12 キナーゼ阻害剤多形体 Active JP6078076B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161558962P 2011-11-11 2011-11-11
US61/558,962 2011-11-11
PCT/US2012/064729 WO2013071272A1 (en) 2011-11-11 2012-11-12 Kinase inhibitor polymorphs

Publications (3)

Publication Number Publication Date
JP2014533285A JP2014533285A (ja) 2014-12-11
JP2014533285A5 JP2014533285A5 (enExample) 2015-12-10
JP6078076B2 true JP6078076B2 (ja) 2017-02-08

Family

ID=48290672

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014541391A Active JP6078076B2 (ja) 2011-11-11 2012-11-12 キナーゼ阻害剤多形体

Country Status (5)

Country Link
US (1) US9403820B2 (enExample)
EP (1) EP2776428A4 (enExample)
JP (1) JP6078076B2 (enExample)
HK (1) HK1201271A1 (enExample)
WO (1) WO2013071272A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05007322A (es) 2003-01-06 2006-02-17 Angiochem Inc Aprotinina y analogos como portadores a traves de la barrera sangre-cerebro.
US9365634B2 (en) 2007-05-29 2016-06-14 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
MX355683B (es) 2008-04-18 2018-04-26 Angiochem Inc Composiciones farmacéuticas de paclitaxel, análogos de paclitaxel o conjugados de paclitaxel, y métodos relacionados de preparación y uso.
RU2011118056A (ru) 2008-10-15 2012-11-27 Ангиокем Инк. Конъюгаты агонистов glp-1 и их применение
MX2011004019A (es) 2008-10-15 2011-06-24 Angiochem Inc Conjugados de etoposido y doxorubicina para entrega de farmacos.
CN102307904A (zh) 2008-12-05 2012-01-04 安吉奥开米公司 神经降压素或神经降压素类似物的缀合物及其用途
CN102300987A (zh) 2008-12-17 2011-12-28 安吉奥开米公司 膜型-1基质金属蛋白抑制剂及其用途
US9173891B2 (en) 2009-04-20 2015-11-03 Angiochem, Inc. Treatment of ovarian cancer using an anticancer agent conjugated to an angiopep-2 analog
CN102596993A (zh) 2009-07-02 2012-07-18 安吉奥开米公司 多聚体肽结合物以及其应用
EP2792360A1 (en) 2013-04-18 2014-10-22 IP Gesellschaft für Management mbH (1aR,12bS)-8-cyclohexyl-11-fluoro-N-((1-methylcyclopropyl)sulfonyl)-1a-((3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-1,1a,2,2b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide for use in treating HCV
CN105745207A (zh) * 2013-10-03 2016-07-06 千年药物公司 使用PI3Kα抑制剂的增强的治疗方案
DK3307326T3 (da) 2015-06-15 2020-10-19 Angiochem Inc Fremgangsmåder til behandling af leptomeningeal karcinomatose
JP2018039755A (ja) * 2016-09-08 2018-03-15 大塚化学株式会社 ナトリウム２α−メチル−２β−（１，２，３−トリアゾール−１−イル）−メチルペナム−３α−カルボン酸１，１−ジオキシド一水和物結晶の製造方法

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
EP0068378B1 (en) * 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
DE10050663A1 (de) * 2000-10-13 2002-04-18 Gruenenthal Gmbh Verwendung von substituierten Imidazo[1,2-a]pyridin-, -pyrimidin- und pyrazin-3-yl-amin-Derivaten zur Herstellung von Medikamenten zur NOS-Inhibierung
CA2528192A1 (en) * 2003-06-03 2005-02-24 Teva Pharmaceutical Industries Ltd Cristalline ziprasidone hcl and processes for preparation thereof
EP1591625A1 (en) * 2004-04-30 2005-11-02 ALSTOM Technology Ltd Gas turbine blade shroud
CN101277956A (zh) 2005-09-30 2008-10-01 阿斯利康(瑞典)有限公司 具有抗细胞增殖活性的咪唑并【1，2-a】吡啶
US8193182B2 (en) * 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
SG187426A1 (en) * 2008-01-04 2013-02-28 Intellikine Llc Certain chemical entities, compositions and methods
US8476282B2 (en) 2008-11-03 2013-07-02 Intellikine Llc Benzoxazole kinase inhibitors and methods of use
JP5819831B2 (ja) * 2009-08-17 2015-11-24 インテリカイン， エルエルシー 複素環式化合物およびそれらの使用

Also Published As

Publication number Publication date
JP2014533285A (ja) 2014-12-11
HK1201271A1 (en) 2015-08-28
US9403820B2 (en) 2016-08-02
WO2013071272A1 (en) 2013-05-16
US20150005301A1 (en) 2015-01-01
EP2776428A4 (en) 2015-04-22
EP2776428A1 (en) 2014-09-17

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