JP6014749B2 - 薬剤送達装置 - Google Patents
薬剤送達装置 Download PDFInfo
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- JP6014749B2 JP6014749B2 JP2015506179A JP2015506179A JP6014749B2 JP 6014749 B2 JP6014749 B2 JP 6014749B2 JP 2015506179 A JP2015506179 A JP 2015506179A JP 2015506179 A JP2015506179 A JP 2015506179A JP 6014749 B2 JP6014749 B2 JP 6014749B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
- A61M5/5086—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile for indicating if defective, used, tampered with or unsterile
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/31568—Means keeping track of the total dose administered, e.g. since the cartridge was inserted
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
- A61M5/3204—Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
- A61M5/508—Means for preventing re-use by disrupting the piston seal, e.g. by puncturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2006—Having specific accessories
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M2005/3142—Modular constructions, e.g. supplied in separate pieces to be assembled by end-user
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Description
予め充填された薬剤容器は、広範な薬剤送達装置において、および特に薬剤の自己投与のために用いられている。用いられる薬剤容器の多くは、送達前には薬剤送達装置の中に置かれている予め充填された容器である。薬剤送達装置を薬剤送達の準備が整った状態にするために、注射針などの薬剤送達部材が容器の近端に装着される。
本発明の目的は、以上言及したような欠点を修正することである。
本願では、「遠位部/端」という用語を用いる場合、これは、装置の使用の際に患者の薬剤送達部位から最も遠く離れて位置する装置の部分/端またはその部材の部分/端を指す。対応して、「近位部/端」という用語を用いる場合、これは、装置の使用の際に患者の薬剤送達部位の最も近くに位置する装置の部分/端またはその部材の部分/端を指す。
−可動プランジャ11、首部分18、および送達部材ユニット22を備える薬剤容器12と、
−近位開放端13および対向する遠位開放端15を有する、長手方向軸Aに沿って長手方向に延在する筐体10と、
−筐体の遠端に配置され、ある用量の薬剤を送達するために可動プランジャに力を加えるように構成される駆動ユニット14と、を備える。
Claims (13)
- 近端および対向する遠端を有する薬剤送達装置であって、
可動プランジャ(11)、首部分(18)、および送達部材ユニット(22)を備える薬剤容器(12)と、
近位開放端(13)および対向する遠位開放端(15)を有する、長手方向軸(A)に沿って長手方向に延在する筐体(10)と、
筐体の遠端に配置され、可動プランジャに力を加えるように構成される駆動ユニット(14)と、
容器ユニットを形成する前記薬剤容器の首部分に装着できるように、長手方向に延在するスリット/間隙(34;134)を備えるC字状の管状体(16;160)とを備え、
前記C字状の管状体は、薬剤容器が前記C字状の管状体に装着された後は前記薬剤容器の首部分および前記送達部材ユニットとの相互作用によって前記C字状の管状体に対して前記薬剤容器が動かないように構成される内側支持手段と、容器ユニットが遠位開放端を通して前記筐体内に配置された後は前記C字状の管状体が筐体に対して動かないようにされるように、筐体の対応の支持手段と相互作用するように構成される外側支持手段とをさらに備えることを特徴とする、薬剤送達装置。 - 前記送達部材ユニット(22)は、装着部(24)と、装着部に取外し可能に接続される閉止キャップ/シールド(26)とを備える、請求項1に記載の薬剤送達装置。
- 前記内側支持手段は、装着部の外面上の少なくとも1つの長手方向に延在する窪み(28)と相互作用するように構成される、C字状の管状体の内周面上の少なくとも1つの長手方向に延在する径方向内向きの桟(44)を備え、これにより前記薬剤容器はC字状の管状体に対して回転しないようにされる、請求項2に記載の薬剤送達装置。
- 前記内側支持手段は、前記薬剤容器(12)の首部分および装着部(24)の遠位環状表面(23)と相互作用するように構成される、C字状の管状体の内周面上の連続した環状の径方向内向きの桟(36)または別々の環状の径方向内向きの桟をさらに備え、これにより前記薬剤容器はC字状の管状体に対して長手方向に動かないようにされる、請求項3に記載の薬剤送達装置。
- 前記外側支持手段は、装置の遠端に向いた、筐体の内周面上に配置される対応の連続した環状表面または別々の環状表面(52)と相互作用するように構成される、装置の近端に向いた、C字状の管状体の外周面上の連続した環状表面(48)または別々の環状表面を備え、これにより容器ユニットが筐体の遠位開放端を通って前記筐体内に配置された後は前記C字状の管状体は筐体の近位開放端を通らないようにされる、請求項1から4のいずれか1項に記載の薬剤送達装置。
- 前記外側支持手段は、長手方向に延在するスリット/間隙(34)を形成する第1および第2の対向する横方向端縁(30,31)をさらに備え、前記横方向端縁は、筐体の内周面上に配置される、長手方向に延在する径方向内向きの桟またはリブ(54)と相互作用するように構成され、これにより容器ユニットは筐体に対して回転しないようにされる、請求項5に記載の薬剤送達装置。
- 前記外側支持手段は、前記筐体(100)の内面上の多数の着座部(162)と相互作用するように構成される、前記C字状の管状体(160)の外面上の多数の外向きに延在する突起(148)を備える、請求項1から4のいずれか1項に記載の薬剤送達装置。
- 前記C字状の管状体(160)は、突起(148)と着座部(162)との間の相互作用を容易にするための屈曲部材(134,142)を有して配置される、請求項7に記載の薬剤送達装置。
- 前記突起(148)は、突起(148)と着座部(162)との間の相互作用を容易にするように傾斜面(150)を有して配置される、請求項8に記載の薬剤送達装置。
- 前記C字状の管状体(160)は、ある距離だけ遠位方向に延在して薬剤容器(12)の少なくとも一部を取囲み、前記突起(148)は前記C字状の管状体(160)の遠端に配置される、請求項7から9のいずれかに記載の薬剤送達装置。
- 前記送達部材ユニット(22)はTELCユニットである、請求項2から10のいずれか1項に記載の薬剤送達装置。
- 装置は、注射装置である、請求項1から11のいずれか1項に記載の薬剤送達装置。
- 装置は、自己注射装置である、請求項1から12のいずれか1項に記載の薬剤送達装置。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261625409P | 2012-04-17 | 2012-04-17 | |
US61/625,409 | 2012-04-17 | ||
SE1250381 | 2012-04-17 | ||
SE1250381-9 | 2012-04-17 | ||
PCT/EP2013/057390 WO2013156346A2 (en) | 2012-04-17 | 2013-04-09 | Medicament delivery device |
Publications (2)
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JP2015516849A JP2015516849A (ja) | 2015-06-18 |
JP6014749B2 true JP6014749B2 (ja) | 2016-10-25 |
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JP2015506179A Active JP6014749B2 (ja) | 2012-04-17 | 2013-04-09 | 薬剤送達装置 |
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US (2) | US9302059B2 (ja) |
EP (1) | EP2887983B1 (ja) |
JP (1) | JP6014749B2 (ja) |
KR (1) | KR101676552B1 (ja) |
CN (1) | CN104321102B (ja) |
AU (1) | AU2013248413B2 (ja) |
CA (1) | CA2870471C (ja) |
DK (1) | DK2887983T3 (ja) |
ES (1) | ES2623168T3 (ja) |
IL (1) | IL235163B (ja) |
RU (1) | RU2606492C2 (ja) |
TW (1) | TWI556847B (ja) |
WO (1) | WO2013156346A2 (ja) |
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WO2013156346A2 (en) * | 2012-04-17 | 2013-10-24 | Carebay Europe Ltd | Medicament delivery device |
CN110013585B (zh) * | 2013-11-28 | 2022-08-23 | 卡贝欧洲有限公司 | 药剂输送装置的壳体 |
US10363377B2 (en) | 2014-12-03 | 2019-07-30 | Eli Lilly And Company | Needle shield puller cap assembly |
US10898646B2 (en) * | 2016-04-29 | 2021-01-26 | Shl Medical Ag | Container holder assembly |
CN109310826B (zh) * | 2016-07-06 | 2021-08-31 | 艾斯曲尔医疗公司 | 用于药物容器的装置 |
JP6752960B2 (ja) * | 2016-07-22 | 2020-09-09 | エス・ハー・エル・メディカル・アクチェンゲゼルシャフトShl Medical Ag | 薬剤送達装置のための薬剤容器ホルダおよび薬剤送達装置の組立方法 |
US10583255B2 (en) | 2016-07-27 | 2020-03-10 | Shl Medical Ag | Medicament container assembly for a medicament delivery device |
WO2018206583A1 (en) * | 2017-05-09 | 2018-11-15 | Shl Medical Ag | Transport lock assembly, and a medicament delivery device comprising the transport lock assembly |
CN107137158B (zh) * | 2017-06-06 | 2018-09-11 | 浙江大学 | 一种电动有针注射器的可拆卸装置 |
EP3706841B1 (en) | 2017-11-07 | 2023-11-22 | SHL Medical AG | Needle shield remover and a medicament delivery device comprising the needle shield remover |
US20200360236A1 (en) * | 2018-02-02 | 2020-11-19 | . | Syringe assembly |
GB2577558B (en) * | 2018-09-28 | 2021-08-18 | Owen Mumford Ltd | Substance delivery devices |
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DK228290D0 (da) * | 1990-09-21 | 1990-09-21 | Novo Nordisk As | An injektion unit |
US20030078195A1 (en) * | 2001-08-27 | 2003-04-24 | Kristensen Lars Thougaard | Cartridge and medical delivery system accommodating such cartridge |
ATE497397T1 (de) * | 2006-07-15 | 2011-02-15 | Novo Nordisk As | Medizinisches abgabeystem mit drehbarem verschlüsselungselement |
EP2121086B2 (en) * | 2006-11-21 | 2015-12-23 | Novo Nordisk A/S | Medical delivery system comprising locking ring with l-shaped grooves |
US8740857B2 (en) * | 2006-12-21 | 2014-06-03 | Novo Nordisk A/S | Syringe device |
US8888713B2 (en) * | 2007-03-07 | 2014-11-18 | Becton, Dickinson And Company | Safety blood collection assembly with indicator |
GB2463071A (en) * | 2008-09-02 | 2010-03-03 | Owen Mumford Ltd | Auto-injector syringe with safety shield |
GB201001506D0 (en) | 2010-02-01 | 2010-03-17 | Liversidge Barry P | Medical needle safety device |
US9061104B2 (en) * | 2010-03-09 | 2015-06-23 | Shl Group Ab | Medicament injection device |
CA2795844A1 (en) * | 2010-04-09 | 2011-10-13 | Sanofi-Aventis Deutschland Gmbh | Coded drug reservoir connection element with hinged flange |
WO2012020083A1 (en) * | 2010-08-13 | 2012-02-16 | Sanofi-Aventis Deutschland Gmbh | Coded drug reservoir connection element with hinge |
WO2013156346A2 (en) * | 2012-04-17 | 2013-10-24 | Carebay Europe Ltd | Medicament delivery device |
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- 2013-04-09 WO PCT/EP2013/057390 patent/WO2013156346A2/en active Application Filing
- 2013-04-09 CA CA2870471A patent/CA2870471C/en active Active
- 2013-04-09 CN CN201380027673.XA patent/CN104321102B/zh active Active
- 2013-04-09 ES ES13720265.1T patent/ES2623168T3/es active Active
- 2013-04-09 RU RU2014145849A patent/RU2606492C2/ru active
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- 2013-04-09 US US14/394,993 patent/US9302059B2/en active Active
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Also Published As
Publication number | Publication date |
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US20160101235A1 (en) | 2016-04-14 |
RU2606492C2 (ru) | 2017-01-10 |
AU2013248413A1 (en) | 2014-11-27 |
AU2013248413B2 (en) | 2016-01-14 |
DK2887983T3 (en) | 2017-04-10 |
WO2013156346A9 (en) | 2014-06-05 |
KR101676552B1 (ko) | 2016-11-15 |
US20150112259A1 (en) | 2015-04-23 |
WO2013156346A2 (en) | 2013-10-24 |
CN104321102B (zh) | 2016-10-19 |
WO2013156346A3 (en) | 2014-05-08 |
TW201402167A (zh) | 2014-01-16 |
US9884153B2 (en) | 2018-02-06 |
RU2014145849A (ru) | 2016-06-10 |
US9302059B2 (en) | 2016-04-05 |
TWI556847B (zh) | 2016-11-11 |
KR20150008116A (ko) | 2015-01-21 |
EP2887983A2 (en) | 2015-07-01 |
JP2015516849A (ja) | 2015-06-18 |
ES2623168T3 (es) | 2017-07-10 |
CA2870471A1 (en) | 2013-10-24 |
EP2887983B1 (en) | 2017-02-01 |
CA2870471C (en) | 2016-11-08 |
CN104321102A (zh) | 2015-01-28 |
IL235163B (en) | 2018-08-30 |
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