JP5943996B2 - 腫瘍溶解性強化Ｂ型ヒトアデノウイルスＡｄ１１突然変異体の構築とその応用 - Google Patents

腫瘍溶解性強化Ｂ型ヒトアデノウイルスＡｄ１１突然変異体の構築とその応用 Download PDF

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JP5943996B2
JP5943996B2 JP2014513035A JP2014513035A JP5943996B2 JP 5943996 B2 JP5943996 B2 JP 5943996B2 JP 2014513035 A JP2014513035 A JP 2014513035A JP 2014513035 A JP2014513035 A JP 2014513035A JP 5943996 B2 JP5943996 B2 JP 5943996B2
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gene expression
expression cassette
gfp
tumor
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王▲尭▼河
姜国忠
黄▲漢▼熙
曹▲風▼雨
莱蒙・尼克
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北京▲錘▼特生物科技有限公司
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    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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JP2014513035A 2011-05-31 2012-02-29 腫瘍溶解性強化Ｂ型ヒトアデノウイルスＡｄ１１突然変異体の構築とその応用 Active JP5943996B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201110143385.3 2011-05-31
CN2011101433853A CN102260712B (zh) 2011-05-31 2011-05-31 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用
PCT/CN2012/071757 WO2012163119A1 (zh) 2011-05-31 2012-02-29 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用

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JP2014523236A JP2014523236A (ja) 2014-09-11
JP2014523236A5 JP2014523236A5 (OSRAM) 2015-08-20
JP5943996B2 true JP5943996B2 (ja) 2016-07-05

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US (3) US9315827B2 (OSRAM)
EP (1) EP2716764B1 (OSRAM)
JP (1) JP5943996B2 (OSRAM)
CN (1) CN102260712B (OSRAM)
WO (1) WO2012163119A1 (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102260712B (zh) * 2011-05-31 2013-10-02 北京锤特生物科技有限公司 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用
SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
PL3198009T3 (pl) 2014-09-24 2022-01-24 Salk Institute For Biological Studies Onkolityczne wirusy nowotworowe i sposoby zastosowania
JP7054527B2 (ja) 2016-02-23 2022-04-14 ソーク インスティテュート フォー バイオロジカル スタディーズ アデノウイルスの複製動態を測定するための高スループットアッセイ
JP7015551B2 (ja) 2016-02-23 2022-02-15 ソーク インスティテュート フォー バイオロジカル スタディーズ ウイルス動態への影響を最小限にするための治療用アデノウイルスにおける外因性遺伝子発現
CN106591368A (zh) * 2016-10-12 2017-04-26 郑州大学 携带il‑15r/il‑15融合基因的b亚群腺病毒11载体及其构建和用途
WO2018111767A1 (en) 2016-12-12 2018-06-21 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
CN110093323B (zh) * 2018-01-31 2024-01-30 上海元宋生物技术有限公司 重组溶瘤腺病毒OncoAd-P28GANK-E1A-△E1B及其构建方法和应用
JP7430395B2 (ja) 2018-04-09 2024-02-13 ソーク インスティテュート フォー バイオロジカル スタディーズ 複製特質が増強された腫瘍溶解性アデノウイルス組成物

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Publication number Priority date Publication date Assignee Title
ES2372823T3 (es) * 1999-05-17 2012-01-26 Crucell Holland B.V. Adenovirus recombinante del serotipo ad11.
BRPI0516048A (pt) * 2004-10-13 2008-08-19 Crucell Holland B V E Beth Isr batelada de um adenovìrus recombinante defectivo em replicação baseado em um sorotipo do subgrupo c
NZ581306A (en) * 2004-11-16 2011-03-31 Crucell Holland Bv Multivalent vaccines comprising recombinant viral vectors
CA2679410C (en) * 2007-03-02 2017-01-17 Glaxosmithkline Biologicals S.A. Novel method and compositions
CN102260712B (zh) * 2011-05-31 2013-10-02 北京锤特生物科技有限公司 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用

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Publication number Publication date
US20140088180A1 (en) 2014-03-27
EP2716764A1 (en) 2014-04-09
WO2012163119A1 (zh) 2012-12-06
CN102260712A (zh) 2011-11-30
CN102260712B (zh) 2013-10-02
US9315827B2 (en) 2016-04-19
US20180187214A1 (en) 2018-07-05
EP2716764A4 (en) 2015-01-14
EP2716764B1 (en) 2019-05-01
US9932606B2 (en) 2018-04-03
JP2014523236A (ja) 2014-09-11
US10294493B2 (en) 2019-05-21
US20160222413A1 (en) 2016-08-04

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