JP5939746B2 - Optical tomography probe - Google Patents

Description

  The present invention relates to an optical tomographic probe, and more particularly to an optical tomographic probe used in an optical tomographic imaging apparatus that generates an optical tomographic image by optical coherence tomography (OCT) measurement.

  In recent years, an optical tomographic imaging apparatus using an optical coherence tomography (OCT) measurement method using interference by low-coherence light, for example, as a method for acquiring a tomographic image without cutting a measurement target such as a biological tissue Development is ongoing (see, for example, Patent Document 1).

  According to this OCT measurement method, the low-coherence light emitted from the light source is divided into the measurement light and the reference light by the light dividing means, and the measurement light is irradiated onto the measurement object. Then, the return light from the measurement object is guided to the multiplexing means. On the other hand, the reference light is guided to the multiplexing means after passing through the reference optical path that matches the optical path length to the measurement target of the measurement light. The return light and the reference light guided to the multiplexing means are combined and interfered by the multiplexing means, the interference light is detected as an electrical signal, and a tomographic image of the measurement target in the depth direction is generated by the arithmetic processing unit. It has come to be.

  In such an optical tomographic imaging apparatus using an OCT measurement method, an optical tomographic probe (OCT) is used to irradiate measurement light on a measurement target at a desired measurement site of a subject and capture return light from the measurement target. Probe) is used.

  The OCT probe is covered with, for example, a flexible long cylindrical probe outer tube (sheath), for example, an optical fiber inserted along the axis of the sheath, and a tip portion of the optical fiber. Is provided with an optical system (light emitting means). The optical fiber of the OCT probe is optically connected to the OCT processor that is the main body of the optical tomographic imaging apparatus, and the measurement light emitted from the OCT processor is transmitted through the optical fiber in the OCT probe to transmit the optical fiber. After the light is emitted from the tip of the OCT probe in the longitudinal direction of the OCT probe, the measurement light is inclined by a predetermined angle with respect to the longitudinal axis of the OCT probe due to the deflection and focusing of the optical system (with respect to the longitudinal axis of the OCT probe). Thus, the light is condensed and irradiated in a substantially orthogonal direction (see, for example, Patent Documents 2 to 5).

  The optical system at the tip of the optical fiber is connected to, for example, an optical fiber, and radial scanning is performed to rotate the irradiation direction of measurement light in the circumferential direction by rotating the optical fiber within the sheath. As a result, the tomographic information of the measurement target in the cross section substantially orthogonal to the longitudinal axis of the OCT probe is acquired. Further, linear scanning is performed in which the irradiation position of the measurement light is moved in the longitudinal axis direction of the OCT probe by moving the optical fiber straight in the sheath, thereby acquiring the tomographic information of the measurement target in the cross section along the longitudinal axis. Has been done. Further, by performing these radial scanning and linear scanning in parallel, tomographic information (three-dimensional volume data) to be measured in a three-dimensional region around the longitudinal axis of the OCT probe is acquired.

  Patent Document 6 describes an ultrasonic endoscope apparatus that guides an endoscope insertion portion into a body cavity using an insertion assisting tool. According to this, the balloon which can be expanded / contracted is installed in two places, the front-end | tip part of an insertion auxiliary tool, and the front-end | tip part of an endoscope insertion part. Then, the endoscope insertion portion and the insertion assisting tool are inserted to the target site in the body cavity while using the two balloons with the endoscope insertion portion protruding forward from the distal end of the insertion assisting tool. After reaching the target site, these two balloons are expanded to form a sealed space in the body cavity, and water is injected into the sealed space to perform ultrasonic measurement.

JP-A-6-165784 JP 2010-43994 A JP 2010-46216 A JP 2010-14667 A JP 2006-95143 A JP 2005-261857 A

  By the way, in order to obtain good tomographic information of the region along the longitudinal axis direction of the inner wall of the lumen by inserting the OCT probe into a small-diameter lumen such as the biliary tract and the pancreatic duct, It is desired to stably fix the OCT probe to the inner wall surface in parallel to the longitudinal axis direction. For this purpose, it is conceivable to fix the OCT probe with balloons installed in two places as in Patent Document 6.

  However, Patent Document 6 does not consider the size of the balloons installed at two locations. Even if the OCT probe is simply fixed in the lumen by the balloons installed at two locations, the inner wall surface of the lumen. However, the OCT probe is not always fixed in parallel.

  Further, the rigidity of the OCT probe alone is low, and the outer diameter is particularly large when a balloon is installed on the OCT probe. Therefore, when an OCT probe is inserted into a thin lumen such as a biliary tract or a pancreatic duct, rigidity for pushing the OCT probe into the lumen is insufficient, and the OCT probe may be inserted into the lumen. There is a problem that becomes difficult.

  The present invention has been made in view of such circumstances, and can be reliably and stably fixed to the inner wall surface of the lumen, and can be fixed in a small diameter lumen such as a biliary tract or pancreatic duct. An object of the present invention is to provide an optical tomography probe that can be easily inserted into the probe.

In order to achieve the above object, the present invention provides a light guide means for guiding measurement light for acquiring optical tomographic information of a measurement target, and a light guide means provided at a tip of the light guide means and guided by the light guide means. A light emitting means for emitting the emitted measurement light toward the measurement object, a first outer tube that covers the outside of the light guide means, and at least the tip side is formed of a light-transmitting member; and the first 1st expansion / contraction means provided in the outer tube, a second outer tube provided to be able to advance and retract so as to cover the first outer tube, and an expansion / contraction provided in the second outer tube Possible second expansion / contraction means, the radius of the second expansion / contraction means when enlarged is substantially the same as the radius of expansion of the first expansion / contraction means, and the second expansion / contraction means of the second expansion / contraction means The position of the central axis of the second outer tube relative to the second expansion / contraction means during expansion in the radial direction When the said first position and the same der in the radial direction of the central axis of the mantle tube to said first scaling means at the time of expansion of the first scaling means is, the second and the first outer tube The outer tube is provided at a position eccentric from the central axis of the first expanding / contracting means and the second expanding / contracting device, respectively, and is a side surface of the first outer tube, A driving lumen is provided to drive the first expansion / contraction means in the direction in which the distance from the tube to the peripheral region of the first expansion / contraction means is the largest .

According to the present invention, the probe can be stably fixed in the lumen by pressing the first expansion / contraction means and the second expansion / contraction means against the inner wall surface of the lumen into which the optical tomographic probe is inserted. . Moreover, since the radius at the time of expansion of the 1st expansion / contraction means and the 2nd expansion / contraction means is the same, when those expansion / contraction means are pressed against the inner wall surface of the lumen, the lumen is corrected into a columnar shape. be able to. The positions of the central axes of the first outer tube and the second outer tube relative to each of the first expansion / contraction unit and the second expansion / contraction unit in the radial direction are the same. wall can be reliably arranged parallel to the probe relative to (the longitudinal axis of the lumen which is in a cylindrical shape), it is possible to prevent the scanning obliquely is performed. Further, since the first mantle tube is covered with the second mantle tube, the rigidity of the probe is enhanced, and the probe can be easily inserted into the small-diameter lumen.

  In the present invention, the first mantle tube and the second mantle tube are provided at positions eccentric from the central axes of the first expanding / contracting means and the second expanding / contracting means, respectively. And a driving lumen is provided for driving the first expansion / contraction means in a direction in which the distance from the first outer tube to the peripheral region of the first expansion / contraction means is the largest. Some embodiments are possible.

  According to the present invention, the greater the distance from the first outer tube to the peripheral region of the first expansion / contraction means, the less important the measurement object is. Therefore, the first expansion / contraction means is placed in that direction. By providing a lumen for driving, the influence of the lumen on the measurement is reduced.

  In the present invention, it is preferable that the second outer tube is provided with a housing portion that houses the first expansion / contraction means therein. According to the present invention, when the probe is inserted into the target lumen, the first expansion / contraction means is accommodated in the second outer tube so that only the second expansion / contraction means is externally provided. Thus, it is possible to reduce that the insertion of the probe into the lumen is hindered by the first expansion / contraction means.

  According to the present invention, the second outer tube is a lumen for sucking a space on the tip side of the second expansion / contraction means, and has an opening on the tip side of the second expansion / contraction means. Is preferably formed. According to the present invention, the probe is inserted into the target lumen, and the first expansion / contraction means of the first mantle tube is disposed in front of the second expansion / contraction means of the second mantle tube, so that the first and When the measurement is performed by expanding the second expansion / contraction means and pressing the first and second expansion / contraction means against the inner wall surface of the lumen, the space between the first expansion / contraction means and the second expansion / contraction means is increased. Aspiration can be performed, whereby measurement can be performed in a state where the inner wall of the lumen is adsorbed and fixed to the first outer tube.

  The present invention provides a lumen for injecting a contrast medium into the space on the distal end side of the second enlarging / contracting means in the second mantle tube, and opening to the distal end side of the second expanding / contracting means. It is preferable that the lumen | rumen which has is formed. According to the present invention, the probe is inserted into the target lumen, and the first expansion / contraction means of the first mantle tube is disposed in front of the second expansion / contraction means of the second mantle tube, so that the first and When the measurement is performed by enlarging the second expansion / contraction means and pressing the first and second expansion / contraction means against the inner wall of the lumen, a contrast is formed in the space between the first expansion / contraction means and the second expansion / contraction means. An agent can be injected, whereby an image highlighting the lumen in the measurement region between the first expansion / contraction means and the second expansion / contraction means can be taken.

  In the present invention, it is preferable that the first outer tube has a liquid-feeding lumen that opens to the proximal end side with respect to the first expansion / contraction means. According to the present invention, a desired liquid can be supplied between the first expansion / contraction means and the second expansion / contraction means through the lumen of the first outer tube.

  According to the present invention, the liquid supply lumen is provided on a side surface of the first outer tube, and is provided in a direction in which the distance from the first outer tube to the peripheral region of the first expansion / contraction means is the largest. Preferably it is. According to the present invention, it is considered that the greater the distance from the first outer tube to the peripheral region of the first expansion / contraction means, the lower the importance as a measurement object. It is intended to be provided.

  In the present invention, it is preferable that the second outer tube has higher rigidity than the first outer tube. Since the rigidity of the probe can be further increased by the second mantle tube, the probe can be easily inserted into the small-diameter lumen even when the expansion / contraction means is installed in the probe.

  According to the present invention, the optical tomography probe can be reliably and stably fixed in parallel to the inner wall surface of the lumen, and can be placed in a small-diameter lumen such as a biliary tract or pancreatic duct. Can also be inserted easily.

The block diagram which shows the whole structure of one Embodiment of the optical tomographic imaging apparatus in which the optical probe which concerns on this invention is used Side view showing the overall appearance of the OCT probe device Side sectional view of the OCT probe device cut along the longitudinal axis Explanatory drawing used for explanation when inserting probe insertion part into bile duct Explanatory drawing used for explanation when measuring by inserting the probe insertion part in the bile duct Side sectional view showing the state of the main components of the probe insertion portion when the probe is inserted to insert the probe insertion portion into a predetermined lumen Side sectional view showing the state of the main components of the probe insertion portion during measurement using the probe insertion portion inserted into the lumen The perspective view which showed the state at the time of measurement of a probe insertion part FIG. 4A is a front sectional view of the probe insertion portion cut at the position of the first balloon at the time of measurement, and FIG. 4B is a cross-sectional view of the probe insertion portion cut at the position of the second balloon at the time of measurement. Front sectional view 9A and 9B show a form of the probe insertion portion different from FIG. 9, in which FIG. 9A is a front cross-sectional view of the probe insertion portion at the time of measurement cut at the position of the first balloon, and FIG. Front sectional view of the probe insertion section cut at the position of the second balloon

  Hereinafter, the best mode for carrying out the optical tomography probe according to the present invention will be described.

  FIG. 1 is a block diagram showing the overall configuration of an embodiment of an optical tomographic imaging apparatus in which an optical probe according to the present invention is used.

  The optical tomographic imaging apparatus shown in the figure is an apparatus that acquires an optical tomographic image of a measurement object S by an optical coherence tomography (OCT) measurement method, and is inserted into a body cavity of a subject to be measured. (Measurement object S) is irradiated with measurement light L1, OCT probe device 10 that captures return light L3 (backscattered light) from measurement object S, measurement light L3 is generated and emitted to OCT probe device 10, and The OCT processor 12 that receives the return light L3 from the OCT probe apparatus 10 to acquire the tomographic information of the measurement object S and generates a tomographic image, and the monitor apparatus 14 that displays the tomographic image of the OCT processor 12, etc. Has been.

  The OCT processor 12 mainly includes a light source unit 20, optical fiber couplers 22 and 28, circulators 24 and 26, an interference light detection unit 50, a processing unit 54, a control operation unit 56, and the like.

  The light source unit 20 generates light for measuring OCT (for example, laser light having a wavelength of 1.3 μm or low coherence light). The light source unit 20a generates laser light or low coherence light La, and the light source 20a. The lens 20b which condenses the light La inject | emitted from is provided. The light La emitted from the light source unit 20 is guided to the optical fiber coupler 22 by the optical fiber FB4.

  The optical fiber coupler 22 is optically connected to the optical fibers FB3, FB4, and FB5, and the light La guided from the light source unit 20 to the optical fiber coupler 22 is referred to as the measurement light L1 by the optical fiber coupler 22. The measurement light L1 is split into light L2, and enters the optical fiber FB3 and guided to the circulator 24. The reference light L2 enters the optical fiber FB5 and is guided to the circulator 26.

  The circulator 24 is optically connected to the optical fiber FB3, the fixed side optical fiber FB2, the optical fibers FB3 and FB10, and the measurement light L1 guided from the optical fiber coupler 22 to the circulator 24 is fixed to the fixed side optical fiber FB2. And is guided to the optical rotary joint 60 of the OCT probe apparatus 10.

  The optical rotary joint 60 is optically connected to the fixed side optical fiber FB2 and the rotation side optical fiber FB1 of the OCT probe device 10. The optical rotary joint 60 rotates the rotation side optical fiber FB1 with respect to the fixed side optical fiber FB2. Are pivotally optically connected.

  The measurement light L1 guided from the circulator 24 to the optical rotary joint 60 enters the rotation-side optical fiber FB1, and is guided to the light emitting unit 62 (an optical lens 82 described later) provided at the tip of the optical fiber FB1. Is done. The measurement light L1 guided to the light emitting part 62 is emitted from the light emitting part 62 and irradiated to the measurement object S. The emission direction of the measurement light L1 from the light emission part 62 is substantially orthogonal to the direction inclined in the predetermined angle with respect to the longitudinal axis of the OCT probe device 10 (optical axis of the rotation side optical fiber FB1). Direction).

  Further, the return light L3 returned from the measurement target S by the backscattering (reflection) of the measurement light L1 irradiated to the measurement target S from the light emission unit 62 is incident on the rotation side optical fiber FB1 from the light emission unit 62, and the light It is guided to the rotary joint 60. The return light L3 guided to the optical rotary joint 60 enters the fixed optical fiber FB2 and is guided to the circulator 24. The return light L3 guided from the optical rotary joint 60 to the circulator 24 enters the optical fiber FB10 and is guided to the optical fiber coupler 28.

  On the other hand, the reference light L2 divided by the optical fiber coupler 22 and guided to the circulator 26 enters the optical fiber FB6 and is guided to the optical path length adjustment unit 30.

  The optical path length adjustment unit 30 adjusts the optical path length of the reference light L2 guided from the circulator 26, and includes a first optical lens 32a, a second optical lens 32b, a reflection mirror 32c, a base 34, and a mirror moving mechanism 36. have.

  The first optical lens 32a has the end of the optical fiber FB6 disposed at the focal position, and the reference light L2 emitted from the end of the optical fiber FB6 is converted into parallel light by the first optical lens 32a. The light is condensed by the second optical lens 32b and is incident on the reflection mirror 32c disposed at the focal position of the second optical lens 32b. The reference light L2 incident on the reflection mirror 32c is reflected by the reflection mirror 32c, converted into parallel light by the second optical lens 32b, and then condensed by the first optical lens 32a and is emitted from the end of the optical fiber FB6. The light enters the fiber FB 6 and is guided to the circulator 26.

  The second optical lens 32b and the reflection mirror 32c are fixed to the base 34, and the base 34 is moved by the mirror moving mechanism 36 in the optical axis direction (arrow A direction) of the first optical lens 32a and the second optical lens 32b. ) To move to. Thereby, the optical path length of the reference light L2 can be changed by changing the distance between the first optical lens 32a and the second optical lens 32b.

  The reference light L2 that has passed through the optical path length adjusting unit 30 and returned to the circulator 26 enters the optical fiber FB7 and is guided to the optical fiber coupler 28.

  The optical fiber coupler 28 is optically connected to the optical fibers FB7, FB8, FB9, and FB10. The optical fiber coupler 28 is guided from the circulator 26 to the optical fiber coupler 28 and guided from the circulator 24 to the optical fiber coupler 28. The waved return light L3 is combined to generate interference light. The interference light generated by the optical fiber coupler 28 is divided into two interference lights L4 and L5. The interference light L4 enters the optical fiber FB8 and is guided to the detector 30a. The interference light L5 is The light enters the optical fiber FB9 and is guided to the detector 30b.

  The interference lights L4 and L5 guided to the detectors 30a and 30b are converted into electric signals according to their light intensity by the detectors 30a and 30b, respectively, and transmitted to the interference light detector 50.

  The interference light detection unit 50 adjusts the balance of the intensity of the interference light L4 and the interference light L5 based on the signals transmitted from the detectors 30a and 30b, and interferes with the light intensity of the interference light L4 by, for example, heterodyne detection. Detect as a signal. Then, the detected interference signal is output to the processing unit 54.

  The processing unit 54 acquires tomographic information from the interference signal detected by the interference light detection unit 50. Although details are omitted, when the sum of the total optical path length of the measurement light L1 and the total optical path length of the return light L3 is equal to the total optical path length of the reference light L2, it is strong or weak at the difference frequency between the reference light L2 and the return light L3. A beat signal that repeats is generated as an interference signal. On the other hand, by moving the position of the base 34 by the mirror moving mechanism 36 in the optical path length adjusting unit 30 and changing the optical path length of the reference light L2, the depth direction of the measuring object S (light emission of the OCT probe apparatus 10). The measurement position with respect to the emission direction of the measurement light L1 from the unit 62 is changed, and a plurality of beat signals at each measurement position are detected. Therefore, based on the position of the base 34 of the optical path length adjustment unit 30 and the interference signal (beat signal) detected by the interference light detection unit 50, the return light from each measurement position in the depth direction of the measurement target S The intensity of L3 is acquired as tomographic information.

  In addition, the light emission part 62 is rotated around the longitudinal axis of the OCT probe apparatus 10 (probe insertion part 70), and the tomographic information is acquired while the measurement light L1 is radially scanned, thereby obtaining a cross section substantially orthogonal to the longitudinal axis. The tomographic information of the entire circumference of the measuring object S can be acquired, and the tomographic information is acquired while moving the light emitting part 62 in the longitudinal axis direction and linearly scanning the measuring light L1, thereby along the longitudinal axis. The tomographic information of the measuring object S in the cross section can be acquired. In addition, radial scanning and linear scanning are performed in parallel (simultaneously or alternately). For example, tomographic information (three-dimensional volume data) of the measurement target S in a three-dimensional region around the longitudinal axis is acquired by spiral scanning. Can do.

  The processing unit 54 visualizes the tomographic information acquired in this way to generate a tomographic image or the like, and outputs and displays it on the monitor device 14 or stores and saves it as data.

  The control operation unit 56 includes input means such as a keyboard and a mouse, and control means for managing various information based on the input information, and is connected to the processing unit 54. The control operation unit 56 inputs, sets, changes, and the like of various processing conditions in the processing unit 54 based on an operator instruction input from the input unit.

  An operation screen for inputting an instruction in the control operation unit 56 may be displayed on the monitor device 14, or a display unit other than the monitor device 14 may be provided and displayed on the display unit. Good.

  Further, the OCT processor 12 uses TD-OCT (Time domain OCT) measurement as an OCT measurement method, but is not limited to this, and an SS-OCT (Swept source OCT) measurement method or SD -It may be one using an OCT (Spectral Domain OCT) measurement method.

  Next, details of the OCT probe apparatus 10 will be described. FIG. 2 is a side view showing the overall appearance of the OCT probe apparatus 10, and FIG. 3 is a side view showing a state in which the OCT probe apparatus 10 is cut along the longitudinal axis and an outer sheath described later is removed. It is sectional drawing.

  As shown in FIGS. 2 and 3, the OCT probe apparatus 10 is attached to a probe insertion portion 70 to be inserted into a body cavity and a proximal end side of the probe insertion portion 70, and is attached to the OCT processor 12 by a fixed-side optical fiber FB2. And a probe driving unit 72 that is optically connected.

  As shown in FIG. 2, the probe insertion portion 70 includes a first probe outer cylinder (inner sheath) 74 and a second probe outer cylinder (outer sheath) 150 fitted on the outer periphery of the inner sheath 74.

  The inner sheath 74 is a flexible long cylindrical member, and is formed of a material that allows the measurement light L1 and the return light L3 to pass therethrough. As shown in FIG. 3, a lumen (main lumen 84) penetrating in the longitudinal axis direction is formed in the inner sheath 74, and a cap 76 that closes the distal end opening of the main lumen 84 is attached to the distal end of the inner sheath 74. ing. Note that the outer diameter of the cap 76 is smaller than the outer diameter of the inner sheath 74.

  In the main lumen 84, the rotation side optical fiber FB1 connected to the fixed side optical fiber FB2 via the optical rotary joint 60 is inserted and disposed from the proximal end side of the inner sheath 74.

  The rotation side optical fiber FB1 has an outer peripheral portion covered with a spring (flexible shaft) 78, and an optical lens 82 constituting the light emitting portion 62 is fixed to a distal end portion by a fixing member 80.

  By the rotation side optical fiber FB1, the measurement light L1 incident on the rotation side optical fiber FB1 from the fixed side optical fiber FB2 via the optical rotary joint 60 is guided to the optical lens 82. On the other hand, the return light L3 from the measuring object S taken in from the optical lens 82 is guided to the optical rotary joint 60 by the rotation side optical fiber FB1, and enters the fixed side optical fiber FB2 through the optical rotary joint 60.

  The optical lens 82 has a tip end formed in a substantially hemispherical shape, and deflects and condenses the measurement light L1 emitted from the tip of the rotation side optical fiber FB1. By this optical lens 82, the measurement light L1 emitted from the distal end portion of the rotation-side optical fiber FB1 is emitted in a direction substantially orthogonal to the longitudinal axis of the probe insertion portion 70 (the optical axis of the rotation-side optical fiber FB1). And is collected, passes through the inner sheath 74, and irradiates the measuring object S. Further, the back scattered light from the measuring object S irradiated with the measurement light L1 passes through the inner sheath 74 as the return light L3, is taken in and collected from the optical lens 82, and is collected on the rotation side optical fiber FB1. Incident from. As will be described later, during measurement, the outer sheath 150 is retracted to a position on the proximal end side, and is set to a position where the measurement light L1 and the return light L3 are not blocked.

  An expandable / contractible (expandable) annular first balloon 86 is attached to the outer peripheral surface of the cap 76, and a side wall portion of the inner sheath 74 is connected to the internal space of the first balloon 86. A discharge lumen 88 is formed in the longitudinal axis direction. The proximal end side of the supply / discharge lumen 88 is connected to the balloon control device 200. As a result, the fluid (gas or liquid) delivered from the balloon control device 200 is injected into the first balloon 86 via the supply / discharge lumen 88, and the first balloon 86 expands (expands). The fluid in the balloon 86 is discharged to the balloon control device 200 via the supply / discharge lumen 88 so that the first balloon 86 is deflated.

  The outer sheath 150 shown in FIG. 2 to be fitted on the inner sheath 74 is a long cylindrical member having flexibility, and has a lumen (main lumen 152) penetrating in the longitudinal axis direction as shown in FIG. Is formed. The outer sheath 150 desirably has higher rigidity than the inner sheath 74 depending on the thickness or material thereof. An inner sheath 74 is inserted into the main lumen 152, and an outer sheath 150 is fitted on the outer periphery of the inner sheath 74. The outer sheath 150 is movable in the longitudinal axis direction with respect to the inner sheath 74. .

  An expandable / contractable annular second balloon 154 is attached to the outer peripheral surface on the distal end side of the outer sheath 150, and a side wall portion of the outer sheath 150 is connected to the internal space of the second balloon 154. A discharge lumen 156 is formed in the longitudinal axis direction. The proximal end side of the supply / discharge lumen 156 is connected to the balloon control device 200. As a result, the fluid (gas or liquid) delivered from the balloon control device 200 is injected into the second balloon 154 via the supply / discharge lumen 156, and the second balloon 154 expands. This fluid is discharged to the balloon control device 200 through the supply / discharge lumen 156 so that the first balloon 86 is deflated.

  The probe driving unit 72 shown in FIG. 2 provided on the proximal end side of the probe insertion unit 70 is entirely covered with the case 100, and as shown in FIG. 3, the fixing member 101 (or the fixing member 101 fixed in the case 100 (or The base end portion of the inner sheath 74 of the probe insertion portion 70 is fixed to the case 100 itself.

  The optical rotary joint 60 is accommodated in the case 100 of the probe driving unit 72, and the optical rotary joint 60 is composed of a fixed cylinder 104 and a rotary cylinder 106.

  The fixed cylinder 104 is fixed to a frame 102 that is supported so as not to rotate with respect to the case 100, and a fixed-side optical fiber FB <b> 2 is attached to the base end side of the fixed cylinder 104.

  The rotating cylinder 106 is rotatably supported by the fixed cylinder 104, and a rotating side optical fiber FB1 and a flexible shaft 78 are attached to the distal end side of the rotating cylinder 106.

  Although details are omitted, the fixed cylinder 104 and the rotary cylinder 106 have an internal hollow portion in communication, and the fixed-side optical fiber FB2 and the rotary-side optical fiber FB1 are optically connected through the hollow portion. Yes. As a result, the rotating cylinder 106 rotates with respect to the fixed cylinder 104, so that the rotating side optical fiber FB1 rotates optically within the inner sheath 74 with respect to the fixed side optical fiber FB2. ing.

  A rotating shaft of a motor 110 fixed to the frame 102 is connected to the rotating cylinder 106 via a gear (gear train) 108, and the rotating cylinder 106 is rotated by driving the motor 110. . As a result, the rotation side optical fiber FB1 and the flexible shaft 78 are rotated by the motor 110, and the optical lens 82 is rotated inside the inner sheath 74 in conjunction with this rotation so that radial scanning is performed.

  Further, a support member 112 protrudes from the frame 102, and a screw hole (not shown) is formed in the support member 112. A forward / backward moving ball screw 114 is screwed into the screw hole, and a rotary shaft of a motor 116 fixed to the case 100 is connected to the forward / backward moving ball screw 114.

  Accordingly, by driving the motor 116, the frame 102 moves forward and backward with respect to the case 100, and the optical rotary joint 60 moves forward and backward in the optical axis direction. Then, when the optical rotary joint 60 moves back and forth with respect to the case 100, the rotation-side optical fiber FB1 and the flexible shaft 78 move relative to the inner sheath 74 in the optical axis direction of the rotation-side optical fiber FB1 (the length of the probe insertion portion 70). The optical lens 82 attached to the distal end of the rotation side optical fiber FB1 advances and retreats inside the inner sheath 74, and linear scanning is performed.

  Next, the operation of the OCT probe apparatus 10 will be described by taking as an example the case of measuring the inner wall of the bile duct (the common bile duct) (acquiring tomographic information).

  When the probe insertion unit 70 is inserted into the bile duct and the measurement is performed, for example, as shown in FIG. 4, the insertion unit 260 of a side-view type endoscope is inserted from the patient's mouth, and the duodenal furter papilla is inserted. It inserts from the observation window arrange | positioned to the side of the front-end | tip of the part 260 to the position observed. Subsequently, the probe insertion section 70 is inserted into a treatment instrument insertion channel that is inserted through the insertion section 260 of the endoscope, and the probe insertion section 70 is moved from the treatment instrument outlet port that opens toward the side of the insertion section 260. Let it be pulled out and insert it into the bile duct from the papilla. And the probe insertion part 70 is inserted to the desired measurement site | part in a bile duct.

  The state of the main components of the probe insertion portion 70 when the probe insertion portion 70 is inserted to a desired measurement site in the bile duct (when the probe is inserted) is shown in the side sectional view of FIG. As shown in the figure, when the probe is inserted, the distal end of the outer sheath 150 protrudes forward from the distal end of the inner sheath 74, and the first balloon 86 held by the inner sheath 74 (cap 76) is inserted into the outer sheath 150. In other words, the first balloon 86 is accommodated in the main lumen 152 of the outer sheath 150. In addition, as shown in the figure, it is desirable that the tapered tip end portion of the cap 76 is projected forward from the tip of the outer sheath 150. Further, the first balloon 86 is expanded by the balloon control device 200 and the outer peripheral surface of the first balloon is pressed against the inner peripheral surface of the side wall portion of the outer sheath 150 so that the outer sheath 150 is fixed to the inner sheath 74. To do.

  As a result, only one of the two balloons of the first balloon 86 and the second balloon 154 is exposed to the outside, so that compared to the case where the two balloons are exposed to the outside, The operation of inserting the probe insertion part 70 into the small-diameter bile duct becomes easy. In addition, the outer sheath 150 and the inner sheath 74 (and the contents in the inner sheath 74) can be inserted as an integral part to the measurement site. For example, by pushing the outer sheath 150 into the treatment instrument insertion channel, the inner sheath 74 can be inserted. In addition, since the probe is inserted into the bile duct together with the outer sheath 150 while maintaining the positional relationship with the outer sheath 150, the probe insertion portion 70 can be easily inserted into the bile duct. In addition, extraction from the measurement site | part of the probe insertion part 70 after completion | finish of a measurement can be performed in the same state as the time of probe insertion.

  When the probe insertion section 70 is inserted up to a desired measurement site in the bile duct as shown in FIG. 4, the measurement is then performed with the probe insertion section 70 in the measurement state shown in FIG. FIG. 7 is a side sectional view showing the state of the main components of the probe insertion portion 70 during measurement. As shown in FIGS. 5 and 7, at the time of measurement, the distal end of the inner sheath 74 projects forward from the distal end of the outer sheath 150, and a range of a predetermined length from the distal end of the inner sheath 74 to the proximal end side. Is measured as a measurable measurement region (scan region) 160, and is exposed in front of the distal end of the outer sheath 150. Further, the first balloon 86 and the second balloon 154 are enlarged by the balloon control device 00, and the outer peripheral surfaces of the first balloon 86 and the second balloon 154 are pressed and locked to the inner wall surface of the bile duct. As a result, the distal end portion of the inner sheath 74 and the distal end portion of the outer sheath 150 can be fixed near the center in the bile duct (near the central axis of the bile duct), and the measurement area 160 can be entirely covered by the center in the bile duct. Can be fixed nearby.

  Here, an operation method when the probe insertion portion 70 is shifted from the state at the time of probe insertion as shown in FIGS. 4 and 6 to the state at the time of measurement as shown in FIGS. 5 and 7 will be described. As a first method, as shown in FIG. 4, when the probe insertion portion 70 is inserted to a desired measurement site in the bile duct in the state at the time of probe insertion, the inner sheath 74 is extended to the far end of the region to be the measurement site. Insert the tip. Thereafter, the first balloon 86 is temporarily deflated by the balloon control device 200 so that the outer sheath 150 can move forward and backward in the longitudinal axis direction with respect to the inner sheath 74. Next, the outer sheath 150 is moved to the proximal end side with respect to the inner sheath 74, and a range corresponding to a predetermined length from the distal end of the inner sheath 74 to the proximal end, that is, a range of the measurement region (scan region) 160 is set. It is exposed at the distal end side of the outer sheath 150. And the 1st balloon 86 and the 2nd balloon 154 are expanded by the balloon control apparatus 200, and the outer peripheral surface of the 1st balloon 86 and the 2nd balloon 154 is pressed on the inner wall face of a bile duct. As a result, the probe insertion portion 70 can be shifted to the measurement state as shown in FIGS.

  As a second method, as shown in FIG. 4, when the probe insertion portion 70 is inserted up to a desired measurement site in the bile duct in the state when the probe is inserted, the outer sheath 150 is extended to the front end of the region to be the measurement site. Insert the tip. Thereafter, the second balloon 154 is expanded by the balloon control device 200, and the outer peripheral surface of the second balloon 154 is pressed against the inner wall surface of the bile duct. Thereby, the distal end portion of the outer sheath 150 is fixed in the bile duct. Next, the first balloon 86 is temporarily deflated by the balloon control device 200 so that the inner sheath 74 can move forward and backward in the longitudinal axis direction with respect to the outer sheath 150. Subsequently, the inner sheath 74 is moved to the distal end side with respect to the outer sheath 150, and a range corresponding to a predetermined length from the distal end to the proximal end side of the inner sheath 74, that is, a range of the measurement region (scan region) 160 is moved outward. The sheath 150 is exposed at the distal end side. And the 1st balloon 86 is expanded by the balloon control apparatus 200, and the 1st balloon 86 outer peripheral surface is pressed on the inner wall face of a bile duct. As a result, the probe insertion portion 70 can be shifted to the measurement state as shown in FIGS.

  In both the first method and the second method, the first balloon 86 and the second balloon 154 are expanded and pressed against the inner wall surface of the bile duct, and then the inner sheath 74 is moved forward, Alternatively, by moving the outer sheath 150 to the proximal end side, it is possible to stretch the wrinkles on the inner wall surface of the bile duct.

  After the probe insertion portion 70 is brought into the measurement state as described above, the optical lens 82 in the inner sheath 74 is driven by the probe drive portion 72, and radial scanning or linear scanning within the range of the measurement region 160, or these Measurement is performed by performing both of these scans in parallel, and tomographic information of the inner wall of the lumen is acquired. At this time, the optical lens 82 is rotated within the range of the measurement region 160 to perform radial scanning, so that the entire circumference (360 ° range) around the central axis of the bile duct is approximately in the depth direction (radial direction). The tomographic information of the side wall of the bile duct of equal length can be acquired at a time. Further, within the measurement region 160, the optical lens 82 is moved back and forth to perform radial scanning and linear scanning in parallel, thereby obtaining tomographic information in a substantially cylindrical region about the central axis of the bile duct as three-dimensional volume data. You can also get as

  In the above description, the probe insertion unit 70 is inserted into the bile duct and the measurement is performed. However, the probe insertion unit 70 is also applied to the lumen of an arbitrary site such as the biliary tract or the pancreatic duct in the same manner as described above. Insertion can be measured.

  Next, an additional configuration applicable to the probe insertion unit 70 will be described.

  As shown in FIGS. 6 and 7, on the outer peripheral surface of the side wall portion of the inner sheath 74, a mark 170 indicating the position of the proximal end of the outer sheath 150 when the probe is inserted (FIG. 6), and at the time of measurement (FIG. 7) When the mark 172 indicating the position of the proximal end of the outer sheath 150 is marked, even when the probe insertion portion 70 is inserted into the body cavity, the reference mark 170 is referred to as shown in FIG. It is possible to easily set the probe insertion state. Further, by referring to the mark 172, the measurement region 160 can be set to a predetermined length. The mark 172 may be provided at a plurality of positions so that a desired length can be selected from a plurality of different predetermined lengths of the measurement region 160.

  Although not shown in the figure, X-ray imaging is performed by providing X-ray markers with low X-ray transmittance at positions corresponding to both ends in the longitudinal axis direction of the measurement region 160 on the outer peripheral surface of the inner sheath 74 and the like. Thus, the measurement region 160 may be determined from the position of the X-ray marker imaged in the X-ray image. In addition, when the length of the measurement region 160 in the longitudinal axis direction can be arbitrarily set, an X-ray is applied to the position on the distal end side of the inner sheath 74 (the distal end side of the measurement region 160) and the distal end of the outer sheath 150. A marker may be provided.

  Further, as shown in the perspective view showing the state of the probe insertion portion 70 in FIGS. 8A to 8C at the time of measurement, a suction lumen 180 and a contrast medium injection lumen 182 are provided on the side wall portion of the outer sheath 150. Are formed along the longitudinal axis direction, and openings on the distal end side of the lumens 180 and 182 are provided on the distal end surface of the side wall portion of the outer sheath 150 (at least on the distal end side with respect to the second balloon 154). A suction tool or a contrast medium injection tool may be connected to the opening on the proximal end side of 182. The lumens 180 and 182 may be configured so that one lumen is properly used as a suction lumen and a contrast agent injection lumen. According to this, as in FIGS. 5 and 7, after the probe insertion portion 70 is brought into the insertion state as shown in FIG. 8A, the first balloon 86 is connected to the first balloon 86 by the suction tool via the suction lumen 180. The gas (or liquid) in the space between the second balloons 154 can be sucked, whereby the wall surface of the living body (measurement target S) in the measurement region 160 is made to pass through the inner sheath 74 as shown in FIG. Measurement can be performed by adsorbing and fixing to the outer peripheral surface.

  8A, after the probe insertion portion 70 is in the state at the time of insertion, the contrast medium injection tool is used between the first balloon 86 and the second balloon 154 through the contrast medium injection lumen 182. By injecting contrast medium P into the space as shown in FIG. 3 and performing X-ray imaging, the lumen of the bile pancreatic duct or the like in the range of the measurement region 160 can be imaged and visualized. If the part 190 has arisen, it can be easily detected.

  In addition to the lumen for the above application, for example, a lumen for supplying liquid or gas for supplying liquid or gas, or a lumen for other applications is provided on the side wall portion of the outer sheath 150 similarly to the lumens 180 and 182. Also good. Further, the above-mentioned lumens for suction, contrast medium injection, liquid feeding, air feeding, etc. can be formed not on the outer sheath 150 but on the inner sheath 74. In this case, the lumen on the distal end side of the lumen is used. The opening can be provided on the proximal end side with respect to the first balloon 86 so as to communicate with the space between the first balloon 86 and the second balloon 154.

  Next, detailed forms of the first balloon 86 and the second balloon 154 of the probe insertion unit 70 will be described.

  FIG. 9 is a front cross-sectional view of the probe insertion section 70 cut in a direction perpendicular to the longitudinal axis. As shown in FIGS. 5 and 7, the distal end of the inner sheath 74 projects forward from the distal end of the outer sheath 150. FIG. 4A shows a front cross-sectional view at the position of the first balloon 86, and FIG. 2B shows the second balloon 154 with respect to the state when the first balloon 86 and the second balloon 154 are expanded. A front sectional view at the position of the balloon 154 is shown. Note that the contents in the first sheath 74 are omitted.

  As described above, the first balloon 86 and the second balloon 154 attached to each of the inner sheath 74 (cap 76 at the distal end) and the outer sheath 150 are both expanded in an annular shape, and the lumen into which the probe insertion portion 70 is inserted. The outer peripheral surfaces (annular surfaces on the outer peripheral side) 250 and 252 that are in contact with the inner wall surface have a substantially circular cross-sectional shape. The positions of the central axes 254 and 256 are respectively the position of the central axis (longitudinal axis) of the inner sheath 74 and the central axis (longitudinal axis) of the outer sheath 150 as shown in FIGS. ) Position. Since the central axis of the inner sheath 74 and the central axis of the outer sheath 150 are arranged substantially coaxially, both central axes are represented as the central axis (longitudinal axis) 260 of the probe insertion portion 74.

  That is, when the first balloon 86 is expanded, the outer peripheral surface 250 of the first balloon 86 isotropically expands in the entire circumferential direction around the central axis 260 of the probe insertion portion 74 (inner sheath 74). On the cross section of FIG. 9A, a circle having a predetermined radius r centering on the central axis 260 is formed. Similarly, for the second balloon 154, when the second balloon 154 is expanded, the outer peripheral surface 252 of the second balloon 154 is circumferentially centered on the central axis 260 of the probe insertion portion 74 (outer sheath 150). 9B, a circle having a predetermined radius r centering on the central axis 260 is formed on the cross section of FIG. 9B.

  Further, when the first balloon 86 and the second balloon 154 are expanded to the maximum, their outer peripheral surfaces 250 and 252 form a substantially cylindrical surface shape, and the cylindrical surface outer peripheral surfaces 250 and 252 The radius r is substantially the same between the first balloon 86 and the second balloon 154. That is, the first balloon 86 and the second balloon 154 can be expanded so that the radii of the outer peripheral surfaces 250 and 252 of the first balloon 86 and the second balloon 154 coincide with each other.

  9, the center axis 254 of the first balloon 86 and the center axis 256 of the second balloon 154 are coaxial (in the measurement state shown in FIGS. 5 and 7). The region between the portions pressed by the first balloon 86 and the second balloon 154 on the inner wall surface of the lumen, that is, probe insertion. The range of the unit 70 facing the measurement region (scan region) 160 (see FIGS. 5 and 7) is corrected to a substantially cylindrical surface (the lumen itself is cylindrical).

  Further, the radial position of the central axis 254 of the inner sheath 74 with respect to the first balloon 86 and the radial position of the central axis 256 of the outer sheath 150 with respect to the second balloon 154 substantially coincide with each other. Since the central axes of the inner sheath 74 and the outer sheath 150 fixed in the lumen by the first balloon 86 and the second balloon 154 are arranged coaxially as the central axis 260 of the probe insertion portion 70, Since the central axis 260 of the probe insertion part 70 is disposed at the positions of the first balloon 86 and the central axes 254 and 256 of the second probe insertion part 70, the range of the measurement region 160 of the probe insertion part 70 is cylindrical. While being fixed near the center of the corrected lumen, it is fixed substantially parallel to the central axis of the lumen (substantially parallel to the inner wall surface). Therefore, measurement data in a range facing the measurement region 160 of the probe insertion unit 70 (a range in the entire circumferential direction around the central axis 260) can be obtained favorably.

  9 is different from the configuration of FIG. 9 in that the positions of the central axis 260 of the probe insertion portion 70 with respect to the first balloon 86 and the second balloon 154 are shifted from the center of the first balloon 86 and the second balloon 154. FIGS. 10A and 10B show a form in which the probe insertion portion 70 is fixed in the lumen at positions eccentric from the central axes 254 and 256, respectively. FIGS. It is a corresponding front sectional view, and the same reference numerals as those in FIG.

  As shown in FIGS. 10A and 10B, both the first balloon 86 and the second balloon 154 are in contact with the inner wall of the lumen into which the probe insertion portion 70 is inserted, as in the embodiment of FIG. 252 has a cross-sectional shape that is substantially circular. The positions of the central axes 254 and 256 are different from the positions of the central axis 260 (the central axes of the inner sheath 74 and the outer sheath 150) of the probe insertion portion 70, respectively. That is, when the first balloon 86 is expanded, the outer peripheral surface 250 of the first balloon 86 is displaced from the central axis 260 of the probe insertion portion 70 (inner sheath 74) on the cross section of FIG. A circle with a predetermined radius r centering on is formed. Similarly, with respect to the second balloon 154, when the second balloon 154 is expanded, the position deviated from the central axis 260 of the probe insertion portion 70 (outer sheath 150) on the cross section of FIG. A circle having a predetermined radius r is formed.

  Further, when the first balloon 86 and the second balloon 154 are expanded to the maximum, their outer peripheral surfaces 250 and 252 form a substantially cylindrical surface shape, and the cylindrical surface outer peripheral surfaces 250 and 252 The radius r is substantially the same between the first balloon 86 and the second balloon 154, and the position of the central axis 260 of the probe insertion portion 70 (inner sheath 74) with respect to the first balloon 86 in the radial direction, and the second balloon 154 The position in the radial direction of the central axis 260 of the probe insertion portion 70 (outer sheath 150) is substantially coincident.

  According to the probe insertion portion 70 in the form of FIG. 10, in the measurement state shown in FIGS. 5 and 7, the center axis 254 of the first balloon 86 and the center of the second balloon 154 are the same as in the form of FIG. The shaft 256 is coaxially arranged, and the area facing the measurement region (scan region) 160 of the probe insertion portion 70 on the inner wall surface of the lumen is substantially cylindrical (as in the embodiment of FIG. The lumen itself is corrected to a cylindrical shape).

  Also, the position of the central axis 260 of the probe insertion portion 70 (inner sheath 74) with respect to the first balloon 86 in the radial direction and the radial position of the central axis 260 of the probe insertion portion 70 (outer sheath 150) with respect to the second balloon 154. Are substantially coincided with each other, that is, the central axes of the inner sheath 74 and the outer sheath 150 fixed in the lumen by the expanded first balloon 86 and the second balloon 154 are the first balloon 86 and the second balloon 150, respectively. Since the balloon 154 is coaxially arranged at a position different from the central axes 254 and 256 of the balloon 154, at least the range of the measurement region 160 of the probe insertion portion 70 is a tube at a position deviated from the center of the lumen corrected to a cylindrical shape. It is fixed substantially parallel to the central axis of the cavity (substantially parallel to the inner wall surface). Therefore, when the measurement target range is not the entire circumferential direction around the central axis of the lumen but the measurement target range is a limited angle direction and a range in the vicinity thereof, the first balloon 86 and the first balloon 86 2 It is fixed in a state where the central axis 260 of the probe insertion portion 70 is biased in the angle direction of the measurement target range with respect to the central axes 254 and 256 of the balloon 154 (a state where the probe insertion portion 70 is close to the measurement target range). Thus, good measurement data regarding the measurement target range can be obtained.

  In the case of the configuration of FIG. 10, the direction opposite to the direction in which the central axis 260 of the probe insertion portion 70 is biased with respect to the central axes 254, 256 of the first balloon 86 and the second balloon 154, that is, probe insertion. Since the measurement related to the direction in which the distance from the central axis 260 of the portion 70 to the outer peripheral surfaces 250 and 252 of the first balloon 86 and the second balloon 154 is the greatest is considered to be less important, the direction or the direction in the vicinity thereof FIG. 8 shows a case in which the supply / discharge lumen 88 (see FIG. 10B) for supplying or discharging the fluid in the first balloon 86 to the side wall portion of the inner sheath 74 or other lumen (provided in the inner sheath 74) is provided. It is preferable to provide lumens for suction, contrast medium injection, liquid feeding, air feeding, etc. In the above embodiment, no means for restricting the rotation of the outer sheath 150 around the central axis with respect to the inner sheath 74 is provided, and it is possible to rotate the inner sheath 74 freely. In order to make the radial position of the central axis of the sheath 74 substantially coincide with the radial position of the central axis of the outer sheath 150 with respect to the second balloon 154 (the central axis 254 of the first balloon 86 and the 2 In order to set the central axis 256 of the balloon 154 to a coaxial position, for example, alignment marks may be provided on the proximal end sides of the inner sheath 74 and the outer sheath 150, or the outer side with respect to the inner sheath 74 may be provided. Restricting means for restricting the rotational position of the sheath 150 around the central axis may be provided.

  DESCRIPTION OF SYMBOLS 10 ... OCT probe apparatus, 12 ... OCT processor, 14 ... Monitor apparatus, 20 ... Light source unit, 50 ... Interference light detection part, 54 ... Processing part, 56 ... Control operation part, 60 ... Optical rotary joint, 62 ... Light emission part , 70 ... Probe insertion part, 72 ... Probe drive part, 74 ... First probe outer cylinder (inner sheath), 78 ... Spring (flexible shaft), 82 ... Optical lens, 84, 152 ... Main lumen, 86 ... First balloon , 150 ... second probe outer tube (outer sheath), 154 ... second balloon, 160 ... measurement region, 180, 182 ... lumen, FB1 ... rotation side optical fiber, FB2 ... fixed side optical fiber

Claims (7)

A light guide means for guiding measurement light for obtaining optical tomographic information of the measurement object;
A light emitting means that is provided at the tip of the light guiding means and emits the measurement light guided by the light guiding means toward the measurement object;
A first mantle tube covering the outside of the light guide means and having at least a tip side made of a light transmissive member;
First expandable / contractible means provided on the first outer tube and capable of expanding / contracting;
A second mantle tube provided so as to be able to advance and retract so as to cover the first mantle tube;
Second expandable / contractible means provided on the second outer tube and capable of expanding / contracting;
With
The radius at the time of expansion of the second expansion / contraction means is substantially the same as the radius at the time of expansion of the first expansion / contraction means, and the second expansion / contraction means with respect to the second expansion / contraction means at the time of expansion of the second expansion / contraction means. The position in the radial direction of the central axis of the second outer tube is the same as the position in the radial direction of the central axis of the first outer tube with respect to the first expansion / contraction means when the first expansion / contraction means is expanded. The
The first outer tube and the second outer tube are provided at positions eccentric from the central axes of the first expansion / contraction unit and the second expansion / contraction unit, respectively. A driving lumen is provided on the side surface for driving the first expansion / contraction means in a direction where the distance from the first outer tube to the peripheral region of the first expansion / contraction means is the largest. An optical tomographic probe. The optical tomographic probe according to claim 1 , wherein the second outer tube is provided with an accommodating portion for accommodating the first expansion / contraction means therein. The second outer tube is formed with a lumen for sucking a space on the distal end side with respect to the second expansion / contraction means and having an opening on the distal end side with respect to the second expansion / contraction means. The optical tomographic probe according to claim 1 or 2 . The second mantle tube has a lumen for injecting a contrast medium into a space on the distal end side with respect to the second expansion / contraction means, the lumen having an opening on the distal end side with respect to the second expansion / contraction means. The optical tomographic probe according to claim 1 , wherein the optical tomographic probe is formed. The optical tom according to any one of claims 1 to 4 , wherein the first mantle tube has a liquid-feeding lumen that opens closer to the base end side than the first expansion / contraction means. Probe for measurement. The liquid feeding lumen is provided on a side surface of the first outer tube in a direction in which the distance from the first outer tube to the peripheral region of the first expansion / contraction means is the largest. The optical tomographic probe according to claim 5 . The optical tomography probe according to any one of claims 1 to 6 , wherein the second outer tube is higher in rigidity than the first outer tube.

Images