JP5904938B2 - てんかんの治療におけるフィトカンナビノイドの１つ又は組合せの使用 - Google Patents

てんかんの治療におけるフィトカンナビノイドの１つ又は組合せの使用 Download PDF

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JP5904938B2
JP5904938B2 JP2012516867A JP2012516867A JP5904938B2 JP 5904938 B2 JP5904938 B2 JP 5904938B2 JP 2012516867 A JP2012516867 A JP 2012516867A JP 2012516867 A JP2012516867 A JP 2012516867A JP 5904938 B2 JP5904938 B2 JP 5904938B2
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seizures
thcv
cbd
seizure
animals
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JP2012532093A (ja
JP2012532093A5 (enExample
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ベン ウォーリー
ベン ウォーリー
ゲイリー スティーヴンス
ゲイリー スティーヴンス
クレア ウィリアムズ
クレア ウィリアムズ
ジェフリー ガイ
ジェフリー ガイ
スティーヴン ライト
スティーヴン ライト
哲朗 菊地
哲朗 菊地
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GW Pharma Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2012516867A 2009-07-03 2010-06-29 てんかんの治療におけるフィトカンナビノイドの１つ又は組合せの使用 Active JP5904938B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0911580.9 2009-07-03
GB0911580A GB2471523A (en) 2009-07-03 2009-07-03 Use of tetrahydrocannibivarin (THCV) and optionally cannabidiol (CBD) in the treatment of epilepsy
PCT/GB2010/051066 WO2011001169A1 (en) 2009-07-03 2010-06-29 Use of one or a combination of phyto-cannabinoids in the treatment of epilepsy

Related Child Applications (1)

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JP2016050485A Division JP2016166205A (ja) 2009-07-03 2016-03-15 てんかんの治療におけるフィトカンナビノイドの１つ又は組合せの使用

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JP2012532093A JP2012532093A (ja) 2012-12-13
JP2012532093A5 JP2012532093A5 (enExample) 2013-08-08
JP5904938B2 true JP5904938B2 (ja) 2016-04-20

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JP2012516867A Active JP5904938B2 (ja) 2009-07-03 2010-06-29 てんかんの治療におけるフィトカンナビノイドの１つ又は組合せの使用
JP2016050485A Pending JP2016166205A (ja) 2009-07-03 2016-03-15 てんかんの治療におけるフィトカンナビノイドの１つ又は組合せの使用

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US (4) US9066920B2 (enExample)
EP (3) EP2727626A1 (enExample)
JP (2) JP5904938B2 (enExample)
KR (1) KR101727000B1 (enExample)
CN (2) CN102596322A (enExample)
AR (1) AR077448A1 (enExample)
AU (1) AU2010267775C1 (enExample)
BR (1) BR112012000076A2 (enExample)
CA (2) CA3040410C (enExample)
CY (1) CY1115338T1 (enExample)
DK (1) DK2448637T4 (enExample)
ES (1) ES2460623T5 (enExample)
GB (3) GB2471523A (enExample)
HR (1) HRP20140398T4 (enExample)
IL (1) IL217280B (enExample)
IN (1) IN2012DN00804A (enExample)
MX (1) MX2012000257A (enExample)
MY (1) MY156759A (enExample)
NZ (2) NZ597704A (enExample)
PL (1) PL2448637T5 (enExample)
PT (1) PT2448637E (enExample)
RU (1) RU2563143C2 (enExample)
SG (1) SG176914A1 (enExample)
SI (1) SI2448637T2 (enExample)
TW (1) TWI461191B (enExample)
UA (1) UA108852C2 (enExample)
WO (1) WO2011001169A1 (enExample)
ZA (1) ZA201200373B (enExample)

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ZA201200373B (en) 2012-09-26
EP2448637A1 (en) 2012-05-09
US9066920B2 (en) 2015-06-30
HRP20140398T1 (hr) 2014-06-20
CA2766082C (en) 2019-06-11
IL217280A0 (en) 2012-02-29
JP2012532093A (ja) 2012-12-13
IN2012DN00804A (enExample) 2015-06-26
US20190247324A1 (en) 2019-08-15
AU2010267775A1 (en) 2012-02-23
US20150335590A1 (en) 2015-11-26
JP2016166205A (ja) 2016-09-15
CN102596322A (zh) 2012-07-18
EP2448637B2 (en) 2022-06-08
US20170273913A1 (en) 2017-09-28
MX2012000257A (es) 2012-01-27
US9522123B2 (en) 2016-12-20
CA3040410A1 (en) 2011-01-06
CA2766082A1 (en) 2011-01-06
KR101727000B1 (ko) 2017-05-02
PT2448637E (pt) 2014-05-27
KR20120088648A (ko) 2012-08-08
GB2471565A (en) 2011-01-05
SI2448637T2 (sl) 2022-10-28
NZ620838A (en) 2015-08-28
AU2010267775B2 (en) 2016-10-06
GB2471565B (en) 2012-07-04
GB201010897D0 (en) 2010-08-11
NZ597704A (en) 2014-05-30
GB0911580D0 (en) 2009-08-12
BR112012000076A2 (pt) 2020-06-02
HK1164766A1 (en) 2012-09-28
DK2448637T4 (da) 2022-09-12
RU2563143C2 (ru) 2015-09-20
IL217280B (en) 2018-05-31
CN106236744A (zh) 2016-12-21
GB2485291A (en) 2012-05-09
ES2460623T3 (es) 2014-05-14
AU2010267775C1 (en) 2020-02-27
TWI461191B (zh) 2014-11-21
GB2471523A (en) 2011-01-05
WO2011001169A1 (en) 2011-01-06
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MY156759A (en) 2016-03-31
DK2448637T3 (da) 2014-05-26
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PL2448637T3 (pl) 2014-08-29
TW201105318A (en) 2011-02-16
CA3040410C (en) 2023-03-28
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AR077448A1 (es) 2011-08-31
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SI2448637T1 (sl) 2014-07-31
EP2727626A1 (en) 2014-05-07
US20120165402A1 (en) 2012-06-28
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