JP5892661B2 - 多能性幹細胞から生殖細胞への分化誘導方法 - Google Patents
多能性幹細胞から生殖細胞への分化誘導方法 Download PDFInfo
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- JP5892661B2 JP5892661B2 JP2013506973A JP2013506973A JP5892661B2 JP 5892661 B2 JP5892661 B2 JP 5892661B2 JP 2013506973 A JP2013506973 A JP 2013506973A JP 2013506973 A JP2013506973 A JP 2013506973A JP 5892661 B2 JP5892661 B2 JP 5892661B2
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0608—Germ cells
- C12N5/0611—Primordial germ cells, e.g. embryonic germ cells [EG]
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/56—Fibrin; Thrombin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Organic Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37356310P | 2010-08-13 | 2010-08-13 | |
| US61/373,563 | 2010-08-13 | ||
| PCT/JP2011/067816 WO2012020687A1 (en) | 2010-08-13 | 2011-07-28 | Method of inducing differentiation from pluripotent stem cells to germ cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013538038A JP2013538038A (ja) | 2013-10-10 |
| JP2013538038A5 JP2013538038A5 (enExample) | 2014-09-11 |
| JP5892661B2 true JP5892661B2 (ja) | 2016-03-23 |
Family
ID=45567656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013506973A Active JP5892661B2 (ja) | 2010-08-13 | 2011-07-28 | 多能性幹細胞から生殖細胞への分化誘導方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9938496B2 (enExample) |
| EP (1) | EP2603583B1 (enExample) |
| JP (1) | JP5892661B2 (enExample) |
| WO (1) | WO2012020687A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10023838B2 (en) | 2013-03-01 | 2018-07-17 | Kyoto University | Method of inducing differentiation from pluripotent stem cells to germ cells |
| US9790468B2 (en) | 2013-03-15 | 2017-10-17 | Avita Iinternational Ltd. | Multifunctional immature dental pulp stem cells and therapeutic applications |
| US11207352B2 (en) | 2013-03-15 | 2021-12-28 | Avita International Ltd. | Compositions comprising stem cells expressing mesenchymal and neuronal markers and uses thereof to treat neurological disease |
| WO2016118824A1 (en) | 2015-01-22 | 2016-07-28 | Regenerative Medical Solutions, Inc. | Markers for differentiation of stem cells into differentiated cell populations |
| US10563171B2 (en) | 2015-06-29 | 2020-02-18 | Kyoto University | Method for inducing differentiation of pluripotent stem cells into germ cells |
| US20200248138A1 (en) * | 2017-06-07 | 2020-08-06 | Kyoto University | Method for inducing differentiation of pluripotent stem cells into germline stem cell-like cells |
| JP7302865B2 (ja) * | 2019-09-12 | 2023-07-04 | 株式会社Dioseve | 未成熟卵母細胞の誘導方法及び成熟卵母細胞の作製方法 |
| EP4346395A4 (en) * | 2021-05-28 | 2025-04-23 | ABS Global, Inc. | In vitro breeding systems and methods in livestock |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4937190A (en) | 1987-10-15 | 1990-06-26 | Wisconsin Alumni Research Foundation | Translation enhancer |
| AU5734998A (en) | 1997-01-10 | 1998-08-03 | Life Technologies, Inc. | Embryonic stem cell serum replacement |
| CA2522050A1 (en) | 2003-04-15 | 2004-10-28 | Kyoto University | Method of growing sperm stem cells in vitro, sperm stem cells grown by the method, and medium additive kit to be used in growing sperm stem cells in vitro |
| US8048999B2 (en) | 2005-12-13 | 2011-11-01 | Kyoto University | Nuclear reprogramming factor |
| GB0622395D0 (en) * | 2006-11-09 | 2006-12-20 | Univ Cambridge Tech | Methods relating to pluripotent cells |
| EP2137296A2 (en) | 2007-03-23 | 2009-12-30 | Wisconsin Alumni Research Foundation | Somatic cell reprogramming |
| JP5124820B2 (ja) * | 2007-05-30 | 2013-01-23 | 国立大学法人 熊本大学 | Es細胞の分化誘導方法 |
| US10023838B2 (en) | 2013-03-01 | 2018-07-17 | Kyoto University | Method of inducing differentiation from pluripotent stem cells to germ cells |
-
2011
- 2011-07-28 WO PCT/JP2011/067816 patent/WO2012020687A1/en not_active Ceased
- 2011-07-28 EP EP11816353.4A patent/EP2603583B1/en active Active
- 2011-07-28 JP JP2013506973A patent/JP5892661B2/ja active Active
- 2011-07-28 US US13/816,681 patent/US9938496B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2603583A4 (en) | 2014-04-16 |
| US9938496B2 (en) | 2018-04-10 |
| EP2603583A1 (en) | 2013-06-19 |
| JP2013538038A (ja) | 2013-10-10 |
| WO2012020687A1 (en) | 2012-02-16 |
| US20130143321A1 (en) | 2013-06-06 |
| EP2603583B1 (en) | 2016-10-05 |
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