JP5847706B2 - 胸骨創感染症を予防するための組成物および方法 - Google Patents

胸骨創感染症を予防するための組成物および方法 Download PDF

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Publication number
JP5847706B2
JP5847706B2 JP2012514044A JP2012514044A JP5847706B2 JP 5847706 B2 JP5847706 B2 JP 5847706B2 JP 2012514044 A JP2012514044 A JP 2012514044A JP 2012514044 A JP2012514044 A JP 2012514044A JP 5847706 B2 JP5847706 B2 JP 5847706B2
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Prior art keywords
poly
tyrosine
derived
lactide
polymer
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Japanese (ja)
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JP2012528866A (ja
JP2012528866A5 (enExample
Inventor
バフレカー，ラマン
モーゼス，アリカ
ブエヴィッチ，ファティマ
プラプラ，サティシュ
マクジェイムズ，ウィリアム・シー
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Medtronic PLC
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TYRX Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0019—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/009—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2012514044A 2009-06-01 2010-06-01 胸骨創感染症を予防するための組成物および方法 Active JP5847706B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47576109A 2009-06-01 2009-06-01
US12/475,761 2009-06-01
PCT/US2010/036910 WO2010141475A1 (en) 2009-06-01 2010-06-01 Compositions and methods for preventing sternal wound infections

Publications (3)

Publication Number Publication Date
JP2012528866A JP2012528866A (ja) 2012-11-15
JP2012528866A5 JP2012528866A5 (enExample) 2013-07-18
JP5847706B2 true JP5847706B2 (ja) 2016-01-27

Family

ID=43298082

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012514044A Active JP5847706B2 (ja) 2009-06-01 2010-06-01 胸骨創感染症を予防するための組成物および方法

Country Status (3)

Country Link
EP (1) EP2437724B1 (enExample)
JP (1) JP5847706B2 (enExample)
WO (1) WO2010141475A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9023114B2 (en) 2006-11-06 2015-05-05 Tyrx, Inc. Resorbable pouches for implantable medical devices
AU2011293344B2 (en) 2010-08-25 2015-07-30 Medtronic, Inc. Novel medical device coatings
CA2816343C (en) 2010-11-12 2017-01-17 Tyrx, Inc. Anchorage devices comprising an active pharmaceutical ingredient
AU2012283875B2 (en) * 2011-07-20 2016-05-12 Medtronic, Inc. Drug eluting mesh to prevent infection of indwelling transdermal devices
EP3065788A1 (en) * 2013-11-08 2016-09-14 Tyrx, Inc. Antimicrobial compositions and methods for preventing infection in surgical incision sites
RU2539394C1 (ru) * 2014-01-15 2015-01-20 государственное бюджетное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО СибГМУ Минздрава России) Способ лечения стерномедиастинита
US10767006B2 (en) * 2017-06-07 2020-09-08 Medtronic, Inc. Hydrogenation of tyrosine derived polyarylates

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5487897A (en) * 1989-07-24 1996-01-30 Atrix Laboratories, Inc. Biodegradable implant precursor
US5099060A (en) 1990-06-12 1992-03-24 Rutgers, The State University Of New Jersey Synthesis of amino acid-derived bioerodible polymers
US5216115A (en) 1990-06-12 1993-06-01 Rutgers, The State University Of New Jersey Polyarylate containing derivatives of the natural amino acid L-tyrosine
US8795242B2 (en) * 1994-05-13 2014-08-05 Kensey Nash Corporation Resorbable polymeric device for localized drug delivery
US6120491A (en) 1997-11-07 2000-09-19 The State University Rutgers Biodegradable, anionic polymers derived from the amino acid L-tyrosine
AU784226B2 (en) * 1999-12-31 2006-02-23 Rutgers, The State University Pharmaceutical formulation for regulating the timed release of biologically active compounds based on a polymer matrix
JP2003155404A (ja) * 2001-11-22 2003-05-30 Yasuhiko Tabata 抗菌剤・高分子複合物及びその製造方法
CN102764247B (zh) * 2004-01-30 2016-04-20 考里安国际公司 递送活性剂的快速溶解膜
US8591531B2 (en) * 2006-02-08 2013-11-26 Tyrx, Inc. Mesh pouches for implantable medical devices
MX2008010126A (es) * 2006-02-08 2010-02-22 Tyrx Pharma Inc Protesis de malla temporalmente rigidizadas.
EP2079491B1 (en) * 2006-10-17 2013-02-27 Reva Medical, Inc. N-substituted monomers and polymers
WO2008127411A1 (en) * 2006-11-06 2008-10-23 Tyrx Pharma, Inc. Mesh pouches for implantable medical devices
MX2009014279A (es) * 2007-06-21 2010-03-26 Tyrx Pharma Inc Cadenas laterales de ester de fenilo para incrementar la resortividad polimerica.

Also Published As

Publication number Publication date
EP2437724A1 (en) 2012-04-11
EP2437724A4 (en) 2013-07-17
EP2437724B1 (en) 2015-09-30
WO2010141475A1 (en) 2010-12-09
JP2012528866A (ja) 2012-11-15

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