JP5802872B2 - 縮合ジイミダゾジアゼピン化合物並びにその使用及び製造方法 - Google Patents
縮合ジイミダゾジアゼピン化合物並びにその使用及び製造方法 Download PDFInfo
- Publication number
- JP5802872B2 JP5802872B2 JP2011529012A JP2011529012A JP5802872B2 JP 5802872 B2 JP5802872 B2 JP 5802872B2 JP 2011529012 A JP2011529012 A JP 2011529012A JP 2011529012 A JP2011529012 A JP 2011529012A JP 5802872 B2 JP5802872 B2 JP 5802872B2
- Authority
- JP
- Japan
- Prior art keywords
- exemplary embodiments
- certain exemplary
- groups
- benzyl group
- group substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9932408P | 2008-09-23 | 2008-09-23 | |
| US61/099,324 | 2008-09-23 | ||
| PCT/US2009/005273 WO2010039187A2 (en) | 2008-09-23 | 2009-09-23 | Fused diimidazodiazepine compounds and methods of use and manufacture thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012503653A JP2012503653A (ja) | 2012-02-09 |
| JP2012503653A5 JP2012503653A5 (cg-RX-API-DMAC10.html) | 2015-04-30 |
| JP5802872B2 true JP5802872B2 (ja) | 2015-11-04 |
Family
ID=42074054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011529012A Active JP5802872B2 (ja) | 2008-09-23 | 2009-09-23 | 縮合ジイミダゾジアゼピン化合物並びにその使用及び製造方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8518901B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2350086B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP5802872B2 (cg-RX-API-DMAC10.html) |
| AU (1) | AU2009300357B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2738650C (cg-RX-API-DMAC10.html) |
| WO (1) | WO2010039187A2 (cg-RX-API-DMAC10.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9322831B2 (en) | 2008-09-23 | 2016-04-26 | The Johns Hopkins University | DDX3 as a biomarker for cancer and methods related thereto |
| US9114158B2 (en) | 2011-03-09 | 2015-08-25 | The Johns Hopkins University | Compounds and methods of use in ablative radiotherapy |
| CA2883577A1 (en) * | 2012-09-04 | 2014-03-13 | Niigata University | Cancer diagnostic and therapeutic method targeting molecules expressed in cancer stem cells |
| WO2015200779A2 (en) * | 2014-06-26 | 2015-12-30 | The Johns Hopkins University | Methods of prevention and treatment of viral disease by use of ddx3 inhibitors |
| JP7796007B2 (ja) * | 2019-09-13 | 2026-01-08 | オリゲニス ゲーエムベーハー | 例えば自己免疫疾患の処置のための、ＬＲＲＫ２、ＮＵＡＫ１および／またはＴＹＫ２キナーゼモジュレータとしての１，４－ジヒドロベンゾ［ｄ］ピラゾロ［３，４－ｆ］［１，３］ジアゼピン誘導体および関連する化合物 |
| US12384788B2 (en) * | 2019-09-13 | 2025-08-12 | Origenis Gmbh | 1,4-dihydrobenzo[d]pyrazolo[3,4-f][1,3]diazepine derivatives and related compounds as LRRK2, NUAK1 and/or TYK2 kinase modulators for the treatment of e.g. autoimmune disease |
| WO2023034743A1 (en) * | 2021-08-31 | 2023-03-09 | Natsar Pharmaceuticals, Inc. | Intravenous formulations of rk-33 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5698155A (en) | 1991-05-31 | 1997-12-16 | Gs Technologies, Inc. | Method for the manufacture of pharmaceutical cellulose capsules |
| TW201311B (cg-RX-API-DMAC10.html) * | 1991-06-17 | 1993-03-01 | Hoffmann La Roche | |
| AU2006342024A1 (en) * | 2005-12-16 | 2007-10-25 | Genentech, Inc. | Tetracyclic kinase inhibitors |
-
2009
- 2009-09-23 JP JP2011529012A patent/JP5802872B2/ja active Active
- 2009-09-23 WO PCT/US2009/005273 patent/WO2010039187A2/en not_active Ceased
- 2009-09-23 CA CA2738650A patent/CA2738650C/en active Active
- 2009-09-23 US US13/061,612 patent/US8518901B2/en active Active
- 2009-09-23 EP EP09818080.5A patent/EP2350086B1/en active Active
- 2009-09-23 AU AU2009300357A patent/AU2009300357B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009300357B2 (en) | 2014-07-03 |
| CA2738650A1 (en) | 2010-04-08 |
| JP2012503653A (ja) | 2012-02-09 |
| WO2010039187A2 (en) | 2010-04-08 |
| WO2010039187A3 (en) | 2010-06-17 |
| EP2350086B1 (en) | 2021-04-21 |
| US8518901B2 (en) | 2013-08-27 |
| CA2738650C (en) | 2017-07-04 |
| US20110275588A1 (en) | 2011-11-10 |
| EP2350086A4 (en) | 2012-06-27 |
| EP2350086A2 (en) | 2011-08-03 |
| AU2009300357A1 (en) | 2010-04-08 |
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