JP5785085B2 - 癒着を処置又は防止するためのポリペプチド - Google Patents
癒着を処置又は防止するためのポリペプチド Download PDFInfo
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- JP5785085B2 JP5785085B2 JP2011533273A JP2011533273A JP5785085B2 JP 5785085 B2 JP5785085 B2 JP 5785085B2 JP 2011533273 A JP2011533273 A JP 2011533273A JP 2011533273 A JP2011533273 A JP 2011533273A JP 5785085 B2 JP5785085 B2 JP 5785085B2
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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- Cardiology (AREA)
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- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US61/106,834 | 2008-10-20 | ||
| PCT/US2009/061345 WO2010065206A1 (en) | 2008-10-20 | 2009-10-20 | Polypeptide for treating or preventing adhesions |
Publications (3)
| Publication Number | Publication Date |
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| JP2012506442A JP2012506442A (ja) | 2012-03-15 |
| JP2012506442A5 JP2012506442A5 (https=) | 2012-12-06 |
| JP5785085B2 true JP5785085B2 (ja) | 2015-09-24 |
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| EP (1) | EP2349310B1 (https=) |
| JP (1) | JP5785085B2 (https=) |
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| CN (1) | CN102256613B (https=) |
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| BR (1) | BRPI0919759A2 (https=) |
| CA (1) | CA2741302C (https=) |
| DK (1) | DK2349310T3 (https=) |
| ES (1) | ES2507496T3 (https=) |
| WO (1) | WO2010065206A1 (https=) |
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| DK2617431T3 (en) | 2007-01-10 | 2017-07-10 | Purdue Research Foundation | Polypeptide inhibitors of HSP27 kinase and applications therefor |
| WO2009021137A2 (en) * | 2007-08-07 | 2009-02-12 | Purdue Research Foundation | Kinase inhibitors and uses thereof |
| EP2378875B1 (en) * | 2008-12-10 | 2018-05-30 | Purdue Research Foundation | Cell-permeant peptide-based inhibitor of kinases |
| US9890195B2 (en) * | 2009-07-27 | 2018-02-13 | Purdue Research Foundation | MK2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration |
| US20130115256A1 (en) * | 2010-05-24 | 2013-05-09 | Cynthia Lander | Methods for treating or preventing vascular graft failure |
| KR101862291B1 (ko) | 2011-04-12 | 2018-05-29 | 모레 매트릭스 인코포레이티드 | 이상 섬유모세포 증식 및 세포외 기질 침착을 특징으로 하는 질병, 질환, 또는 과정을 예방하거나 치료하기 위한 조성물 및 방법 |
| US9890200B2 (en) | 2011-04-12 | 2018-02-13 | Moerae Matrix, Inc. | Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition |
| WO2013134636A1 (en) | 2012-03-09 | 2013-09-12 | Purdue Research Foundation | Compositions and methods for delivery of kinase inhibiting peptides |
| ES2991989T3 (es) * | 2012-03-23 | 2024-12-05 | Macro Biologics Inc | Composiciones y usos de materiales antimicrobianos con propiedades compatibles con tejidos |
| US20140072613A1 (en) * | 2012-09-10 | 2014-03-13 | Cynthia Lander | Compositions and Methods for Treating Cutaneous Scarring |
| WO2016061145A1 (en) * | 2014-10-13 | 2016-04-21 | Symic Biomedical, Inc. | Synthetic proteoglycans for preventing tissue adhesion |
| JP2018501201A (ja) * | 2014-11-17 | 2018-01-18 | モイライ マトリックス インコーポレイテッド | 異常な線維芽細胞増殖および細胞外マトリックス沈着を特徴とする疾患、状態、またはプロセスを予防または処置するための組成物および方法 |
| WO2016112292A1 (en) * | 2015-01-08 | 2016-07-14 | Moerae Matrix, Inc. | Formulation of mk2 inhibitor peptides |
| RU2017135072A (ru) | 2015-03-12 | 2019-04-10 | Мори Матрикс, Инк. | Применение пептидсодержащих композиций ингибитора mk2 для лечения немелкоклеточного рака легкого |
| US11285189B2 (en) | 2017-04-06 | 2022-03-29 | Amicrobe, Inc. | Compositions and uses of locally-applied antimicrobial synthetic cationic polypeptide(s) with enhanced performance and safety |
| RU2741247C1 (ru) * | 2020-10-13 | 2021-01-22 | федеральное государственное бюджетное образовательное учреждение высшего образования "Ростовский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РостГМУ Минздрава России) | Способ профилактики перитонеальных спаек женского таза |
Family Cites Families (18)
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| GB1521000A (en) * | 1975-06-13 | 1978-08-09 | Syntex Puerto Rico Inc | Inhalation device |
| US4192309A (en) * | 1978-09-05 | 1980-03-11 | Syntex Puerto Rico, Inc. | Inhalation device with capsule opener |
| US4227522A (en) * | 1978-09-05 | 1980-10-14 | Syntex Puerto Rico, Inc. | Inhalation device |
| US4778054A (en) * | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
| DK172541B1 (da) * | 1982-10-08 | 1998-12-07 | Glaxo Group Ltd | Apparat til administrering af medikamenter til patienter og en medikamentpakning til brug i apparatet |
| DE3682457D1 (de) * | 1985-07-30 | 1991-12-19 | Glaxo Group Ltd | Geraet zur verabreichung von medikamenten an patienten. |
| JPH05963A (ja) | 1990-04-13 | 1993-01-08 | Toray Ind Inc | ポリペプチド類組成物 |
| JPH07506252A (ja) | 1992-04-24 | 1995-07-13 | エス・アール・アイ・インターナシヨナル | 真核細胞内でのイン・ビボ相同配列ターゲッティング |
| US6582728B1 (en) * | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| EP0733059B1 (en) * | 1993-12-09 | 2000-09-13 | Thomas Jefferson University | Compounds and methods for site-directed mutations in eukaryotic cells |
| WO2003084481A2 (en) * | 2002-04-01 | 2003-10-16 | Arizona Board Of Regents, A Body Corporate Acting On Behalf Of Arizona State University | Biological affinity based delivery systems |
| WO2006071456A2 (en) * | 2004-12-02 | 2006-07-06 | The University Of North Carolina At Chapel Hill | Inhibition of hsp27 phosphorylation for treatment of blistering disorders |
| CA2601823C (en) * | 2005-04-15 | 2016-01-12 | University Of Arizona | Therapeutic peptides for the treatment of metastatic cancer |
| DK2617431T3 (en) * | 2007-01-10 | 2017-07-10 | Purdue Research Foundation | Polypeptide inhibitors of HSP27 kinase and applications therefor |
| US20080293640A1 (en) * | 2007-01-10 | 2008-11-27 | Arizona Board of Regents, A body Corporate, of the State of Arizona, acting for and on behalf of | Polypeptide inhibitors of HSP27 kinase and uses therefor |
| WO2008109794A2 (en) * | 2007-03-08 | 2008-09-12 | Tufts Medical Center | The role of the mk2 pathway in treating fibrosis and scarring |
| WO2009021137A2 (en) * | 2007-08-07 | 2009-02-12 | Purdue Research Foundation | Kinase inhibitors and uses thereof |
| WO2009123759A2 (en) * | 2008-04-02 | 2009-10-08 | Moerae Matrix, Inc. | Therapeutic uses of biocompatible biogel compositions |
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2009
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- 2009-10-20 US US12/582,516 patent/US9034815B2/en not_active Expired - Fee Related
- 2009-10-20 WO PCT/US2009/061345 patent/WO2010065206A1/en not_active Ceased
- 2009-10-20 CA CA2741302A patent/CA2741302C/en not_active Expired - Fee Related
- 2009-10-20 KR KR1020167036610A patent/KR20170001756A/ko not_active Ceased
- 2009-10-20 BR BRPI0919759A patent/BRPI0919759A2/pt not_active Application Discontinuation
- 2009-10-20 DK DK09830789.5T patent/DK2349310T3/da active
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- 2009-10-20 ES ES09830789.5T patent/ES2507496T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012506442A (ja) | 2012-03-15 |
| CN102256613A (zh) | 2011-11-23 |
| KR20170001756A (ko) | 2017-01-04 |
| BRPI0919759A2 (pt) | 2017-03-21 |
| US9034815B2 (en) | 2015-05-19 |
| WO2010065206A1 (en) | 2010-06-10 |
| EP2349310A1 (en) | 2011-08-03 |
| US20100098760A1 (en) | 2010-04-22 |
| US20130101671A9 (en) | 2013-04-25 |
| ES2507496T3 (es) | 2014-10-15 |
| DK2349310T3 (da) | 2014-08-11 |
| AU2009322865B2 (en) | 2013-07-18 |
| AU2009322865A1 (en) | 2010-06-10 |
| CN102256613B (zh) | 2014-09-10 |
| KR20110095867A (ko) | 2011-08-25 |
| CA2741302A1 (en) | 2010-06-10 |
| CA2741302C (en) | 2017-02-28 |
| EP2349310B1 (en) | 2014-07-23 |
| KR101884616B1 (ko) | 2018-08-06 |
| EP2349310A4 (en) | 2012-11-21 |
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Free format text: JAPANESE INTERMEDIATE CODE: R250 |
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| LAPS | Cancellation because of no payment of annual fees |