JP5785077B2 - 崩壊温度より高温での凍結乾燥 - Google Patents
崩壊温度より高温での凍結乾燥 Download PDFInfo
- Publication number
- JP5785077B2 JP5785077B2 JP2011522218A JP2011522218A JP5785077B2 JP 5785077 B2 JP5785077 B2 JP 5785077B2 JP 2011522218 A JP2011522218 A JP 2011522218A JP 2011522218 A JP2011522218 A JP 2011522218A JP 5785077 B2 JP5785077 B2 JP 5785077B2
- Authority
- JP
- Japan
- Prior art keywords
- temperature
- freeze
- collapse
- less
- primary drying
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8642608P | 2008-08-05 | 2008-08-05 | |
US61/086,426 | 2008-08-05 | ||
PCT/US2009/052852 WO2010017296A1 (en) | 2008-08-05 | 2009-08-05 | Lyophilization above collapse |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2011530524A JP2011530524A (ja) | 2011-12-22 |
JP2011530524A5 JP2011530524A5 (en11) | 2012-09-13 |
JP5785077B2 true JP5785077B2 (ja) | 2015-09-24 |
Family
ID=41401614
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2011522218A Active JP5785077B2 (ja) | 2008-08-05 | 2009-08-05 | 崩壊温度より高温での凍結乾燥 |
Country Status (6)
Country | Link |
---|---|
US (1) | US9884019B2 (en11) |
EP (2) | EP2323629B1 (en11) |
JP (1) | JP5785077B2 (en11) |
CA (1) | CA2729972C (en11) |
ES (2) | ES2968301T3 (en11) |
WO (1) | WO2010017296A1 (en11) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2665902A1 (en) * | 2006-10-03 | 2008-04-10 | Wyeth | Lyophilization methods and apparatuses |
AU2007234612B2 (en) * | 2006-12-14 | 2013-06-27 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein stabilization formulations |
US7678764B2 (en) | 2007-06-29 | 2010-03-16 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein formulations for use at elevated temperatures |
EP2187932B1 (en) | 2007-08-07 | 2015-01-28 | DePuy Synthes Products, LLC | Protein formulations comprising gdf-5 in aqueous acidic solution |
WO2009129101A1 (en) * | 2008-04-14 | 2009-10-22 | Advanced Technologies And Regenerative Medicine, Llc | Liquid buffered gdf-5 formulations |
EP2968498A4 (en) | 2013-03-15 | 2016-09-07 | Biogen Ma Inc | PREPARATIONS CONTAINING FACTOR IX POLYPEPTIDE |
US11576863B2 (en) | 2013-03-15 | 2023-02-14 | Takeda Pharmaceutical Company Limited | Formulation of an antibody and use thereof |
EP3123090A4 (en) * | 2014-03-24 | 2017-12-13 | Bioverativ Therapeutics Inc. | Lyophilized factor ix formulations |
EP3323410A1 (en) * | 2016-11-22 | 2018-05-23 | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. | Pharmaceutical parenteral formulation containing carglumic acid |
CN107543373B (zh) * | 2017-09-06 | 2019-04-26 | 华派生物工程集团有限公司 | 一种活疫苗的冷冻干燥方法 |
CN112739323A (zh) | 2018-05-10 | 2021-04-30 | 瑞泽恩制药公司 | 含有高浓度vegf受体融合蛋白的制剂 |
CN109369821B (zh) * | 2018-11-28 | 2021-12-14 | 四川恒通动保生物科技有限公司 | 一种黄芪多糖的高效提取制备方法 |
CR20210435A (es) | 2019-02-18 | 2021-09-20 | Lilly Co Eli | Formulación de anticuerpos terapéuticos |
CA3168873A1 (en) * | 2020-02-04 | 2021-08-12 | Regeneron Pharmaceuticals, Inc. | Target residual moisture content for lyophilized drug product |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5298261A (en) | 1992-04-20 | 1994-03-29 | Oregon Freeze Dry, Inc. | Rapidly distintegrating tablet |
EP0762869A1 (en) * | 1994-06-03 | 1997-03-19 | The Procter & Gamble Company | Fast dissolving dosage forms |
DE60035260T2 (de) * | 1999-02-22 | 2007-10-18 | The University Of Connecticut, Farmington | Neue albuminfreie faktor viii formulierungen |
GB9908014D0 (en) * | 1999-04-08 | 1999-06-02 | Scherer Corp R P | Pharmaceutical compositions |
GB0404586D0 (en) * | 2004-03-01 | 2004-04-07 | Britannia Pharmaceuticals Ltd | Improvements in or relating to organic materials |
CA2569276C (en) * | 2004-06-02 | 2018-01-23 | Victor Bronshtein | Preservation by vaporization |
DE602005022895D1 (de) * | 2004-08-12 | 2010-09-23 | Schering Corp | Stabile pegylierte interferon-formulierung |
WO2006029467A1 (en) * | 2004-09-16 | 2006-03-23 | Btf Pty Ltd | Rapid freeze drying process |
WO2006081320A2 (en) * | 2005-01-27 | 2006-08-03 | Human Genome Sciences, Inc. | Pharmaceutical formulation |
EP1962907A2 (en) * | 2005-12-21 | 2008-09-03 | Wyeth a Corporation of the State of Delaware | Protein formulations with reduced viscosity and uses thereof |
-
2009
- 2009-08-05 ES ES19181153T patent/ES2968301T3/es active Active
- 2009-08-05 WO PCT/US2009/052852 patent/WO2010017296A1/en active Application Filing
- 2009-08-05 CA CA2729972A patent/CA2729972C/en active Active
- 2009-08-05 EP EP09791186.1A patent/EP2323629B1/en active Active
- 2009-08-05 EP EP19181153.8A patent/EP3572073B1/en active Active
- 2009-08-05 JP JP2011522218A patent/JP5785077B2/ja active Active
- 2009-08-05 ES ES09791186T patent/ES2755029T3/es active Active
- 2009-08-05 US US12/536,321 patent/US9884019B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
ES2755029T3 (es) | 2020-04-21 |
EP2323629B1 (en) | 2019-10-09 |
CA2729972A1 (en) | 2010-02-11 |
EP3572073A1 (en) | 2019-11-27 |
ES2968301T3 (es) | 2024-05-08 |
CA2729972C (en) | 2018-11-20 |
EP2323629A1 (en) | 2011-05-25 |
JP2011530524A (ja) | 2011-12-22 |
US20100041870A1 (en) | 2010-02-18 |
EP3572073B1 (en) | 2023-12-20 |
EP3572073C0 (en) | 2023-12-20 |
US9884019B2 (en) | 2018-02-06 |
WO2010017296A1 (en) | 2010-02-11 |
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