JP5760910B2 - Safety cabinet - Google Patents

Description

  The present invention relates to a safety cabinet capable of maintaining a negative pressure in a work space.

  Since drugs such as anticancer drugs mixed with the infusion liquid cause a risk of exposure, mixed injection processing for mixing and adjusting such drugs in the infusion liquid is performed in a safety cabinet set to a negative pressure. When co-injection using a vial filled with a powdered drug as the drug, the drug compounder sucks the infusion from the infusion bag with a syringe, passes the syringe needle of the syringe through the cap of the vial, The infusion solution in the syringe is poured into the vial. Moreover, not only the said vial bottle but the mixed injection process which inject | pours the chemical | medical solution in an ampule into an infusion solution is also performed. In the mixed injection process using the above ampule, the drug solution in the ampoule with the head cut off is sucked into the syringe, the injection needle of the syringe is inserted into the mixed injection port of the infusion bag, and the drug solution in the syringe is injected into the infusion bag. become. Such mixed injection processing and a safety cabinet are disclosed in Patent Document 1.

  Patent Document 2 discloses a radiopharmaceutical dispensing apparatus that dispenses while avoiding the risk of exposure to radiation drugs. The radiopharmaceutical dispensing apparatus includes a syringe holding means for holding a syringe, a first lifting / lowering means for moving the syringe holding means up and down, a piston part holding means for holding a piston part of the syringe, and the piston part holding means. A second raising / lowering means for moving the syringe up and down, and a rotating mechanism for rotating the syringe holding means, the first raising / lowering means, the piston part holding means, and the second raising / lowering means halfway.

  Therefore, it is conceivable to construct a device that mechanically performs the mixed injection process and to deploy this device in the safety cabinet.

JP 2010-29738 A JP-A-1-244759

  However, in the safety cabinet, since it is required to keep the air clean while making the working space negative pressure, an inlet is provided on the bottom plate near the opening / closing window of the safety cabinet, and the opening / closing window is opened. Occasionally, outside air that enters through the opening / closing window is sucked from the intake port. For this reason, when the co-infusion apparatus for performing the co-infusion process is arranged on the bottom plate, the co-infusion apparatus is covered above the intake port, and there is a possibility that outside air intake is not appropriately performed. On the other hand, it is conceivable to lengthen the working space and shift the co-infusion apparatus to the back side so that the co-infusion apparatus does not cover the intake port. However, if it does in this way, it will be necessary to put an extra hand in the back | inner side by the part which shifted the said co-infusion apparatus in the back | inner side, and workability | operativity will fall.

  In view of the above circumstances, the present invention provides a safety cabinet that can appropriately guide outside air to an air intake port that sucks in outside air that enters through an opening / closing window, and that can achieve good workability without increasing the depth of the work space. To do.

  In order to solve the above-described problems, a safety cabinet according to the present invention is a safety cabinet capable of keeping a working space at a negative pressure, and a duct portion formed outside the working space, and a front end side of the duct portion. A front end opening provided; a door that opens and closes the work space; an opening / closing window provided in the door; an inlet portion provided in the door for taking in air flowing into the work space from the opening / closing window; And an air intake duct having an outlet portion for taking out air taken in from the inlet portion and communicating with the front end opening when the door is closed.

  In such a configuration, since the intake duct for sucking outside air entering from the opening / closing window is provided in the door, even if any device is arranged in the work space, the device is not attached to the intake duct. The entrance portion is not covered, and the outside air can be appropriately guided to the intake duct that sucks in outside air entering from the opening / closing window. Moreover, it is not necessary to increase the depth of the work space and shift the device to the back side, so that good workability can be ensured.

  In the safety cabinet, an air intake device and an exhaust device are provided on the ceiling side of the safety cabinet body, outside air sucked by the air intake device is supplied into the work space, and air passing through the duct portion is exhausted from the exhaust air. The device may be guided to the ceiling side and exhausted to the outside.

  In such a safety cabinet, the inlet portion of the intake duct may be located on the back side of the opening / closing window, and the outlet portion of the intake duct may be located below the opening / closing window.

  In such a safety cabinet, a mixed injection device may be provided in the work space.

  According to the present invention, even if any device is arranged in the work space, it is possible to appropriately guide the outside air to the intake port for sucking in the outside air entering from the opening / closing window, and it is preferable that the depth of the work space is not increased. There is an effect that a good workability can be secured.

It is the perspective view which showed the safety cabinet which concerns on one Embodiment of this invention. It is the perspective view which showed the co-infusion apparatus provided in the safety cabinet of FIG. It is the perspective view which showed the mixing process part in the mixed injection apparatus of FIG. It is the perspective view which showed the state of delivery of the vial bottle by the mixing process part and container holding | maintenance part in the mixed injection apparatus of FIG. It is the perspective view which expanded and showed the mixed injection operation part in the mixed injection apparatus of FIG. It is the front view which showed the co-injection operation part and rotation drive part in the co-infusion apparatus of FIG. It is the perspective view which showed the 3rd moving part in the mixed injection apparatus of FIG. FIGS. 4A and 4B are front views showing the container inclined portion provided in the third moving portion, respectively. It is the front view which showed the rotation drive part in the mixed injection apparatus of FIG. It is the front view which showed the rotation drive part, the infusion back holding | maintenance part, the infusion back movement part, and the infusion back inclination part in the mixed injection apparatus of FIG. It is the perspective view which simplified and showed the state which opened the door in the safety cabinet of FIG. FIG. 2 is a perspective view showing the flow of air in the safety cabinet by removing a part of the external components from the safety cabinet of FIG. 1.

Embodiments of the present invention will be described below with reference to the accompanying drawings.
As shown in FIG. 1, the co-infusion apparatus 1 is accommodated in the work space of the safety cabinet 100 according to the present invention, and the operator A opens the opening / closing window 111 covering the opening of the safety cabinet 100 to Work on the co-infusion apparatus 1 (installation of a vial 10, a syringe 11, an infusion bag 12, and the like described later) can be performed. The opening / closing window 111 is provided on the door 110 of the safety cabinet 100. When the door 110 is opened, the space in front of the co-infusion apparatus 1 is opened so that the co-infusion apparatus 1 can be easily attached / detached and maintained. Details of the interior of the door 110 and the safety cabinet 100 will be described later.

  A display 101, a barcode reader 102, and the like are provided on the outer surface of the safety cabinet 100, and the operator A causes the barcode reader 102 to read the barcode added to the mixed injection procedure when starting the processing. A controller (microcomputer) (not shown) is identified by the above read barcode, and includes patient information, doctor information, mixed injection operation program, prescription content information (type and number of drugs used), adjustment procedure information (dissolution) Original / dissolved chemicals, work contents, volume / dissolved amount, sampling amount) are read from the storage unit. The mixed injection operation program differs depending on the type of drug container (whether a vial or ampoule is used), and the number of repetitions of the predetermined operation is determined by the number of drug containers used. When the operator A makes necessary preparations and performs a predetermined operation, the controller starts the co-infusion process in the co-infusion apparatus 1.

  As shown in FIG. 2, for example, the mixed injection device 1 includes conveying devices 2 </ b> A and 2 </ b> B that convey vials 10 that are drug containers, a mixing processing unit 3 that rocks the vials 10, and the vials 10. And the mixed injection operation unit 4 that performs operations on the syringe 11, the infusion back holding unit 5 that holds the infusion bag 12, and the infusion back moving unit that moves the infusion back holding unit 5 closer to or away from the mixed injection operation unit 4 side. 6 and an infusion back inclined portion 7 for inclining the infusion back holding portion 5 by inclining the infusion back moving portion 6 and the transport devices 2A and 2B for approaching or moving away from the mixed injection operation portion 4 side. A drive unit (not shown) and a base 9 on which the mixed injection operation unit 4 and the drive unit are provided and which support the transfer devices 2A and 2B are provided.

  The transfer device 2A and the transfer device 2B are independent and can be moved straight toward the mixed injection operation unit 4 separately. Each of the transfer devices 2 </ b> A and 2 </ b> B includes a lateral movement mechanism for moving the vial 10 set in the container setting unit 21 to the front of the mixed injection operation unit 4. The lateral movement mechanism includes a feed screw 24, a nut member 25 screwed to the feed screw 24, a slide plate 26 connected to the nut member 25, and a motor 27 that rotates the feed screw 24. . A plurality of the container setting portions 21 are provided on the slide plate 26. The container setting portion 21 is provided with an operation pin 21a. When the operation pin 21a is pushed in, the claw of the container setting portion 21 is opened and the vial bottle 10 can be set. The container setting portion 21 is also provided with the operation pins 21a on the back side. When the operation pins 21a hit a contact surface (not shown) disposed on the front side of the mixed injection operation portion 4, the container setting portion 21 The claw 21 is opened, and the vial holder 10 of the mixed injection operation unit 4 can receive the vial 10 on the container setting unit 21.

  When the transport device 2A and the transport device 2B that are independently operated as described above are used, for example, the patient's vial 10 is transported by the transport device 2A, and the mixed injection processing unit 4 executes the mixed injection processing. Using the time required for the mixed injection process, the operator can set the next vial 10 for the patient in the container setting unit 21 of the transfer device 2B.

  Note that the opening / closing window 111 covering the opening of the safety cabinet 100 may be divided in accordance with the arrangement of the transfer device 2A and the transfer device 2B so as to be opened and closed independently. According to this, it is possible to close only the window portion on the side of the conveying device involved in the mixed injection process, and it is possible to reduce the open area of the window as much as possible and to reduce the entry of outside air into the safety cabinet 100. .

  The mixing processing unit 3 is located below the transfer devices 2A and 2B, the transfer devices 2A and 2B are moved to the mixed injection operation unit 4 side, and the vial 10 is passed to the mixed injection operation unit 4. When the operation is performed, the mixing processing unit 3 sinks below the mixed injection operation unit 4. Moreover, as shown in FIG. 3, the support base 31 which comprises the said mixing process part 3 can move. A front end side of the connecting rod 32 is connected to the lower surface of the support base 31, and a rear end side of the connecting rod 32 is connected to the crankshaft 33. When the crankshaft 33 is rotated by a motor (not shown), the support base 31 is reciprocated in the direction of the arrow in the figure.

  The state shown in FIG. 3 is a state in which the vial 10 is placed sideways across the pair of rollers 34. When the roller 34 is rotated in the same direction in this state, the vial 10 is rotated. The bottom part and the cap part (mouth part) of the vial bottle 10 are supported by the rotation support part of the holder 35. The rotation support part on the side of the bottom part is provided in the main body part 351 of the holder 35, and the rotation support part 35a on the side of the cap part is provided in the movable part 35b. The movable portion 35b is screwed to the feed screw 35c, and the movable portion 35b is linearly moved by the rotation of the feed screw 35c. The upper end portion of the feed screw 35c is connected to a rotation shaft of a motor 36 provided at the upper end portion of the main body 351 of the holder 35, and the feed screw 35c is rotated by the rotation of the motor 36. The vial 10 is held by holding the bottom portion and the cap portion of the vial 10 with the rotation support portion of the holder 35, but the vial 10 is placed across the pair of rollers 34. When the holding state by the holder 35 is released, the vial bottle 10 comes into contact with the surface of the roller 34 by gravity, and after this state is formed, the holding state by the holding portion 35 is formed again. doing.

  Further, as shown in FIG. 4, the lower end of the main body 351 of the holder 35 is connected to the rotation shaft of the motor 37, and the holder 35 is swung by the rotational drive of the motor 37. The When the holder 35 is in an upright state by the swinging, the vial 10 can be delivered to and from the container holding part 436 in the mixed injection operation part 4. The holder 35 receives the vial 10 from the mixed injection operation unit 4 after the infusion is poured into the vial 10. The holder 35 passes the vial 10 to the mixed injection operation unit 4 because the mixing processing unit 3 performs a shaking operation (reciprocating operation by the crankshaft 33 and rotating operation by the roller 34). Later.

  As shown in the perspective view of FIG. 5 and the front view of FIG. 6, the mixed injection operation unit 4 holds the cylinder unit 11 a in the syringe 11 and moves the cylinder unit 11 a in the piston unit moving direction in the syringe 11. 1 moving part 41, the 2nd moving part 42 which holds the end of piston part 11b in syringe 11 and moves the piston part 11b in the piston part moving direction, and container holding part 436 for holding vial 10 A third moving portion 43 that moves the first moving portion 41 in the piston moving direction, a support portion 44 that supports the first moving portion 41, the second moving portion 42, and the third moving portion 43, and the support portion 44 that rotates. And a rotation driving unit 45 that inclines the moving direction of the piston part with respect to the direction of gravity (vertical direction). In this embodiment, the first moving part 41, the second moving part 42, and the support part 44 hold the syringe 11 and change the posture of the syringe 11 and the piston part to the cylinder part 11a in the syringe. A syringe holding portion that performs an operation of changing the insertion amount of 11b is configured.

  The first moving portion 41 is guided in the piston portion moving direction by engaging the slider portion 411 with a pair of guide rails 46 fixed to the support portion 44. A nut portion (not shown) is fixed to the back side of the main body portion of the first moving portion 41. A feed screw 412 is screwed into the nut portion. One end of the feed screw 412 is rotatably supported at the bottom of the support portion 44, and the other end is connected to a rotation shaft of a motor 413 fixed to the wall surface of the support portion 44. The feed screw 412 is rotated by the rotational drive of the motor 413, and the first moving portion 41 is linearly moved along the guide rail 46 by this rotation.

  A holding mechanism 414 for holding the cylinder part 11 a is provided on the surface side of the main body part of the first moving part 41. The holding mechanism 414 includes a pair of claw portions 414a that sandwich the cylinder portion 11a from the lateral direction. The pair of claw portions 414a are respectively screwed into the screw portions of the feed screw 414b having screw portions whose threading directions are opposite to each other. The feed screw 414b is connected to the rotating shaft of the motor 414c. The feed screw 414b is rotated by the rotational drive of the motor 414c, and the rotation causes the pair of claw portions 414a to move toward and away from each other. The pair of claw portions 414a is formed with a recess for accommodating the flange portion of the cylinder portion 11a.

  The second moving part 42 is guided in the moving direction of the piston part by engaging the slider part 421 with the pair of guide rails 46. A nut portion 422 is fixed to the back side of the main body portion of the second moving portion 42. A feed screw 423 is screwed into the nut portion 422. One end of the feed screw 423 is connected to a rotating shaft of a motor (not shown) fixed to the lower portion of the support portion 44, and the other end is supported by a bearing portion 425 fixed to the wall surface of the support portion 44. ing. The feed screw 423 is rotated by the rotation of the motor, and the second moving portion 42 is linearly moved along the guide rail 46 by this rotation.

  A holding mechanism 424 for holding the end portion (saddle-like portion) of the piston portion 11 b in the syringe 11 is provided on the surface side of the main body portion of the second moving portion 42. The holding mechanism 424 has a gap portion having an interval corresponding to the thickness of the end portion of the piston portion 11b. The end of the piston part 11b is held in the gap part, and the piston part 11b is moved in the piston part moving direction by moving the second moving part 42.

  As shown in FIG. 7, the third moving unit 43 includes a first main body 431 and a second main body 432 disposed so as to surround the first main body 431. A guide rail 431 a is fixed laterally on the back side of the first main body 431. A slider portion 432a is fixed to the inner surface side of the back plate of the second main body portion 432, and the slider portion 432a is engaged with the guide rail 431a. That is, the second main body 432 is provided so as to be slidable in the lateral direction intersecting the guide rail 46 with respect to the first main body 431. And the feed screw 431b is provided in the said horizontal direction in the back side of the said 1st main-body part 431, This feed screw 431b is connected with the rotating shaft of the motor 431c. A nut portion 432b is fixed to the inner surface side of the back plate of the second main body portion 432, and the feed screw 431b is screwed to the nut portion 432b. When the rotation shaft of the motor 431c rotates, the second main body 432 is slid in the lateral direction with respect to the first main body 431.

  The second body portion 432 is provided with a container holding portion 436 (see FIGS. 5 and 6) which will be described later. A container slide part 437 for moving the container holding part 436 in a direction intersecting the piston part moving direction by the second main body part 432, the slider part 432a, the guide rail 431a, the motor 431c, the nut part 432b, and the feed screw 431b. Is configured.

  A slider portion 431d is fixed to the first main body portion 431. The third moving part 43 is guided in the moving direction of the piston part by engaging the slider part 431d with the pair of guide rails 46. A nut portion (not shown) is fixed to the back surface side of the first main body portion 431 in the third moving portion 43. A feed screw 433 shown in FIG. 5 is screwed into the nut portion. The feed screw 433 is connected to a rotation shaft of a motor 434 fixed to the support portion 44. The feed screw 433 is rotated by the rotational drive of the motor 434, and the first main body 431 is moved along the guide rail 46 by this rotation. The second body part 432 is connected to the first body part 431 by the container slide part 437, and the first body part 431 and the second body part 432 move together as the third moving part 43. become.

  As shown in FIGS. 8A and 8B, the container holding portion 436 is independently rotated on the surface side of the second main body portion 432 in the third moving portion 43. A container inclined portion 435 for inclining the vial 10 is provided. The container holding part 436 is supported by a support part 435 a in the container inclined part 435. The support portion 435a is rotatably provided by a horizontal shaft 435b fixed to the second main body portion 432. Further, a gear portion is formed on the support portion 435a. A worm gear 435c is engaged with the gear portion. The worm gear 435c is formed on the rotation shaft 435d. The rotation shaft 435d is rotated by a motor 435e fixed to the second main body 432. By rotating the motor 435e, the support portion 435a is rotated, and the container holding portion 436 supported by the support portion 435a is rotated and inclined.

  Further, as shown in FIG. 5, the container holding part 436 includes a pair of claw parts 436 a that sandwich the vial bottle 10 from the lateral direction. The pair of claw portions 436a are respectively screwed into the screw portions of the feed screw 436b having screw portions whose threading directions are opposite to each other. The feed screw 436b is connected to the rotation shaft of the motor 436c. The feed screw 436b is rotated by the rotational drive of the motor 436c, and the pair of claw portions 436a are moved closer to and away from each other by the rotation. The pair of claws 436a are formed with triangular recesses suitable for holding the vial bottle 10. Also, by controlling the torque of the motor 436c, the claw portion 436a grips the vial 10 and the like with an appropriate force.

  As shown in FIG. 9, the rotation drive unit 45 includes a gear 452 that is rotatably supported by a horizontally disposed cylindrical shaft 451. The cylindrical shaft 451 is provided on a back wall 91 erected on the base 9. A square attachment plate 453 is fixed to the gear 452, and the attachment plate 453 is rotated by the rotation of the gear 452. The support portion 44 is fixed to the mounting plate 453. A worm gear 454 is engaged with the lower side of the gear 452. The worm gear 454 is connected to the rotation shaft of the motor 455, and when the motor 455 rotates, the worm gear 454 is rotated. The motor 455 is fixed to a side wall 92 erected on the base 9. The power supply lines connected to the first, second and third moving parts 41, 42, 43, etc. provided on the support part 44 of the mixed injection operation part 4 can be taken out through the cylindrical shaft 45. I am doing so. The power supply line connected to the first moving unit 41 is stored in the cord storage rail 47 shown in FIG. 2, and the power supply line connected to the third moving unit 43 is connected to the cord storage rail 48. It is stored in.

  As shown in FIG. 10 and FIG. 2, the infusion bag 12 is held by the infusion bag holding unit 5. The infusion back holding part 5 is connected to the infusion back moving part 6 by a connecting part 51. A nut portion 51 a is fixed to the connecting portion 51. In addition, a feed screw 61 is disposed in the infusion back moving portion 6 in the lateral direction, and the nut portion 51 a is screwed to the feed screw 61. A slider portion (not shown) is fixed to the connecting portion 51, and the slider portion is provided on the infusion back movement portion 6 and engaged with a guide rail 63. A motor 62 is fixed to the back side of the main body of the infusion back moving unit 6. The feed screw 61 is connected to the rotating shaft of the motor 62 via a pulley and a belt (not shown). The feed screw 61 is rotated by the rotational drive of the motor 62, the connecting portion 51 is moved by the rotation, and the infusion bag holding portion 5 is moved by the movement of the connecting portion 51. The movement of the infusion bag holding unit 5 is executed when the injection needle of the syringe 11 is inserted into the mixed injection port of the infusion bag 12.

  The infusion back moving part 6 is connected and fixed to the distal end side of the arm part 71 in the infusion back inclined part 7. The rear end portion of the arm portion 71 is externally fitted to the cylindrical shaft 451, and the arm portion 71 swings around the cylindrical shaft 451. The center of the cylindrical shaft 451 is located on the central axis of the cylinder portion 11a of the syringe 11 held by the mixed injection operation portion 4.

  A nut portion 72 is provided on the back surface of the substantially central portion of the arm portion 71. The nut portion 72 is screwed into a feed screw 73 arranged in the vertical direction. The upper end of the feed screw 73 is supported by a bearing 73a, and the lower end is connected to a pulley 73b. The pulley 73b is configured such that the rotational driving force of the motor 73c is transmitted through the pulley 73d and the belt 73e. When the feed screw 73 is rotated by the rotation of the motor 73c, the nut portion 72 is moved up and down, and the arm 71 is swung by the vertical movement. By this swinging, the infusion back moving part 6 is tilted and the infusion back holding part 5 is tilted. The nut portion 72 moved by the feed screw 73 moves up and down along a circular arc locus centering on the cylindrical shaft 451. For this reason, a structure in which one end side of the feed screw 73 is movably provided to absorb the displacement due to the arc locus as described above, or the nut portion 72 that can absorb the displacement due to the arc locus as described above is used.

  FIG. 11 is a perspective view of the safety cabinet as viewed from the front side when the door is open, and FIG. 12 is a perspective view of the internal flow of air when the safety cabinet is viewed from the side. In FIG. 12, the said co-infusion apparatus 1 is simplified and shown with the dashed-two dotted line. The door 110 in the safety cabinet 100 is connected to the main body by a hinge 112 so as to be able to open laterally. The door 110 includes an opening / closing window 111, a motor (not shown), and a mechanism for converting the rotational force of the motor into the lifting power of the opening / closing window 111 so that the opening / closing window 111 can be opened / closed electrically. Yes. The up / down instruction of the opening / closing window 111 can be performed using the foot switch 130 or the like.

  An intake duct 120 is disposed at a lower position of the door 110. The intake duct 120 includes an inlet portion 120a located on the upper side and an outlet portion 120b located on the lower side. When the door 110 is closed, the inlet 120a is located close to the front side of the transfer devices 2A and 2B (see FIG. 2). The top surface height of the inlet portion 120a is approximately the same as the top surface height of the transfer devices 2A and 2B. The air outlet of the outlet portion 120b communicates with the front end opening 100b in the bottom plate lower duct portion 100e formed under the bottom plate 100a of the work space of the safety cabinet 100 when the door 110 is closed. Yes.

  The inlet portion 120 a is formed with a width that is approximately the same as the width of the opening / closing window 111. In addition, the outlet portion 120b is formed with a width approximately equal to the width of the door 110. The inlet 120 a is located on the back side of the opening / closing window 111, and the outlet 120 b is located below the opening / closing window 111. A mesh portion for taking in air is formed at the upper end portion of the inlet portion 120a. Further, a sealing packing is disposed around the air outlet of the outlet part 120b, and the outlet part 120b communicates with the front end opening 100b when the door 110 is closed. Is sealed from the outside.

  A back side vent 100c is formed by a mesh on the bottom plate 100a on the back side of the work space of the safety cabinet 100, and the air in the work space passes below the co-infusion apparatus 1 and the back side vent 100c. To the bottom plate lower duct portion 100e below the work space. In addition, a rear duct portion 100d using a rear space is formed on the back side of the safety cabinet 100, and air flowing through the bottom plate lower duct portion 100e below the work space passes through the rear duct portion 100d and is safe. It is guided to the top side of the cabinet 100. An air intake device (fan, blower) and an exhaust device (fan, blower) (not shown) are provided on the top side of the safety cabinet 100 (the back of the top plate of the work space). The outside air sucked by the intake device is supplied to the work space through a filter, while the air in the safety cabinet 100 sucked by the exhaust device is discharged outside from the ceiling through the filter. The working space of the safety cabinet 100 can be maintained at a negative pressure by adjusting the exhaust amount of the exhaust device and the intake amount of the intake device.

  When the open / close window 111 is completely closed, the air supplied from the intake device into the work space passes through the intake duct 120 and the rear vent 100c, and the bottom plate lower duct under the work space. It flows to the part 100e. On the other hand, when the opening / closing window 111 is opened for the operation of setting or removing the vial bottle 10, the syringe 11 or the like from the co-infusion apparatus 1, outside air tends to enter the work space. Since the duct 120 is discharged to the outside through the bottom plate duct portion 100e below the work space from the inlet portion 120a through the outlet portion 120b, the outside air can be prevented from entering the work space. .

  Here, if the air duct 120 is not provided and, for example, the bottom plate 100a below the transfer devices 2A and 2B is provided with a vent similar to the mesh side vent 100c, the vent from the work space. The air flow toward the mouth may be disturbed, and the amount of outside air entering the work space may increase.

  If the door 110 is provided with the intake duct 120, outside air is not affected by the transfer devices 2A and 2B from the inlet portion 120a of the intake duct 120 and the bottom plate lower duct portion 100e below the work space. Can be discharged to the outside. And since the said intake duct 120 is provided in the said door 110, it becomes unnecessary to lengthen the depth of the said working space and to shift the said co-infusion apparatus 1 to the back side. Therefore, it is not necessary to increase the depth of the work space in this way, so that good workability can be ensured.

  In the above example, the co-infusion apparatus 1 is provided in the work space of the safety cabinet 100. However, the present invention is not limited to this, and a processing apparatus that requires processing in a negative pressure space, such as a prescription dispensing apparatus or a microorganism processing apparatus. May be provided.

  As mentioned above, although embodiment of this invention was described with reference to drawings, this invention is not limited to the thing of embodiment shown in figure. Various modifications and variations can be made to the illustrated embodiment within the same range or equivalent range as the present invention.

DESCRIPTION OF SYMBOLS 1 Mixed injection apparatus 10 Vial bottle 11 Syringe 11a Cylinder part 11b Piston part 2A Transfer apparatus 2B Transfer apparatus 3 Mixing process part 4 Mixed injection operation part 41 1st moving part 414 Holding mechanism 42 2nd moving part 424 Holding mechanism 43 3rd moving part 435 Container inclining part 436 Container holding part 44 Support part 45 Rotation drive part 5 Infusion back holding part 6 Infusion back moving part 7 Infusion back inclined part 9 Base 100 Safety cabinet 100a Bottom plate 100b Front end opening 100c Back side vent 100d Rear duct part 100e bottom plate lower duct part 110 door 111 opening and closing window 120 intake duct 120a inlet part 120b outlet part

Claims (1)

In a safety cabinet that can maintain a negative working space,
Before end opening formed on the outside of the working space,
A door for opening and closing the work space;
An opening / closing window provided on the door;
The door has an inlet portion for taking in air flowing into the work space from the opening / closing window and an outlet portion for taking out air taken in from the inlet portion, and when the door is closed, the outlet portion is A safety cabinet, comprising: an intake duct communicating with the front end opening.

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