JP5759890B2 - カチオン性脂質−dna複合体(cldc)の投与による免疫応答の増強 - Google Patents

カチオン性脂質−dna複合体(cldc)の投与による免疫応答の増強 Download PDF

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JP5759890B2
JP5759890B2 JP2011502032A JP2011502032A JP5759890B2 JP 5759890 B2 JP5759890 B2 JP 5759890B2 JP 2011502032 A JP2011502032 A JP 2011502032A JP 2011502032 A JP2011502032 A JP 2011502032A JP 5759890 B2 JP5759890 B2 JP 5759890B2
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cldc
vaccine
administration
cationic lipid
adjuvant
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JP2011515490A5 (cg-RX-API-DMAC7.html
JP2011515490A (ja
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ジェフリー・フェアマン
マーラ・ボーン
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Juvaris Biotherapeutics Inc
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JP2011502032A 2008-03-25 2009-03-25 カチオン性脂質−dna複合体(cldc)の投与による免疫応答の増強 Expired - Fee Related JP5759890B2 (ja)

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US3938108P 2008-03-25 2008-03-25
US61/039,381 2008-03-25
PCT/US2009/038307 WO2009120811A1 (en) 2008-03-25 2009-03-25 Enhancement of an immune response by administration of a cationic lipid-dna complex (cldc)

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JP2011515490A5 JP2011515490A5 (cg-RX-API-DMAC7.html) 2012-05-17
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US (1) US8945590B2 (cg-RX-API-DMAC7.html)
EP (1) EP2257306B1 (cg-RX-API-DMAC7.html)
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BR (1) BRPI0910036B8 (cg-RX-API-DMAC7.html)
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CA2719614C (en) 2008-03-25 2018-05-01 Juvaris Biotherapeutics, Inc. Enhancement of an immune response by administration of a cationic lipid-dna complex (cldc)
US20120064151A1 (en) * 2009-05-14 2012-03-15 Bayer Animal Health Gmbh Enhanced immune response in avian species
US9089537B2 (en) * 2010-02-26 2015-07-28 The Trustees Of The University Of Pennslyvania Subunit vaccines for herpes viruses and methods of use
JP6058550B2 (ja) * 2010-12-22 2017-01-11 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH ウシの種における免疫応答の増強
AU2014292926B2 (en) 2013-07-25 2020-03-05 Exicure Operating Company Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
MX2016010993A (es) 2014-02-28 2017-05-01 Bayer Animal Health Gmbh Plasmidos inmunoestimuladores.
WO2015187966A1 (en) 2014-06-04 2015-12-10 Aurasense Therapeutics, Llc Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications
WO2016081911A2 (en) 2014-11-21 2016-05-26 Northwestern University The sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates
WO2017021266A1 (en) 2015-07-31 2017-02-09 Bayer Animal Health Gmbh Enhanced immune response in porcine species
AU2016304343A1 (en) * 2015-07-31 2018-02-08 Bayer Animal Health Gmbh Enhanced immune response in aquatic species
US11364304B2 (en) 2016-08-25 2022-06-21 Northwestern University Crosslinked micellar spherical nucleic acids
JP6963018B2 (ja) * 2016-10-31 2021-11-05 アイジーン インコーポレイテッドEyegene Inc. 免疫調節剤及びこれを含むワクチン組成物
WO2018201090A1 (en) 2017-04-28 2018-11-01 Exicure, Inc. Synthesis of spherical nucleic acids using lipophilic moieties

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US5534496A (en) * 1992-07-07 1996-07-09 University Of Southern California Methods and compositions to enhance epithelial drug transport
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EP1006999A2 (en) 1997-07-08 2000-06-14 Chiron Corporation Use of submicron oil-in-water emulsions with dna vaccines
DE69837094T2 (de) * 1997-09-05 2007-08-30 The Regents Of The University Of California, Oakland Verwendung von immunerregenden oligonukleotiden zur vorbeugung oder behandlung von asthma
US20030022854A1 (en) * 1998-06-25 2003-01-30 Dow Steven W. Vaccines using nucleic acid-lipid complexes
US6693086B1 (en) * 1998-06-25 2004-02-17 National Jewish Medical And Research Center Systemic immune activation method using nucleic acid-lipid complexes
US20040247662A1 (en) * 1998-06-25 2004-12-09 Dow Steven W. Systemic immune activation method using nucleic acid-lipid complexes
US20050013812A1 (en) * 2003-07-14 2005-01-20 Dow Steven W. Vaccines using pattern recognition receptor-ligand:lipid complexes
US20050181035A1 (en) * 2004-02-17 2005-08-18 Dow Steven W. Systemic immune activation method using non CpG nucleic acids
US20090208781A1 (en) * 2008-02-19 2009-08-20 Skinner George A Method for operating a fuel cell system
US20110111017A1 (en) 2008-02-24 2011-05-12 Government Of The United States Of America,As Rep. By The Secretary,Dept. Of Health And Human Servic Use of immunogenic compositions for the treatment or prevention of pathogen infections
CA2719614C (en) 2008-03-25 2018-05-01 Juvaris Biotherapeutics, Inc. Enhancement of an immune response by administration of a cationic lipid-dna complex (cldc)
US20100137235A1 (en) * 2008-10-15 2010-06-03 Mutual Pharmaceutical Company, Inc. Methods for Concomitant Administration of Colchicine and Macrolide Antibiotics
US20120064151A1 (en) * 2009-05-14 2012-03-15 Bayer Animal Health Gmbh Enhanced immune response in avian species

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JP2011515490A (ja) 2011-05-19
BRPI0910036B1 (pt) 2020-07-21
BRPI0910036A2 (pt) 2015-08-11
EP2257306B1 (en) 2014-05-07
CA2719614A1 (en) 2009-10-01
CA2719614C (en) 2018-05-01
US20090263423A1 (en) 2009-10-22
BRPI0910036B8 (pt) 2021-05-25
US8945590B2 (en) 2015-02-03
EP2257306A1 (en) 2010-12-08

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