JP5753077B2 - 抗菌ペプチド多量体 - Google Patents
抗菌ペプチド多量体 Download PDFInfo
- Publication number
- JP5753077B2 JP5753077B2 JP2011506235A JP2011506235A JP5753077B2 JP 5753077 B2 JP5753077 B2 JP 5753077B2 JP 2011506235 A JP2011506235 A JP 2011506235A JP 2011506235 A JP2011506235 A JP 2011506235A JP 5753077 B2 JP5753077 B2 JP 5753077B2
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- amino acid
- peptide
- multimer
- seq
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Eyeglasses (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| EP2277899B1 (en) * | 2006-04-27 | 2015-07-08 | Singapore Health Services Pte Ltd | Antimicrobial peptides |
| US20110311601A1 (en) * | 2010-06-22 | 2011-12-22 | Michael Kleine | Antimicrobial medical devices |
| CN107652364A (zh) * | 2011-04-02 | 2018-02-02 | 新加坡保健服务集团 | 抗菌肽的多聚体形式 |
| SG11201501388VA (en) * | 2012-09-07 | 2015-03-30 | Agency Of Science Technology And Res | Tetrabranched peptides and analogues as a new class of antimicrobials and their preparation thereof |
| WO2014039014A1 (en) * | 2012-09-07 | 2014-03-13 | Agency For Science, Technology And Research | Peptides and their uses |
| JP6362878B2 (ja) * | 2013-03-12 | 2018-07-25 | 国立研究開発法人農業・食品産業技術総合研究機構 | 改変ペプチド繰り返しペプチドを含む融合タンパク質および該融合タンパク質を含むシルク繊維 |
| WO2015138494A1 (en) | 2014-03-10 | 2015-09-17 | Georges Belfort | Anti-microbial peptides and method for designing novel anti-microbial peptides |
| WO2016081594A1 (en) * | 2014-11-19 | 2016-05-26 | The General Hospital Corporation | System and method for photo-dynamic procedure |
| AU2015396744B2 (en) * | 2015-05-29 | 2020-04-16 | Hexima Limited | A method of in vivo treatment |
| CN106866793B (zh) * | 2015-12-14 | 2022-04-19 | 韩苏 | 一种多肽化合物及其制备方法与应用 |
| US20220133699A1 (en) | 2019-02-14 | 2022-05-05 | Singapore Eye Research Institute | Antibacterial Compositions |
| CN118555963A (zh) * | 2020-10-22 | 2024-08-27 | 香港大学 | 抗病毒肽和/或化合物的组合物及其使用方法 |
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| US5057520A (en) * | 1989-03-24 | 1991-10-15 | Abbott Laboratories | 7-(peptidylpyrolidinyl)naphthyridine antibacterial compounds |
| US5639594A (en) * | 1990-02-16 | 1997-06-17 | United Biomedical, Inc. | Linear and branched peptides effective in diagnosing and detecting non-A, non-B hepatitis |
| US5919761A (en) * | 1992-08-14 | 1999-07-06 | The Board Of Regents Of The University Of Michigan | Peptides for heparin and low molecular weight heparin anticoagulation reversal |
| US8172395B2 (en) | 2002-12-03 | 2012-05-08 | Novartis Ag | Medical devices having antimicrobial coatings thereon |
| GB0514482D0 (en) | 2005-07-14 | 2005-08-17 | Ares Trading Sa | Protein |
| WO2007025178A2 (en) | 2005-08-26 | 2007-03-01 | New York University | Rolyvalent multimeric compositions containing active polypeptides, pharmaceutical compositions and methods of using the same |
| US7531505B2 (en) * | 2006-01-11 | 2009-05-12 | Affinergy, Inc. | Compositions and methods for promoting attachment of cells of endothelial cell lineage to medical devices |
| EP2277899B1 (en) * | 2006-04-27 | 2015-07-08 | Singapore Health Services Pte Ltd | Antimicrobial peptides |
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| JP2015145373A (ja) | 2015-08-13 |
| WO2009131548A8 (en) | 2010-11-25 |
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| EP2853539B1 (en) | 2018-10-10 |
| AU2009238701A1 (en) | 2009-10-29 |
| ZA201007509B (en) | 2013-06-26 |
| WO2009131548A1 (en) | 2009-10-29 |
| EP2279202A4 (en) | 2011-08-31 |
| US8809262B2 (en) | 2014-08-19 |
| JP2011521902A (ja) | 2011-07-28 |
| AU2009238701B2 (en) | 2013-06-20 |
| SG10201406288SA (en) | 2014-12-30 |
| US20110039760A1 (en) | 2011-02-17 |
| EP2853539A1 (en) | 2015-04-01 |
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