JP5685601B2 - ナノ流体バイオセンサ及び溶液中における生体分子の相互作用の迅速測定のためのその活用及び方法 - Google Patents

ナノ流体バイオセンサ及び溶液中における生体分子の相互作用の迅速測定のためのその活用及び方法 Download PDF

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JP5685601B2
JP5685601B2 JP2012540523A JP2012540523A JP5685601B2 JP 5685601 B2 JP5685601 B2 JP 5685601B2 JP 2012540523 A JP2012540523 A JP 2012540523A JP 2012540523 A JP2012540523 A JP 2012540523A JP 5685601 B2 JP5685601 B2 JP 5685601B2
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biomolecule
biosensor
solution
nanoslit
optical
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Japanese (ja)
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JP2013512428A (ja
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ニコラ・デュラン
ヤニック・フルニエ
テオ・ラセ
イワン・マーキ
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Ecole Polytechnique Federale de Lausanne EPFL
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Ecole Polytechnique Federale de Lausanne EPFL
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y35/00Methods or apparatus for measurement or analysis of nanostructures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
JP2012540523A 2009-11-27 2010-11-19 ナノ流体バイオセンサ及び溶液中における生体分子の相互作用の迅速測定のためのその活用及び方法 Active JP5685601B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH01824/09 2009-11-27
CH18242009 2009-11-27
PCT/IB2010/055305 WO2011064701A1 (en) 2009-11-27 2010-11-19 Nanofluidic biosensor and its use for rapid measurement of biomolecular interactions in solution and methods

Publications (2)

Publication Number Publication Date
JP2013512428A JP2013512428A (ja) 2013-04-11
JP5685601B2 true JP5685601B2 (ja) 2015-03-18

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JP2012540523A Active JP5685601B2 (ja) 2009-11-27 2010-11-19 ナノ流体バイオセンサ及び溶液中における生体分子の相互作用の迅速測定のためのその活用及び方法

Country Status (9)

Country Link
US (1) US9452927B2 (zh)
EP (1) EP2504684B1 (zh)
JP (1) JP5685601B2 (zh)
CN (1) CN102762971B (zh)
AU (1) AU2010322751B2 (zh)
BR (1) BR112012012787B1 (zh)
CA (1) CA2782009C (zh)
HK (1) HK1175527A1 (zh)
WO (1) WO2011064701A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2684027B1 (en) 2011-03-09 2019-12-11 Abionic SA Rapid quantification of biomolecules in a selectively functionalized nanofluidic biosensor and method thereof
WO2015007559A1 (en) * 2013-07-17 2015-01-22 Abionic Sa Method and device for bioassays
EP3080589B1 (en) * 2013-12-13 2019-05-22 Abionic SA Gas evacuation system for nanofluidic biosensor
CA2953755C (en) 2014-07-03 2022-05-03 Abionic Sa Capsule for rapid molecular quantification of a fluid sample such as whole blood
JP6880001B2 (ja) 2015-08-28 2021-06-02 ヴェンタナ メディカル システムズ, インク. ケージドハプテンを使用するホルマリン固定パラフィン包埋組織におけるタンパク質近接アッセイ

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5370842A (en) 1991-11-29 1994-12-06 Canon Kabushiki Kaisha Sample measuring device and sample measuring system
JP2832117B2 (ja) * 1991-11-29 1998-12-02 キヤノン株式会社 サンプル測定デバイス及びサンプル測定システム
US6248539B1 (en) * 1997-09-05 2001-06-19 The Scripps Research Institute Porous semiconductor-based optical interferometric sensor
JP4010171B2 (ja) 2001-04-16 2007-11-21 東ソー株式会社 微小流路構造体、その製造方法及びその用途
US7201873B2 (en) 2001-04-16 2007-04-10 Tosoh Corporation Fine channel device, method for producing the fine channel device and use of the same
CA2459570A1 (en) 2001-09-05 2003-03-13 Genicon Sciences Corporation Apparatus for reading signals generated from resonance light scattered particle labels
AU2003248273A1 (en) 2002-07-12 2004-02-02 Mitsubishi Chemical Corporation Analytical chip, analytical chip unit, analyzing apparatus, method of analysis using the apparatus, and method of producing the analytical chip
JP3991034B2 (ja) 2004-01-23 2007-10-17 キヤノン株式会社 検出方法
GB0411162D0 (en) 2004-05-19 2004-06-23 Precisense As Optical sensor for in vivo detection of analyte
US7262859B2 (en) 2004-10-13 2007-08-28 U.S. Genomics, Inc. Systems and methods for measurement optimization
US7405434B2 (en) 2004-11-16 2008-07-29 Cornell Research Foundation, Inc. Quantum dot conjugates in a sub-micrometer fluidic channel
US8945909B2 (en) 2007-04-25 2015-02-03 The Regents Of The University Of Michigan Tunable elastomeric nanochannels for nanofluidic manipulation
US20090214392A1 (en) 2008-02-27 2009-08-27 The Texas A&M University System Nano-fluidic Trapping Device for Surface-Enhanced Raman Spectroscopy
US9810680B2 (en) * 2009-04-16 2017-11-07 Nanonex Corporation Nanogap electronic detector for measuring properties of a biomolecule stretched in a nanochannel, and method thereof

Also Published As

Publication number Publication date
JP2013512428A (ja) 2013-04-11
BR112012012787A2 (pt) 2016-08-16
HK1175527A1 (zh) 2013-07-05
CA2782009A1 (en) 2011-06-03
EP2504684C0 (en) 2023-11-15
BR112012012787B1 (pt) 2019-12-17
AU2010322751A1 (en) 2012-06-21
CN102762971B (zh) 2015-05-27
CA2782009C (en) 2017-10-03
US20130017967A1 (en) 2013-01-17
AU2010322751B2 (en) 2014-05-29
US9452927B2 (en) 2016-09-27
CN102762971A (zh) 2012-10-31
EP2504684B1 (en) 2023-11-15
WO2011064701A1 (en) 2011-06-03
EP2504684A1 (en) 2012-10-03

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