JP5638958B2 - ウイルス性肝炎におけるsLDLR - Google Patents

ウイルス性肝炎におけるsLDLR Download PDF

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Publication number
JP5638958B2
JP5638958B2 JP2010541140A JP2010541140A JP5638958B2 JP 5638958 B2 JP5638958 B2 JP 5638958B2 JP 2010541140 A JP2010541140 A JP 2010541140A JP 2010541140 A JP2010541140 A JP 2010541140A JP 5638958 B2 JP5638958 B2 JP 5638958B2
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JP
Japan
Prior art keywords
sldlr
use according
body weight
hbv
cells
Prior art date
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Expired - Fee Related
Application number
JP2010541140A
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English (en)
Japanese (ja)
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JP2011509254A5 (https=
JP2011509254A (ja
Inventor
ルビンステイン、メナケム
ウェルマン、アリール
アルカヘ、ベン
Original Assignee
イエダ リサーチ アンド ディベロップメント カンパニー リミテッド
イエダ リサーチ アンド ディベロップメント カンパニー リミテッド
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Publication of JP2011509254A publication Critical patent/JP2011509254A/ja
Publication of JP2011509254A5 publication Critical patent/JP2011509254A5/ja
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2010541140A 2008-01-07 2009-01-07 ウイルス性肝炎におけるsLDLR Expired - Fee Related JP5638958B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL188628A IL188628A0 (en) 2008-01-07 2008-01-07 Use of soluble ldl-r for viral hepatitis
IL188628 2008-01-07
PCT/IL2009/000023 WO2009087622A2 (en) 2008-01-07 2009-01-07 Sldlr in viral hepatitis

Publications (3)

Publication Number Publication Date
JP2011509254A JP2011509254A (ja) 2011-03-24
JP2011509254A5 JP2011509254A5 (https=) 2013-11-21
JP5638958B2 true JP5638958B2 (ja) 2014-12-10

Family

ID=40691055

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010541140A Expired - Fee Related JP5638958B2 (ja) 2008-01-07 2009-01-07 ウイルス性肝炎におけるsLDLR

Country Status (7)

Country Link
US (1) US8293706B2 (https=)
EP (1) EP2229179B1 (https=)
JP (1) JP5638958B2 (https=)
CA (1) CA2710664A1 (https=)
ES (1) ES2400743T3 (https=)
IL (2) IL188628A0 (https=)
WO (1) WO2009087622A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014160088A2 (en) * 2013-03-14 2014-10-02 Rhode Island Hospital, A Lifespan-Partner Treating hepatitis b virus infections
IL298166A (en) * 2020-05-14 2023-01-01 Nutcracker Therapeutics Inc Polynucleotides comprising an antigenic payload
US20260053948A1 (en) * 2022-09-15 2026-02-26 Yeda Research And Development Co. Ltd. Compositions and methods for virotherapy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL102915A (en) 1992-01-19 2005-12-18 Yeda Res & Dev Soluble ldl receptor and its preparation
US5496926A (en) * 1992-01-19 1996-03-05 Yeda Research And Development Co. Ltd. Process of preparing a soluble LDL receptor
WO1999038524A2 (en) * 1998-01-29 1999-08-05 Patrick Thomas Prendergast Therapeutic administration of low density lipoprotein receptor for viral infections and immune regulation
IL139217A0 (en) * 2000-03-13 2001-11-25 Applied Research Systems Monoclonal antibodies to the human ldl receptor, their production and use
EP1592445A4 (en) * 2000-10-25 2007-01-10 Vincent Agnello METHOD FOR INHIBITING HEPATITIS C VIRUS (HCV) INFECTION AND OTHER FLAVIRIDAE / I FAMILY VIRUSES, AND OTHER BLOODY-VIRUSES COMPLEXING WITH LOW OR VERY LOW DENSITY LIPOPROTEIN DENSITY, BY PREVENTING VIRAL ENTRY IN A CELL

Also Published As

Publication number Publication date
ES2400743T3 (es) 2013-04-11
IL206691A0 (en) 2010-12-30
US20100279928A1 (en) 2010-11-04
IL188628A0 (en) 2008-12-29
AU2009203518A1 (en) 2009-07-16
JP2011509254A (ja) 2011-03-24
EP2229179B1 (en) 2013-02-27
EP2229179A2 (en) 2010-09-22
IL206691A (en) 2013-07-31
WO2009087622A3 (en) 2010-03-18
CA2710664A1 (en) 2009-07-16
US8293706B2 (en) 2012-10-23
WO2009087622A2 (en) 2009-07-16

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