JP5615694B2 - 186レニウムを単離する方法 - Google Patents
186レニウムを単離する方法 Download PDFInfo
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- JP5615694B2 JP5615694B2 JP2010501607A JP2010501607A JP5615694B2 JP 5615694 B2 JP5615694 B2 JP 5615694B2 JP 2010501607 A JP2010501607 A JP 2010501607A JP 2010501607 A JP2010501607 A JP 2010501607A JP 5615694 B2 JP5615694 B2 JP 5615694B2
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- JP
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- Prior art keywords
- isolating
- negatively charged
- charged molecule
- source compound
- vaporized
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G47/00—Compounds of rhenium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D59/00—Separation of different isotopes of the same chemical element
- B01D59/44—Separation by mass spectrography
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G39/00—Compounds of molybdenum
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2006/00—Physical properties of inorganic compounds
- C01P2006/88—Isotope composition differing from the natural occurrence
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Electron Sources, Ion Sources (AREA)
Description
185Re(n,γ)186Re (1)
上記式において、185Reは反応器での中性子捕獲により186Reへと変換される。この方法による生産量は比較的高いものの、目的の186Re同位元素を原料物質から分離する(たとえば化学的分離によって)のは困難であり、得られる産物は比較的低い比放射能を示すことになる。
186W(p,n)186Re (2)
上記式において、186Wは粒子加速器内での陽子入射反応により186Reへと変換される。この方法による生産量は比較的低いものの、目的の186Re同位元素を原料物質から分離する(たとえば化学的分離によって)のはより簡単であり、得られる産物の比放射能のレベルは改善されている。
Claims (13)
185Reと186Reを含む源化合物を気化する工程と、
上記気化された源化合物をイオン化して、185Reと186Reを含む負の電荷を帯びた分子にする工程と、
上記負の電荷を帯びた分子を分離して、186Reを含む負の電荷を帯びた分子を単離する工程と、
上記単離された186Reを含む負の電荷を帯びた分子を、正の電荷を帯びた収集器によって収集する工程と、
を含む方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90943107P | 2007-03-31 | 2007-03-31 | |
US60/909,431 | 2007-03-31 | ||
PCT/IB2008/000761 WO2008120084A2 (en) | 2007-03-31 | 2008-03-31 | Method and apparatus for isolating 186rhenium |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010531719A JP2010531719A (ja) | 2010-09-30 |
JP5615694B2 true JP5615694B2 (ja) | 2014-10-29 |
Family
ID=39794717
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010501607A Expired - Fee Related JP5615694B2 (ja) | 2007-03-31 | 2008-03-31 | 186レニウムを単離する方法 |
Country Status (6)
Country | Link |
---|---|
US (2) | US7708961B2 (ja) |
EP (1) | EP2142284A4 (ja) |
JP (1) | JP5615694B2 (ja) |
AU (1) | AU2008234598B2 (ja) |
CA (1) | CA2682383C (ja) |
WO (1) | WO2008120084A2 (ja) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9587292B2 (en) * | 2009-10-01 | 2017-03-07 | Advanced Applied Physics Solutions, Inc. | Method and apparatus for isolating the radioisotope molybdenum-99 |
US9336916B2 (en) | 2010-05-14 | 2016-05-10 | Tcnet, Llc | Tc-99m produced by proton irradiation of a fluid target system |
US9269467B2 (en) | 2011-06-02 | 2016-02-23 | Nigel Raymond Stevenson | General radioisotope production method employing PET-style target systems |
DE102016119239A1 (de) | 2016-10-10 | 2018-04-12 | Oncobeta International Gmbh | Partikel und Zusammensetzung, die Rheniumverbindungen umfassen, und Prozesse zum Erhalten solcher Produkte |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3432709A (en) | 1965-10-23 | 1969-03-11 | Atomic Energy Commission | Calutron ion source with magnetic field inducing coil within arc chamber |
DE2037030C1 (de) | 1970-07-25 | 1975-08-07 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen | Einrichtung zur Trennung von Isotopen durch Zentrifugalkräfte |
US4035270A (en) | 1975-04-23 | 1977-07-12 | Exxon Research And Engineering Company | Isotope separation process |
US4024217A (en) * | 1975-05-23 | 1977-05-17 | The United States Of America As Represented By The United States Energy Research And Development Administration | Method of isotope separation by chemi-ionization |
US4105746A (en) * | 1977-02-07 | 1978-08-08 | The United States Of America As Represented By The United States Department Of Energy | Method and apparatus for providing negative ions of actinide-metal hexafluorides |
JPS59197342A (ja) * | 1983-04-23 | 1984-11-08 | Toto Ltd | 鋳物製品の造型用パタ−ン |
JPH03262518A (ja) * | 1990-03-12 | 1991-11-22 | Toshiba Corp | 同位体分離装置 |
JPH0471623A (ja) | 1990-07-09 | 1992-03-06 | Toshiba Corp | 同位体分離装置 |
JPH0789520B2 (ja) * | 1991-08-26 | 1995-09-27 | ティアールダブリュー インコーポレーテッド | 磁界内に電気的に中性で、密度の均一なプラズマの連続流をつくる方法 |
US5204530A (en) * | 1991-12-27 | 1993-04-20 | Philippe Chastagner | Noise reduction in negative-ion quadrupole mass spectrometry |
FR2705584B1 (fr) * | 1993-05-26 | 1995-06-30 | Commissariat Energie Atomique | Dispositif de séparation isotopique par résonance cyclotronique ionique. |
JPH07116477A (ja) * | 1993-10-21 | 1995-05-09 | Laser Noshuku Gijutsu Kenkyu Kumiai | 同位体分離装置 |
GB9502169D0 (en) * | 1995-02-03 | 1995-03-29 | British Nuclear Fuels Plc | Isotope separation |
US5784423A (en) | 1995-09-08 | 1998-07-21 | Massachusetts Institute Of Technology | Method of producing molybdenum-99 |
US6232709B1 (en) | 1998-10-23 | 2001-05-15 | Michael W. Retsky | Method and apparatus for deflecting and focusing a charged particle stream |
US5862193A (en) * | 1997-08-20 | 1999-01-19 | The Curators Of The University Of Missouri | Production of 186 Re, 188 Re and other radionuclides via inorganic szilard-chalmers process |
US5802439A (en) | 1997-02-19 | 1998-09-01 | Lockheed Martin Idaho Technologies Company | Method for the production of 99m Tc compositions from 99 Mo-containing materials |
JP2002510656A (ja) * | 1998-04-03 | 2002-04-09 | デュポン ファーマシューティカルズ カンパニー | 放射性薬物デリバリーシステム用無機物質 |
RU2158167C1 (ru) * | 1999-10-07 | 2000-10-27 | Комбинат "Электрохимприбор" | Способ разделения изотопов рения в электромагнитном сепараторе с использованием источника ионов |
KR100876482B1 (ko) | 2000-10-17 | 2008-12-31 | 사빅 이노베이티브 플라스틱스 아이피 비.브이. | 반투명 및 투명 폴리카보네이트 열가소성 수지합금 및 그제조방법 |
FR2832408B1 (fr) * | 2001-11-20 | 2005-07-15 | Schering Ag | Complexes de technetium ou de rhenium, produits radiopharmaceutiques les contenant et leur preparation |
KR100439962B1 (ko) * | 2002-06-05 | 2004-07-12 | 한국원자력연구소 | 방사성 의약품용 테크네튬 또는 레늄 착물의 제조방법 |
US20070166227A1 (en) | 2004-02-10 | 2007-07-19 | Shuang Liu | Crowned dithiocarbamate metal complexes and methods for their use |
US20060023829A1 (en) * | 2004-08-02 | 2006-02-02 | Battelle Memorial Institute | Medical radioisotopes and methods for producing the same |
US7439498B2 (en) * | 2004-10-28 | 2008-10-21 | Albert Edward Litherland | Method and apparatus for separation of isobaric interferences |
US9202600B2 (en) | 2005-01-14 | 2015-12-01 | Paul Scherrer Institut | Method for production of radioisotope preparations and their use in life science, research, medical application and industry |
-
2008
- 2008-03-31 EP EP08737360.1A patent/EP2142284A4/en not_active Withdrawn
- 2008-03-31 JP JP2010501607A patent/JP5615694B2/ja not_active Expired - Fee Related
- 2008-03-31 US US12/078,409 patent/US7708961B2/en not_active Expired - Fee Related
- 2008-03-31 WO PCT/IB2008/000761 patent/WO2008120084A2/en active Application Filing
- 2008-03-31 CA CA2682383A patent/CA2682383C/en not_active Expired - Fee Related
- 2008-03-31 AU AU2008234598A patent/AU2008234598B2/en not_active Ceased
-
2010
- 2010-02-26 US US12/659,167 patent/US8211390B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2008120084A3 (en) | 2013-07-18 |
JP2010531719A (ja) | 2010-09-30 |
US7708961B2 (en) | 2010-05-04 |
US20100160614A1 (en) | 2010-06-24 |
WO2008120084A2 (en) | 2008-10-09 |
EP2142284A2 (en) | 2010-01-13 |
US20080241025A1 (en) | 2008-10-02 |
EP2142284A4 (en) | 2015-12-23 |
AU2008234598B2 (en) | 2012-11-29 |
CA2682383C (en) | 2015-03-17 |
US8211390B2 (en) | 2012-07-03 |
CA2682383A1 (en) | 2008-10-09 |
AU2008234598A1 (en) | 2008-10-09 |
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