JP5605181B2 - Manufacturing method of plastic ampule for chemical liquid and plastic ampule for chemical liquid - Google Patents

Description

  The present invention relates to a method for producing a plastic ampule for chemical liquid containing a chemical liquid and a plastic ampule for chemical liquid.

  Conventionally, plastic ampules that contain liquids are molded to suit each application, such as those that contain liquid fertilizer (see Patent Document 1) and those that contain medical chemicals (see Patent Document 2). There are many ampoules.

  For example, a liquid fertilizer plastic ampoule that contains liquid fertilizer includes a bottomed cylindrical main body and a neck that is reduced in diameter from the main body. This plastic fertilizer for liquid fertilizer is manufactured through a molding process for molding the main body and neck by a synthetic resin material, an injection process for injecting liquid fertilizer after the molding process, and a closing process for closing the neck.

  Further, as shown in FIGS. 6 (a) and 6 (b), the plastic ampule for medical liquid that stores medical chemical liquid is provided in the chemical liquid storage section 2a for storing the chemical liquid 5 and the chemical liquid storage section 2a. A chemical solution discharge cylinder portion 3a that communicates with and extends from the chemical solution storage portion 2a and has a closed end is provided, and a gripping piece 4a that is connected to the distal end side of the chemical solution discharge tube portion 3a. The chemical liquid discharge cylinder part 3a includes a cutting auxiliary part 33a formed over the entire circumference in the circumferential direction so as to be cut when opened.

  The plastic ampule 1a for chemicals having such a structure is formed by sandwiching a resin molded product (generally referred to as “parison”), which is molded into a tubular shape with a thermoplastic resin, between a pair of first split molds. A first molding step for molding a part of the chemical solution storage portion 2a and the chemical solution discharge cylinder portion 3a, a chemical solution storage step for storing the chemical solution 5 inside the chemical solution storage portion 2a, and the remaining resin moldings are a pair of second parts. It is manufactured through a second molding step in which the remaining chemical solution discharge cylinder 3a and the gripping piece 4a are molded by being sandwiched between split molds.

  By using this manufacturing method, in the chemical ampule 1a for chemical liquid, the chemical liquid 5 is sealed in an internal space defined by the chemical liquid storage part 2a and the chemical liquid discharge cylinder part 3a. And when using the chemical | medical solution 5, the plastic ampule 1a for chemical | medical solutions can be cut | disconnected and opened this chemical | medical solution discharge cylinder part 3a by bending or twisting the chemical | medical solution discharge cylinder part 3a with the cutting auxiliary | assistant part 33a. Thus, the plastic ampule 1a for chemical | medical solution inserts the nozzle (injection needle) of a syringe into the chemical | medical solution storage part 2a from the opened front-end | tip part of the chemical | medical solution discharge cylinder part 3a, and the chemical | medical solution 5 is a syringe ( Sucked into a syringe).

JP-A-9-238525 JP 2008-104868 A

  By the way, as for the conventional plastic ampule 1a for chemical | medical solutions, the cutting assistance part 33a of the chemical | medical solution discharge cylinder part 3a is shape | molded by the 2nd shaping | molding process after a 1st shaping | molding process. Specifically, the chemical liquid discharge cylinder portion 3a is formed on the proximal end side (lower side) of the cutting assisting portion 33a in the first molding step, and on the distal end side (upper side) including the cutting assisting portion 33a in the second molding step. ) Is molded. That is, the chemical ampule 1a for chemicals is a second that corresponds to the boundary between the part molded by the first split mold and the part molded by the second split mold as shown in FIGS. 6 (c) and 6 (d). 1 boundary position P1a is manufactured so that it may be located in the base end side rather than cutting auxiliary part 33a. Therefore, the chemical | medical solution discharge cylinder part 3a shape | molds the part of the front end side from the 1st boundary position P1a, after hardening the part of the base end side from the 1st boundary position P1a. As described above, in the chemical liquid discharge cylinder portion 3a, the timing at which the resin is cured differs between the portion molded by the first split mold and the portion molded by the second split mold.

  For this reason, when the resin molding used in the second molding step exceeds the amount necessary for molding the remaining chemical liquid discharge cylinder portion 3a, the excess resin loses its place, and the chemical liquid discharge cylinder portion 3a Is a resin that swells above the boundary portion (the first boundary position P1a) between the portion molded by the first split mold and the portion molded by the second split mold (the portion molded by the second split mold). A pool 35a may be formed.

  The resin reservoir 35a is formed from the first boundary position P1a to the distal end side of the chemical liquid discharge cylinder portion 3a, and particularly, is formed in the immediate vicinity of the first boundary position P1a. The opening for inserting a nozzle is narrowed by this resin reservoir 35a in the chemical | medical solution discharge cylinder part 3a. Further, since the resin reservoir 35a is formed closer to the chemical solution storage portion 2a than the cutting auxiliary portion 33a, even if the chemical discharge tube portion 3a is cut by the cutting auxiliary portion 33a, the nozzle is stored in the chemical solution discharge tube portion 3a. It remains on the path to be inserted into the portion 2a and hinders the insertion of the nozzle. Since such a plastic ampule 1a for chemicals cannot be used, it is treated as a nonconforming product, which causes a reduction in yield.

  Therefore, in view of such circumstances, the present invention can be handled as a conforming product that does not hinder the quality in its usage state even when a resin reservoir is formed in the chemical solution discharge cylinder, and can increase the yield. An object of the present invention is to provide a method for producing a plastic ampule for chemical liquid and a plastic ampule for chemical liquid produced by the production method.

A method for producing a plastic ampule for a chemical solution according to the present invention includes a chemical solution storage portion for storing a chemical solution, and a chemical solution discharge tube portion that communicates with the chemical solution storage portion and extends from the chemical solution storage portion to close the tip. , obtain Preparations and drug solution discharge tube having a cutting assistance part formed over the entire circumference in order to cut upon opening, and a grip piece projecting from the front end side portion than the auxiliary cutting part of the drug solution discharge tube A method for producing a plastic ampule for a chemical solution, wherein a part of a resin molded product, which is molded into a cylindrical shape with a thermoplastic resin and heated, is sandwiched from both sides in a radial direction by a pair of first split molds, and a chemical solution storage portion and a cutting aid A first molding step for integrally molding a part of the chemical solution discharge cylinder including the portion and a part of the grip piece, and a chemical solution storage step for storing the chemical solution inside the chemical solution storage portion formed by the pair of first split molds And a pair of resin moldings Sandwiching the both sides in the radial direction by two split mold, and a second forming step of forming the remainder of the drug solution discharge tube and the rest of the gripping piece, the first mold part and the second mold part of a pair of the pair, said pair The pair of first split molds and the pair of second split molds overlap with each other so that the mating surfaces of the first split molds overlap with each other and the mating surfaces of the pair of second split molds overlap with each other. when it is a feature that you have been configured to position the gripping piece portion of the resin molded product to be molded in contact to the respective second mold part and a pair each of first mold part of a pair To do.

  According to this method, the first boundary position serving as the boundary between the portion of the chemical liquid discharge cylinder portion molded by the first split mold and the portion of the chemical liquid discharge cylinder portion molded by the second split mold is more distal than the cutting auxiliary portion. Side (upper side). That is, the cutting auxiliary part of the plastic ampule for chemical liquid is positioned on the base end side (lower side) from the first boundary position, and is molded by the first split mold in the first molding step. And since the resin reservoir is formed on the tip side (upper end side) from the first boundary position in the second molding step, the plastic ampule for chemicals manufactured by this method has the cutting auxiliary portion more than the resin reservoir. Provide on the proximal side.

  Therefore, even if a resin reservoir is formed in the chemical discharge cylinder part during the manufacturing process, the resin reservoir is formed when the chemical discharge cylinder part is cut and opened by the cutting assisting part. Since the chemical solution discharge cylinder part is removed together with a part of the chemical solution discharge cylinder part and the remaining chemical solution discharge cylinder part, the unsealed chemical solution discharge cylinder part does not leave a resin reservoir that hinders the insertion of the nozzle. . Therefore, even when a resin reservoir is formed in the chemical solution discharge cylinder, it can be handled as a conforming product that does not hinder the quality in the usage state, and the yield can be increased.

In addition , the gripping piece to be gripped when cutting and opening the chemical solution discharge cylinder portion with the cutting assisting portion can be formed simultaneously with the formation of the chemical solution discharge cylinder portion.

Furthermore , a part of the heated resin molding is formed by being sandwiched from both sides in the radial direction at the boundary between the pair of first split molds and the boundary between the pair of second split molds. The gripping piece formed in this way is provided so as to include a second boundary position that is a part corresponding to the boundary between the pair of first split molds and that is a part corresponding to the boundary between the pair of second split molds. . Further, the gripping piece includes a first boundary position that is a portion corresponding to a portion where the surface formed perpendicular to the boundary of the first split mold and the surface formed perpendicular to the boundary of the second split mold are in close contact with each other. It is provided as follows. At the position where the first boundary position and the second boundary position of the gripping piece intersect with each other, it is difficult to apply a force from each split mold, which may result in molding failure. Therefore, an opening is easily formed at this position.

  However, even if a part of the gripping piece formed away from the chemical solution discharge cylinder part is locally opened during the manufacturing process, the chemical solution is blocked by the chemical solution discharge cylinder part. The opening of the piece is not communicated with the chemical solution discharge cylinder. Therefore, the chemical liquid stored in the chemical liquid storage portion does not leak to the outside through the opening of the gripping piece. Further, the chemical solution storage portion and the chemical solution discharge cylinder portion are not formed by arranging the gripping piece at a position where such an opening is easily formed. Therefore, even when a part of the gripping piece is locally opened, it can be handled as a compatible product that does not hinder the quality in the usage state, and the yield can be increased.

The plastic ampule for medicinal solution according to the present invention is a medicinal solution containing portion for containing medicinal solution, and a medicinal solution discharge tube portion communicating with the medicinal solution containing portion and extending from the medicinal solution containing portion to close the tip , a drug solution discharge tube having a cutting assistance part formed over the entire circumference in order to cut the time of unsealing, Bei obtain chemical and holding pieces projecting from the tip portion from the auxiliary cutting part of the drug solution discharge tube A pair of first split molds and the pair of first split molds in a state where a pair of first split molds overlap with each other and a pair of second split molds overlap with each other. Constructed so that when the second split mold is overlaid, the gripping piece is positioned at the portion of the resin molded product that is molded in contact with each of the pair of first split molds and each of the pair of second split molds. A pair of second Using split mold and the pair of second mold part is shaped into a cylindrical shape by a thermoplastic resin, in the first split mold portions of the remaining of the resin molded product of the pair, leaving a portion of the heated resin molded product sandwiching the both sides in the radial direction, a first forming step you forming a portion of the part and the gripping pieces of the drug solution discharge tube comprising a cutting assistance part drug solution storage part integrally molded in the first mold part of a pair A chemical solution storage step for storing a chemical solution inside the chemical solution storage portion, and a pair of second split molds sandwiching the remaining resin molded product from both sides in the radial direction , and molding the remaining chemical solution discharge cylinder portion and the remaining gripping piece produced by second molding step of characterized by Rukoto.

  According to such a configuration, the first boundary position serving as the boundary between the portion of the chemical liquid discharge cylinder portion molded by the first split mold and the portion of the chemical liquid discharge cylinder portion molded by the second split mold is more distal than the cutting auxiliary portion. Side (upper side). That is, the cutting auxiliary part of the plastic ampule for chemical liquid is positioned on the base end side (lower side) from the first boundary position, and is molded by the first split mold in the first molding step. And since the resin reservoir is formed on the tip side (upper end side) from the first boundary position in the second molding step, the plastic ampule for chemicals manufactured by this method has the cutting auxiliary portion more than the resin reservoir. Provide on the proximal side.

Therefore, even if a resin reservoir is formed in the chemical discharge cylinder part during the manufacturing process, the resin reservoir is formed when the chemical discharge cylinder part is cut and opened by the cutting assisting part. Since the chemical solution discharge cylinder part is removed together with a part of the chemical solution discharge cylinder part and the remaining chemical solution discharge cylinder part, the unsealed chemical solution discharge cylinder part does not leave a resin reservoir that hinders the insertion of the nozzle. . Therefore, even when a resin reservoir is formed in the chemical solution discharge cylinder, it can be handled as a conforming product that does not hinder the quality in the usage state, and the yield can be increased.
In addition, the gripping piece to be gripped when cutting and opening the chemical solution discharge cylinder portion with the cutting assisting portion can be formed simultaneously with the formation of the chemical solution discharge cylinder portion.
Furthermore, a part of the heated resin molding is formed by being sandwiched from both sides in the radial direction at the boundary between the pair of first split molds and the boundary between the pair of second split molds. The gripping piece formed in this way is provided so as to include a second boundary position that is a part corresponding to the boundary between the pair of first split molds and that is a part corresponding to the boundary between the pair of second split molds. . Further, the gripping piece includes a first boundary position that is a portion corresponding to a portion where the surface formed perpendicular to the boundary of the first split mold and the surface formed perpendicular to the boundary of the second split mold are in close contact with each other. It is provided as follows. At the position where the first boundary position and the second boundary position of the gripping piece intersect with each other, it is difficult to apply a force from each split mold, which may result in molding failure. Therefore, an opening is easily formed at this position.
However, even if a part of the gripping piece formed away from the chemical solution discharge cylinder part is locally opened during the manufacturing process, the chemical solution is blocked by the chemical solution discharge cylinder part. The opening of the piece is not communicated with the chemical solution discharge cylinder. Therefore, the chemical liquid stored in the chemical liquid storage portion does not leak to the outside through the opening of the gripping piece. Further, the chemical solution storage portion and the chemical solution discharge cylinder portion are not formed by arranging the gripping piece at a position where such an opening is easily formed. Therefore, even when a part of the gripping piece is locally opened, it can be handled as a compatible product that does not hinder the quality in the usage state, and the yield can be increased.

  As described above, according to the method for manufacturing a plastic ampule for chemical liquid and the plastic ampule for chemical liquid according to the present invention, even when a resin reservoir is formed in the chemical liquid discharge tube portion, there is no problem in quality in the usage state. It can be handled as a conforming product and has an excellent effect of increasing the yield.

It is the plastic ampule for chemical | medical solution of one Embodiment which concerns on this invention, Comprising: (a) shows the external view seen from the front, (b) expands the part which the holding piece of (a) opened locally (C) shows a cross-sectional view taken along line AA in (a), and (d) shows an enlarged view of the resin reservoir in the chemical solution discharge cylinder part in (c). FIG. Sectional drawing of the split mold (1st split mold and 2nd split mold) used for manufacture of the plastic ampule for chemical | medical solutions of the embodiment is shown. It is a manufacturing process of the plastic ampule for chemical | medical solutions of the embodiment, Comprising: (a) shows a parison injection process, (b) shows a parison holding process. It is a manufacturing process of the plastic ampule for chemical | medical solution of the embodiment, Comprising: (a) shows a 1st shaping | molding process, (b) shows a chemical | medical solution accommodation process. It is a manufacturing process of the plastic ampule for chemical | medical solutions of the embodiment, Comprising: (a) shows a 2nd shaping | molding process, (b) shows a split mold open process. It is the conventional plastic ampule for chemical | medical solution, Comprising: (a) shows the external view seen from the front, (b) is the principal part enlarged view to which the part which the holding piece of (a) opened locally is expanded. (C) shows sectional drawing cut | disconnected by arrow AA of (a), (d) shows the principal part enlarged view to which the resin reservoir of the chemical | medical solution discharge cylinder part of (c) was expanded.

  Hereinafter, a plastic ampule for chemical liquid according to an embodiment of the present invention (hereinafter simply referred to as an ampule) will be described with reference to the accompanying drawings.

  First, the configuration of the ampoule according to the present embodiment will be described with reference to FIG. This ampoule 1 is manufactured for the purpose of keeping the inside of a container aseptic and stably storing and storing the chemical liquid by sealing the chemical liquid in the container. The ampoule 1 is appropriately selected from materials according to the properties of the medicine to be stored. Further, the ampoule 1 may have a multilayer structure further including one or more layers according to the properties of the drug.

  As shown in FIGS. 1A and 1B, an ampoule 1 according to the present embodiment communicates with a chemical solution storage unit 2 for storing a chemical solution 5 and the chemical solution storage unit 2 and also stores the chemical solution storage unit. 2 is provided with a chemical solution discharge cylinder portion 3 extending from 2 and closing the tip, and a gripping piece 4 connected to the tip end side of the chemical solution discharge tube portion 3.

  The chemical solution storage unit 2 includes a cylindrical storage unit main body 21 that stores the chemical solution 5, and a bottom 22 that closes the base end side (lower side) of the storage unit main body 21.

  As shown in FIGS. 1 (c) and 1 (d), the chemical liquid discharge cylinder portion 3 is inserted into the cylindrical main body 31 and a cylindrical cylindrical main body 31 formed in communication with the chemical liquid storage portion 2. A nozzle fixing portion 32 for fixing the position of the nozzle of the syringe to be positioned, a cutting auxiliary portion 33 that is cut over the entire circumference in the circumferential direction at the time of opening, and a closing portion 34 that closes the tip of the cylindrical portion main body 31 Is provided.

  The nozzle fixing portion 32 has a shape that matches the outer shape of the nozzle so that the nozzle can be fixed at a predetermined position by closely contacting the nozzle of the syringe. In the nozzle assumed to be fixed by the nozzle fixing portion 32 according to the present embodiment, the tip is assumed to be inserted from the bottom portion 22 of the chemical solution storage portion 2 to a predetermined height (position). The base end portion of the nozzle is formed with a diameter increasing from the front end side toward the base end. Therefore, the nozzle fixing portion 32 is provided at the position of the base end portion of the nozzle when the tip end of the nozzle reaches a position separated from the bottom portion 22 of the chemical solution storage portion 2 by a predetermined height, and has the same diameter as the base end portion of the nozzle. Has been expanded. The nozzle fixing portion 32 is configured so that the chemical liquid storage nozzle of the cylindrical chemical liquid storage means for storing the chemical liquid 5 in the chemical liquid storage portion 2 can be fixed in the same manner as the nozzle of the syringe.

  The cutting auxiliary part 33 is formed to be recessed inward over the entire circumference in the circumferential direction. The cutting assisting part 33 is provided for concentrating the stress by bending or twisting the gripping piece 4 with respect to the chemical liquid storage part 2 and separating the lower chemical liquid storage part 2 from the upper gripping piece 4. Yes. Further, the chemical liquid discharge cylinder portion 3 serves as a passage through which the chemical liquid storage nozzle passes, and also serves as a passage through which the nozzle of the syringe passes in order to suck the chemical liquid 5 when the chemical liquid is used. The cutting assisting portion 33 is formed between the chemical solution storage nozzle and the nozzle fixing portion 32 formed at the proximal end portion of the chemical liquid discharge cylinder portion 3 from the tip of the chemical liquid discharge cylinder portion 3 that corresponds to the inlet of the nozzle passage. The Therefore, the cutting assisting portion 33 is configured so as not to interfere with the passage of the chemical solution storage nozzle inserted into the nozzle fixing portion 32 and the nozzle. In other words, the cutting assisting portion 33 is provided outside the portion of the nozzle fixing portion 32 having the largest diameter (is located outside by α) and does not protrude inward.

  The closing part 34 seals the internal space defined by the chemical liquid storage part 2 and the chemical liquid discharge cylinder part 3 communicating with the chemical liquid storage part 2. Therefore, the closing part 34 partitions the internal space and the outside, and is also a part that partitions the internal space and the gripping piece 4.

  As shown in FIGS. 1 (a) and 1 (c), the gripping piece 4 includes side gripping portions 41 and 41 projecting from both ends of the distal end side of the cutting assisting portion 33 of the chemical solution discharge cylinder portion 3, and the side gripping. And a tip gripping portion 42 that is formed continuously from the portions 41 and 41 and projects from the tip side of the chemical liquid discharge tube portion 3. In the gripping piece 41, the part below the tip of the chemical liquid discharge cylinder part 3 is the side gripping parts 41, 41, and the part above the tip of the chemical liquid discharge cylinder part 3 is the tip gripping part 42.

  Next, a method for manufacturing the ampoule 1 according to the present embodiment will be described with reference to FIGS. First, the split mold used for manufacturing the ampoule 1 according to the present embodiment will be described with reference to FIG.

  In the ampoule 1 according to this embodiment, a chemical solution 5 is sealed in an internal space defined by a chemical solution storage portion 2 and a chemical solution discharge cylinder portion 3 communicating with the chemical solution storage portion 2. Therefore, the manufacturing process includes a first molding process for molding the chemical liquid storage part 2 and the chemical liquid discharge cylinder part 3 including the nozzle fixing part 32 for fixing the chemical liquid storage nozzle or the nozzle of the syringe, and the outside is left open to the outside. After the chemical liquid 5 is stored in the chemical liquid storage part 2 from the chemical liquid discharge cylinder part 3, it is molded separately from the second molding step for closing the chemical liquid discharge cylinder part 3.

  Therefore, the split mold used for manufacturing the ampoule 1 according to the present embodiment is divided into the first split molds 61 and 61 used in the first molding process and the second split molds 62 and 62 used in the second molding process. . The first split molds 61 and 61 are disposed on the lower side, and the second split molds 62 and 62 are disposed on the upper side of the first split molds 61 and 61.

  The pair of first split molds 61 and 61 are arranged so that the planar mating surfaces formed in the concave molds are opposed to each other, and are provided so as to be movable relative to each other. The first split molds 61, 61 are molds for molding the chemical liquid storage part 2, a part of the chemical liquid discharge cylinder part 3 including the cutting auxiliary part 33, and a part of the gripping piece 4. Therefore, when the first split molds 61 and 61 are brought into close contact with each other, the concave molds are combined to form the molding space S. The molding space S is formed so as to correspond to the outer shapes of the chemical liquid storage part 2 to be molded in the first molding step, a part of the chemical liquid discharge cylinder part 3 including the cutting auxiliary part 33, and a part of the grip piece 4. Is done. A part of the chemical solution discharge cylinder portion 3 formed in the molding space S includes a base end side cylinder portion body 31 including at least the cutting auxiliary portion 33, a nozzle fixing portion 32, and a cutting auxiliary portion 33. The part of the grip piece 4 molded in the molding space S is a part of the side grip part 41.

  The pair of second split molds 62 and 62 are arranged so that the planar mating surfaces formed in the concave molds are opposed to each other, and are provided so as to be relatively movable so as to be able to contact and separate. The second split molds 62 and 62 are molds for molding the remaining chemical solution discharge cylinder portion 3 and the remaining gripping piece 4 that were not formed by the first split molds 61 and 61. Therefore, when the second split molds 62 and 62 are brought into close contact with each other, the concave molds are combined to form the molding space S. The molding space S is formed so as to correspond to the remaining chemical liquid discharge cylinder portion 3 and the remaining gripping piece 4 that are not molded by the second split molds 62 and 62. The remaining part of the chemical liquid discharge cylinder part 3 formed in the molding space S is a part of the cylinder part body 31 on the tip side of the cutting auxiliary part 33 and the closing part 34. The part of the gripping piece 4 molded in the molding space S is the remaining part of the side gripping parts 41, 41 and the tip gripping part 42.

  Furthermore, the upper surface formed at right angles to the mating surfaces of the pair of first split dies 61, 61 and the lower surface formed at right angles to the mating surfaces of the pair of second split dies 62, 62 are configured to be in surface contact. Yes. The pair of second split dies 62, 62 are configured to come in contact with and separate from the upper surfaces of the pair of first split dies 61, 61 in a state where the respective mating surfaces are in surface contact.

  Therefore, the first boundary p <b> 1 between the first split molds 61, 61 and the second split molds 62, 62 is provided on the distal end side (upper side) from the cutting assisting portion 33 of the chemical liquid discharge cylinder portion 3, and the gripping piece 4. Are provided across the side gripping portions 41, 41. That is, the first boundary p <b> 1 is provided between the lower end of the side surface gripping portions 41, 41 of the gripping piece 4 and the upper end of the chemical solution discharge tube portion 3. Further, one and the other of the pair of first split dies 61, 61 and the boundary p2 between the pair of second split dies 62, 62 are cut at the center of the cylinder core so that the ampoule 1 becomes a point target, and at least the gripping piece 4 Are provided across the side gripping portions 41, 41.

  Next, a method for manufacturing the ampoule 1 according to this embodiment will be described with reference to FIGS. 1 and 3 to 5. First, as shown to Fig.3 (a), a thermoplastic resin is inject | emitted in a cylinder shape and shape | molded in the state which heated the resin molding (parison) 7 (parison injection process). Next, as shown in FIG. 3B, the pair of first split dies 61 and 61 are closed to grip and hold a part of the outer periphery of the parison 7 in a heated state (parison). Holding step). At this time, the second split molds 62, 62 remain open.

  Thereafter, as shown in FIG. 4A, the parison 7 corresponding to the distal end side (upper side) and a part of the gripping piece 4 (part of the side surface gripping part 41) from the cutting assisting part 33a of the chemical liquid discharge cylinder part 3. (A parison 7 on the base end side (downward side) with respect to the first boundary position P1) is sandwiched between the pair of first split dies 61 and 61 from both sides in the radial direction, and the inside of the parison 7 is set to a positive pressure ( Pressure forming) or a negative pressure in the gap between the first split molds 61, 61 and the parison 7 (vacuum forming), and the chemical solution storage part 2 and a part of the chemical liquid discharge cylinder part 3 including the cutting assisting part 33a are integrated. Molding (first molding step). In the first molding step, the chemical solution discharge cylinder portion 3 is not formed on the tip side (upper end side) from the first boundary position P1, and the tip end of the chemical solution discharge tube portion 3 remains the cylindrical parison 7. , Open to the outside. The distal end of the chemical liquid discharge cylinder portion 3 is closed by forming the closing portion 34 in the second molding step performed thereafter.

  Next, as shown in FIG. 4 (b), the chemical solution storage nozzle 8 is inserted from the parison 7 which is not molded in the first molding step into a cylindrical shape in the first molding step. And the base end part is fixed to the nozzle fixing | fixed part 32, and the chemical | medical solution 5 is accommodated in the chemical | medical solution storage part 2 from the chemical | medical solution discharge cylinder part 3 (chemical | medical solution accommodation process).

  Next, as shown in FIG. 5 (a), a pair of second split dies 62, 62 are arranged in the radial direction on the remaining parison 7 portion (the parison 7 on the tip side (upper side) from the first boundary position P1). The remaining chemical solution discharge cylinder part 3 is formed by sandwiching from both sides and setting the inside of the parison 7 to a positive pressure or the gap between the second split molds 62 and 62 and the parison 7 to a negative pressure (second forming step).

  In addition, the chemical solution discharge cylinder portion 3 formed by the process of the second forming step is formed with a bump-like resin reservoir 35 in which a part of the parison 7 melted at the time of forming is hung down along the inside of the cylindrical main body 31. May be. This resin reservoir 35 tends to be formed on the distal end side (upper side) from the first boundary position P1 of the chemical liquid discharge cylinder portion 3.

  Further, as shown in FIG. 1B, the molded gripping piece 4 is less likely to be subjected to the force applied to the first split molds 61, 61 and the second split molds 62, 62, and the first boundary position P1 and the second An opening 43 may be formed at a position where the boundary position P2 intersects.

  The second molding step is also a sealing step for sealing (sealing) the chemical solution 5 stored in the chemical solution storage unit 2 by closing the distal end side of the chemical solution discharge tube unit 3. Then, as shown in FIG.5 (b), the ampule 1 shape | molded by opening the 1st split molds 61 and 61 and the 2nd split molds 62 and 62 is released (split mold open process).

  Thus, the 1st boundary position P1 used as the boundary of the part of the chemical | medical solution discharge cylinder part 3 shape | molded with the 1st split molds 61 and 61 and the part of the chemical | medical solution discharge | emission cylinder part 3 shape | molded with the 2nd split molds 62 and 62 is as follows. The tip side (upper side) from the cutting assisting portion 33. That is, the cutting assisting portion 33 of the ampoule 1 is located on the base end side (lower side) with respect to the first boundary position P1, and is molded by the first split dies 61, 61 in the first molding step. Since the resin reservoir 35 is formed on the distal end side (upper end side) of the first boundary position P1 in the second molding step, the ampoule 1 manufactured by this method uses the cutting auxiliary portion 33 as the resin reservoir 35. It is provided on the base end side.

  Therefore, even if the resin reservoir 35 is formed in the chemical liquid discharge cylinder portion 3 in the manufacturing process, when the chemical liquid discharge cylinder portion 3 is cut and opened by the cutting assisting portion 33, the resin reservoir 35 is Since the chemical reservoir 35 and the remaining chemical discharge cylinder 3 are removed together with a part of the chemical discharge cylinder 3 in which the resin reservoir 35 is formed, the opened chemical discharge cylinder 3 is inserted into the nozzle. The hindered resin reservoir 35 does not remain. Therefore, even when the resin reservoir 35 is formed in the chemical solution discharge cylinder portion 3, it can be handled as a conforming product that does not hinder the quality in the usage state, and the yield can be increased.

  In addition, the gripping piece 4 that is gripped when the chemical discharge cylinder part 3 is cut and opened by the cutting auxiliary part 33 can be formed simultaneously with the formation of the chemical liquid discharge cylinder part 3. A part of the parison 7 is formed by being sandwiched from both sides in the radial direction at the boundary between the pair of first split dies 61 and 61 and the boundary between the pair of second split dies 62 and 62. The gripping piece 4 thus molded is a part corresponding to the boundary between the pair of first split molds 61 and 61 and the second boundary corresponding to the boundary between the pair of second split molds 62 and 62. It is provided so as to include the position P2. Further, the gripping piece 4 is a portion corresponding to a portion where the surface formed perpendicular to the boundary between the first split dies 61 and 61 and the surface formed perpendicular to the boundary between the second split dies 62 and 62 are in surface contact. It is provided so as to include a certain first boundary position P1. At the position where the first boundary position P1 and the second boundary position P2 of the gripping piece 4 cross each other, it is difficult for force to be applied to the first split molds 61, 61 and the second split molds 62, 62, resulting in poor molding. is there. Therefore, the openings 43 and 43 are easily formed at this position.

  However, even if a part of the gripping piece 4 formed away from the chemical solution discharge cylinder portion 3 in the manufacturing process is locally opened, the chemical solution 5 is sealed in the chemical solution discharge tube portion 3. Therefore, the opening 43 of the gripping piece 4 is not communicated with the chemical solution discharge cylinder portion 3. Therefore, the chemical solution 5 stored in the chemical solution storage unit 2 does not leak outside through the opening 43 of the gripping piece 4. In addition, the chemical solution storage unit 2 and the chemical solution discharge tube unit 3 are not provided with such an opening by arranging the gripping piece 4 at a position where such an opening 43 can be easily formed. Therefore, even when a part of the gripping piece 4 is locally opened, it can be handled as a conforming product that does not hinder the quality in the usage state, and the yield can be increased.

  Further, in the conventional manufacturing method of the ampule 1a, the first split molds 61 and 61 are used to mold the cylindrical body 31 and the nozzle fixing portion 32 on the base end side (lower side) with respect to the cutting assisting portion 33a, and the second The split molds 62, 62 formed the distal end (upper side) cylindrical main body 31 including the cutting assisting portion 33 a, the cutting assisting portion 33 a, and the closing portion 34. That is, the first boundary position P1a is provided on the base end side with respect to the cutting assisting portion 33a. Therefore, when the chemical solution storage nozzle is inserted into the chemical solution storage portion 2a from the chemical solution discharge cylinder portion 3a in the chemical solution storage step, the passage of the chemical solution storage nozzle is blocked until the base end portion reaches the nozzle fixing portion 32a. There was no site.

  According to the manufacturing method of the ampule 1 according to the present embodiment, the first boundary position P1 is provided on the distal end side (upper side) from the cutting assisting portion 33. Therefore, when the chemical solution storage nozzle is inserted from the chemical solution discharge tube portion 3 into the chemical solution storage portion 2 in the chemical solution storage step, the cutting assisting portion until the base end of the chemical solution storage nozzle reaches the nozzle fixing portion 32a. 33 protrudes and the inner peripheral diameter is narrowed. Therefore, although it may be an obstacle to the passage of the chemical solution storage nozzle, the cutting assisting portion 33 according to the present embodiment does not protrude inward from the nozzle fixing portion 32 (formed outside the nozzle fixing portion 32 by α). Is configured so as not to hinder the passage. Further, since it does not hinder the passage of the inserted chemical solution storage nozzle, it comes into contact with the cutting assisting portion 33 that is still heated and easily deformed, and the ridge portion formed inside faces downward. Therefore, it is possible to prevent the cutting assisting portion 33 from being poorly molded and obstructed from being opened. Therefore, even if it changes from the conventional 1st boundary position P1a to a position like this embodiment, it is comprised so that the chemical | medical solution 5 can be accommodated similarly to the past, without leaving a problem in opening.

  In addition, the manufacturing method of the plastic ampule for chemical | medical solution which concerns on this invention, and the plastic ampule for chemical | medical solution are not limited to above-mentioned embodiment, In the range which does not deviate from the summary of this invention, it can add various change. Of course.

  Although the manufacturing method of the plastic ampule 1 for chemical | medical solutions which concerns on the said embodiment demonstrated the example which manufactures one cylindrical plastic ampule 1 for chemical | medical solutions, it is not limited to this. For example, the manufacturing method of the present invention can also be applied to the case where a split mold capable of forming a plurality of chemical ampules 1, 1,. That is, the first boundary position P1 is set on the distal end side of each cutting aid 33a of each plastic ampule 1, 1,... For each chemical solution, and the side surface gripping portions 41, 41,. ... Can be manufactured by using the split mold provided with the second boundary position P2 so as to straddle...

  Although the manufacturing method of the plastic ampule 1 for chemical | medical solution which concerns on the said embodiment demonstrated the example in which the holding piece 4 was shape | molded from the both ends of the chemical | medical solution discharge cylinder part 3 to the front end side, it is not limited to this. . For example, even if the plastic ampule 1 for chemical liquid is not provided with the gripping piece 4, it can be prevented from interfering with the nozzle by the resin reservoir 35 when opened. Even when the gripping piece 4 is provided, the chemical liquid plastic ampule 1 may include only the side surface gripping portions 41 and 41. Since the opening 43 is formed in the side surface holding parts 41, 41, the opening 43 is not formed in the chemical solution discharge cylinder 3, and the chemical solution 5 sealed inside does not leak to the outside.

  DESCRIPTION OF SYMBOLS 1, 1a ... Plastic ampule for chemical | medical solutions, 2, 2a ... Chemical solution accommodating part, 21 ... Accommodating part main body, 22 ... Bottom part, 3, 3a ... Chemical liquid discharge | emission cylinder part, 31 ... Cylinder part main body, 32 ... Nozzle fixing | fixed part, 33, 33a ... cutting assisting part, 34 ... blocking part, 35, 35a ... resin reservoir, 4, 4a ... gripping piece, 41 ... side gripping part, 42 ... tip gripping part, 43 ... opening, 5 ... medicinal solution, 6 ... split mold, 61 ... 1st split mold (1st split mold), 62 ... 2nd split mold (2nd split mold), 7 ... Parison, 8 ... Nozzle for chemical solution storage, P1, P1a ... 1st boundary position, P2, P2a ... Second boundary position, p1 ... first boundary, p2 ... second boundary, S ... forming space

Claims (2)

A chemical solution storage portion for storing a chemical solution, and a chemical solution discharge cylinder portion that communicates with the chemical solution storage portion and extends from the chemical solution storage portion and closes the tip, and covers the entire circumference in the circumferential direction so as to be cut when opened. a drug solution discharge tube having a cutting assistance part formed, a manufacturing method of a chemical liquid plastic ampule to obtain Bei a gripping piece which projects from the front end side portion than the auxiliary cutting part of the drug solution discharge tube,
A part of a resin molded product molded into a cylindrical shape with a thermoplastic resin and sandwiched between a pair of first split molds from both sides in the radial direction, and a part of a chemical liquid discharge cylinder part including a chemical liquid storage part and a cutting auxiliary part A first molding step for integrally molding a part of the gripping piece, a chemical solution containing step for containing the chemical solution inside the chemical solution containing portion formed by the pair of first split molds, and a pair for the remaining resin molded product portions second sandwiching from both sides in the radial direction by a split mold, and a second forming step of forming the remainder of the drug solution discharge tube and the rest of the gripping piece,
The pair of first split molds and the pair of second split molds are formed in a state where the mating surfaces where the pair of first split molds overlap each other and the mating surfaces where the pair of second split molds overlap each other are on the same plane. When the pair of first split molds and the pair of second split molds are overlapped, the resin molded product molded in contact with each of the pair of first split molds and each of the pair of second split molds method for producing a chemical liquid plastic ampule characterized that you have been configured such that the gripping piece is located at a portion. A chemical solution storage portion for storing a chemical solution, and a chemical solution discharge cylinder portion that communicates with the chemical solution storage portion and extends from the chemical solution storage portion and closes the tip, and covers the entire circumference in the circumferential direction so as to be cut when opened. a drug solution discharge tube having a cutting assistance part formed, a chemical liquid plastic ampule to obtain Bei a gripping piece projecting from the portion of the distal end side of the auxiliary cutting part of the drug solution discharge tube,
The pair of first split molds and the pair of second split molds overlap with each other such that the pair of first split molds overlap with each other and the pair of second split molds overlap with each other. A pair of first pieces configured so that the gripping piece is positioned at a portion of the resin molded product formed in contact with each of the pair of first split molds and each of the pair of second split molds. Using a split mold and a pair of second split molds, a part of a resin molded product that is molded into a cylindrical shape with a thermoplastic resin and is heated is sandwiched from both sides in the radial direction by a pair of first split molds, A first liquid forming part that integrally forms a part of the chemical liquid discharge cylinder part including the cutting auxiliary part and a part of the gripping piece, and a chemical liquid that contains the chemical liquid inside the chemical liquid container formed by the pair of first split molds A radial direction with a pair of second split molds in the housing step and the remaining resin molding part Sandwiching from the side, the chemical liquid plastic ampule characterized by Rukoto produced by a second forming step of forming the remainder of the drug solution discharge tube and the rest of the gripping piece.

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