JP2002126040A - Cap and manufacturing method for the same, and drug container using the same - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a cap, which can be pierced through even with a piercing tool whose end is not sharp and eliminate liquid leakage from a tap body when pierced through with the piercing tool or after the piercing tool it pulled out, and a manufacturing method for the cap, and a drug container using the cap. SOLUTION: The cap 10 is provided with an outer frame body 11, which is provided with an approximately cylindrical hollow part 12, and an approximately cylindrical elastic body 14 for sealing the hollow part 12. Pressure is applied to the elastic body 14 in a direction orthogonal to the axial direction of the cap 10 (the elastic body 14) by a wedge 21 pressed into a gap (a press-in section 18) between the inner peripheral surface 12a of the hollow part 12 and the outer peripheral surface 14c of the elastic body 14. The pressure allows a pore 15a to undergo compressive deformation for the purpose of forming a slit extended in the axial direction of the elastic body 14 and blocked by a thin part 16 at the side end of the top surface 14a of the elastic body 14.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cap attached to a mouth of a medicine container such as an infusion bag or an infusion bottle, or a mouth of a side injection tube or the like in an infusion line.

[0002]

2. Description of the Related Art In general, the mouth of a medicine container such as an infusion bag or an infusion bottle containing an infusion or an injection, or a side injection tube or the like in an infusion line used for infusion or the like. The part (co-injection part) is sealed with a cap provided with a stopper made of an elastic body such as rubber or thermoplastic elastomer. For this reason, when injecting another medicine into a medicine container or an infusion line, a sharp piercing tool such as a metal injection needle that can pierce the stopper has been used.

However, a sharp needle may cause an accidental stab of a finger, and it is strongly required to prevent such an accident from the viewpoint of countermeasures against infectious diseases. Therefore,
In recent years, in order to enable insertion of non-sharp piercing tools,
A cap provided with a slit (cut) in a plug body has been proposed. However, since the slit is usually formed by piercing a blade into an elastic body constituting a plug body, chips of the elastic body are likely to remain in the slit, and when the cap is used, the chips are used as a chemical. This may cause a problem of mixing in the container.

[0004] Further, since a medicine container to which this type of cap is attached is generally a container for storing a drip solution, an injection solution, etc., for example, when sterilization or the like is performed, moisture may enter the container or foreign matter may enter the container. Strictly need to be prevented. Therefore, a measure has been taken to provide a thin film at one end of the slit so that the slit does not penetrate the entire plug (JP-A-5-124664). Since the elastic body is slightly deformed, it is extremely difficult to form a thin film with high accuracy.

On the other hand, as a method for inserting a piercing tool having a sharp tip, a plug body provided with a small hole instead of a slit has been proposed (registered utility model No. 301343).
No.). The pores, unlike slits, can be formed at the same time as the plug is molded in the mold,
There is no problem of the above-mentioned chip and the problem of controlling the dimensional accuracy of the thin film. However, since the plug with the pore has a smaller pressure applied to the piercing device than the one with the slit, when the piercing device is inserted, the plug is inserted between the pore and the piercing device. There is a possibility that a liquid leak may occur or a liquid leak may occur after the piercing device is removed.

For this reason, when providing a pore in the plug,
So that appropriate pressure is applied to the piercing device from around
It is required that a pressure is applied to the plug in advance, but it is difficult to dispose the plug in the outer frame of the cap while applying pressure during the production of the cap. Therefore, an object of the present invention is to allow a penetrating instrument to be inserted even when the tip is not sharp, and furthermore, liquid does not leak from the plug at the time of inserting the piercing instrument or after removing the piercing instrument. An object of the present invention is to provide a cap, a method for producing the cap, and a medicine container using the cap.

[0007]

Means for Solving the Problems and Effects of the Invention As a result of intensive studies to solve the above problems, the present inventors have found that a substantially cylindrical hollow portion provided in an outer frame body has a substantially cylindrical shape. In a cap sealed with a plug made of an elastic body, the elastic body includes (1) pores extending in the axial direction of the cap (elastic body), and one end of the elastic body as necessary. (2) such pores are formed into slits by wedges press-fitted into the gap between the inner peripheral surface of the cavity and the outer peripheral surface of the elastic body. When the piercing tool is used, even if the tip of the piercing tool is not sharp, the piercing tool can be easily inserted into the elastic body. Pressure is sufficient and a cap that does not leak is obtained. Found a new fact, it has led to the completion of the present invention.

That is, a cap according to the present invention is a cap including an outer frame having a substantially cylindrical hollow portion, and a substantially columnar elastic body for sealing the hollow portion. The body is pressurized in a direction perpendicular to the axial direction of the cap by a wedge pressed into a gap between the inner peripheral surface of the hollow portion and the outer peripheral surface of the elastic body, and includes a slit extending in the axial direction. It is characterized by having.

According to the cap of the present invention, since the elastic body serving as the plug is subjected to pressure in a direction perpendicular to the axial direction of the elastic body, even when the piercing tool is inserted, the piercing tool is inserted. Appropriate pressure can be applied to the passing tool, and as a result, it is possible to prevent liquid leakage from occurring between the elastic body and the piercing tool. Further, even after the piercing tool is removed, it is possible to prevent the liquid from leaking from the slit. Furthermore, since the elastic body is formed with a slit in advance, it is possible to easily insert a piercing tool whose tip is not sharp. When the slit is closed by a thin portion at one end of the elastic body, it can be subjected to a sterilization process or the like as it is while maintaining the advantage that a piercing tool having a sharp end can be easily inserted. Can be something.

[0010] In the cap according to the present invention, the slit is preferably formed by compressing and deforming a pre-formed pore in the elastic body by press-fitting a wedge. The shape of the pores in a direction (cross section of the elastic body) orthogonal to the axial direction of the elastic body includes a substantially elliptical shape, a spindle-shaped vertical cross-sectional shape, a substantially rectangular shape, a substantially circular shape, and the like. By making the original shape of the slit formed by press fitting of the wedge into a pore, the pore can be formed at the same time as the elastic body is molded in the mold. Therefore, there is no need to pierce the elastic body with a blade for the purpose of forming the slit, and there is a problem that chips of the elastic body remain in the slit and that control of dimensional accuracy of the thin film becomes difficult. Absent.

[0011] In the cap of the present invention, when forming the thin portion, the preferable position is not particularly limited. However, it is easy to wipe the top surface of the cap, and foreign matter inside the slit during storage of the cap can be prevented. It is preferable that the elastic member is provided at an end on the top surface side of the elastic body from the viewpoint of reliably preventing the mixture. In the cap of the present invention, it is preferable that the wedges are press-fitted at positions facing each other with the slit as a center. In this case (specifically, when two wedges are press-fitted), it is easy to adjust the pressure applied to the elastic body to be uniform. In particular, when the shape of the pores before being crushed by the wedge press-fitting is substantially elliptical, spindle-shaped vertical cross-sectional, or substantially rectangular in the cross section in a direction orthogonal to the axial direction of the elastic body, the fine narrow It is preferable to provide a wedge press-fit portion at a position that is line-symmetric with respect to the long side direction or long diameter direction of the hole. This makes it possible not only to make the pressure applied to the elastic body uniform, but also to form a slit with high adhesion without causing excessive distortion when the pores are crushed.

[0012] Further, it is more preferable that the wedge is connected to an annular pedestal that can be fitted into the hollow portion of the outer frame. In this case, it is sufficient to apply pressure to the pedestal when press-fitting the wedge, and as a result, it is easier to make the pressure applied to the elastic body uniform than in the case where pressure is applied to each wedge.
Further, by connecting the wedge to the pedestal, the operation of press-fitting the wedge can be performed more easily. In the cap of the present invention, the outer frame is made of a thermoplastic, and the elastic body is made of a thermoplastic elastomer having compatibility with the thermoplastic. It is preferable that the elastic body and the elastic body are integrated by fusion. In this case, the manufacturing process of the cap, particularly the process of fitting the elastic body into the hollow portion and bonding the outer frame body and the elastic body can be simplified.

As described above, the cap of the present invention is
(I) Since the elastic body is pre-pressed, the risk of liquid leakage when the piercing device is inserted or after the piercing device is removed is sufficiently reduced. ) Since the elastic body has the slit, it can be inserted even if the tip is not a sharp needle. Further, when one end of the slit is closed by a thin portion, the slit can be subjected to a sterilization process or the like as it is.

Therefore, the cap of the present invention is suitable as a cap to be attached to a mouth portion of a medicine container such as an infusion bag or an infusion bottle or a mouth portion (mixed injection portion) of a side injection tube or the like of an infusion line. The cap according to the present invention is configured such that a substantially cylindrical elastic body has pores extending in the axial direction of the elastic body and closed at one end by a thin portion, and then the outer peripheral surface of the elastic body is formed. After forming an outer frame body surrounding and surrounding the elastic body, a wedge is pressed into a gap between the inner peripheral surface of the hollow portion and the outer peripheral surface of the elastic body to compress and deform the pores in a slit shape. can do.

By performing the above manufacturing steps, it is possible to form a cap having an outer frame having a substantially cylindrical hollow portion and a substantially columnar elastic body for sealing the hollow portion. Moreover, the elastic body can be in a state where pressure is applied in a direction orthogonal to the axial direction. Also, pores formed in advance in the elastic body can be crushed to form slits. In the method for manufacturing a cap of the present invention, after the elastic body is formed of a thermoplastic elastomer, a thermoplastic plastic having compatibility with the thermoplastic elastomer is injected around the elastic body to form the outer body. Forming the frame is preferable from the viewpoint of simplifying the manufacturing process of the cap, particularly, the process of fitting the elastic body into the hollow portion of the outer frame body and bonding the elastic body to the outer frame body.

A drug container of the present invention is provided with the above-mentioned cap of the present invention. By attaching the cap of the present invention to the mouth of the medicine container in a conventional manner, (i) medicine and medicine can be injected and mixed without using a sharp needle, and (ii) piercing It is extremely unlikely that liquid will leak when the tool is inserted or removed, and (iii) the drug container is sufficiently sealed and can be used as is for sterilization. Can be provided. Such a drug container can be suitably used in a medical site or the like as enhancing safety during use.

[0017]

DESCRIPTION OF THE PREFERRED EMBODIMENTS [Cap] Next, a cap according to the present invention will be described in detail with reference to the drawings. (First Embodiment) FIG. 1 is a side sectional view showing an embodiment (first embodiment) of a cap according to the present invention, and FIG. 2 is a schematic view showing an assembling process of a cap 10 shown in FIG. FIG.

FIG. 3 shows a state in which the cap 10 shown in FIG.
FIGS. 3A and 3B are diagrams showing a state in which is removed, wherein FIG. 3A is a plan view and FIG. Also, FIG.
3A is a cross-sectional view taken along the line AA of FIG. 3A, and FIG.
FIG. 3 is a sectional view taken along the line BB in FIG. In the first embodiment,
As shown in FIG. 2, a wedge 21 is press-fitted from a bottom side 14b of the elastic body into a groove-shaped press-fitting portion (gap) 18 provided between the outer peripheral surface 14c of the elastic body 14 and the inner peripheral surface 12a of the cavity. By doing so, the pores 15a provided in advance in the elastic body 14 are crushed, and the slits 1 shown in FIG.
It is 5.

As shown in FIG. 1, for example, as shown in FIG. 1, a cap 10 as a completed product obtained by press-fitting a wedge 21 has an outer frame body 11 having a substantially cylindrical hollow portion (reference numeral 12 in FIG. 2). A substantially columnar elastic body 14 for sealing the cavity 12 is provided. In addition, the flange portion 11a of the outer frame body
Is used when the cap 10 is connected to the mouth of the medicine container or the like, as described later. A pressure is applied to the elastic body 14 in a direction perpendicular to the axial direction of the elastic body 14 by the press fit of the wedge 21. Therefore, even when the piercing device is inserted into the slit 15, appropriate pressure is applied to the piercing device, and liquid leakage from between the elastic body 14 and the piercing device is prevented. Also, liquid leakage after removing the piercing implement is prevented.

As described above, the slit 15 is obtained by compressing and deforming the fine hole 15a provided in the elastic body 14 in advance by press-fitting the wedge 21. In the first embodiment, the slit 15 (the pore 15 a shown in FIG. 2 before the compression deformation) is closed by a thin portion 16 provided on the top surface side 14 a of the elastic body 14. As described above, since the slit 15 is not penetrated by the thin portion 16, the sealing performance of the cap 10 can be maintained at a higher level until the piercing tool is inserted into the slit 15.

On the other hand, although the slit 15 is not penetrated as described above, it is closed by the thin portion 16 that can be easily pierced. , Can be inserted into the slit 15. In the first embodiment,
A concave portion 17 is provided at a position where the slit 15 and the thin portion 16 are formed on the top surface 14a of the elastic body. As a result, the opening end of the slit is
The puncture position can be easily recognized even if it does not appear in (a) (see FIG. 3 (a)).

In the first embodiment, the groove-shaped press-fit portions (gap) 18 for press-fitting the wedges 21 face each other around the fine holes 15a (or the slits 15 after compression deformation). Position. More specifically, the press-fit portion (gap) 18 is formed at a position that is line-symmetric with respect to the major axis direction of the fine hole 15a having a spindle-shaped vertical cross-section in the cross section of the elastic body 14 (FIG. 3).
(b)). Thus, the pressure applied to the elastic body 14 by press-fitting the wedge 21 can be made uniform, and excessive pressure is not generated by compressively deforming the fine holes 15a.
Further, the adhesion of the slit 15 can be improved.

FIG. 5 (a) is a plan view showing the wedge member 20 in FIG. 1, and FIG. 5 (b) is a one-side sectional view of FIG. 5 (a), and FIG.
It is CC sectional drawing of (a). In the first embodiment, wedges 21 are press-fitted into two groove-shaped press-fit portions (gap) 18 provided at two locations. Here, the two wedges 21 are attached to the ring-shaped pedestals 22, respectively, and form wedge members 20 shown in FIG. In the first embodiment, the wedge member 20 is inserted into the hollow portion 12 of the outer frame body 11, whereby the wedge 21 is pressed into the press-fit portion (gap) 18 of the wedge 21 (see FIG. 2).

As shown in FIG. 5, the wedge member 20 is
Are provided with ridges 23 on the outer peripheral surface thereof. The protruding ridge fits with the groove 13 provided on the inner peripheral surface 12 a of the hollow portion of the outer frame body 11. The wedge member 20 is fixed to the portion 12. As a result, the pressure applied to the elastic body 14 in a direction orthogonal to the axial direction can be stabilized. (Second Embodiment) FIG. 6 is a side sectional view showing another embodiment (a second embodiment) of the cap according to the present invention.
FIG. 7 is a schematic view showing an assembly process of the cap 30 shown in FIG.

FIG. 8 shows a state in which the wedge member 40 is removed from the cap 30 in FIG.
FIGS. 3A and 3B are diagrams showing a state in which is removed, wherein FIG. 3A is a plan view and FIG. FIG. 9 (a) shows FIG.
FIG. 8A is a cross-sectional view taken along the line D-D in FIG.
FIG. 7 is a sectional view taken along the line EE of FIG. In the second embodiment,
As shown in FIG. 7, a wedge 41 is inserted from a top surface 34a of the elastic body into a groove-shaped press-fit portion (gap) 38 provided between the outer peripheral surface 34c of the elastic body 34 and the inner peripheral surface 12a of the cavity. By press-fitting, the pores 35a provided in advance in the elastic body 34 are crushed, and the slits 3 shown in FIG.
It is 6.

A cap 30 as a finished product obtained by press-fitting a wedge 41 seals the outer frame body 31 having a substantially cylindrical hollow portion 32 and the hollow portion 32 as shown in FIG. And a substantially columnar elastic body 34. The flange portion 31a of the outer frame body is
0 is connected to the mouth of the medicine container or the like. The elastic body 34 is inserted into the elastic body 34 by press fitting of the wedge 41.
Pressure is applied in a direction perpendicular to the axial direction of No. 4. Therefore, even when the piercing device is inserted into the slit 35, sufficient pressure is applied to the piercing device, and liquid leakage from between the elastic body 34 and the piercing device is prevented.

As described above, the slit 35 is obtained by compressing and deforming the fine hole 35a provided in the elastic body 34 in advance by press-fitting the wedge 41. In the second embodiment, the slit 35 (the pore 35a shown in FIG. 7 before the compression deformation) is closed by a thin portion 36 provided on the top surface 34a of the elastic body 34. Since the slit 35 is not penetrated by the thin portion 36 in this manner, the sealing property of the cap 30 can be maintained until the piercing tool is inserted into the slit 35.

On the other hand, although the slit 35 is not penetrated as described above, the slit is closed by the thin portion 36 which can be easily pierced. , Can be inserted into the slit 35. In the second embodiment,
A concave portion 37 is provided at a position where the slit 35 and the thin portion 36 are formed on the top surface 34a of the elastic body. As a result, the opening end of the slit is
The puncture position can be easily recognized even when the puncture position does not appear in (a) (see FIG. 8 (a)).

In the second embodiment, the groove-shaped press-fit portions (gap) 38 for press-fitting the wedges 41 face each other around the circular pores 35 a in the cross section of the elastic body 34. (FIG. 8B)
reference). Thereby, the elastic body 34 is pressed by the press fit of the wedge 41.
The pressure applied to the slit 35 can be made uniform, and no excessive pressure is generated by compressing and deforming the pores 35a, and the adhesion of the slit 35 can be improved.

FIG. 10 (a) is a bottom view showing the wedge member 40 in FIG. 6, and FIG. 10 (b) is a one-side sectional view of FIG. 6 (a), and FIG.
It is FF sectional drawing of (a). In the second embodiment, wedges 41 are press-fitted into two groove-shaped press-fit portions (gap) 38 provided at two locations. Here, each of the two wedges 41 is attached to a ring-shaped pedestal 42, and forms a wedge member 40 shown in FIG. In the second embodiment, the wedge member 40 is inserted into the hollow portion 32 of the outer frame body 31 so that the wedge 41 can be pressed into the press-fit portion (gap) 38 of the wedge 41 (see FIG. 7).

The wedge member 40 is, as shown in FIG.
2 is provided with a ridge 43 on the outer peripheral surface. The protruding ridge fits with the groove 33 provided on the inner peripheral surface 32 a of the hollow portion of the outer frame body 31. The wedge member 40 is fixed to the cavity 32. As a result, the pressure applied to the elastic body 34 in the direction orthogonal to the axial direction can be stabilized. In the first and second embodiments, the thin portions 16 and 36 are both used.
Are provided on the top surfaces 14a, 34a of the elastic bodies 14, 34. However, the position of the thin portion is not limited to this, and a thin portion may be provided on the bottom surfaces 14b and 34b (not shown). In addition, as long as a sufficient sealing property of the cap is ensured, the thin portion need not be provided.

(Elastic Body) As the elastic body in the cap of the present invention, various materials used as conventional stoppers for drug containers can be used. An elastic member such as a plastic elastomer is used. In particular, when a thermoplastic elastomer is used, the processability of the elastic body can be improved, and the cap can be integrally formed with the outer frame.
In the case where the elastic body and the outer frame are integrally formed, it is preferable to use, as the thermoplastic elastomer forming the elastic body, one having compatibility with the thermoplastic resin constituting the outer frame. Thereby, the adhesiveness between the elastic body and the outer frame body can be improved.

Examples of the thermoplastic elastomer usable in the present invention include styrene-ethylene / butylene-styrene block copolymer (SEBS), styrene-butadiene-styrene block copolymer (SBS), and styrene-isoprene-styrene block. Copolymer (SIS),
Modified SEBS such as maleic acid modification, styrene-ethylene / propylene-styrene block copolymer (SEP
S), styrene-based elastomers such as styrene-ethylene / butylene block copolymer (SEB) and styrene-ethylene / propylene block copolymer (SEP); olefin-based elastomers such as ethylene-propylene block copolymer; polyurethane-based elastomers And the like.

The characteristics of the elastic body in the cap according to the present invention are not particularly limited. Generally, the elastic body is not so strong or hard that it is difficult to penetrate a medical infusion needle, and it is stored during normal storage. Any material having a strength that does not easily deform or break it may be used. The elastic body used for the cap of the present invention is JIS
A hardness [spring hardness Hs (JIS A) measured by the method described in JIS K 6301] is 20 to 70.
Is preferable, and it is more preferable that it is 30-50. Also, the compression set of the elastic body is determined by JI so that it is not damaged even if the medical infusion needle is repeatedly withdrawn and inserted.
The value measured by the method described in SK6301 [compression set CS (%), heat treatment temperature / time: 70 ° C. × 22
Is preferably 30 or less.

(Outer Frame) In the case where the cap according to the present invention is applied to a plastic medicine container or a plastic side injection part of an infusion line, the outer frame is provided with various types of medical devices. Plastic can be used. Such plastics include, for example, polyolefins such as polyethylene, polypropylene and poly-4-methylpentene; polycyclic olefins such as ethylene-tetracyclododecene copolymer; acrylonitrile-butadiene-styrene copolymer (ABS); polyethylene naphthalate ( Polyesters such as PEN), polyethylene terephthalate (PET) and polyarylate; and benzene polymers such as polyphenylene sulfide (PPS).

As poly-4-methylpentene, "TPX" (trade name) of Mitsui Chemicals, Inc., and as ethylene-tetracyclododecene copolymer, "Apel" (trade name) of Mitsui Chemicals, Inc. , Respectively. When the above plastic is used for the outer frame,
The mouth can be sealed by welding the flange of the outer frame body to the flange of the mouth of the medicine container or the like.

In the case where a thermoplastic elastomer is used as the elastic body, the outer frame body and the elastic body can be integrally formed by using the above-mentioned plastic having thermoplasticity as the outer frame body. it can. Furthermore, by using a material compatible with the elastic body as the plastic of the outer frame body, it is possible to improve the adhesion between the elastic body and the outer frame body as described above. When the cap according to the present invention is applied to a glass medicine container, a metal plate such as aluminum can be used for the outer frame. In this case, the elastic body can be fixed by winding the outer frame made of the metal plate around the flange at the mouth of the medicine container.

An elastic film can be arranged at the portion of the inner surface of the outer frame that contacts the glass, if necessary. Thereby, the sealing performance of the cap can be further improved. (Wedge press-fitting portion) At least one wedge press-fitting portion is provided between the outer peripheral surface of the elastic body and the inner peripheral surface of the hollow portion.
When two press-fitting portions are provided, it is preferable to provide the press-fitting portions at positions facing each other with a hole (slit) formed in advance in the elastic body as a center. When the shape of the pore in the cross section of the elastic body is an elliptical shape or a spindle-shaped vertical cross-sectional shape, or a rectangular shape, the press-fit portion is positioned at a position that is line-symmetric with respect to the long side direction or long diameter direction of the pore. More preferably, it is provided. When three or more locations are provided, the center of the pores (slits)
It is preferable to provide press-fit portions at positions that are point-symmetric with each other. Thereby, the pressure applied to the elastic body by the press-fitting of the wedge can be made uniform, and no excessive pressure is generated by compressively deforming the pores, and the adhesiveness of the slit can be further improved.

The press-fitting portion of the wedge is preferably provided along a joint between the outer peripheral surface of the elastic body and the inner peripheral surface of the hollow portion.
In addition, the size of one press-fit portion is determined by the compression characteristics of the elastic body,
The size is set according to the size of pores provided in the elastic body in advance, and is not particularly limited. However, usually, the angle from the center of the elastic body (center angle) Is preferably 20 to 120 °.
It is set to be 90 °. The shape of the wedge is not limited to this, and the wedge may be formed in an annular shape in order to apply pressure from the entire outer periphery of the elastic body.

The depth of the press-fitting portion is set according to the thickness of the elastic body, the compression characteristics and the like, and is not particularly limited, but is usually 2 to 20 mm, preferably 3 to 1 mm.
It is set within a range of 5 mm. The width of the press-fit portion (the length in the radial direction of the elastic body) is set according to the size of the elastic body, the compression characteristics, the size of the pores provided in advance in the elastic body, the size of the wedge to be press-fitted, and the like. Although not particularly limited, the maximum width is usually 0.2
４4 mm, preferably in the range of 0.5〜2.5 mm.

(Slits / pores) The cross-sectional shape of the pores formed in advance in the elastic body is not particularly limited, and as described above, a substantially elliptical, spindle-shaped vertical cross-sectional shape, a substantially rectangular shape, a substantially rectangular shape, or the like. A circular shape or the like can be mentioned, and among these, a shape that is easily deformed into a slit shape by press fitting of a wedge is preferable, and specifically, an elliptical or spindle-shaped vertical cross-sectional shape (so-called eye shape) is preferable.

When two wedge press-fitting positions (gap) are provided at positions facing each other, the orientation of the pores should be determined so that the major axis in the elliptical or spindle-shaped longitudinal cross-section is on the axis of symmetry. preferable. Although the size of the pore is not particularly limited, the major axis is usually set to about 0.5 to 10 mm, preferably 1 to 7 mm, and more preferably about 2 to 4 mm. On the other hand, the minor axis is set according to the press-fit position (gap) of the wedge and the size of the wedge, and is not particularly limited, but is usually 0.2 to 2 mm, preferably 0.3 to 1 m.
m.

(Wedge) The same plastic as that of the outer frame is used for the wedge that is press-fitted between the outer peripheral surface of the elastic body and the inner peripheral surface of the hollow portion. The size of the wedge, especially the thickness of the wedge, is set in accordance with the size of the elastic body, the compression characteristics, the size of the pores provided in advance in the elastic body, the size of the press-fit portion (gap), and the like. Although not particularly limited, the magnitude of the pressure applied in the direction orthogonal to the axial direction of the elastic body by press-fitting of the wedge causes the pores to move at least on the top surface side of the elastic body (thin portion). Side), it is necessary to set such that it can be deformed into a slit shape.

Specifically, the maximum thickness of the wedge is 0.5 to 5 m
m, preferably about 1 to 3 mm. The length and width of the wedge portion are preferably set to be substantially the same as the length and width of the gap. The wedges are, for example, as shown in FIGS.
It is preferably connected to annular pedestals 22 and 42 which can be inscribed in the inside. Wedges 21, 41 are attached to annular bases 22, 42.
Are connected to the outer peripheral surfaces 14c and 34c of the elastic body and the inner peripheral surfaces 12a and 3
2a, the wedge members 20, 4
The direction in which 0 is press-fitted (that is, the position where the press-fitting portion is provided) may be on the bottom side of the cap as in the first embodiment (see FIGS. 2, 3 (b) and 4). ) Or on the top side (see FIGS. 7, 8 (b) and 9).

[Manufacturing Method of Cap] The cap of the present invention can be manufactured, for example, as follows.
First, pores (15a, 35a) extending in the axial direction are formed in a substantially columnar elastic body (14, 34). On this occasion,
If necessary, one end (1) of the elastic body (14, 34)
6, 36) to leave a thin portion (16, 36) (FIG. 1).
Or FIG. 6, FIG. 4 or FIG. 9).

Next, the outer peripheral surface (14c, 34) of the elastic body
An outer frame (11, 31) is formed in contact with and surrounding c). Then, for example, as shown in FIG. 2 or FIG.
A gap (press-fit portion 18, 3) between the inner peripheral surface (12a, 32a) of the cavity and the outer peripheral surface (14c, 34c) of the elastic body.
8), wedges (21, 41) are pressed into the fine holes (15).
The cap (10, 30) of the present invention is obtained by compressively deforming a, 35a) into a slit shape.

When the elastic body is formed of a thermoplastic elastomer and the outer frame is formed of a thermoplastic plastic having compatibility with the thermoplastic elastomer, the outer frame is formed around the elastic body. Caps can be manufactured by injecting thermoplastics. That is, the cap can be integrally molded, and the manufacturing process of the cap, particularly, the process of fitting the elastic body into the hollow portion of the outer frame body and the process of bonding the outer frame body and the elastic body can be simplified. .

The pores provided in the elastic body may be formed at the same time as the elastic body is formed in the mold. [Drug Container] FIG. 11 is a front view showing an example of a drug container 90 provided with the cap 10 of the present invention. The medicine container 90 includes a flange portion 91a of a mouth member 91 attached to the mouth portion thereof and an outer frame 1 of the cap 10 of the present invention.
The first flange portion 11a is welded.

The cap according to the present invention, the method for producing the same, and the medicine container using the same are not limited to the above examples, and the design can be changed as appropriate without changing the gist of the present invention.

[Brief description of the drawings]

FIG. 1 is a side sectional view showing one embodiment of a cap according to the present invention.

FIG. 2 is a schematic view showing an assembly process of the cap 10.

3A is a plan view showing a state in which the wedge member 20 has been removed from the cap 10, and FIG. 3B is a bottom view thereof.

4A is a sectional view taken along the line AA of FIG. 3A, and FIG. 4B is a sectional view taken along the line BB of FIG.

5A is a plan view showing the wedge member 20, FIG. 5B is a one-side sectional view of FIG. 5A, and FIG. 5C is a sectional view of FIG.

FIG. 6 is a side sectional view showing another embodiment of the cap according to the present invention.

FIG. 7 is a schematic diagram showing an assembly process of the cap 30.

8A is a plan view showing a state in which the wedge member 40 has been removed from the cap 30, and FIG. 8B is a bottom view thereof.

9A is a sectional view taken along the line DD in FIG. 8A, and FIG. 9B is a sectional view taken along the line EE in FIG. 8A.

10A is a bottom view showing the wedge member 40, FIG. 10B is a one-side sectional view of FIG. 10A, and FIG. 10C is a sectional view of FIG.

FIG. 11 is a front view showing an example of a medicine container provided with the cap of the present invention.

[Explanation of symbols]

DESCRIPTION OF SYMBOLS 10 Cap 11 outer frame body, 12 hollow part, 12a inner peripheral surface,
DESCRIPTION OF SYMBOLS 13 Groove, 14 elastic body (plug), 14c outer peripheral surface, 15 slit, 15a pore, 16 thin portion, 17 concave portion, 18 press-fit portion (gap) 20 wedge material, 21 wedge, 22 pedestal 30 cap 31 outside Frame, 32 cavities, 32a inner peripheral surface,
33 groove, 34 elastic body (plug), 34c outer peripheral surface, 35 slit, 35a pore, 36 thin part, 37 concave part, 38 press-fitting part (gap) 40 wedge material, 41 wedge, 42 pedestal 90 infusion bag ( Drug container)

Claims (9)

[Claims] 1. A cap comprising: an outer frame body having a substantially cylindrical hollow portion; and a substantially columnar elastic body for sealing the hollow portion, wherein the elastic body is formed of the hollow portion. Pressure is applied in a direction perpendicular to the axial direction of the cap by a wedge press-fitted into a gap between the inner peripheral surface and the outer peripheral surface of the elastic body, and a slit extending in the axial direction is provided. cap. 2. The cap according to claim 1, wherein said slit is formed by compressing and deforming a fine hole formed in said elastic body in advance by press-fitting a wedge. 3. The cap according to claim 1, wherein the wedges are press-fitted at positions facing each other around the slit. 4. The cap according to claim 1, wherein the wedge is connected to an annular pedestal that can be fitted into a cavity of the outer frame. 5. The outer frame body is made of a thermoplastic, the elastic body is made of a thermoplastic elastomer having compatibility with the thermoplastic plastic, and the outer frame body and the elastic body are fused. The cap according to claim 1, wherein the cap is integrated. 6. The cap according to claim 1, wherein said slit is closed by a thin portion at one end of said elastic body. 7. A substantially cylindrical elastic body is formed with pores extending in the axial direction of the elastic body and closed at one end by a thin portion, and then in contact with the outer peripheral surface of the elastic body. After forming an outer frame body surrounding the cap, a wedge is pressed into a gap between an inner peripheral surface of the hollow portion and an outer peripheral surface of the elastic body to compressively deform the pores into a slit shape. Manufacturing method. 8. The outer frame body is formed by forming the elastic body with a thermoplastic elastomer and then injecting a thermoplastic plastic having compatibility with the thermoplastic elastomer around the elastic body. Item 8. The method for producing a cap according to Item 7. 9. A drug container provided with the cap according to claim 1.