JP5602862B2 - 心拍出量の低下、心臓停止、循環停止、又は卒中発作を起こした個体を処置するための装置 - Google Patents
心拍出量の低下、心臓停止、循環停止、又は卒中発作を起こした個体を処置するための装置 Download PDFInfo
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Description
BR 血液還流手段
BL 血液流路
BA 分析ユニット
R 貯蔵ユニット
D 配量ユニット
A1 誘導管
A2 バイパス管
CIRD 管理され、統合制御された蘇生装置の基本モジュール
F 搬送手段
O オキシジェネレータ
G ガスブレンダ
LF 白血球フィルタ
A/K 評価ユニット/管理ユニット
WT 熱交換器
M モニタユニット
S1、S2… 物質
Si1… 制御信号
V1、V2… 配量手段、弁
MB 混合容器
SE1、SE2… センサ
SEE1、SEE2… センサ結果
BAE 血液分析結果
A 分析ユニット
SEH センサユニット
KE 作用ユニット
MS 体液に少なくとも一種の物質を放出するための手段
MM 体液に機械的影響を及ぼすための手段
MT 体液に熱的影響を及ぼすための手段
Claims (18)
- 個体から血液の少なくとも一部を取り出すための、個体(P)に適用可能な血液取出手段(BE)と、血液分析結果(BAE)の形で、血液の少なくとも一つの特性を捕捉して提供するための、間接的又は直接的に血液取出手段と連結された分析ユニット(BA)と、個体(P)に適用可能な還流手段(BR)と間接的又は直接的に連結されており、還流手段(BR)を介して個体に物質を放出するために形成された作用ユニット(KE)とを備えた、心臓停止又は循環停止又は卒中発作を起こした個体を処置するための装置において、
作用ユニット(KE)が少なくとも一つの貯蔵ユニット(R)を含んでおり、前記貯蔵ユニットが少なくとも二種の物質(S1、S2、…)を備蓄すること、
貯蔵ユニット(R)と組み合わされた配量ユニット(D)が設けられており、前記配量ユニットが、少なくとも分析ユニット(BA)によって確定された血液分析結果(BAE)を考慮して、少なくとも二種の物質(S1、S2、…)から少なくとも一種の物質を選択するか、又は物質(S1、S2、…)の少なくとも二種から成る混合物を調製すること、
前記少なくとも一種の選択された物質又は前記混合物が、間接的又は直接的に、還流手段(BR)を介して個体内に送り込まれ得ること、並びに
評価ユニット及び管理ユニット(A/K)が設けられており、前記評価ユニット及び管理ユニットが、少なくとも分析ユニット(BA)並びに配量ユニット(D)と有線又は無線で情報交換しており、少なくとも血液分析結果(BAE)に基づいて、配量ユニット(D)を制御するための制御信号(Si 1 、Si 2 、…)を発信することを特徴とする装置。 - 個体(P)に適用可能な血液取出手段(BE)が、血液流路(BL)を介して、個体(P)に適用可能な還流手段(BR)と連結されていること、
血液流路(BL)に沿って、分析ユニット(BA)並びに貯蔵ユニット(R)及び配量ユニット(D)が設けられていること、及び
少なくとも一種の選択された物質又は混合物が、改変血液を得るため、個体から取り出した血液と、還流手段(BR)を介して個体に放出される前に混合可能であることを特徴とする請求項1に記載の装置。 - 血液流路(BL)に沿って、少なくとも一つの搬送手段(F)が流量を調整するために設けられていることを特徴とする請求項2に記載の装置。
- 分析ユニット(BA)が多数のセンサ(SE1、…SEn)を含んでおり、前記センサの各々が、少なくとも一つの血液パラメータを捕捉することを特徴とする請求項1ないし3のいずれか一項に記載の装置。
- 分析ユニット(BA)が、以下の血液パラメータ、即ちpH値、酸素分圧(pO2)、二酸化炭素分圧(pCO2)、カリウム含有量(K)、ナトリウム含有量(Na)、カルシウム含有量(Ca)、塩基過剰(BE)、乳酸値(La)、グルコース含有量(Gu)の少なくとも一つをセンサにより捕捉することを特徴とする請求項4に記載の装置。
- 貯蔵ユニット(R)が多種の物質(S1、S2、…)を備蓄しており、前記物質が、固体、液体、又は気体の形で存在し、且つ隔てられた貯蔵チャンバ内に備蓄されており、前記物質が、別々に、又は組み合わされて、配量ユニット(D)により配量されて添加され得ることを特徴とする請求項1ないし5のいずれか一項に記載の装置。
- 配量ユニット(D)が、少なくとも一つの混合容器(MB)を備えており、前記混合容器が、個々に制御可能な配量手段(V1、V2、…)を介し、個々の貯蔵チャンバと連結されていること、及び
前記少なくとも一つの混合容器(MB)が、更なる制御可能な配量手段を介し、間接的又は直接的に還流手段(BR)と連結されていることを特徴とする請求項6に記載の装置。 - 少なくとも一種の備蓄された物質(S1、S2、…)が、以下の物質又は物質クラス、即ちアルカリ性又は酸性の緩衝液、ナトリウム含有量、カリウム含有量、及び/又はカルシウム含有量に影響を及ぼす物質、血液希釈物質、フリーラジカルスカベンジャー、グルタミン酸塩、アスパラギン酸塩、心臓リズムを安定化する物質(リドカイン)、白血球数、浸透活性物質、つまり塩、グルコース、タンパク質から選択されていることを特徴とする請求項1ないし7のいずれか一項に記載の装置。
- モニタユニット(M)が設けられており、前記モニタユニットが、個体の少なくとも一つのパラメータを捕捉するための少なくとも一つの測定手段を備えており、前記パラメータが、平均動脈圧、中心静脈圧、肺動脈圧、酸素飽和度、及び血液温度を含む個体の生理的パラメータの群から選択されており、その際、モニタユニット(M)が、評価ユニット及び管理ユニット(A/K)と、それぞれ少なくとも一つの一方的な情報交換のために接続されていることを特徴とする請求項1ないし8のいずれか一項に記載の装置。
- 分析ユニット(BA)が、個体(P)の血液の少なくとも一つの特性を捕捉するセンサユニット(SEH)を含むことを特徴とする請求項1ないし9のいずれか一項に記載の装置。
- センサユニット(SEH)が、間接的又は直接的に血液取出手段(BE)と連結していることを特徴とする請求項10に記載の装置。
- センサユニット(SEH)が、以下の血液のパラメータ、即ちpH値、酸素分圧、二酸化炭素分圧、カリウム含有量、ナトリウム含有量、カルシウム含有量、塩基過剰、乳酸値、グルコース含有量の少なくとも一つを捕捉することを特徴とする請求項10又は11に記載の装置。
- 分析ユニット(A)、作用ユニット(KE)、並びに評価ユニット及び管理ユニット(A/K)が、ポータブルで統一的な構造ユニットとして実施されていることを特徴とする請求項1ないし12のいずれか一項に記載の装置。
- センサユニット(SEH)が、前記統一的な構造ユニットの一部であることを特徴とする請求項10又は13に記載の装置。
- 血液流路(BL)に沿って、血液取出手段(BE)と還流手段(BR)の間に、還流手段(BR)の直前に配置されたバイパス管(A2)が設けられており、前記バイパス管により、個体内に還流させるべき改変血液の一部を分析ユニット(BA)内に送ることができ、少なくとも一つの捕捉可能な血液パラメータに関して目標値と実際値を比較し、相違がある場合には、配量ユニット(D)が、少なくとも一種の物質の血液流路(BL)内への添加量を変更することを特徴とする請求項2ないし14のいずれか一項に記載の装置。
- 還流手段(BR)と間接的又は直接的に連結している熱交換ユニット(WT)が設けられていることを特徴とする請求項1ないし15のいずれか一項に記載の装置。
- 評価ユニット及び管理ユニット(A/K)が、制御信号(Si1、Si2、…)を発信し、且つ搬送手段(F)及び熱交換ユニット(WT)に送り、したがって個体内に供給される少なくとも一種の物質の圧力、流速、及び温度を選択できることを特徴とする請求項16に記載の装置。
- 血液流路(BL)に沿って、血液取出手段(BE)と還流手段(BR)の間に、血液に対する酸素補給及び低減化ユニットが設けられていることを特徴とする請求項2ないし17のいずれか一項に記載の装置。
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