JP5543850B2 - Powdered drug inhalation device - Google Patents

Description

  The present invention relates to a device for allowing a user to inhale a powdered medicine from a mouth at a predetermined inhalation rate.

  Administration of drugs to the lung is very effective for administration of various drugs for local and systemic treatment. Conventionally, a device for sending a powdered drug into the lung airway by inhalation from the mouth is known.

  And in order to make a chemical | medical agent act effectively using such a device, in addition to the particle diameter of a formulation, a dispersibility, etc., control of the inhalation rate of a chemical | medical agent is important. Generally, the respiration rate of a human is 28.3 L / min. For example, in the inhaler of Patent Document 1, the inhalation rate is adjusted to 20 to 60 L / min, or 40 to 80 L / min. In addition, many currently known devices are designed based on the human respiratory rate. However, patient skill is necessary for proper suction, and in many cases, suction is not performed well. In particular, when the inhalation speed is too fast, the drug collides with the user's mouth or pharynx and does not reach the deep lung. In this case, not only the expected effect does not appear, but a drug remaining in the oral cavity or throat often leads to side effects such as oral infection or voice loss.

  Under such circumstances, a device having a control means for controlling the suction speed to a desired range has been proposed.

  In patent document 2, the powder inhaler which has the flow regulator provided with the piston and the spring is proposed. In this powder inhaler, when the piston covers the intake port and the user uses it, the piston head is pulled backward at a constant speed by a spring fixed to the inner wall of the suction partial chamber, so that the air flow is It is said that the speed can be controlled. It has also been proposed to taper the piston rod.

  However, Patent Document 2 does not show a range in which the inhalation speed can be actually controlled. Further, after all, the adjustment of the inhalation speed is generated by the patient from the device. You must judge by listening to the sound.

Special table 2004-508903 gazette JP 2008-62080 A

  The present invention has been made in view of the circumstances as described above, and it is an object of the present invention to provide a device that reliably prevents inhalation when a user sucks at a speed exceeding a predetermined suction speed. .

  In order to solve the above problems, the present invention provides a device having the following characteristics.

A first invention is a device for inhaling a powdered medicine from a mouth within a predetermined inhalation speed range, and a flow in which air outside the device flows into the device as a result of inhalation from the inhalation port. An inlet, a medicine container having a pedestal on which a powdery medicine-containing capsule can be mounted, a first flow path communicating the inlet and the medicine container, and a second flow communicating the medicine container and the inlet road, and respiratory actuated control means, a body Ru provided with, and a slide cover with a guide piece, the control unit only when the suction speed is within a predetermined range, said first flow path and The second flow path is opened at the same time. If the suction speed does not reach a predetermined speed, the first flow path is closed. If the suction speed exceeds a predetermined speed range, the second flow path is closed. control can der to close the second flow path is, the body, slide mosquito With a drawable from over, the guide piece protrudes to the inside of the sliding cover, with the drawer body, the pedestal of the medicine container portion is guided to a predetermined direction by the guide piece, exposed fixed.

  In the second aspect of the invention, the first flow path and the second flow path are folded back at the medicine storage portion on which the pedestal is disposed and provided approximately in parallel, and the control means is an elastic fixed inside the device. A body and a substantially T-shaped closing piece that is connected to the elastic body and can close the first flow path and the second flow path.

  According to a third aspect of the present invention, the closing piece has a rotation shaft portion, a leg portion extending from the rotation shaft portion, and a valve provided at the tip of the leg portion, and the valve is connected to the medicine storage portion. The first valve capable of closing the outlet of the first flow path toward the first valve and the second valve capable of closing the inlet from the medicine container to the second flow path are integrally formed, and the inhalation speed is When the predetermined range is exceeded, the closing piece turns to the second flow path side by turning with the turning shaft portion as a base point, whereby the first valve is turned to the device inner wall on the first flow path side. The second valve is closed when the second valve approaches and contacts the device inner wall on the second flow path side.

  According to a fourth aspect of the present invention, the device includes a rotatable impeller in the medicine container, and a pedestal is provided on the impeller.

In the fifth invention, the slide cover includes an operation needle, and the operation needle can penetrate the outer wall of the powdery medicine-containing capsule attached to the pedestal to form a through hole.

According to the first invention, when the user sucks at a speed that does not reach the predetermined suction speed range or at a speed exceeding the predetermined suction speed range, the suction is surely impossible. Further, the device can be designed to be small, the medicine can be easily stored in the storage portion, and the usability of the device is improved.

  According to the second invention, the device can be designed to be small, and the above-described effect is efficiently exhibited.

  According to the third aspect of the invention, the device can be designed to be small, and the suction speed can be controlled more reliably.

  According to the fourth invention, in addition to the above-described effects, the medicine can be efficiently released only in a speed range in which suction is possible.

According to the fifth aspect , the through-hole can be reliably provided in the capsule mounted on the pedestal, and the drug can be reliably released from the through-hole during suction.

(A) (B) is the perspective view which illustrated one Embodiment of the device of this invention. It is the schematic which illustrated one Embodiment of the internal structure of the device of this invention. It is the perspective view which illustrated one embodiment of the base and the impeller. It is the schematic which illustrated one Embodiment of the inhalation control method by the control means of the device of this invention. It is a disassembled perspective view which illustrates one Embodiment of the device of this invention. It is an internal perspective view which illustrated the form which has a slide mechanism as one embodiment of the device of the present invention. FIG. 7 is an internal perspective view corresponding to FIG. 6. It is the perspective view which illustrated the inside of the corner part of a slide cover. 1 is an internal schematic diagram illustrating one embodiment of a device of the present invention. FIG. 10 is an internal perspective view corresponding to the embodiment illustrated in FIG. 9. It is a figure which shows the suction speed and time at the time of suck | inhaling without using a device. It is a figure which shows the suction speed and time at the time of suctioning using the device of this invention.

  The device of the present invention will be described with reference to the drawings.

  1A and 1B are perspective views illustrating an embodiment of a device of the present invention. The device 1 of the present invention is a device for allowing a user to inhale a powdered drug orally.

  The device 1 is designed in a long box shape, and a mouthpiece 21 can be attached to the tip. The shape of the device 1 can be designed as appropriate. For example, it is considered that the device 1 is designed to be easily held by the user. The size of the device 1 can also be designed as appropriate, but is preferably smaller than that of a human hand.

  FIG. 2 is a schematic view illustrating an embodiment of the internal structure of the device of the present invention. The device 1 includes an inlet 2, an inlet 3 for supplying air from the back side to the inside of the device 1, a pedestal 4 on which a drug capsule is mounted, and a first flow path 5 that communicates the inlet 3 with the pedestal 4. , A second flow path 6 that communicates the base 4 and the suction port 2, and a breath actuated control means 7.

  The first flow path 5 leads from the inlet 3 to the medicine storage section 8, and the medicine storage section 8 leads to the second flow path 6. The second flow path 6 communicates with the suction port 2. The first flow path 5 and the second flow path 6 have a hairpin shape that is folded back by the medicine storage portion 8 and are arranged substantially parallel to each other. Further, a partition wall 9 is provided between the first flow path 5 and the second flow path 6, thereby separating the first flow path 5 and the second flow path 6.

  The suction port 2 is provided at the end of the device 1 in the longitudinal direction. A mouthpiece (not shown in FIG. 2) can be appropriately attached to the suction port 2, and the user can inhale the medicine from the suction port 2 directly or through the mouthpiece. The size, shape, and the like of the suction port 2 are not particularly limited, and when the mouthpiece is attached, it can be designed according to the shape, size, etc. of the mouthpiece.

  When the user starts suction from the suction port 2, air outside the device 1 flows into the device 1 through the inlet 3. It is desirable that the device 1 of the present invention does not communicate with the outside other than the inlet 2 and the inlet 3. The air flowing in from the inflow port 3 immediately flows to the first flow path. The shape and the like of the inlet 3 can be designed as appropriate.

  FIG. 3 is a perspective view illustrating an embodiment of a pedestal including an impeller.

  The medicine container 8 is provided with a rotatable impeller 10. The impeller 10 has a plurality of blades 10a and rotates by receiving air flowing in from the inlet 3. The number and shape of the blades 10a of the impeller 10 can be appropriately designed in consideration of the set suction speed, the amount of medicine, the amount of air flowing in from the inflow port 3, the air resistance, and the like.

  On this impeller 10, the base 4 for mounting | wearing with a powdery medicine containing capsule is provided. The shape of the pedestal 4 can correspond to the shape of the capsule. For example, the side surface of the base 4 can be formed into a substantially elliptical cross section formed integrally by the curved surface 4a and the parallel surface 4b. The size of the base 4 is designed to be smaller than the diameter of the impeller 10.

  The pedestal 4 rotates in conjunction with the rotation of the impeller 10 and diffuses and releases the powdered medicine inside the attached capsule as fine powder out of the pedestal 4 by centrifugal force. In this case, the powdery drug-containing capsule is provided with a through-hole for releasing the drug. Further, one or more notch-shaped openings 4c can be provided around the pedestal 4 to efficiently release the medicine. The shape and size of the opening 4c can be designed as appropriate, and for example, can be designed in a circular shape. The arrangement position of the opening 4c can also be designed as appropriate, but it is preferably provided on the curved surface 4a of the pedestal 4 in view of the efficiency of drug release. The medicine container 8 is formed as a space in which the impeller 10 and the pedestal 4 can rotate.

  By designing the device 1 as described above, the air flowing in from the inflow port 3 by suction from the suction port 2 passes through the first flow path 5 as shown by the arrow in FIG. The medicine on the pedestal 4 provided in the medicine container 8 is released, and air accompanied with this medicine is discharged from the suction port 2 through the second flow path 6 and sucked by the user. The

  The device 1 can control the inhalation speed of the user by the breath actuated control means 7. When the suction speed is equal to or lower than a predetermined speed, the first flow path 5 is closed by the control means 7. The control means 7 opens the first channel 5 and the second channel 6 at the same time only when the suction speed is within an appropriate range, and when the suction speed exceeds a predetermined speed, the control means 7 It is possible to control the flow path 6 to be closed.

  Here, the “closing” of the flow path includes not only a state where the flow path is completely closed, but also a state where the flow path is closed to the extent that the user feels that suction is difficult. Further, the inhalation speed of the device 1 can be set as appropriate. Preferably, it can determine in the range of 20-50 L / min.

  FIG. 4 is a schematic view illustrating one embodiment of the inhalation control method by the control means of the device of the present invention.

  The control means 7 includes an elastic body 71 fixed inside the device 1, and a substantially T-shaped closing piece 72 that is connected to the elastic body 71 and can close the first flow path 5 and the second flow path 6. And is formed by. The closing piece 72 is adjacent to the partition wall 9. Moreover, as the elastic body 71, various springs etc. can be used suitably.

  More specifically, the closing piece 72 includes a rotation shaft portion 721, a leg portion 722 extending from the rotation shaft portion 721, and a valve protruding in the device inner wall W1 and W2 directions at the tip of the leg portion 722. 723, which are integrated as one closing piece 72. An end portion of the elastic body 71 is fixed to a side surface of the leg portion 722.

  The valve 723 includes a first valve 723a that can close the outlet of the first flow path 5 toward the medicine storage section 8, and a second valve that can close the entrance from the medicine storage section 8 to the second flow path 6. The valve 723b is integrally formed. A bent portion 724 is provided at the tips of the first valve 723a and the second valve 723b.

  Then, when not inhaling, as illustrated in FIG. 4A, the control means 7 makes the bent portion 724 at the tip of the first valve 723a abut against the device inner wall W1 by the force of the elastic body 71, The first flow path 5 is in a closed state. The bent portion 724 can be surely closed. Further, a part of the side surface of the leg portion 722 of the closing piece 72 is in contact with the partition wall 9. On the other hand, the second valve 723b is separated from the device inner wall W2.

  When the user starts to inhale from the inlet 2 and air flows into the first flow path 5 from the inlet 3, the first valve 723 a receives air resistance and suppresses the force of the elastic body 71, and the rotating shaft portion. It rotates to the 2nd flow path 6 side from 721 as a base point. That is, as the second valve 723b approaches the device inner wall W2, the first valve 723a is separated from the device inner wall W1.

  Strictly speaking, the negative pressure applied to the suction port 2 by the user to start the suction is applied to the suction port 2 side of the first valve 723a, so that the valve 723a is opened. During the air flow, the position of the first valve 723 is determined in a state where the pressure difference applied to the front and back surfaces of the first valve 723a and the opposite force due to the repulsive force of the elastic body 71 are balanced. Of course, since the pressure of the air flowing through the flow path is also applied to the second valve 723b, more strictly, the second valve 723b is designed in consideration of the equilibrium state of the elastic body-valve system including the whole.

  Therefore, when inhaling at an appropriate speed, as shown in FIG. 4B, the first valve 723a is separated from the device inner wall W1, and at the same time, the second valve 723b is also separated from the device inner wall W2. It becomes a state. As a result, the air that has passed through the first flow path 5 flows out from the gap in which the first valve 723a is separated into the medicine storage unit 8, rotates the impeller 10 in the medicine storage unit 8, and the medicine on the base 4 To release. Then, the air accompanied with the medicine flows from the gap between the second valve 723b and the device inner wall W2 to the second flow path 6, and is discharged from the suction port 1 and sucked by the user.

  When the inhalation is stopped or when the inhalation speed becomes lower than the appropriate speed, the state returns to the state shown in FIG.

  When the suction speed becomes equal to or higher than the appropriate speed, the amount of air flowing in from the inflow port 3 is increased as compared with the proper speed. Therefore, the first valve 723a receives an even stronger air resistance, and the second valve 723b also receives the air resistance of the air flowing from the medicine container 8, and the closing piece 72 suppresses the force of the elastic body 71 and 2 further turns to the flow path 6 side. Therefore, as illustrated in FIG. 4C, the bent portion 724 at the tip of the second valve 723 b approaches and contacts the device inner wall W <b> 2, and the second flow path 6 serves as an entrance from the drug storage unit 8. Closed in the vicinity. Again, the second flow path 6 is reliably closed by the bent portion 724. Therefore, the suction from the suction port 2 becomes impossible, and the inflow of air from the inlet 3 is also stopped.

  In other words, when the user applies excessive suction pressure (negative pressure), the pressure difference between the front and back surfaces of the two valves 723a and 723b further increases, and the elastic body-valve system The equilibrium position moves to the side that narrows the second flow path 6. Thereby, when the suction pressure is increased to some extent, the flow rate gradually decreases, and finally, when the closing piece 72 completely closes the second flow path 6, the flow rate becomes zero. In addition, when the suction pressure is increased to a certain extent by such an operation of the elastic body-valve system, the flow rate is suddenly lowered, so that the suction resistance that the user receives, that is, the sense of resistance, increases rapidly. Even when inhalation is started, if the suction pressure is increased, the resistance received by the user is suddenly reduced when the first flow path 5 is greatly opened and the flow rate is higher than a certain level. . Since such feedback is provided directly to the user's respirator and the relationship “the range in which the flow rate is in the proper range≈the range in which the user feels less resistance” is established, It becomes very easy to maintain the suction pressure in a state where 6 is sufficiently open, that is, in a range where the flow rate is appropriate.

  Then, when the suction speed is reduced and the proper range is reached, the closing piece 72 is returned to the first flow path 5 side again by the action of the elastic body 71. That is, as shown in FIG. 4B, the first valve 723a is separated from the device inner wall W1, and at the same time, the second valve 723b is also separated from the device inner wall W2. Therefore, the medicine can be sucked again at an appropriate inhalation speed.

  As described above, the device 1 of the present invention can be inhaled only at an appropriate inhalation speed, and when it exceeds a predetermined inhalation speed, the inhalation is surely impossible. Therefore, it is possible to prevent the sucked medicine from colliding with the user's oral cavity and pharynx, and the medicine can be surely reached to the deep lung.

  In the device 1 of the present invention, as described above, the inhalation state and the inhalation impossible state can be continuously changed according to the suction speed of the user. For this reason, the user will endeavor to adjust his / her inhalation speed so that the inhalation speed becomes an appropriate speed, that is, at the time of aspiration, so that the device is in the state of FIG. . Therefore, the device 1 of the present invention also exhibits a learning effect that the user naturally wears an appropriate respiration rate.

  The elastic body 71 takes into consideration the set suction speed, the size of the first valve 723a and the second valve 723b, the air resistance, and the like, and the first flow path 5 and the second flow as described above. The material, shape, etc. are designed so that the control by opening and closing the path 6 is realized. Further, by adjusting the elastic constant, it is possible to arbitrarily set the suction speed at which the medicine can be inhaled.

  FIG. 5 is an exploded perspective view illustrating one embodiment of the device of the present invention.

  The device 1 of the present invention provided with the suction speed control mechanism as described above may take various forms, but preferably the suction port 2, the pedestal 4, the control means 7 and the like are provided as having a slide mechanism. The main body 11 and the slide cover 12 may be included. In FIG. 5, a guide piece 15 and an operation needle 16 are provided on the slide cover 12.

  In this embodiment, for example, an uneven groove or the like is provided on the outer side surface of the main body 11 and the inner side surface of the slide cover 12 corresponding thereto, and the main body 11 is pulled out along this groove, whereby the base portion 4 Can be exposed to the outside of the device. The exposed pedestal 4 can be easily loaded with a medicine capsule. At this time, the slide mechanism may be any of various other mechanisms, and in particular, has a structure that can ensure the hermeticity inside the device 1 so that the control means 7 functions reliably.

  FIG. 6 is an internal perspective view illustrating a form having a slide mechanism as one embodiment of the device of the present invention. FIG. 7 is an internal perspective view corresponding to FIG. FIG. 8 is a perspective view illustrating the inside of the corner portion of the slide cover. In FIGS. 6 and 7, the reference numerals and descriptions of the points described with reference to FIGS. 2 and 4 are omitted.

  The inside of the main body 11 is exposed from the slide cover 12 by pulling the drawer end 13 on the side opposite to the suction port 2 backward.

  The slide cover 12 is provided with a guide piece 15 protruding inward at a corner portion 14 (shown in FIG. 8) on the drawer end 13 side. The guide piece 15 has an inclined surface 15 a that descends from the side surface 12 a side of the slide cover 12 to the drawing end 13 side, and a fixed surface 15 b that is substantially parallel to the side surface 12 a of the slide cover 12. Further, as illustrated in FIG. 7, the guide pieces 15 (15 a, 15 b) are formed on the same plane as the base 4 with a predetermined length in the vertical direction from the upper surface of the slide cover 12. Therefore, it is designed so as not to hinder the rotation of the impeller 10.

  When the device 1 of the present invention is provided with a slide mechanism and the pedestal 4 is pulled out, the pedestal 4 is rotated by the impeller 10, and therefore it is considered that the stability of the drug capsule is lacking. 15, the stability of the base 4 can be ensured.

  Specifically, as illustrated in FIGS. 6 and 7, (A) when the main body 11 is pulled out from the slide cover 12, the curved surface 4 a of the long cylindrical base 4 having the curved surface 4 a and the parallel surface 4 b is It abuts on the inclined surface 15 a of the guide piece 15. In this state, the pedestal 4 faces an arbitrary direction with respect to the drawer end portion 13. (B) When the main body 11 is further pulled out, the major axis direction of the base 4 is guided in a direction substantially parallel to the side surface 12 a of the slide cover 12 along the inclined surface 15 a of the guide piece 15. (C) When the drawing of the main body 11 is completed, the parallel surface 4b of the pedestal 4 and the fixed surface 15b of the guide piece 15 come into contact with each other, and the major axis direction of the pedestal 4 is substantially parallel to the side surface 12a of the slide cover 12. Fixed in any direction. Since the orientation of the pedestal 4 is fixed by the fixed surface 15b, the impeller 10 is in a non-rotatable state. Therefore, the pedestal 4 is stable, and the drug capsule can be easily attached to the pedestal 4.

  Note that the size, inclination angle, and the like of the guide piece 15 can correspond to the shape, size, fixing direction, and the like of the pedestal portion. For example, the inclination angle is preferably designed in the range of 5 to 45 °. This is because when the tilt angle is small, the device 1 becomes large, and when the tilt angle is too large, the pedestal 4 may not move smoothly along the tilted surface 15a.

  FIG. 9 is an internal schematic diagram illustrating one embodiment of the device of the present invention.

  The device 1 of the present invention can be provided with the operating needle 16 at an appropriate position inside the device 1. The operating needle 16 can freely operate insertion and extraction of the operating needle 16 from the capsule 17 held on the base 4 by pushing back the operating portion 16a.

  For example, as illustrated in FIGS. 6 and 7, when the device 1 of the present invention has a slide mechanism, the operating needle 16 can be operated as follows.

  First, as illustrated in FIG. 9A, the main body 11 of the device 1 is pulled out and the direction of the base 4 is adjusted. In FIG. 9A, as described above, the major axis direction of the pedestal 4 is adjusted in a direction substantially parallel to the side surface 12 a of the slide cover 12 by the fixing surface 15 b of the guide piece 15. The drug capsule 17 is mounted on this pedestal.

  Next, as illustrated in FIG. 9B, the main body 11 is pushed forward and inserted into the slide cover 12, and the pedestal 4 is disposed at a predetermined position. At this time, the pedestal 4 is maintained in the orientation adjusted as described above, and the opening 4 c provided in the curved surface 4 a of the pedestal 4 faces the operation needle 16.

  Then, as illustrated in FIG. 9C, the operating needle 16 is inserted into the drug capsule 17 from the opening 4c by pushing out the operating portion 16a, and the through-hole is opened through the outer wall of the capsule 17. As described above, the top portion 17a of the capsule 17 can be reliably captured by adjusting the orientation of the base 4. Therefore, the through hole can be opened at the same position of the capsule 17 with good reproducibility. Thereafter, as illustrated in FIG. 9D, the operating needle 16 is pulled out from the capsule 17. The encapsulated drug can be released from the through hole opened in the capsule 17.

  FIG. 10 is an internal perspective view corresponding to the form illustrated in FIG. As shown in FIG. 10, the pedestal 4 is arranged so that the opening 4c of the curved surface 4a faces the operation needle 16, and the operation needle 16 can be inserted and extracted from the opening 4c. In FIG. 10, the description of the medicine capsule is omitted.

  Note that one or two or more through holes of the drug capsule can be provided, and can be appropriately determined according to the amount of the drug to be released. Moreover, the outer wall of the capsule 17 can also be formed by penetrating two places at a time. Furthermore, the operation needle 16 can preferably be exemplified with a tip formed at an acute angle. Further, cone-shaped and multi-faced cut needles can also be used as appropriate.

  In addition, this invention is not limited to embodiment as above, Various forms are possible for details.

  In order to confirm the effect of the device of the present invention, an inhalation experiment by a human was conducted. As a comparative example, the inhalation speed was measured when a large inhalation was inhaled assuming a drug inhalation without using a device.

  As a result, as shown in FIG. 11, the suction speed reached 40-50 L / min, and the suction time did not continue for 2 seconds.

  On the other hand, in the Example using the device of this invention, when the suction speed became 35 L / min or more, it designed so that a 2nd flow path might be closed by a control means.

  As a result, as shown in Fig. 12, when the suction speed becomes too fast, the flow path is instantly blocked, and thereafter it can be confirmed that the suction can be performed slowly for 4-5 seconds at an appropriate suction speed of 20-30 L / min. It was.

DESCRIPTION OF SYMBOLS 1 Device 2 Inlet 3 Inlet 4 Base 4a Curved surface 4b Parallel surface 4c Opening 5 1st flow path 6 2nd flow path 7 Control means 71 Elastic body 72 Closing piece 721 Rotating shaft part 722 Leg part 723 Valve 723a 1st valve 723b 2nd valve 724 Bending part 8 Drug storage part 9 Bulkhead 10 Impeller 10a Wing 11 Main body 12 Slide cover 13 Drawer end part 14 Corner part 15 Guide piece 15a Inclined surface 15b Fixed surface 16 Operating needle 16a Operation Part 17 Drug capsule W1, W2 Device inner wall

Claims (5)

A device for inhaling a powdered medicine from a mouth in a predetermined inhalation speed range,
The inlet,
An inflow port through which air outside the device flows into the inside of the device along with inhalation from the inhalation port;
A medicine container having a pedestal on which a powdery medicine-containing capsule can be mounted;
A first flow path that communicates the inflow port with the medicine container;
A second flow path that communicates between the medicine container and the suction port, and a breath-actuated control means;
Has a body Ru provided with, and a slide cover with a guide piece,
The control means opens the first flow path and the second flow path at the same time only when the suction speed is within a predetermined range. When the suction speed does not reach the predetermined speed, the control means opens the first flow path. road is closed and also when the inhalation rate is out of the range of predetermined speed, Ri control can der to close the second flow path,
The main body can be pulled out from the slide cover, and the guide piece protrudes inside the slide cover. As the main body is pulled out, the base of the medicine container is guided and fixed in a predetermined direction by the guide piece. A device characterized by exposure .   The first flow path and the second flow path are folded back at the medicine storage portion and provided substantially in parallel. The control means is connected to the elastic body fixed inside the device, the elastic body, and the first flow path. The device according to claim 1, further comprising: a substantially T-shaped closing piece capable of closing one channel and the second channel. The closing piece has a rotating shaft portion, a leg portion extending from the rotating shaft portion, and a valve provided at the tip of the leg portion,
The valve
A first valve capable of closing the outlet of the first flow path toward the medicine container;
A second valve capable of closing the entrance from the medicine container to the second flow path is integrally formed;
When the suction speed exceeds a predetermined range, the closing piece rotates to the second flow path side by rotation with the rotation shaft portion as a base point, whereby the first valve is moved to the first flow path side. 3. The device according to claim 2, wherein the second flow path is closed by moving away from the device inner wall and the second valve approaching and contacting the device inner wall on the second flow path side.   The device according to any one of claims 1 to 3, wherein the device includes a rotatable impeller in the medicine container, and a pedestal is provided on the impeller. The slide cover includes an operation needle, and the operation needle can penetrate the outer wall of the powdery drug-containing capsule attached to the pedestal to form a through hole . device.

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