201231104 六、發明說明： 【發明所屬之技術領域】 本發明係關於一種吸入器。 .【先前技術】 本發明已特別設計用於具有一大致香煙形狀的主體的 模擬香煙裝置。然而，本發明係關於對於此一裝置的出 口閥的發展，其在吸入器的領域具有較廣的應用，舉 例而言，用於諸如氣喘吸入器的口服藥物遞送的醫療吸 入器。 在香煙替代品的領域，已有數種建立一模擬香煙的提 議。此一裝置具有肖越傳統尼古丁替代品錢（諸如貼 布及口香糖）的數種優點，其重新建立吸煙的實體動作 (此對一吸煙者而言係為心裡上重要的），且亦能夠以更 接近地複製上癮的吸煙者所欲的一香煙的藥物動力效 應’而以-劑量遞送尼古丁。因此，一吸煙者能夠獲得 類似來自一香煙的「癮頭」，而無須面對從一貼布或口香 糖緩慢的釋放’其無法產生此一瘾頭而導致無法預期的 服用及差的渴求成績及中斷比率。 一種模擬香煙具有可吸入混合物的一儲藏器及一出口 閥，該出口閥舉例而言，可藉由按壓一按鈕或咬住—香 煙的端而觸發。然而1於開啟閥的較佳機制係為提供 一呼吸啟動閥，因為此確保香煙將僅當使用者以一正常 201231104 香煙的方式吸吹在裝置上時才配給。 US 4,393,884揭露具有大的有彈力的「舌片」的此一 裝置，其具有一流動路徑通過其中。此舌片偏移至並非 與香煙的出口對齊的—第-位置，且可被吸吹至與香煙 的出口對齊的-第二位置’以提供從儲藏器至出口的一 流動路徑。此-裝置在第—位置難以密封。其亦將需要 相當的力量來吸吮舌片至開啟位置來抵抗一定位的彈簧 的動作及舌片構件相對大的質量，其將難以返回關閉位 置’意味著在吸吮力已經被移除之後配給仍將繼續。 US 6’889’678揭露具有一呼吸啟動閥的一模擬香煙的 另-範例》此專利揭露數個範例。此等範例之—者具有 -對磁鐵，其中-個磁鐵藉由一彈性薄膜定位，當施加 吸允力至裝置時’其允許磁鐵移動而分開。此步驟從儲 藏益開啟一流動路徑。然而，此機制相當地複雜，具有 迂迴的流動路徑而易於阻礙來自儲藏器的混合物的遞 达’且自然係為「二元的」’因為閥係為開啟或關閉任一 者。此並不提供使用者藉由改變吸吮的程度而調節流動 量的能力。第二範例係為彈簧偏移的活塞，其軸向地移 動以在一中央桿中開啟一通道。此轴向地可移動活塞實 際上並非所欲’因發現克服彈簧偏移力所冑㈣吮力的 級別太高而無法實際使用。而且，在開啟位置中的流動 路徑係從桿外、至活塞中、且再回到桿中，使其再一次 地某種程度上係迂迴的。第三範例依賴一磁性介面，其 上之力量係藉由f片的U克服，該等葉片圍繞著裝 201231104 置的軸旋轉，藉此沿著— 〇粮表面移動u，拉動磁性閥 物件離開其封口。再—4 ^ -人地，此遭遇複雜、缺乏控制、 及一迂迴流動路徑的問題。 US 5’027,808揭露-種吸入器，其中在一嘴片上吸吮 將拉扯—彈性隔膜，造成該彈性隔膜被吸入吸入器中朝 向嘴片。此依序移動-連結機制，其釋放—彈簧承載的 機制，彈簧提供力量以推擠容器來配給物質。連結機制 導入相當的複雜度且對配給機制佔據體積。配給器並無 提供可變控制’因其可為開或關任一者，且其需要藉由 使用者推擠一按壓钮來重新設定。 本公司本身較早應用的wo 2009/001082揭露兩個不 同的呼吸啟動裝置。㈣裝置之第一纟具有一對葉片系 統可圍繞著垂直於裝置的主軸的一軸旋轉，以對齊來自 儲存器與出口孔洞的一孔洞而能夠配給。此等裝置之第 二者具有一對樞紐葉片，其被向下吸吮抵抗返回彈簧的 動作，以便開啟流動路徑。此同時解決某些問題，因其 提供簡單的機制及一軸向流動路徑，吸吮以觸發裝置 所需的力量比較大，且因此使用者可在系統上輸出較少 的控制來釋放可改變的劑量，根據吸入的進氣而可大可 /J\ 〇 【發明内容】 本發明係針對一吸入器提供一改善的呼吸啟動閥，且 201231104 特定而言，係針對一模擬香煙β 根據本發明，提供一吸入器，其包含： 一可吸入混合物的一儲存器； 二體’其含有儲藏器且具有一出口端及一相反端； 一現合物流動路徑，其用於混合物的流動，從儲藏器 沿著：動路徑且於殼體的出口端處離開-混合物出口； 一彈性隔膜，其在殼體之中界定從-空氣人口至殼體 的出口端處的一空氣出口的一空氣流動路徑，該隔膜延 伸經過空氣流動人口朝向相對端，而將在隔膜的一側的 空氣流動路徑與裝載在隔膜的相對側上的殘餘物分開； 闕物件’其可與隔膜_起移動，且藉由一偏移力量 偏移至其關閉混合物流動路徑的一位置； 其中在出口端上吸吮降低在空氣流動腔室中的壓力， 從而抬昇閥物件抵抗偏移力量，以開啟混合物流動路 徑；及 其中一旦吸吮力終止，則偏移力量經安排以關閉混合 物流動路徑。 隔膜的使用延伸超越空氣流動入口且界定在負壓力的 情況下的一空氣流動路徑，而提供一可靠、簡單且敏感 的閥機制。 再者，經測試顯現此安排可配置成由使用者以比先前 技術的設計更小的力量操作，給予使用者對裝置更大的 控制，以及更快的回應，從而提供更類似於傳統香煙的 體驗。 201231104 較佳地’混合物流動路徑係一實質上筆直的路徑而無 V曲Λ提供將混合物更有效率地傳送至混合物出口。 為了更有效率地操作，彈性隔膜在鄰接空氣入口的區 域應特別有彈性且沿著其剩餘長度的區域應更堅硬。此 可藉由將在空氣入口區域的彈性隔膜作成較薄且在其剩 餘長度區域作成較厚而㈣地達成。彈性隔膜在其整體 寬度上可為更厚或可以縱向延伸的肋塑型。然而較佳 地，/。著隔膜的長度提供某些額外的強化物。此可採取 内。P強化肋’但較佳地係為一葉片，其沿著彈性隔膜的 主要的長度延伸。 閥物件可與葉片分開，但為了方便起見與葉片成一體 且可共同塑型，以確保一簡單的組成。 葉片在其兩端可為無連接地（free)，使其輕易地從一 個位置轉化成另—個位置。然而較佳地，葉片係樞紐地 固定於遠離空氣入口的端，使其在開啟及關閉位置之間 移動。此允_葉片在枢紐的四周行使最大的正切力量， 其影響其力矩且因此增加對使用者的呼吸的反應。 裝置的敏感性係大多由隔膜的表面積決定（若具有葉 片則包括葉片），其暴露於空氣流動路徑。薄膜因此較佳 地延伸為吸入器的總長度的至少四分之一長，且較佳地 為吸入器的總長度的至少三分之一長。 由於可移動閥物件由隔膜移動，可移動閥物件可以任 何方式配置，其可選擇地開啟或關閉混合物流動路徑。 其可為一磁性裝置或一電磁裝置，或可簡單地具有一通 201231104 透孔洞而可選擇地與混合物流動路徑對齊。然而較佳 地，混合物流動路徑的至少一部份係為一可變形管，其 可由閥物件選擇為被夾緊及被釋放。 儘管一單一隔膜與閥元件相關聯係為較佳地，但本發 明亦可以一對相對的隔膜及閥元件實行，當於出口端施 加吸吮時，其彼此遠離以便開啟混合物流動路徑。 較佳地，彈性隔膜經配置，使得所需的致動力量係介 於2Ν及20Ν之間，更加地為抓至贿，且最佳地實質 上為5Ν。 彈性隔膜暴露於空氣流動路徑在平面中的總面積（包 括葉片覆蓋的任何部份但除去鉗夾於周圍殼體的任何部 份）2係介於1〇0贿2及150職2之間，更加地為15〇 mm2-250 mm2,且最佳地實質上係為2〇〇mm2。此係降低 作用於隔膜上的有效面積，若具有葉片則包括葉片。提 供一適度大的面積減少開啟閥所需的吸吮力量。 葉片較佳地具有5 mm_1G職&高度，最佳地為8 _ ’且具# 1G_,_的長度，最佳地為25_。 於最窄點’隔膜的厚度較佳地可小於lmm，更加地為 介於^麵及〇-4職之間，且最佳地為0.1mm。隔膜 的相對硬度及彈性亦需要被標準化，以便使壓力下降均 專且等於吸食蘇^ AA M+. vo ,, 於卓的裝置的阻力。較佳i也，材料豆右 20-80A蕭耳的—蕭耳 八有 30-40A〇 料比值（Sh_丨.—），最佳地為 吸入器可為用於任何可 及入樂品混合物的一 藥物遞送 201231104 吸入器。然而，吸入器較佳地為具有—大致香煙形狀的 主體的一模擬香煙裝置。在此情況中，可吸入混合物較 4也i括尼古丁或一尼古丁衍生物或其鹽類。另一方 面，該吸入器可為複製吸煙的實體動作而在混合物中無 須尼古丁的一模擬香煙。或者，混合物可包括控制患者 的止痛藥、消炎藥、支氣;I；擴張劑、抗痙攣藥、抗病毒 藥或鸦片》 【實施方式】 本發明係關於用於一呼吸啟動香煙的出口閥的一改 善，且此處將僅具體地說明本發明的此態樣。對於香煙 裝置及其再裝滿機制的其餘結構的細節，請參考W〇 2009/001078 。 根據本發明的吸入器的第一範例係顯示於第1至3圖 中。 裝置具有一殼體1，其由第丨圖中所顯示的一主要底 座2及一包體物件3所組成。此係藉由標籤4而握於適 當位置。在殼體中，存在含有可吸入混合物的一儲藏器 5。此較佳地被加壓，但亦可以一未加壓的儲藏器與文托 利喷嘴（Venturi nozzle)結合而運作，以在儲藏器上產 生一增強的吸吮力里，或含有易於在室溫下揮發的物質 的一未加壓的儲藏器。其可透過填充閥6而如w〇 2009/001 082中所述而可重新裝滿，或該裝置可為一次性 10 201231104 使用裝置，或可經安排使得儲藏器5係一可替換組件。 呼吸啟動閥7係位於一出口端8及儲藏器5之間。呼 吸啟動闊經安排，使得當一使用者在出口端8吸吮時， 呼吸啟動閥7開啟，以允許來自儲藏器5的可吸入混合 物被吸食。 在出口端的殼體具有兩個孔洞。此等孔洞之第一者係 吸11允孔洞9 ’其與一腔室1 〇連通’而將於以下更詳細的 說明，且第二者係一出口孔洞11 ’可吸入混合物從此孔 洞配給，而亦於以下更詳細說明。從第3圖明顯可見， 出口孔洞11係提供於一分開的組件12上。 一出口路徑13係界定於儲藏器5及出口孔洞u之間。 出口路徑13的一部份係由可變形管狀元件14提供。 此管狀元件藉由現在將說明的一機制，在第1圖所顯示 的關閉位置及第2圖所顯示的開啟位置之間移動。 此機制包含一柩紐固定的葉片15及一薄膜16。此薄 膜係較佳地由注射模型作成，舉例而言，一 τρυ或τρΕ 材料，例如，Kraiburg Pharmaceutical grade ΤΕρ、或一 mediprene、Santoprene 或 Ne〇prene。樞紐固定的葉片於 最靠近出口端8的端具有一樞紐17，及沿著其長度且離 出口端越遠漸小的一中央加強肋18。或者，可具有兩個 或多個隔開的肋。在中點的四周，對葉片15提供一凹槽 19,用於容納一彈簀20,該彈著偏移葉片至第i圖所^ 示的關閉位置中。一顎片21係在凹槽19的下方，其具 有一三角的剖面而配置成將從葉片15提供的力量透過 201231104 一窄的面積施加至可變形管14。葉片15由隔膜16支撐， 其係藉由將顎片21符合通過隔膜甲的一洞且將在隔膜 上的凸座16A符合於葉片15上的一洞而加以支撑。隔 膜16於其端22、23密封至殼體《此密封腔室1〇而非密 封吸吮孔洞9。於端23處，隔膜16係呈皺紋的，以適 應該端介於開啟及關閉位置之間的動作。 薄膜16的下方側24係對大氣壓力開啟，作為透過殼 體1存在的一滲漏路徑，其未顯示於圖式中，因其延伸 於出口路徑1的四周且因此未顯示於第1及2圖的平面 中。 田使用者在第1圖所顯示的配置中的一裝置的出口 端8上吸洗時，g氣經由入口孔洞25被吸吩進入腔室 0且離開吸唆孔洞9，從而相對於隔膜^ 6下方的壓力來 降低此腔至中的壓力。在隔膜16上建立的壓力差足夠關 閉流動路徑。舉例而言，其可抵抗彈箸2〇的動作而抬昇 葉片15至第2圖中所顯示的位置。此將隔膜變形成第2 圖中所顯示的配置，且 > 糞 抬幵顎片21以允許可變形管開 啟’從而允許來自儲藏S ίΛ-ι* ° 的可吸入混合物沿著出口路 徑13透過可變形管14且读 且透過出口孔洞11而離開。由使 用者施加的吸吮的程度將決仝 厌將决疋葉片15移動的限度，且因 此決定使用者接收的混合物 ι 口物的薏。在使用者停止吸吮之 際’大氣壓力將透過吸吮？丨、、鬥Ω , 兄孔洞9返回至腔室10,且彈簣 20將葉片返回第1圖的位w，免 ’ 置從而夾緊管14為關閉。 12 201231104 【圖式簡單說明】 根據本發明的吸入器的範例現將參考隨附圖式而說 明，其中： 第1圖係在一關閉位置中的一第一吸入器經由一透視 圖的分區； 第2圖係在開啟位置中的一類似視圖； 第3圖係第1及2圖的吸入器的一展開的透視圖； 【主要元件符號說明】 1殼體 14 可變形管 2主要底座 15 葉片 3包體物件 16 薄膜 4標籤 17 極紐 5儲藏器 18 中央加強肋 6填充閥 19 凹槽 7呼吸啟動閥 20 彈簧 8出口端 21 顎片 9吸吮孔洞 22 端 10腔室 23 端 11出口孔洞 24 下方側 12分開的組件 25 孔洞 13流動路徑 13201231104 VI. Description of the Invention: TECHNICAL FIELD OF THE INVENTION The present invention relates to an inhaler. [Prior Art] The present invention has been specifically designed for a simulated cigarette device having a body of a substantially cigarette shape. However, the present invention relates to the development of an outlet valve for such a device, which has a wide range of applications in the field of inhalers, for example, medical inhalers for oral drug delivery such as asthma inhalers. In the field of cigarette substitutes, there have been several proposals for establishing a simulated cigarette. This device has several advantages of Shaw's traditional nicotine replacement money (such as patches and chewing gum), which re-establishes the physical action of smoking (which is important for a smoker) and can also More closely replicating the drug kinetic effects of a cigarette that an addicted smoker wants to deliver nicotine in a dose. Therefore, a smoker can obtain an "addiction" similar to a cigarette without having to face a slow release from a patch or chewing gum. 'It can't produce this addiction and lead to unpredictable taking and poor cravings and interruptions. ratio. A reservoir for simulating a cigarette having a respirable mixture and an outlet valve that can be triggered, for example, by pressing a button or biting the end of the cigarette. However, a preferred mechanism for opening the valve is to provide a breath-activated valve, as this ensures that the cigarette will only be dispensed when the user draws on the device in the form of a normal 201231104 cigarette. No. 4,393,884 discloses such a device having a large, resilient "tongue" having a flow path therethrough. The tab is offset to a -first position that is not aligned with the outlet of the cigarette and can be sucked to a second position aligned with the outlet of the cigarette to provide a flow path from the reservoir to the outlet. This - the device is difficult to seal in the first position. It will also require considerable force to suck the tongue to the open position to resist the action of a positioned spring and the relatively large mass of the tongue member, which will be difficult to return to the closed position 'meaning that the dispense is still after the suction force has been removed will continue. US 6 '889' 678 discloses another example of a simulated cigarette having a breath actuating valve. This patent discloses several examples. These examples have a pair of magnets, wherein the magnets are positioned by an elastic film that allows the magnet to move apart when a suction force is applied to the device. This step opens a flow path from the reservoir. However, this mechanism is quite complex, with a roundabout flow path that tends to hinder the delivery of the mixture from the reservoir' and is naturally "binary" because the valve system is either open or closed. This does not provide the user with the ability to adjust the amount of flow by varying the degree of sucking. The second example is a spring-biased piston that moves axially to open a passage in a central rod. This axially movable piston is actually not desirable. It has been found that it is too high to be practical to overcome the spring biasing force. Moreover, the flow path in the open position is from the outside of the rod, into the piston, and back into the rod, again to some extent. The third example relies on a magnetic interface on which the force is overcome by the U of the f-piece, which rotates around the axis of the 201231104, thereby moving u along the surface of the grain, pulling the magnetic valve object away from its seal. . Again - 4 ^ - human land, this encounters complex, lack of control, and a back-to-back flow path. US 5'027,808 discloses an inhaler wherein suction on a flap will pull the elastic diaphragm causing the elastic diaphragm to be drawn into the inhaler towards the mouthpiece. This sequential movement-linking mechanism, which releases the spring-loaded mechanism, provides the force to push the container to dispense the substance. The linking mechanism introduces considerable complexity and takes up volume for the dispensing mechanism. The dispenser does not provide variable control 'because it can be turned on or off, and it needs to be reset by pushing a push button by the user. The earlier application of the company itself, 2009/001082, revealed two different respiratory starting devices. (d) The first jaw of the apparatus has a pair of vane systems rotatable about an axis perpendicular to the main axis of the apparatus to align a hole from the reservoir and the exit aperture for dispensing. The first of these devices has a pair of hinge vanes that are sucked downwardly against the action of the return spring to open the flow path. At the same time, some problems are solved, because it provides a simple mechanism and an axial flow path, the force required to suck the device to trigger the device is relatively large, and thus the user can output less control on the system to release the variable dose. According to the inhaled intake air, it is possible to provide a modified breathing start valve for an inhaler, and 201231104, in particular, for a simulated cigarette β according to the present invention, An inhaler comprising: a reservoir of a respirable mixture; a body comprising a reservoir and having an outlet end and an opposite end; a ready flow path for the flow of the mixture from the reservoir Along the moving path and exiting at the outlet end of the housing - the mixture outlet; an elastic diaphragm defining an air flow path from the air population to an air outlet at the outlet end of the housing, The diaphragm extends through the air flow population towards the opposite end, and separates the air flow path on one side of the diaphragm from the residue loaded on the opposite side of the diaphragm; It can move with the diaphragm and is offset by a biasing force to a position where it closes the flow path of the mixture; wherein suction at the outlet end reduces the pressure in the air flow chamber, thereby raising the valve object against the bias The force is moved to open the mixture flow path; and once the suction force is terminated, the offset force is arranged to close the mixture flow path. The use of a diaphragm extends beyond the air flow inlet and defines an air flow path in the event of a negative pressure, providing a reliable, simple and sensitive valve mechanism. Furthermore, it has been shown that this arrangement can be configured to be operated by the user with less force than prior art designs, giving the user greater control over the device and a faster response, thereby providing a more similar to traditional cigarettes. Experience. 201231104 Preferably, the mixture flow path is a substantially straight path without V-curve providing more efficient delivery of the mixture to the mixture outlet. For more efficient operation, the elastomeric diaphragm should be particularly resilient in the region adjacent the air inlet and should be stiffer along the area of its remaining length. This can be achieved by making the elastic diaphragm in the air inlet region thin and making it thicker in the remaining length region. The elastic diaphragm may be thicker or longitudinally extendable in its overall width. Preferably, however. The length of the diaphragm provides some additional reinforcement. This can be taken within. The P-reinforced ribs' are preferably a blade that extends along the major length of the elastic membrane. The valve object can be separated from the blade, but it is integral with the blade for convenience and can be co-molded to ensure a simple composition. The blades can be free at both ends, allowing them to be easily converted from one location to another. Preferably, however, the blade is pivotally secured to the end remote from the air inlet to move between the open and closed positions. This allows the blade to exert the greatest tangential force around the hub, which affects its torque and thus increases the response to the user's breathing. The sensitivity of the device is mostly determined by the surface area of the diaphragm (including blades if it has blades) that are exposed to the air flow path. The film thus preferably extends at least a quarter of the total length of the inhaler and is preferably at least one third longer than the total length of the inhaler. Since the movable valve member is moved by the diaphragm, the movable valve member can be configured in any manner that selectively opens or closes the mixture flow path. It can be a magnetic device or an electromagnetic device, or can simply have a pass through the 201231104 through hole and optionally be aligned with the flow path of the mixture. Preferably, however, at least a portion of the flow path of the mixture is a deformable tube that is selected by the valve member to be clamped and released. Although a single diaphragm is preferred in connection with the valve member, the present invention can also be practiced with a pair of opposing diaphragm and valve members that are spaced apart from each other to open the mixture flow path when suction is applied at the outlet end. Preferably, the elastomeric membrane is configured such that the amount of actuation force required is between 2 and 20 inches, more preferably a bribe, and is preferably substantially 5 inches. The elastic diaphragm is exposed to the total area of the air flow path in the plane (including any part of the blade covering but removing any part clamped to the surrounding casing) 2 is between 1〇0 bribe 2 and 150 2, It is more 15 〇 mm 2 - 250 mm 2 and is optimally substantially 2 〇〇 mm 2 . This reduces the effective area acting on the diaphragm and includes the blade if it has blades. Providing a moderately large area reduces the suction force required to open the valve. The blade preferably has a height of 5 mm_1G & height, preferably 8 _ ' and has a length of #1G_,_, preferably 25_. The thickness of the separator at the narrowest point is preferably less than 1 mm, more preferably between the surface and the surface of the crucible, and is preferably 0.1 mm. The relative hardness and elasticity of the diaphragm also need to be standardized so that the pressure drop is equal to and equal to the resistance of the Su-AA M+. vo, Yu Zhuo device. Preferably, the material is also 20-80A of the right ear - the ear of the ear has a ratio of 30-40A (Sh_丨.-), preferably the inhaler can be used for any mixture of available products. One drug delivery 201231104 inhaler. However, the inhaler is preferably a simulated cigarette device having a body that is generally shaped like a cigarette. In this case, the inhalable mixture also includes nicotine or a nicotine derivative or a salt thereof. On the other hand, the inhaler can be a simulated cigarette that does not require nicotine in the mixture for the physical action of copying smoking. Alternatively, the mixture may include an analgesic, an anti-inflammatory drug, a bronchial agent for controlling a patient; I; an extender, an anticonvulsant, an antiviral or an opium. [Embodiment] The present invention relates to an outlet valve for a breath-starting cigarette. An improvement, and only this aspect of the invention will be specifically described herein. For details on the structure of the cigarette device and its refill mechanism, please refer to W〇 2009/001078. A first example of an inhaler according to the present invention is shown in Figures 1 to 3. The device has a housing 1 which is comprised of a main base 2 and an inclusive article 3 as shown in the figures. This is held in place by the label 4. In the housing, there is a reservoir 5 containing a respirable mixture. This is preferably pressurized, but it can also be operated in conjunction with an unpressurized reservoir in conjunction with a Venturi nozzle to create an enhanced suction force on the reservoir or to contain an easy temperature at room temperature. An unpressurized reservoir of volatile material. It may be refillable through filling valve 6 as described in WO 2009/001 082, or the device may be disposable 10 201231104, or may be arranged such that reservoir 5 is a replaceable component. The breath actuating valve 7 is located between an outlet end 8 and the reservoir 5. The breathing activation is arranged so that when a user sucks at the outlet end 8, the breath activation valve 7 is opened to allow the inhalable mixture from the reservoir 5 to be ingested. The housing at the outlet end has two holes. The first of these holes is a suction hole 9' which is in communication with a chamber 1' and will be described in more detail below, and the second is an outlet hole 11' from which the inhalable mixture is dispensed. It is also explained in more detail below. As is apparent from Fig. 3, the exit apertures 11 are provided on a separate assembly 12. An exit path 13 is defined between the reservoir 5 and the exit aperture u. A portion of the exit path 13 is provided by the deformable tubular element 14. The tubular member is moved between a closed position shown in Fig. 1 and an open position shown in Fig. 2 by a mechanism which will now be described. This mechanism includes a pair of fixed blades 15 and a film 16. The film is preferably formed from an injection mold, for example, a τρυ or τρΕ material, for example, Kraiburg Pharmaceutical grade ΤΕρ, or a mediprene, Santoprene or Ne〇prene. The hinged blade has a hinge 17 at the end closest to the outlet end 8, and a central reinforcing rib 18 along its length and further away from the outlet end. Alternatively, there may be two or more spaced apart ribs. Around the midpoint, the vane 15 is provided with a recess 19 for receiving a magazine 20 which deflects the vane into the closed position shown in Fig. i. A flap 21 is below the recess 19 and has a triangular cross-section configured to apply a force from the blade 15 to the deformable tube 14 through a narrow area of 201231104. The blade 15 is supported by a diaphragm 16 which is supported by conforming the cymbal 21 to a hole through the diaphragm and fitting the boss 16A on the diaphragm to a hole in the blade 15. The membrane 16 is sealed at its ends 22, 23 to the housing "this sealing chamber 1" instead of sealing the suction holes 9. At end 23, diaphragm 16 is wrinkled to accommodate the action between the open and closed positions. The lower side 24 of the membrane 16 is open to atmospheric pressure as a leak path through the housing 1 and is not shown in the drawings as it extends around the exit path 1 and is therefore not shown in the first and second In the plane of the graph. When the field user sucks up on the outlet end 8 of a device in the configuration shown in Fig. 1, g gas is sucked into the chamber 0 through the inlet hole 25 and leaves the suction hole 9, thereby being opposed to the diaphragm 6 The pressure below reduces the pressure in this chamber to medium. The pressure differential established on the diaphragm 16 is sufficient to close the flow path. For example, it can lift the blade 15 to the position shown in Fig. 2 against the action of the magazine 2〇. This deforms the diaphragm into the configuration shown in Figure 2, and > the shovel lifts the slab 21 to allow the deformable tube to open, thereby allowing the breathable mixture from the reservoir S Λ ι to pass through the exit path 13 The tube 14 is deformable and reads and exits through the exit aperture 11. The degree of suction applied by the user will inevitably limit the extent to which the blade 15 will be moved, and thus the enthalpy of the mixture received by the user is determined. When the user stops sucking, the atmospheric pressure will pass through the sucking? The 丨, 斗 Ω, the brother hole 9 is returned to the chamber 10, and the magazine 20 returns the blade to the position w of Fig. 1, so that the clamping tube 14 is closed. 12 201231104 [Simultaneous Description of the Drawings] An example of an inhaler according to the present invention will now be described with reference to the accompanying drawings in which: Figure 1 is a section of a first inhaler in a closed position via a perspective view; Figure 2 is a similar view in the open position; Figure 3 is an expanded perspective view of the inhaler of Figures 1 and 2; [Major component symbol description] 1 housing 14 deformable tube 2 main base 15 blade 3 inclusions 16 membrane 4 label 17 pole 5 reservoir 18 central reinforcement rib 6 filling valve 19 groove 7 breathing start valve 20 spring 8 outlet end 21 septum 9 suction hole 22 end 10 chamber 23 end 11 outlet hole 24 Lower side 12 separate assembly 25 hole 13 flow path 13